Works by Pfuhl, Mark

Results: 23

Aurora-A-Dependent Control of TACC3 Influences the Rate of Mitotic Spindle Assembly.

Published in:

PLoS Genetics, 2015, v. 11, n. 7, p. 1, doi. 10.1371/journal.pgen.1005345

By:

Burgess, Selena G.;
Peset, Isabel;
Joseph, Nimesh;
Cavazza, Tommaso;
Vernos, Isabelle;
Pfuhl, Mark;
Gergely, Fanni;
Bayliss, Richard

Publication type:

Article

Discovery of novel cardiac troponin activators using fluorescence polarization-based high throughput screening assays.

Published in:

Scientific Reports, 2023, v. 13, n. 1, p. 1, doi. 10.1038/s41598-023-32476-w

By:

Parijat, Priyanka;
Ponnam, Saraswathi;
Attili, Seetharamaiah;
Campbell, Kenneth S.;
El-Mezgueldi, Mohammed;
Pfuhl, Mark;
Kampourakis, Thomas

Publication type:

Article

Mitotic spindle association of TACC3 requires Aurora‐A‐dependent stabilization of a cryptic α‐helix.

Published in:

EMBO Journal, 2018, v. 37, n. 8, p. 1, doi. 10.15252/embj.201797902

By:

Burgess, Selena G.;
Mukherjee, Manjeet;
Sabir, Sarah;
Joseph, Nimesh;
Gutiérrez‐Caballero, Cristina;
Richards, Mark W.;
Huguenin‐Dezot, Nicolas;
Chin, Jason W.;
Kennedy, Eileen J.;
Pfuhl, Mark;
Royle, Stephen J.;
Gergely, Fanni;
Bayliss, Richard

Publication type:

Article

Structure, interactions and function of the N-terminus of cardiac myosin binding protein C (MyBP-C): who does what, with what, and to whom?

Published in:

Journal of Muscle Research & Cell Motility, 2012, v. 33, n. 2, p. 83, doi. 10.1007/s10974-012-9291-z

By:

Pfuhl, Mark;
Gautel, Mathias

Publication type:

Article

Fragment-based screening identifies molecules targeting the substrate-binding ankyrin repeat domains of tankyrase.

Published in:

Scientific Reports, 2019, v. 9, n. 1, p. 1, doi. 10.1038/s41598-019-55240-5

By:

Pollock, Katie;
Liu, Manjuan;
Zaleska, Mariola;
Meniconi, Mirco;
Pfuhl, Mark;
Collins, Ian;
Guettler, Sebastian

Publication type:

Article

A structural and functional dissection of the cardiac stress response factor MS1.

Published in:

Proteins, 2012, v. 80, n. 2, p. 398, doi. 10.1002/prot.23201

By:

Fogl, Claudia;
Puckey, Loretto;
Hinssen, Ulrike;
Zaleska, Mariola;
El-Mezgueldi, Mohammed;
Croasdale, Rebecca;
Bowman, Andrew;
Matsukawa, Akira;
Samani, Nilesh J.;
Savva, Renos;
Pfuhl, Mark

Publication type:

Article

Structural characterization and inhibition of the interaction between ch-TOG and TACC3.

Published in:

Journal of Cell Biology, 2025, v. 224, n. 6, p. 1, doi. 10.1083/jcb.202407002

By:

Shelford, James;
Burgess, Selena G.;
Rostkova, Elena;
Richards, Mark W.;
Larocque, Gabrielle;
Sampson, Josephina;
Tiede, Christian;
Fielding, Alistair J.;
Daviter, Tina;
Tomlinson, Darren C.;
Calabrese, Antonio N.;
Pfuhl, Mark;
Bayliss, Richard;
Royle, Stephen J.

Publication type:

Article

Coordination of adjacent domains mediates TACC3--ch-TOG--clathrin assembly and mitotic spindle binding.

Published in:

Journal of Cell Biology, 2013, v. 202, n. 3, p. 463, doi. 10.1083/jcb.201211127

By:

Hood, Fiona E.;
Williams, Samantha J.;
Burgess, Selena G.;
Richards, Mark W.;
Roth, Daniel;
Straube, Anne;
Pfuhl, Mark;
Bayliss, Richard;
Royle, Stephen J.

Publication type:

Article

Controlling the dynamics of the Nek2 leucine zipper by engineering of “kinetic” disulphide bonds.

Published in:

PLoS ONE, 2019, v. 14, n. 2, p. 1, doi. 10.1371/journal.pone.0210352

By:

Gutmans, Daniel S.;
Whittaker, Sara B-M;
Asiani, Karishma;
Atkinson, R. Andrew;
Oregioni, Alain;
Pfuhl, Mark

Publication type:

Article

Making sense of missense variants in TTN-related congenital myopathies.

Published in:

Acta Neuropathologica, 2021, v. 141, n. 3, p. 431, doi. 10.1007/s00401-020-02257-0

By:

Rees, Martin;
Nikoopour, Roksana;
Fukuzawa, Atsushi;
Kho, Ay Lin;
Fernandez-Garcia, Miguel A.;
Wraige, Elizabeth;
Bodi, Istvan;
Deshpande, Charu;
Özdemir, Özkan;
Daimagüler, Hülya-Sevcan;
Pfuhl, Mark;
Holt, Mark;
Brandmeier, Birgit;
Grover, Sarah;
Fluss, Joël;
Longman, Cheryl;
Farrugia, Maria Elena;
Matthews, Emma;
Hanna, Michael;
Muntoni, Francesco

Publication type:

Article

Correction: Differential effects of mutations of POPDC proteins on heteromeric interaction and membrane trafficking.

Published in:

2023

By:

Swan, Alexander H.;
Schindler, Roland F. R.;
Savarese, Marco;
Mayer, Isabelle;
Rinné, Susanne;
Bleser, Felix;
Schänzer, Anne;
Hahn, Andreas;
Sabatelli, Mario;
Perna, Francesco;
Chapman, Kathryn;
Pfuhl, Mark;
Spivey, Alan C.;
Decher, Niels;
Udd, Bjarne;
Tasca, Giorgio;
Brand, Thomas

Publication type:

Correction Notice

Differential effects of mutations of POPDC proteins on heteromeric interaction and membrane trafficking.

Published in:

Acta Neuropathologica Communications, 2023, v. 11, n. 1, p. 1, doi. 10.1186/s40478-022-01501-w

By:

Swan, Alexander H.;
Schindler, Roland F. R.;
Savarese, Marco;
Mayer, Isabelle;
Rinné, Susanne;
Bleser, Felix;
Schänzer, Anne;
Hahn, Andreas;
Sabatelli, Mario;
Perna, Francesco;
Chapman, Kathryn;
Pfuhl, Mark;
Spivey, Alan C.;
Decher, Niels;
Udd, Bjarne;
Tasca, Giorgio;
Brand, Thomas

Publication type:

Article

Development of a Potential Yeast-Based Vaccine Platform for Theileria parva Infection in Cattle.

Published in:

Frontiers in Immunology, 2021, v. 12, p. 1, doi. 10.3389/fimmu.2021.674484

By:

Goh, Shan;
Kolakowski, Jeannine;
Holder, Angela;
Pfuhl, Mark;
Ngugi, Daniel;
Ballingall, Keith;
Tombacz, Kata;
Werling, Dirk

Publication type:

Article

Obscurin Rho GEF domains are phosphorylated by MST-family kinases but do not exhibit nucleotide exchange factor activity towards Rho GTPases in vitro.

Published in:

PLoS ONE, 2023, v. 18, n. 4, p. 1, doi. 10.1371/journal.pone.0284453

By:

Koch, Daniel;
Kho, Ay Lin;
Fukuzawa, Atsushi;
Alexandrovich, Alexander;
Vanaanen, Kutti J.;
Beavil, Andrew;
Pfuhl, Mark;
Rees, Martin;
Gautel, Mathias

Publication type:

Article

The binding stoichiometry of CIN85 SH3 domain A and Cbl-b.

Published in:

2008

By:

Ababou, Abdessamad;
Pfuhl, Mark;
Ladbury, John E.

Publication type:

Letter

The Cardiac Stress Response Factor Ms1 Can Bind to DNA and Has a Function in the Nucleus.

Published in:

PLoS ONE, 2015, v. 10, n. 12, p. 1, doi. 10.1371/journal.pone.0144614

By:

Zaleska, Mariola;
Fogl, Claudia;
Kho, Ay Lin;
Ababou, Abdessamad;
Ehler, Elisabeth;
Pfuhl, Mark

Publication type:

Article

Large-Scale Modelling of the Divergent Spectrin Repeats in Nesprins: Giant Modular Proteins

Published in:

PLoS ONE, 2013, v. 8, n. 5, p. 1, doi. 10.1371/journal.pone.0063633

By:

Autore, Flavia;
Pfuhl, Mark;
Quan, Xueping;
Williams, Aisling;
Roberts, Roland G.;
Shanahan, Catherine M.;
Fraternali, Franca

Publication type:

Article

Letter to the Editor: Sequence Specific Assignment of Domain C1 of the N-terminal Myosin-binding Site of Human Cardiac Myosin Binding Protein C (MyBP-C).

Published in:

Journal of Biomolecular NMR, 2004, v. 29, n. 3, p. 431, doi. 10.1023/B:JNMR.0000032510.03606.63

By:

Ababou, Abdessamad;
Zhou, Lihong;
Gautel, Mathias;
Pfuhl, Mark

Publication type:

Article

Letter to the Editor: Sequence specific resonance assignment of the central domain of cardiac Myosin Binding Protein C (MyBP-C).

Published in:

Journal of Biomolecular NMR, 2002, v. 22, n. 2, p. 199, doi. 10.1023/A:1014248522896

By:

Idowu, Seraphina.M.;
Gautel, Mathias;
Pfuhl, Mark

Publication type:

Article

Solution NMR assignment of the ARC4 domain of human tankyrase 2.

Published in:

Biomolecular NMR Assignments, 2019, v. 13, n. 1, p. 255, doi. 10.1007/s12104-019-09887-w

By:

Zaleska, Mariola;
Pollock, Katie;
Collins, Ian;
Guettler, Sebastian;
Pfuhl, Mark

Publication type:

Article

Solution NMR assignment of the C-terminal domain of human chTOG.

Published in:

Biomolecular NMR Assignments, 2018, v. 12, n. 2, p. 221, doi. 10.1007/s12104-018-9812-9

By:

Rostkova, Elena;
Burgess, Selena G.;
Bayliss, Richard;
Pfuhl, Mark

Publication type:

Article

Solution NMR assignment of the cryptic sixth TOG domain of mini spindles.

Published in:

Biomolecular NMR Assignments, 2015, v. 9, n. 2, p. 411, doi. 10.1007/s12104-015-9620-4

By:

Burgess, Selena;
Bayliss, Richard;
Pfuhl, Mark

Publication type:

Article

Solution NMR assignment of the heavy chain complex of the human cardiac myosin regulatory light chain.

Published in:

Biomolecular NMR Assignments, 2015, v. 9, n. 1, p. 51, doi. 10.1007/s12104-014-9543-5

By:

Rostkova, Elena;
Gautel, Mathias;
Pfuhl, Mark

Publication type:

Article