Works by Philip, Vivek M.

Results: 35

Characterization of genetically complex Collaborative Cross mouse strains that model divergent locomotor activating and reinforcing properties of cocaine.

Published in:

Psychopharmacology, 2020, v. 237, n. 4, p. 979, doi. 10.1007/s00213-019-05429-3

By:

Schoenrock, Sarah A.;
Kumar, Padam;
Gómez-A, Alexander;
Dickson, Price E.;
Kim, Sam-Moon;
Bailey, Lauren;
Neira, Sofia;
Riker, Kyle D.;
Farrington, Joseph;
Gaines, Christiann H.;
Khan, Saad;
Wilcox, Troy D.;
Roy, Tyler A.;
Leonardo, Michael R.;
Olson, Ashley A.;
Gagnon, Leona H.;
Philip, Vivek M.;
Valdar, William;
de Villena, Fernando Pardo-Manuel;
Jentsch, James D.

Publication type:

Article

Seven naturally variant loci serve as genetic modifiers of Lamc2<sup>jeb</sup> induced non-Herlitz junctional Epidermolysis Bullosa in mice.

Published in:

PLoS ONE, 2023, v. 18, n. 7, p. 1, doi. 10.1371/journal.pone.0288263

By:

Sproule, Thomas J.;
Philip, Vivek M.;
Chaudhry, Nabig A.;
Roopenian, Derry C.;
Sundberg, John P.

Publication type:

Article

Genetic Mapping of Vocalization to a Series of Increasing Acute Footshocks Using B6.A Consomic and B6.D2 Congenic Mouse Strains.

Published in:

Behavior Genetics, 2008, v. 38, n. 4, p. 417, doi. 10.1007/s10519-008-9210-7

By:

Matthews, Douglas B.;
Chesler, Elissa J.;
Cook, Melloni N.;
Cockroft, Jody;
Philip, Vivek M.;
Goldowitz, Dan

Publication type:

Article

Action detection using a neural network elucidates the genetics of mouse grooming behavior.

Published in:

eLife, 2021, p. 1, doi. 10.7554/eLife.63207

By:

Geuther, Brian Q.;
Peer, Asaf;
Hao He;
Sabnis, Gautam;
Philip, Vivek M.;
Kumar, Vivek

Publication type:

Article

High-throughput measurement of fibroblast rhythms reveals genetic heritability of circadian phenotypes in diversity outbred mice and their founder strains.

Published in:

Scientific Reports, 2021, v. 11, n. 1, p. 1, doi. 10.1038/s41598-021-82069-8

By:

Kim, Sam-Moon;
Vadnie, Chelsea A.;
Philip, Vivek M.;
Gagnon, Leona H.;
Chowdari, Kodavali V.;
Chesler, Elissa J.;
McClung, Colleen A.;
Logan, Ryan W.

Publication type:

Article

Genetic variation regulates opioid-induced respiratory depression in mice.

Published in:

Scientific Reports, 2020, v. 10, n. 1, p. N.PAG, doi. 10.1038/s41598-020-71804-2

By:

Bubier, Jason A.;
He, Hao;
Philip, Vivek M.;
Roy, Tyler;
Hernandez, Christian Monroy;
Bernat, Rebecca;
Donohue, Kevin D.;
O'Hara, Bruce F.;
Chesler, Elissa J.

Publication type:

Article

Identification of Pre-symptomatic Gene Signatures That Predict Resilience to Cognitive Decline in the Genetically Diverse AD-BXD Model.

Published in:

Frontiers in Genetics, 2019, p. N.PAG, doi. 10.3389/fgene.2019.00035

By:

Neuner, Sarah M.;
Heuer, Sarah E.;
Zhang, Ji-Gang;
Philip, Vivek M.;
Kaczorowski, Catherine C.

Publication type:

Article

Discovery of transgene insertion sites by high throughput sequencing of mate pair libraries.

Published in:

BMC Genomics, 2014, v. 15, n. 1, p. 1, doi. 10.1186/1471-2164-15-367

By:

Srivastava, Anuj;
Philip, Vivek M.;
Greenstein, Ian;
Rowe, Lucy B.;
Barter, Mary;
Lutz, Cathleen;
Reinholdt, Laura G.

Publication type:

Article

Genetic variation in hippocampal microRNA expression differences in C57BL/6 J X DBA/2 J (BXD) recombinant inbred mouse strains.

Published in:

BMC Genomics, 2012, v. 13, n. 1, p. 476, doi. 10.1186/1471-2164-13-476

By:

Parsons, Michael J.;
Grimm, Christina;
Paya-Cano, Jose L.;
Fernandes, Cathy;
Liu, Lin;
Philip, Vivek M.;
Chesler, Elissa J.;
Nietfeld, Wilfried;
Lehrach, Hans;
Schalkwyk, Leonard C.

Publication type:

Article

CAPE: An R Package for Combined Analysis of Pleiotropy and Epistasis.

Published in:

PLoS Computational Biology, 2013, v. 9, n. 10, p. 1, doi. 10.1371/journal.pcbi.1003270

By:

Tyler, Anna L.;
Lu, Wei;
Hendrick, Justin J.;
Philip, Vivek M.;
Carter, Gregory W.

Publication type:

Article

Gene expression genetics of the striatum of Diversity Outbred mice.

Published in:

Scientific Data, 2023, v. 10, n. 1, p. 1, doi. 10.1038/s41597-023-02426-2

By:

Philip, Vivek M.;
He, Hao;
Saul, Michael C.;
Dickson, Price E.;
Bubier, Jason A.;
Chesler, Elissa J.

Publication type:

Article

In vivo activity of the dual SYK/FLT3 inhibitor TAK‐659 against pediatric acute lymphoblastic leukemia xenografts.

Published in:

Pediatric Blood & Cancer, 2023, v. 70, n. 9, p. 1, doi. 10.1002/pbc.30503

By:

Hughes, Keira;
Evans, Kathryn;
Earley, Eric J.;
Smith, Christopher M.;
Erickson, Stephen W.;
Stearns, Tim;
Philip, Vivek M.;
Neuhauser, Steven B.;
Chuang, Jeffrey H.;
Jocoy, Emily L.;
Bult, Carol J.;
Teicher, Beverly A.;
Smith, Malcolm A.;
Lock, Richard B.

Publication type:

Article

A genetic locus complements resistance to Bordetella pertussis-induced histamine sensitization.

Published in:

Communications Biology, 2023, v. 6, n. 1, p. 1, doi. 10.1038/s42003-023-04603-w

By:

Raza, Abbas;
Diehl, Sean A.;
Krementsov, Dimitry N.;
Case, Laure K.;
Li, Dawei;
Kost, Jason;
Ball, Robyn L.;
Chesler, Elissa J.;
Philip, Vivek M.;
Huang, Rui;
Chen, Yan;
Ma, Runlin;
Tyler, Anna L.;
Mahoney, J. Matthew;
Blankenhorn, Elizabeth P.;
Teuscher, Cory

Publication type:

Article

Identification of quantitative trait loci for survival in the mutant dynactin p150Glued mouse model of motor neuron disease.

Published in:

PLoS ONE, 2022, v. 17, n. 9, p. 1, doi. 10.1371/journal.pone.0274615

By:

Alexander, Guillermo M.;
Heiman-Patterson, Terry D.;
Bearoff, Frank;
Sher, Roger B.;
Hennessy, Laura;
Terek, Shannon;
Caccavo, Nicole;
Cox, Gregory A.;
Philip, Vivek M.;
Blankenhorn, Elizabeth A.

Publication type:

Article

Discovery and validation of genes driving drug‐intake and related behavioral traits in mice.

Published in:

Genes, Brain & Behavior, 2024, v. 23, n. 1, p. 1, doi. 10.1111/gbb.12875

By:

Roy, Tyler A.;
Bubier, Jason A.;
Dickson, Price E.;
Wilcox, Troy D.;
Ndukum, Juliet;
Clark, James W.;
Sukoff Rizzo, Stacey J.;
Crabbe, John C.;
Denegre, James M.;
Svenson, Karen L.;
Braun, Robert E.;
Kumar, Vivek;
Murray, Stephen A.;
White, Jacqueline K.;
Philip, Vivek M.;
Chesler, Elissa J.

Publication type:

Article

Heritable variation in locomotion, reward sensitivity and impulsive behaviors in a genetically diverse inbred mouse panel.

Published in:

Genes, Brain & Behavior, 2021, v. 20, n. 8, p. 1, doi. 10.1111/gbb.12773

By:

Bailey, Lauren S.;
Bagley, Jared R.;
Dodd, Rainy;
Olson, Ashley;
Bolduc, Mikayla;
Philip, Vivek M.;
Reinholdt, Laura G.;
Sukoff Rizzo, Stacey J.;
Tarantino, Lisa;
Gagnon, Leona;
Chesler, Elissa J.;
Jentsch, James David

Publication type:

Article

Mouse Phenome Database: towards a more FAIR-compliant and TRUST-worthy data repository and tool suite for phenotypes and genotypes.

Published in:

Nucleic Acids Research, 2023, v. 51, n. D1, p. D1067, doi. 10.1093/nar/gkac1007

By:

Bogue, Molly A;
Ball, Robyn L;
Philip, Vivek M;
Walton, David O;
Dunn, Matthew H;
Kolishovski, Georgi;
Lamoureux, Anna;
Gerring, Matthew;
Liang, Hongping;
Emerson, Jake;
Stearns, Tim;
He, Hao;
Mukherjee, Gaurab;
Bluis, John;
Desai, Sejal;
Sundberg, Beth;
Kadakkuzha, Beena;
Kunde-Ramamoorthy, Govindarajan;
Chesler, Elissa J

Publication type:

Article

Mouse Phenome Database: a data repository and analysis suite for curated primary mouse phenotype data.

Published in:

Nucleic Acids Research, 2020, v. 48, n. D1, p. D716, doi. 10.1093/nar/gkz1032

By:

Bogue, Molly A;
Philip, Vivek M;
Walton, David O;
Grubb, Stephen C;
Dunn, Matthew H;
Kolishovski, Georgi;
Emerson, Jake;
Mukherjee, Gaurab;
Stearns, Timothy;
He, Hao;
Sinha, Vinita;
Kadakkuzha, Beena;
Kunde-Ramamoorthy, Govindarajan;
Chesler, Elissa J

Publication type:

Article

Mouse Phenome Database: an integrative database and analysis suite for curated empirical phenotype data from laboratory mice.

Published in:

Nucleic Acids Research, 2018, v. 46, n. D1, p. D843, doi. 10.1093/nar/gkx1082

By:

Bogue, Molly A;
Grubb, Stephen C;
Walton, David O;
Philip, Vivek M;
Kolishovski, Georgi;
Stearns, Tim;
Dunn, Matthew H;
Skelly, Daniel A;
Kadakkuzha, Beena;
TeHennepe, Gregg

Publication type:

Article

Discovery of a Role for Rab3b in Habituation and Cocaine Induced Locomotor Activation in Mice Using Heterogeneous Functional Genomic Analysis.

Published in:

Frontiers in Neuroscience, 2020, v. 14, p. 1, doi. 10.3389/fnins.2020.00721

By:

Bubier, Jason A.;
Philip, Vivek M.;
Dickson, Price E.;
Mittleman, Guy;
Chesler, Elissa J.

Publication type:

Article

Supplementing High-Density SNP Microarrays for Additional Coverage of Disease-Related Genes: Addiction as a Paradigm.

Published in:

PLoS ONE, 2009, v. 4, n. 4, p. 1, doi. 10.1371/journal.pone.0005225

By:

Saccone, Scott F.;
Bierut, Laura J.;
Chesler, Elissa J.;
Kalivas, Peter W.;
Lerman, Caryn;
Saccone, Nancy L.;
Uhl, George R.;
Chuan-Yun Li;
Philip, Vivek M.;
Edenberg, Howard J.;
Sherry, Stephen T.;
Feolo, Michael;
Moyzis, Robert K.;
Rutter, Joni L.

Publication type:

Article

The collaborative cross strains and their founders vary widely in cocaine-induced behavioral sensitization.

Published in:

Frontiers in Behavioral Neuroscience, 2022, v. 16, p. 1, doi. 10.3389/fnbeh.2022.886524

By:

Schoenrock, Sarah A.;
Gagnon, Leona;
Olson, Ashley;
Leonardo, Michael;
Philip, Vivek M.;
Hao He;
Reinholdt, Laura G.;
Rizzo, Stacey J. Sukoff;
Jentsch, James D.;
Chesler, Elissa J.;
Tarantino, Lisa M.

Publication type:

Article

Chromosome Y‐haplotype mediates cognitive resilience and differential expression of transposable elements in 5xFAD‐carrying AD‐BXD males.

Published in:

Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2023, v. 19, p. 1, doi. 10.1002/alz.082951

By:

Boas, Stephanie M.;
Saul, Michael C.;
Anderson, David;
Philip, Vivek M.;
Ramirez, Paulino;
Frost, Bess;
Beck, Christine R.;
Kaczorowski, Catherine C.

Publication type:

Article

Early synaptic gene expression downregulation in the frontal cortex distinguishes Alzheimer's disease from normal aging in a genetically diverse mouse population.

Published in:

Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2023, v. 19, p. 1, doi. 10.1002/alz.065931

By:

Dunn, Amy R;
Ouellette, Andrew R;
Hadad, Niran;
Zhang, Jigang;
Philip, Vivek M.;
O'Connell, Kristen;
Kaczorowski, Catherine C.

Publication type:

Article

Conserved cell‐type specific signature of resilience to Alzheimer's disease nominates role for excitatory cortical neurons.

Published in:

Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2022, v. 18, n. 4, p. 1, doi. 10.1002/alz.069370

By:

Telpoukhovskaia, Maria;
Hadad, Niran;
Gurdon, Brianna;
Dai, Miko;
Ouellette, Andrew R;
Neuner, Sarah;
Dunn, Amy R;
Hansen, Shania L;
Wu, Yiyang;
Dumitrescu, Logan;
O'Connell, Kristen MS;
Dammer, Eric B;
Seyfried, Nicholas T.;
Muzumdar, Sukalp;
Gillis, Jesse;
Robson, Paul;
Zhang, Jigang;
Hohman, Timothy J.;
Philip, Vivek M.;
Menon, Vilas

Publication type:

Article

Single amino acid change in the receptor binding domain of mouse APOE results in altered protein dynamics and worsened AD‐related cognitive impairment.

Published in:

Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2022, v. 18, n. 4, p. 1, doi. 10.1002/alz.067225

By:

Kaczorowski, Catherine C.;
Singh, Surjeet;
Kaur, Harpreet;
Hadad, Niran;
Telpoukhovskaia, Maria;
Zhang, Jigang;
Philip, Vivek M.;
O'Connell, Kristen MS;
Levine, Zachary;
Dunn, Amy R

Publication type:

Article

Identification of transcriptional signatures of cognitive resilience using single nucleus RNA sequencing.

Published in:

Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2022, v. 18, n. 3, p. 1, doi. 10.1002/alz.065947

By:

Hadad, Niran;
Telpoukhovskaia, Maria;
Zhang, Jigang;
Samuels, Michael;
Robson, Paul;
Philip, Vivek M.;
Kaczorowski, Catherine C.

Publication type:

Article

Disentangling the determinants of transposable element expression in cognitive aging and Alzheimer's disease deficits using the AD‐BXD mouse population.

Published in:

Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2021, v. 17, n. 3, p. 1, doi. 10.1002/alz.053048

By:

Philip, Vivek M.;
Anderson, David;
Ramirez, Paulino;
Frost, Bess;
Kaczorowski, Catherine C.

Publication type:

Article

APOE variant in the receptor binding domain confers cognitive resilience to familial Alzheimer's mutations and cell‐type specific gene expression changes in the hippocampus.

Published in:

Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2021, v. 17, n. 3, p. 1, doi. 10.1002/alz.051794

By:

King, Jillian L.;
Anderson, David;
Zhang, Jigang;
Telpoukhovskaia, Maria;
Hadad, Niran;
Dunn, Amy R;
Dumitrescu, Logan;
Hohman, Timothy J.;
O'Connell, Kristen MS;
Philip, Vivek M.;
Kaczorowski, Catherine C.

Publication type:

Article

Molecular Identification of Collagen 17a1 as a Major Genetic Modifier of Laminin Gamma 2 Mutation-Induced Junctional Epidermolysis Bullosa in Mice.

Published in:

PLoS Genetics, 2014, v. 10, n. 2, p. 1, doi. 10.1371/journal.pgen.1004068

By:

Sproule, Thomas J.;
Bubier, Jason A.;
Grandi, Fiorella C.;
Sun, Victor Z.;
Philip, Vivek M.;
McPhee, Caroline G.;
Adkins, Elisabeth B.;
Sundberg, John P.;
Roopenian, Derry C.

Publication type:

Article

A Microbe Associated with Sleep Revealed by a Novel Systems Genetic Analysis of the Microbiome in Collaborative Cross Mice.

Published in:

Genetics, 2020, v. 214, n. 3, p. 719, doi. 10.1534/genetics.119.303013

By:

Bubier, Jason A.;
Philip, Vivek M.;
Quince, Christopher;
Campbell, James;
Yanjiao Zhou;
Vishnivetskaya, Tatiana;
Duvvuru, Suman;
Hageman Blair, Rachel;
Ndukum, Juliet;
Donohue, Kevin D.;
Foster, Carmen M.;
Mellert, David J.;
Weinstock, George;
Culiat, Cymbeline T.;
O'Hara, Bruce F.;
Palumbo, Anthony V.;
Podar, Mircea;
Chesler, Elissa J.

Publication type:

Article

A Bayesian Framework for Generalized Linear Mixed Modeling Identifies New Candidate Loci for Late-Onset Alzheimer's Disease.

Published in:

Genetics, 2018, v. 209, n. 1, p. 51, doi. 10.1534/genetics.117.300673

By:

Xulong Wang;
Philip, Vivek M.;
Ananda, Guruprasad;
White, Charles C.;
Malhotra, Ankit;
Michalski, Paul J.;
Murthy Karuturi, Krishna R.;
Chintalapudi, Sumana R.;
Acklin, Casey;
Sasner, Michael;
Bennett, David A.;
De Jager, Philip L.;
Howell, Gareth R.;
Carter, Gregory W.

Publication type:

Article

Genome-wide association for testis weight in the diversity outbred mouse population.

Published in:

Mammalian Genome, 2018, v. 29, n. 5/6, p. 310, doi. 10.1007/s00335-018-9745-8

By:

Yuan, Joshua T.;
Gatti, Daniel M.;
Philip, Vivek M.;
Kasparek, Steven;
Kreuzman, Andrew M.;
Mansky, Benjamin;
Sharif, Kayvon;
Taterra, Dominik;
Taylor, Walter M.;
Thomas, Mary;
Ward, Jeremy O.;
Holmes, Andrew;
Chesler, Elissa J.;
Parker, Clarissa C.

Publication type:

Article

The Collaborative Cross at Oak Ridge National Laboratory: developing a powerful resource for systems genetics.

Published in:

Mammalian Genome, 2008, v. 19, n. 6, p. 382, doi. 10.1007/s00335-008-9135-8

By:

Chesler, Elissa J.;
Miller, Darla R.;
Branstetter, Lisa R.;
Galloway, Leslie D.;
Jackson, Barbara L.;
Philip, Vivek M.;
Voy, Brynn H.;
Culiat, Cymbeline T.;
Threadgill, David W.;
Williams, Robert W.;
Churchill, Gary A.;
Johnson, Dabney K.;
Manly, Kenneth F.

Publication type:

Article

Minor genomic differences between related B6 and B10 mice affect severity of schistosome infection by governing the mode of dendritic cell activation.

Published in:

European Journal of Immunology, 2015, v. 45, n. 8, p. 2312, doi. 10.1002/eji.201545547

By:

Smith, Patrick M.;
Sproule, Thomas J.;
Philip, Vivek M.;
Roopenian, Derry C.;
Stadecker, Miguel J.

Publication type:

Article