Works by Philip, Vivek M.

Results: 35

In vivo activity of the dual SYK/FLT3 inhibitor TAK‐659 against pediatric acute lymphoblastic leukemia xenografts.
Published in:
Pediatric Blood & Cancer, 2023, v. 70, n. 9, p. 1, doi. 10.1002/pbc.30503
By:
- Hughes, Keira;
- Evans, Kathryn;
- Earley, Eric J.;
- Smith, Christopher M.;
- Erickson, Stephen W.;
- Stearns, Tim;
- Philip, Vivek M.;
- Neuhauser, Steven B.;
- Chuang, Jeffrey H.;
- Jocoy, Emily L.;
- Bult, Carol J.;
- Teicher, Beverly A.;
- Smith, Malcolm A.;
- Lock, Richard B.
Publication type:
Article
Discovery of a Role for Rab3b in Habituation and Cocaine Induced Locomotor Activation in Mice Using Heterogeneous Functional Genomic Analysis.
Published in:
Frontiers in Neuroscience, 2020, v. 14, p. 1, doi. 10.3389/fnins.2020.00721
By:
- Bubier, Jason A.;
- Philip, Vivek M.;
- Dickson, Price E.;
- Mittleman, Guy;
- Chesler, Elissa J.
Publication type:
Article
A genetic locus complements resistance to Bordetella pertussis-induced histamine sensitization.
Published in:
Communications Biology, 2023, v. 6, n. 1, p. 1, doi. 10.1038/s42003-023-04603-w
By:
- Raza, Abbas;
- Diehl, Sean A.;
- Krementsov, Dimitry N.;
- Case, Laure K.;
- Li, Dawei;
- Kost, Jason;
- Ball, Robyn L.;
- Chesler, Elissa J.;
- Philip, Vivek M.;
- Huang, Rui;
- Chen, Yan;
- Ma, Runlin;
- Tyler, Anna L.;
- Mahoney, J. Matthew;
- Blankenhorn, Elizabeth P.;
- Teuscher, Cory
Publication type:
Article
A Microbe Associated with Sleep Revealed by a Novel Systems Genetic Analysis of the Microbiome in Collaborative Cross Mice.
Published in:
Genetics, 2020, v. 214, n. 3, p. 719, doi. 10.1534/genetics.119.303013
By:
- Bubier, Jason A.;
- Philip, Vivek M.;
- Quince, Christopher;
- Campbell, James;
- Yanjiao Zhou;
- Vishnivetskaya, Tatiana;
- Duvvuru, Suman;
- Hageman Blair, Rachel;
- Ndukum, Juliet;
- Donohue, Kevin D.;
- Foster, Carmen M.;
- Mellert, David J.;
- Weinstock, George;
- Culiat, Cymbeline T.;
- O'Hara, Bruce F.;
- Palumbo, Anthony V.;
- Podar, Mircea;
- Chesler, Elissa J.
Publication type:
Article
A Bayesian Framework for Generalized Linear Mixed Modeling Identifies New Candidate Loci for Late-Onset Alzheimer's Disease.
Published in:
Genetics, 2018, v. 209, n. 1, p. 51, doi. 10.1534/genetics.117.300673
By:
- Xulong Wang;
- Philip, Vivek M.;
- Ananda, Guruprasad;
- White, Charles C.;
- Malhotra, Ankit;
- Michalski, Paul J.;
- Murthy Karuturi, Krishna R.;
- Chintalapudi, Sumana R.;
- Acklin, Casey;
- Sasner, Michael;
- Bennett, David A.;
- De Jager, Philip L.;
- Howell, Gareth R.;
- Carter, Gregory W.
Publication type:
Article
Identification of Pre-symptomatic Gene Signatures That Predict Resilience to Cognitive Decline in the Genetically Diverse AD-BXD Model.
Published in:
Frontiers in Genetics, 2019, p. N.PAG, doi. 10.3389/fgene.2019.00035
By:
- Neuner, Sarah M.;
- Heuer, Sarah E.;
- Zhang, Ji-Gang;
- Philip, Vivek M.;
- Kaczorowski, Catherine C.
Publication type:
Article
Discovery of transgene insertion sites by high throughput sequencing of mate pair libraries.
Published in:
BMC Genomics, 2014, v. 15, n. 1, p. 1, doi. 10.1186/1471-2164-15-367
By:
- Srivastava, Anuj;
- Philip, Vivek M.;
- Greenstein, Ian;
- Rowe, Lucy B.;
- Barter, Mary;
- Lutz, Cathleen;
- Reinholdt, Laura G.
Publication type:
Article
Genetic variation in hippocampal microRNA expression differences in C57BL/6 J X DBA/2 J (BXD) recombinant inbred mouse strains.
Published in:
BMC Genomics, 2012, v. 13, n. 1, p. 476, doi. 10.1186/1471-2164-13-476
By:
- Parsons, Michael J.;
- Grimm, Christina;
- Paya-Cano, Jose L.;
- Fernandes, Cathy;
- Liu, Lin;
- Philip, Vivek M.;
- Chesler, Elissa J.;
- Nietfeld, Wilfried;
- Lehrach, Hans;
- Schalkwyk, Leonard C.
Publication type:
Article
Gene expression genetics of the striatum of Diversity Outbred mice.
Published in:
Scientific Data, 2023, v. 10, n. 1, p. 1, doi. 10.1038/s41597-023-02426-2
By:
- Philip, Vivek M.;
- He, Hao;
- Saul, Michael C.;
- Dickson, Price E.;
- Bubier, Jason A.;
- Chesler, Elissa J.
Publication type:
Article
The collaborative cross strains and their founders vary widely in cocaine-induced behavioral sensitization.
Published in:
Frontiers in Behavioral Neuroscience, 2022, v. 16, p. 1, doi. 10.3389/fnbeh.2022.886524
By:
- Schoenrock, Sarah A.;
- Gagnon, Leona;
- Olson, Ashley;
- Leonardo, Michael;
- Philip, Vivek M.;
- Hao He;
- Reinholdt, Laura G.;
- Rizzo, Stacey J. Sukoff;
- Jentsch, James D.;
- Chesler, Elissa J.;
- Tarantino, Lisa M.
Publication type:
Article
CAPE: An R Package for Combined Analysis of Pleiotropy and Epistasis.
Published in:
PLoS Computational Biology, 2013, v. 9, n. 10, p. 1, doi. 10.1371/journal.pcbi.1003270
By:
- Tyler, Anna L.;
- Lu, Wei;
- Hendrick, Justin J.;
- Philip, Vivek M.;
- Carter, Gregory W.
Publication type:
Article
Discovery and validation of genes driving drug‐intake and related behavioral traits in mice.
Published in:
Genes, Brain & Behavior, 2024, v. 23, n. 1, p. 1, doi. 10.1111/gbb.12875
By:
- Roy, Tyler A.;
- Bubier, Jason A.;
- Dickson, Price E.;
- Wilcox, Troy D.;
- Ndukum, Juliet;
- Clark, James W.;
- Sukoff Rizzo, Stacey J.;
- Crabbe, John C.;
- Denegre, James M.;
- Svenson, Karen L.;
- Braun, Robert E.;
- Kumar, Vivek;
- Murray, Stephen A.;
- White, Jacqueline K.;
- Philip, Vivek M.;
- Chesler, Elissa J.
Publication type:
Article
Heritable variation in locomotion, reward sensitivity and impulsive behaviors in a genetically diverse inbred mouse panel.
Published in:
Genes, Brain & Behavior, 2021, v. 20, n. 8, p. 1, doi. 10.1111/gbb.12773
By:
- Bailey, Lauren S.;
- Bagley, Jared R.;
- Dodd, Rainy;
- Olson, Ashley;
- Bolduc, Mikayla;
- Philip, Vivek M.;
- Reinholdt, Laura G.;
- Sukoff Rizzo, Stacey J.;
- Tarantino, Lisa;
- Gagnon, Leona;
- Chesler, Elissa J.;
- Jentsch, James David
Publication type:
Article
Characterization of genetically complex Collaborative Cross mouse strains that model divergent locomotor activating and reinforcing properties of cocaine.
Published in:
Psychopharmacology, 2020, v. 237, n. 4, p. 979, doi. 10.1007/s00213-019-05429-3
By:
- Schoenrock, Sarah A.;
- Kumar, Padam;
- Gómez-A, Alexander;
- Dickson, Price E.;
- Kim, Sam-Moon;
- Bailey, Lauren;
- Neira, Sofia;
- Riker, Kyle D.;
- Farrington, Joseph;
- Gaines, Christiann H.;
- Khan, Saad;
- Wilcox, Troy D.;
- Roy, Tyler A.;
- Leonardo, Michael R.;
- Olson, Ashley A.;
- Gagnon, Leona H.;
- Philip, Vivek M.;
- Valdar, William;
- de Villena, Fernando Pardo-Manuel;
- Jentsch, James D.
Publication type:
Article
Molecular Identification of Collagen 17a1 as a Major Genetic Modifier of Laminin Gamma 2 Mutation-Induced Junctional Epidermolysis Bullosa in Mice.
Published in:
PLoS Genetics, 2014, v. 10, n. 2, p. 1, doi. 10.1371/journal.pgen.1004068
By:
- Sproule, Thomas J.;
- Bubier, Jason A.;
- Grandi, Fiorella C.;
- Sun, Victor Z.;
- Philip, Vivek M.;
- McPhee, Caroline G.;
- Adkins, Elisabeth B.;
- Sundberg, John P.;
- Roopenian, Derry C.
Publication type:
Article
Seven naturally variant loci serve as genetic modifiers of Lamc2<sup>jeb</sup> induced non-Herlitz junctional Epidermolysis Bullosa in mice.
Published in:
PLoS ONE, 2023, v. 18, n. 7, p. 1, doi. 10.1371/journal.pone.0288263
By:
- Sproule, Thomas J.;
- Philip, Vivek M.;
- Chaudhry, Nabig A.;
- Roopenian, Derry C.;
- Sundberg, John P.
Publication type:
Article
Identification of quantitative trait loci for survival in the mutant dynactin p150Glued mouse model of motor neuron disease.
Published in:
PLoS ONE, 2022, v. 17, n. 9, p. 1, doi. 10.1371/journal.pone.0274615
By:
- Alexander, Guillermo M.;
- Heiman-Patterson, Terry D.;
- Bearoff, Frank;
- Sher, Roger B.;
- Hennessy, Laura;
- Terek, Shannon;
- Caccavo, Nicole;
- Cox, Gregory A.;
- Philip, Vivek M.;
- Blankenhorn, Elizabeth A.
Publication type:
Article
Genetic Mapping of Vocalization to a Series of Increasing Acute Footshocks Using B6.A Consomic and B6.D2 Congenic Mouse Strains.
Published in:
Behavior Genetics, 2008, v. 38, n. 4, p. 417, doi. 10.1007/s10519-008-9210-7
By:
- Matthews, Douglas B.;
- Chesler, Elissa J.;
- Cook, Melloni N.;
- Cockroft, Jody;
- Philip, Vivek M.;
- Goldowitz, Dan
Publication type:
Article
Action detection using a neural network elucidates the genetics of mouse grooming behavior.
Published in:
eLife, 2021, p. 1, doi. 10.7554/eLife.63207
By:
- Geuther, Brian Q.;
- Peer, Asaf;
- Hao He;
- Sabnis, Gautam;
- Philip, Vivek M.;
- Kumar, Vivek
Publication type:
Article
Mouse Phenome Database: towards a more FAIR-compliant and TRUST-worthy data repository and tool suite for phenotypes and genotypes.
Published in:
Nucleic Acids Research, 2023, v. 51, n. D1, p. D1067, doi. 10.1093/nar/gkac1007
By:
- Bogue, Molly A;
- Ball, Robyn L;
- Philip, Vivek M;
- Walton, David O;
- Dunn, Matthew H;
- Kolishovski, Georgi;
- Lamoureux, Anna;
- Gerring, Matthew;
- Liang, Hongping;
- Emerson, Jake;
- Stearns, Tim;
- He, Hao;
- Mukherjee, Gaurab;
- Bluis, John;
- Desai, Sejal;
- Sundberg, Beth;
- Kadakkuzha, Beena;
- Kunde-Ramamoorthy, Govindarajan;
- Chesler, Elissa J
Publication type:
Article
Genome-wide association for testis weight in the diversity outbred mouse population.
Published in:
Mammalian Genome, 2018, v. 29, n. 5/6, p. 310, doi. 10.1007/s00335-018-9745-8
By:
- Yuan, Joshua T.;
- Gatti, Daniel M.;
- Philip, Vivek M.;
- Kasparek, Steven;
- Kreuzman, Andrew M.;
- Mansky, Benjamin;
- Sharif, Kayvon;
- Taterra, Dominik;
- Taylor, Walter M.;
- Thomas, Mary;
- Ward, Jeremy O.;
- Holmes, Andrew;
- Chesler, Elissa J.;
- Parker, Clarissa C.
Publication type:
Article
The Collaborative Cross at Oak Ridge National Laboratory: developing a powerful resource for systems genetics.
Published in:
Mammalian Genome, 2008, v. 19, n. 6, p. 382, doi. 10.1007/s00335-008-9135-8
By:
- Chesler, Elissa J.;
- Miller, Darla R.;
- Branstetter, Lisa R.;
- Galloway, Leslie D.;
- Jackson, Barbara L.;
- Philip, Vivek M.;
- Voy, Brynn H.;
- Culiat, Cymbeline T.;
- Threadgill, David W.;
- Williams, Robert W.;
- Churchill, Gary A.;
- Johnson, Dabney K.;
- Manly, Kenneth F.
Publication type:
Article
High-throughput measurement of fibroblast rhythms reveals genetic heritability of circadian phenotypes in diversity outbred mice and their founder strains.
Published in:
Scientific Reports, 2021, v. 11, n. 1, p. 1, doi. 10.1038/s41598-021-82069-8
By:
- Kim, Sam-Moon;
- Vadnie, Chelsea A.;
- Philip, Vivek M.;
- Gagnon, Leona H.;
- Chowdari, Kodavali V.;
- Chesler, Elissa J.;
- McClung, Colleen A.;
- Logan, Ryan W.
Publication type:
Article
Genetic variation regulates opioid-induced respiratory depression in mice.
Published in:
Scientific Reports, 2020, v. 10, n. 1, p. N.PAG, doi. 10.1038/s41598-020-71804-2
By:
- Bubier, Jason A.;
- He, Hao;
- Philip, Vivek M.;
- Roy, Tyler;
- Hernandez, Christian Monroy;
- Bernat, Rebecca;
- Donohue, Kevin D.;
- O'Hara, Bruce F.;
- Chesler, Elissa J.
Publication type:
Article
Mouse Phenome Database: a data repository and analysis suite for curated primary mouse phenotype data.
Published in:
Nucleic Acids Research, 2020, v. 48, n. D1, p. D716, doi. 10.1093/nar/gkz1032
By:
- Bogue, Molly A;
- Philip, Vivek M;
- Walton, David O;
- Grubb, Stephen C;
- Dunn, Matthew H;
- Kolishovski, Georgi;
- Emerson, Jake;
- Mukherjee, Gaurab;
- Stearns, Timothy;
- He, Hao;
- Sinha, Vinita;
- Kadakkuzha, Beena;
- Kunde-Ramamoorthy, Govindarajan;
- Chesler, Elissa J
Publication type:
Article
Mouse Phenome Database: an integrative database and analysis suite for curated empirical phenotype data from laboratory mice.
Published in:
Nucleic Acids Research, 2018, v. 46, n. D1, p. D843, doi. 10.1093/nar/gkx1082
By:
- Bogue, Molly A;
- Grubb, Stephen C;
- Walton, David O;
- Philip, Vivek M;
- Kolishovski, Georgi;
- Stearns, Tim;
- Dunn, Matthew H;
- Skelly, Daniel A;
- Kadakkuzha, Beena;
- TeHennepe, Gregg
Publication type:
Article
Chromosome Y‐haplotype mediates cognitive resilience and differential expression of transposable elements in 5xFAD‐carrying AD‐BXD males.
Published in:
Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2023, v. 19, p. 1, doi. 10.1002/alz.082951
By:
- Boas, Stephanie M.;
- Saul, Michael C.;
- Anderson, David;
- Philip, Vivek M.;
- Ramirez, Paulino;
- Frost, Bess;
- Beck, Christine R.;
- Kaczorowski, Catherine C.
Publication type:
Article
Early synaptic gene expression downregulation in the frontal cortex distinguishes Alzheimer's disease from normal aging in a genetically diverse mouse population.
Published in:
Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2023, v. 19, p. 1, doi. 10.1002/alz.065931
By:
- Dunn, Amy R;
- Ouellette, Andrew R;
- Hadad, Niran;
- Zhang, Jigang;
- Philip, Vivek M.;
- O'Connell, Kristen;
- Kaczorowski, Catherine C.
Publication type:
Article
Conserved cell‐type specific signature of resilience to Alzheimer's disease nominates role for excitatory cortical neurons.
Published in:
Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2022, v. 18, n. 4, p. 1, doi. 10.1002/alz.069370
By:
- Telpoukhovskaia, Maria;
- Hadad, Niran;
- Gurdon, Brianna;
- Dai, Miko;
- Ouellette, Andrew R;
- Neuner, Sarah;
- Dunn, Amy R;
- Hansen, Shania L;
- Wu, Yiyang;
- Dumitrescu, Logan;
- O'Connell, Kristen MS;
- Dammer, Eric B;
- Seyfried, Nicholas T.;
- Muzumdar, Sukalp;
- Gillis, Jesse;
- Robson, Paul;
- Zhang, Jigang;
- Hohman, Timothy J.;
- Philip, Vivek M.;
- Menon, Vilas
Publication type:
Article
Single amino acid change in the receptor binding domain of mouse APOE results in altered protein dynamics and worsened AD‐related cognitive impairment.
Published in:
Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2022, v. 18, n. 4, p. 1, doi. 10.1002/alz.067225
By:
- Kaczorowski, Catherine C.;
- Singh, Surjeet;
- Kaur, Harpreet;
- Hadad, Niran;
- Telpoukhovskaia, Maria;
- Zhang, Jigang;
- Philip, Vivek M.;
- O'Connell, Kristen MS;
- Levine, Zachary;
- Dunn, Amy R
Publication type:
Article
Identification of transcriptional signatures of cognitive resilience using single nucleus RNA sequencing.
Published in:
Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2022, v. 18, n. 3, p. 1, doi. 10.1002/alz.065947
By:
- Hadad, Niran;
- Telpoukhovskaia, Maria;
- Zhang, Jigang;
- Samuels, Michael;
- Robson, Paul;
- Philip, Vivek M.;
- Kaczorowski, Catherine C.
Publication type:
Article
Disentangling the determinants of transposable element expression in cognitive aging and Alzheimer's disease deficits using the AD‐BXD mouse population.
Published in:
Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2021, v. 17, n. 3, p. 1, doi. 10.1002/alz.053048
By:
- Philip, Vivek M.;
- Anderson, David;
- Ramirez, Paulino;
- Frost, Bess;
- Kaczorowski, Catherine C.
Publication type:
Article
APOE variant in the receptor binding domain confers cognitive resilience to familial Alzheimer's mutations and cell‐type specific gene expression changes in the hippocampus.
Published in:
Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2021, v. 17, n. 3, p. 1, doi. 10.1002/alz.051794
By:
- King, Jillian L.;
- Anderson, David;
- Zhang, Jigang;
- Telpoukhovskaia, Maria;
- Hadad, Niran;
- Dunn, Amy R;
- Dumitrescu, Logan;
- Hohman, Timothy J.;
- O'Connell, Kristen MS;
- Philip, Vivek M.;
- Kaczorowski, Catherine C.
Publication type:
Article
Minor genomic differences between related B6 and B10 mice affect severity of schistosome infection by governing the mode of dendritic cell activation.
Published in:
European Journal of Immunology, 2015, v. 45, n. 8, p. 2312, doi. 10.1002/eji.201545547
By:
- Smith, Patrick M.;
- Sproule, Thomas J.;
- Philip, Vivek M.;
- Roopenian, Derry C.;
- Stadecker, Miguel J.
Publication type:
Article
Supplementing High-Density SNP Microarrays for Additional Coverage of Disease-Related Genes: Addiction as a Paradigm.
Published in:
PLoS ONE, 2009, v. 4, n. 4, p. 1, doi. 10.1371/journal.pone.0005225
By:
- Saccone, Scott F.;
- Bierut, Laura J.;
- Chesler, Elissa J.;
- Kalivas, Peter W.;
- Lerman, Caryn;
- Saccone, Nancy L.;
- Uhl, George R.;
- Chuan-Yun Li;
- Philip, Vivek M.;
- Edenberg, Howard J.;
- Sherry, Stephen T.;
- Feolo, Michael;
- Moyzis, Robert K.;
- Rutter, Joni L.
Publication type:
Article