Works by Pflugfelder, Stephen C.

Results: 67

Effects of azithromycin on gene expression profiles of proinflammatory and anti-inflammatory mediators in the eyelid margin and conjunctiva of patients with meibomian gland disease.

Published in:

2015

By:

Lili Zhang;
Zhitao Su;
Zongduan Zhang;
Jing Lin;
De-Quan Li;
Pflugfelder, Stephen C.;
Zhang, Lili;
Su, Zhitao;
Zhang, Zongduan;
Lin, Jing;
Li, De-Quan

Publication type:

journal article

Study design and baseline findings from the progression of ocular findings (PROOF) natural history study of dry eye.

Published in:

BMC Ophthalmology, 2017, v. 17, p. 1, doi. 10.1186/s12886-017-0646-5

By:

McDonnell, Peter J.;
Pflugfelder, Stephen C.;
Stern, Michael E.;
Hardten, David R.;
Conway, Taryn;
Villanueva, Linda;
Hollander, David A.

Publication type:

Article

MMP-8 Is Critical for Dexamethasone Therapy in Alkali-Burned Corneas Under Dry Eye Conditions.

Published in:

Journal of Cellular Physiology, 2016, v. 231, n. 11, p. 2506, doi. 10.1002/jcp.25364

By:

Bian, Fang;
Wang, Changjun;
Tukler ‐ Henriksson, Johanna;
Pflugfelder, Stephen C.;
Camodeca, Caterina;
Nuti, Elisa;
Rossello, Armando;
Li, De ‐ Quan;
de Paiva, Cintia S.

Publication type:

Article

Potential localization of putative stem/progenitor cells in human bulbar conjunctival epithelium.

Published in:

Journal of Cellular Physiology, 2010, v. 225, n. 1, p. 180, doi. 10.1002/jcp.22215

By:

HONG QI;
XIAOFEN ZHENG;
XIAOYONG YUAN;
PFLUGFELDER, STEPHEN C.;
DE-QUAN LI

Publication type:

Article

Induction of Th17 differentiation by corneal epithelial-derived cytokines.

Published in:

Journal of Cellular Physiology, 2010, v. 222, n. 1, p. 95, doi. 10.1002/jcp.21926

By:

XIAOFEN ZHENG;
FANG BIAN;
PING MA;
DE PAIVA, CINTIA S.;
STERN, MICHAEL;
PFLUGFELDER, STEPHEN C.;
DE-QUAN LI

Publication type:

Article

Growth Factor Supplementation: A New Paradigm in Ocular Surface Disease Management.

Published in:

Optometry Times, 2024, v. 16, n. 9, p. 27

By:

Chan, Clara C.;
Coroneo, Minas;
Hamrah, Pedram;
Perez, Victor L.;
Pflugfelder, Stephen C.

Publication type:

Article

Long-term outcomes of ciliary sulcus versus capsular bag fixation of intraocular lenses in children: An ultrasound biomicroscopy study.

Published in:

PLoS ONE, 2017, v. 12, n. 3, p. 1, doi. 10.1371/journal.pone.0172979

By:

Zhao, Yun-e;
Gong, Xian-hui;
Zhu, Xue-ning;
Li, He-ming;
Tu, Meng-jun;
Coursey, Terry G.;
Pflugfelder, Stephen C.;
Gu, Feng;
Chen, Ding

Publication type:

Article

The utility of software-detected non-invasive tear break-up in comparison to fluorescein tear break-up measurements.

Published in:

Frontiers in Medicine, 2024, p. 1, doi. 10.3389/fmed.2024.1351013

By:

Pflugfelder, Stephen C.;
Yasushi Kikukawa;
Shin Tanaka;
Takuya Kosugi

Publication type:

Article

Single cell analysis of short-term dry eye induced changes in cornea immune cell populations.

Published in:

Frontiers in Medicine, 2024, p. 1, doi. 10.3389/fmed.2024.1362336

By:

Alam, Jehan;
Yaman, Ebru;
Villalba Silva, Gerda Cristal;
Rui Chen;
de Paiva, Cintia S.;
Stepp, Mary Ann;
Pflugfelder, Stephen C.

Publication type:

Article

Single cell analysis of short-term dry eye induced changes in cornea immune cell populations.

Published in:

Frontiers in Medicine, 2024, p. 1, doi. 10.3389/fmed.2024.1362336

By:

Alam, Jehan;
Yaman, Ebru;
Silva, Gerda Cristal Villalba;
Rui Chen;
de Paiva, Cinita S.;
Stepp, Mary Ann;
Pflugfelder, Stephen C.

Publication type:

Article

Recognition, Treatment, and Prevention of Endophthalmitis: Appendix.

Published in:

Seminars in Ophthalmology, 1989, v. 4, n. 2, p. 69, doi. 10.3109/08820538909060138

By:

Flynn, Harry W.;
Pflugfelder, Stephen C.;
Culbertson, William W.;
Davis, Janet L.

Publication type:

Article

Study design and baseline findings from the progression of ocular findings (PROOF) natural history study of dry eye.

Published in:

2017

By:

McDonnell, Peter J.;
Pflugfelder, Stephen C.;
Stern, Michael E.;
Hardten, David R.;
Conway, Taryn;
Villanueva, Linda;
Hollander, David A.

Publication type:

journal article

Human Corneal Epithelial Cells Produce Antimicrobial Peptides LL-37 and β-Defensins in Response to Heat-Killed Candida albicans.

Published in:

Ophthalmic Research, 2014, v. 51, n. 4, p. 179, doi. 10.1159/000357977

By:

Hua, Xia;
Yuan, Xiaoyong;
Tang, Xin;
Li, Zhijie;
Pflugfelder, Stephen C.;
Li, De-Quan

Publication type:

Article

Author Correction: Gut-derived butyrate suppresses ocular surface inflammation.

Published in:

2022

By:

Schaefer, Laura;
Hernandez, Humberto;
Coats, Rosalind A.;
Yu, Zhiyuan;
Pflugfelder, Stephen C.;
Britton, Robert A.;
de Paiva, Cintia S.

Publication type:

Correction Notice

Gut-derived butyrate suppresses ocular surface inflammation.

Published in:

Scientific Reports, 2022, v. 12, n. 1, p. 1, doi. 10.1038/s41598-022-08442-3

By:

Schaefer, Laura;
Hernandez, Humberto;
Coats, Rosalind A.;
Yu, Zhiyuan;
Pflugfelder, Stephen C.;
Britton, Robert A.;
de Paiva, Cintia

Publication type:

Article

Gut-derived butyrate suppresses ocular surface inflammation.

Published in:

Scientific Reports, 2022, v. 12, n. 1, p. 1, doi. 10.1038/s41598-022-08442-3

By:

Schaefer, Laura;
Hernandez, Humberto;
Coats, Rosalind A.;
Yu, Zhiyuan;
Pflugfelder, Stephen C.;
Britton, Robert A.;
de Paiva, Cintia

Publication type:

Article

Quantitative assessment of botulinum toxin injection on blink rate in blepharospasm.

Published in:

Orbit, 2023, v. 42, n. 6, p. 571, doi. 10.1080/01676830.2022.2151628

By:

Yazdanpanah, Ghasem;
Yen, Michael T.;
Pflugfelder, Stephen C.

Publication type:

Article

Goblet cell-produced retinoic acid suppresses CD86 expression and IL-12 production in bone marrow-derived cells.

Published in:

International Immunology, 2018, v. 30, n. 10, p. 457, doi. 10.1093/intimm/dxy045

By:

Xiao, Yangyan;
Paiva, Cintia S de;
Yu, Zhiyuan;
Souza, Rodrigo G de;
Li, De-Quan;
Pflugfelder, Stephen C

Publication type:

Article

Effects of l-Carnitine, Erythritol and Betaine on Pro-inflammatory Markers in Primary Human Corneal Epithelial Cells Exposed to Hyperosmotic Stress.

Published in:

Current Eye Research, 2015, v. 40, n. 7, p. 657, doi. 10.3109/02713683.2014.957776

By:

Hua, Xia;
Su, Zhitao;
Deng, Ruzhi;
Lin, Jing;
Li, De-Quan;
Pflugfelder, Stephen C.

Publication type:

Article

In Vivo Confocal Microscopy of the Ocular Surface: From Bench to Bedside.

Published in:

Current Eye Research, 2014, v. 39, n. 3, p. 213, doi. 10.3109/02713683.2013.842592

By:

Villani, Edoardo;
Baudouin, Christophe;
Efron, Nathan;
Hamrah, Pedram;
Kojima, Takashi;
Patel, Sanjay V.;
Pflugfelder, Stephen C.;
Zhivov, Andrey;
Dogru, Murat

Publication type:

Article

Altered cytokine balance in the tear fluid and conjunctiva of patientswith Sjögren's syndrome keratoconjunctivitis sicca.

Published in:

Current Eye Research, 1999, v. 19, n. 3, p. 201, doi. 10.1076/ceyr.19.3.201.5309

By:

Pflugfelder, Stephen C.;
Jones, David;
Ji, Zhonghua;
Afonso, Adolfo;
Monroy, Dagoberto

Publication type:

Article

Clinicians' Corner.

Published in:

2014

By:

Pflugfelder, Stephen C.;
Tauber, Joseph

Publication type:

Question & Answer

Delphi Panel Consensus Regarding Current Clinical Practice Management Options for Demodex blepharitis.

Published in:

Clinical Ophthalmology, 2023, v. 17, p. 667, doi. 10.2147/OPTH.S399989

By:

Farid, Marjan;
Ayres, Brandon D;
Donnenfeld, Eric;
Gaddie, Ian Benjamin;
Gupta, Preeya K;
Holland, Edward;
Lindstrom, Richard;
Pflugfelder, Stephen C;
Karpecki, Paul M;
Nichols, Kelly K;
Starr, Christopher E;
Yeu, Elizabeth

Publication type:

Article

Challenges in the clinical measurement of ocular surface disease in glaucoma patients.

Published in:

Clinical Ophthalmology, 2011, v. 5, p. 1575, doi. 10.2147/OPTH.S24410

By:

Pflugfelder, Stephen C.;
Baudouin, Christophe

Publication type:

Article

Non-invasive and objective tear film breakup detection on interference color images using convolutional neural networks.

Published in:

PLoS ONE, 2023, v. 18, n. 3, p. 1, doi. 10.1371/journal.pone.0282973

By:

Kikukawa, Yasushi;
Tanaka, Shin;
Kosugi, Takuya;
Pflugfelder, Stephen C.

Publication type:

Article

Calcineurin Inhibitor Voclosporin Preserves Corneal Barrier and Conjunctival Goblet Cells in Experimental Dry Eye.

Published in:

2020

By:

Alam, Jehan;
de Souza, Rodrigo G.;
Yu, Zhiyuan;
Stern, Michael E.;
de Paiva, Cintia S.;
Pflugfelder, Stephen C.

Publication type:

journal article

Suppression of Th1-Mediated Keratoconjunctivitis Sicca by Lifitegrast.

Published in:

2018

By:

Guimaraes de Souza, Rodrigo;
Yu, Zhiyuan;
Stern, Michael E.;
Pflugfelder, Stephen C.;
de Paiva, Cintia S.

Publication type:

journal article

LFA-1/ICAM-1 Interaction as a Therapeutic Target in Dry Eye Disease.

Published in:

2017

By:

Pflugfelder, Stephen C.;
Stern, Michael;
Zhang, Steven;
Shojaei, Amir

Publication type:

journal article

Mucosal environmental sensors in the pathogenesis of dry eye.

Published in:

Expert Review of Clinical Immunology, 2014, v. 10, n. 9, p. 1137, doi. 10.1586/1744666X.2014.944163

By:

Pflugfelder, Stephen C;
Stern, Michael E

Publication type:

Article

What causes dryness in Sjögren's syndrome patients and how can it be targeted?

Published in:

Expert Review of Clinical Immunology, 2014, v. 10, n. 4, p. 425, doi. 10.1586/1744666X.2014.891440

By:

Pflugfelder, Stephen C

Publication type:

Article

Comparison of Efficacy and Inflammatory Response to Thermoconjunctivoplasty Performed with Cautery or Pulsed 1460 nm Laser.

Published in:

International Journal of Molecular Sciences, 2023, v. 24, n. 6, p. 5740, doi. 10.3390/ijms24065740

By:

de Souza, Rodrigo Guimaraes;
Huang, David;
Prahl, Scott;
Nakhleh, Lauren;
Pflugfelder, Stephen C.

Publication type:

Article

Characterization of Type I Interferon-Associated Chemokines and Cytokines in Lacrimal Glands of Nonobese Diabetic Mice.

Published in:

International Journal of Molecular Sciences, 2021, v. 22, n. 7, p. 3767, doi. 10.3390/ijms22073767

By:

Allred, Merri-Grace;
Chimenti, Michael S.;
Ciecko, Ashley E.;
Chen, Yi-Guang;
Lieberman, Scott M.;
De Paiva, Cintia S.;
Pflugfelder, Stephen C.

Publication type:

Article

Blue Light Induces Impaired Autophagy through Nucleotide-Binding Oligomerization Domain 2 Activation on the Mouse Ocular Surface.

Published in:

International Journal of Molecular Sciences, 2021, v. 22, n. 4, p. 2015, doi. 10.3390/ijms22042015

By:

Li, Ying;
Jin, Rujun;
Li, Lan;
Choi, Ji Suk;
Kim, Jonghwa;
Yoon, Hyeon Jeong;
Park, Jong Hwan;
Yoon, Kyung Chul;
De Paiva, Cintia S.;
Pflugfelder, Stephen C.;
Holland, Martin J.

Publication type:

Article

Retinoid Regulation of Ocular Surface Innate Inflammation.

Published in:

International Journal of Molecular Sciences, 2021, v. 22, n. 3, p. 1092, doi. 10.3390/ijms22031092

By:

Alam, Jehan;
Yu, Zhiyuan;
de Paiva, Cintia S.;
Pflugfelder, Stephen C.;
Kurihara, Toshihide

Publication type:

Article

Defining Dry Eye from a Clinical Perspective.

Published in:

International Journal of Molecular Sciences, 2020, v. 21, n. 23, p. 9271, doi. 10.3390/ijms21239271

By:

Tsubota, Kazuo;
Pflugfelder, Stephen C.;
Liu, Zuguo;
Baudouin, Christophe;
Kim, Hyo Myung;
Messmer, Elisabeth M.;
Kruse, Friedrich;
Liang, Lingyi;
Carreno-Galeano, Jimena Tatiana;
Rolando, Maurizio;
Yokoi, Norihiko;
Kinoshita, Shigeru;
Dana, Reza

Publication type:

Article

Mechanisms of Disease in Sjögren Syndrome—New Developments and Directions.

Published in:

International Journal of Molecular Sciences, 2020, v. 21, n. 2, p. 1, doi. 10.3390/ijms21020650

By:

de Paiva, Cintia S.;
Pflugfelder, Stephen C.

Publication type:

Article

Reduced Corneal Innervation in the CD25 Null Model of Sjögren Syndrome †.

Published in:

International Journal of Molecular Sciences, 2018, v. 19, n. 12, p. 3821, doi. 10.3390/ijms19123821

By:

Stepp, Mary Ann;
Pal-Ghosh, Sonali;
Tadvalkar, Gauri;
Williams, Alexa R.;
Pflugfelder, Stephen C.;
de Paiva, Cintia S.

Publication type:

Article

Severity of Sjögren's Syndrome Keratoconjunctivitis Sicca Increases with Increased Percentage of Conjunctival Antigen-Presenting Cells.

Published in:

International Journal of Molecular Sciences, 2018, v. 19, n. 9, p. 2760, doi. 10.3390/ijms19092760

By:

Pflugfelder, Stephen C.;
Bian, Fang;
Gumus, Koray;
Farley, William;
Stern, Michael E.;
De Paiva, Cintia S.

Publication type:

Article

Sjögren-Like Lacrimal Keratoconjunctivitis in Germ-Free Mice.

Published in:

International Journal of Molecular Sciences, 2018, v. 19, n. 2, p. 565, doi. 10.3390/ijms19020565

By:

Wang, Changjun;
Zaheer, Mahira;
Bian, Fang;
Quach, Darin;
Swennes, Alton G.;
Britton, Robert A.;
Pflugfelder, Stephen C.;
de Paiva, Cintia S.

Publication type:

Article

Goblet Cells Contribute to Ocular Surface Immune Tolerance—Implications for Dry Eye Disease.

Published in:

International Journal of Molecular Sciences, 2017, v. 18, n. 5, p. 978, doi. 10.3390/ijms18050978

By:

Barbosa, Flavia L.;
Yangyan Xiao;
Fang Bian;
Coursey, Terry G.;
Byung Yi Ko;
Clevers, Hans;
de Paiva, Cintia S.;
Pflugfelder, Stephen C.

Publication type:

Article

Inhibition of NLRP3 Inflammasome Pathway by Butyrate Improves Corneal Wound Healing in Corneal Alkali Burn.

Published in:

International Journal of Molecular Sciences, 2017, v. 18, n. 3, p. 562, doi. 10.3390/ijms18030562

By:

Fang Bian;
Yangyan Xiao;
Zaheer, Mahira;
Volpe, Eugene A.;
Pflugfelder, Stephen C.;
De-Quan Li;
De Paiva, Cintia S.

Publication type:

Article

Dry Eye as a Mucosal Autoimmune Disease.

Published in:

International Reviews of Immunology, 2013, v. 32, n. 1, p. 19, doi. 10.3109/08830185.2012.748052

By:

Stern, Michael E.;
Schaumburg, Chris S.;
Pflugfelder, Stephen C.

Publication type:

Article

Pollen/TLR4 Innate Immunity Signaling Initiates IL-33/ST2/Th2 Pathways in Allergic Inflammation.

Published in:

Scientific Reports, 2016, p. 36150, doi. 10.1038/srep36150

By:

Li, Jin;
Zhang, Lili;
Chen, Xin;
Chen, Ding;
Hua, Xia;
Bian, Fang;
Deng, Ruzhi;
Lu, Fan;
Li, Zhijie;
Pflugfelder, Stephen C.;
Li, De-Quan

Publication type:

Article

Altered Mucosal Microbiome Diversity and Disease Severity in Sjögren Syndrome.

Published in:

Scientific Reports, 2016, p. 23561, doi. 10.1038/srep23561

By:

de Paiva, Cintia S.;
Jones, Dan B.;
Stern, Michael E.;
Bian, Fang;
Moore, Quianta L.;
Corbiere, Shani;
Streckfus, Charles F.;
Hutchinson, Diane S.;
Ajami, Nadim J.;
Petrosino, Joseph F.;
Pflugfelder, Stephen C.

Publication type:

Article

Blueberry Component Pterostilbene Protects Corneal Epithelial Cells from Inflammation via Anti-oxidative Pathway.

Published in:

Scientific Reports, 2016, p. 19408, doi. 10.1038/srep19408

By:

Li, Jin;
Ruzhi Deng;
Hua, Xia;
Zhang, Lili;
Lu, Fan;
Coursey, Terry G.;
Pflugfelder, Stephen C.;
Li, De-Quan

Publication type:

Article

Ectoine, from a Natural Bacteria Protectant to a New Treatment of Dry Eye Disease.

Published in:

Pharmaceutics, 2024, v. 16, n. 2, p. 236, doi. 10.3390/pharmaceutics16020236

By:

Chen, Xin;
Lin, Na;
Li, Jin-Miao;
Liu, Haixia;
Abu-Romman, Anmar;
Yaman, Ebru;
Bian, Fang;
de Paiva, Cintia S.;
Pflugfelder, Stephen C.;
Li, De-Quan

Publication type:

Article

Clusterin Seals the Ocular Surface Barrier in Mouse Dry Eye.

Published in:

PLoS ONE, 2015, v. 10, n. 9, p. 1, doi. 10.1371/journal.pone.0138958

By:

Bauskar, Aditi;
Mack, Wendy J.;
Mauris, Jerome;
Argüeso, Pablo;
Heur, Martin;
Nagel, Barbara A.;
Kolar, Grant R.;
Gleave, Martin E.;
Nakamura, Takahiro;
Kinoshita, Shigeru;
Moradian-Oldak, Janet;
Panjwani, Noorjahan;
Pflugfelder, Stephen C.;
Wilson, Mark R.;
Fini, M. Elizabeth;
Jeong, Shinwu

Publication type:

Article

A Novel Innate Response of Human Corneal Epithelium to Heat-killed Candida albicans by Producing Peptidoglycan Recognition Proteins.

Published in:

PLoS ONE, 2015, v. 10, n. 6, p. 1, doi. 10.1371/journal.pone.0128039

By:

Hua, Xia;
Yuan, Xiaoyong;
Li, Zhijie;
Coursey, Terry G.;
Pflugfelder, Stephen C.;
Li, De-Quan

Publication type:

Article

Oxidative Stress Markers Induced by Hyperosmolarity in Primary Human Corneal Epithelial Cells.

Published in:

PLoS ONE, 2015, v. 10, n. 5, p. 1, doi. 10.1371/journal.pone.0126561

By:

Deng, Ruzhi;
Hua, Xia;
Li, Jin;
Chi, Wei;
Zhang, Zongduan;
Lu, Fan;
Zhang, Lili;
Pflugfelder, Stephen C.;
Li, De-Quan

Publication type:

Article

Unique Expression Pattern and Functional Role of Periostin in Human Limbal Stem Cells.

Published in:

PLoS ONE, 2015, v. 10, n. 2, p. 1, doi. 10.1371/journal.pone.0117139

By:

Qu, Yangluowa;
Chi, Wei;
Hua, Xia;
Deng, Ruzhi;
Li, Jin;
Liu, Zuguo;
Pflugfelder, Stephen C.;
Li, De-Quan

Publication type:

Article