Works by Pfister, Stefan M.

Results: 174

Experimental Insights and Recommendations for Successfully Performing Cerebral Microdialysis With Hydrophobic Drug Candidates.

Published in:

CTS: Clinical & Translational Science, 2025, v. 18, n. 5, p. 1, doi. 10.1111/cts.70226

By:

Sundheimer, Julia K.;
Benzel, Julia;
Longuespée, Rémi;
Burhenne, Jürgen;
Pfister, Stefan M.;
Maaß, Kendra K.;
Sauter, Max;
Pajtler, Kristian W.

Publication type:

Article

Pediatric meningiomas: A literature review and diagnostic update.

Published in:

Neuro-Oncology Advances, 2023, v. 5, p. i105, doi. 10.1093/noajnl/vdac165

By:

Tauziède-Espariat, Arnault;
Pfister, Stefan M.;
Mawrin, Christian;
Sahm, Felix

Publication type:

Article

Analysis of recurrence probability following radiotherapy in patients with CNS WHO grade 2 meningioma using integrated molecular-morphologic classification.

Published in:

Neuro-Oncology Advances, 2023, v. 5, n. 1, p. 1, doi. 10.1093/noajnl/vdad059

By:

Deng, Maximilian Y;
Hinz, Felix;
Maas, Sybren L N;
Anil, Günes;
Sievers, Philipp;
Conde-Lopez, Cristina;
Lischalk, Jonathan;
Rauh, Sophie;
Eichkorn, Tanja;
Regnery, Sebastian;
Bauer, Lukas;
Held, Thomas;
Meixner, Eva;
Lang, Kristin;
Hörner-Rieber, Juliane;
Herfarth, Klaus;
Jones, David;
Pfister, Stefan M;
Jungk, Christine;
Unterberg, Andreas

Publication type:

Article

Predictive modeling of resistance to SMO inhibition in a patient-derived orthotopic xenograft model of SHH medulloblastoma.

Published in:

Neuro-Oncology Advances, 2022, v. 4, n. 1, p. 1, doi. 10.1093/noajnl/vdac026

By:

Krausert, Sonja;
Brabetz, Sebastian;
Mack, Norman L.;
Schmitt-Hoffner, Felix;
Schwalm, Benjamin;
Peterziel, Heike;
Mangang, Aileen;
Holland-Letz, Tim;
Sieber, Laura;
Korshunov, Andrey;
Oehme, Ina;
Jäger, Natalie;
Witt, Olaf;
Pfister, Stefan M.;
Kool, Marcel

Publication type:

Article

Cancer risk in carriers of TP53 germline variants grouped into different functional categories.

Published in:

JNCI Cancer Spectrum, 2025, v. 9, n. 1, p. 1, doi. 10.1093/jncics/pkaf008

By:

Müntnich, Lucas John;
Dutzmann, Christina M;
Großhennig, Anika;
Härter, Valentina;
Keymling, Myriam;
Mastronuzzi, Angela;
Montellier, Emilie;
Nees, Juliane;
Palmaers, Natalie E;
Penkert, Judith;
Pfister, Stefan M;
Ripperger, Tim;
Schott, Sarah;
Silchmüller, Farina;
Hainaut, Pierre;
Kratz, Christian P

Publication type:

Article

Spatial Dissection of Invasive Front from Tumor Mass Enables Discovery of Novel microRNA Drivers of Glioblastoma Invasion.

Published in:

Advanced Science, 2021, v. 8, n. 23, p. 1, doi. 10.1002/advs.202101923

By:

Huang, Yulun;
Qi, Lin;
Kogiso, Mari;
Du, Yuchen;
Braun, Frank K.;
Zhang, Huiyuan;
Huang, L. Frank;
Xiao, Sophie;
Teo, Wan‐Yee;
Lindsay, Holly;
Zhao, Sibo;
Baxter, Patricia;
Su, Jack M. F.;
Adesina, Adekunle;
Yang, Jianhua;
Brabetz, Sebastian;
Kool, Marcel;
Pfister, Stefan M.;
Chintagumpala, Murali;
Perlaky, Laszlo

Publication type:

Article

Transcriptomic and epigenetic profiling of 'diffuse midline gliomas, H3 K27M-mutant' discriminate two subgroups based on the type of histone H3 mutated and not supratentorial or infratentorial location.

Published in:

Acta Neuropathologica Communications, 2018, v. 6, n. 1, p. N.PAG, doi. 10.1186/s40478-018-0614-1

By:

Castel, David;
Philippe, Cathy;
Kergrohen, Thomas;
Sill, Martin;
Merlevede, Jane;
Barret, Emilie;
Puget, Stéphanie;
Sainte-Rose, Christian;
Kramm, Christof M.;
Jones, Chris;
Varlet, Pascale;
Pfister, Stefan M.;
Grill, Jacques;
Jones, David T. W.;
Debily, Marie-Anne

Publication type:

Article

Proteomic analysis of Medulloblastoma reveals functional biology with translational potential.

Published in:

Acta Neuropathologica Communications, 2018, v. 6, n. 1, p. N.PAG, doi. 10.1186/s40478-018-0548-7

By:

Rivero-Hinojosa, Samuel;
Lau, Ling San;
Stampar, Mojca;
Staal, Jerome;
Zhang, Huizhen;
Gordish-Dressman, Heather;
Northcott, Paul A.;
Pfister, Stefan M.;
Taylor, Michael D.;
Brown, Kristy J.;
Rood, Brian R.

Publication type:

Article

Adamantinomatous and papillary craniopharyngiomas are characterized by distinct epigenomic as well as mutational and transcriptomic profiles.

Published in:

Acta Neuropathologica Communications, 2016, v. 4, p. 1, doi. 10.1186/s40478-016-0287-6

By:

Hölsken, Annett;
Sill, Martin;
Merkle, Jessica;
Schweizer, Leonille;
Buchfelder, Michael;
Flitsch, Jörg;
Fahlbusch, Rudolf;
Metzler, Markus;
Kool, Marcel;
Pfister, Stefan M.;
von Deimling, Andreas;
Capper, David;
Jones, David T. W.;
Buslei, Rolf

Publication type:

Article

Targeting class I histone deacetylase 2 in MYC amplified group 3 medulloblastoma.

Published in:

Acta Neuropathologica Communications, 2015, v. 3, n. 1, p. 121, doi. 10.1186/s40478-015-0201-7

By:

Ecker, Jonas;
Oehme, Ina;
Mazitschek, Ralph;
Korshunov, Andrey;
Kool, Marcel;
Hielscher, Thomas;
Kiss, Judit;
Selt, Florian;
Konrad, Carina;
Lodrini, Marco;
Deubzer, Hedwig E.;
von Deimling, Andreas;
Kulozik, Andreas E.;
Pfister, Stefan M.;
Witt, Olaf;
Milde, Till

Publication type:

Article

Radiotherapy for Recurrent Medulloblastoma in Children and Adolescents: Survival after Re-Irradiation and First-Time Irradiation.

Published in:

Cancers, 2024, v. 16, n. 11, p. 1955, doi. 10.3390/cancers16111955

By:

Adolph, Jonas E.;
Fleischhack, Gudrun;
Tschirner, Sebastian;
Rink, Lydia;
Dittes, Christine;
Mikasch, Ruth;
Dammann, Philipp;
Mynarek, Martin;
Obrecht-Sturm, Denise;
Rutkowski, Stefan;
Bison, Brigitte;
Warmuth-Metz, Monika;
Pietsch, Torsten;
Pfister, Stefan M.;
Pajtler, Kristian W.;
Milde, Till;
Kortmann, Rolf-Dieter;
Dietzsch, Stefan;
Timmermann, Beate;
Tippelt, Stephan

Publication type:

Article

Relapsed Medulloblastoma in Pre-Irradiated Patients: Current Practice for Diagnostics and Treatment.

Published in:

Cancers, 2022, v. 14, n. 1, p. 126, doi. 10.3390/cancers14010126

By:

Hill, Rebecca M.;
Plasschaert, Sabine L. A.;
Timmermann, Beate;
Dufour, Christelle;
Aquilina, Kristian;
Avula, Shivaram;
Donovan, Laura;
Lequin, Maarten;
Pietsch, Torsten;
Thomale, Ulrich;
Tippelt, Stephan;
Wesseling, Pieter;
Rutkowski, Stefan;
Clifford, Steven C.;
Pfister, Stefan M.;
Bailey, Simon;
Fleischhack, Gudrun

Publication type:

Article

Development of Randomized Trials in Adults with Medulloblastoma—The Example of EORTC 1634-BTG/NOA-23.

Published in:

Cancers, 2021, v. 13, n. 14, p. 3451, doi. 10.3390/cancers13143451

By:

Hau, Peter;
Frappaz, Didier;
Hovey, Elizabeth;
McCabe, Martin G.;
Pajtler, Kristian W.;
Wiestler, Benedikt;
Seidel, Clemens;
Combs, Stephanie E.;
Dirven, Linda;
Klein, Martin;
Anazodo, Antoinette;
Hattingen, Elke;
Hofer, Silvia;
Pfister, Stefan M.;
Zimmer, Claus;
Kortmann, Rolf-Dieter;
Sunyach, Marie-Pierre;
Tanguy, Ronan;
Effeney, Rachel;
von Deimling, Andreas

Publication type:

Article

High-Resolution Cartography of the Transcriptome and Methylome Landscapes of Diffuse Gliomas.

Published in:

Cancers, 2021, v. 13, n. 13, p. 3198, doi. 10.3390/cancers13133198

By:

Willscher, Edith;
Hopp, Lydia;
Kreuz, Markus;
Schmidt, Maria;
Hakobyan, Siras;
Arakelyan, Arsen;
Hentschel, Bettina;
Jones, David T. W.;
Pfister, Stefan M.;
Loeffler, Markus;
Loeffler-Wirth, Henry;
Binder, Hans

Publication type:

Article

From Sampling to Sequencing: A Liquid Biopsy Pre-Analytic Workflow to Maximize Multi-Layer Genomic Information from a Single Tube.

Published in:

Cancers, 2021, v. 13, n. 12, p. 3002, doi. 10.3390/cancers13123002

By:

Maass, Kendra K.;
Schad, Paulina S.;
Finster, Agnes M. E.;
Puranachot, Pitithat;
Rosing, Fabian;
Wedig, Tatjana;
Schwarz, Nathalie;
Stumpf, Natalie;
Pfister, Stefan M.;
Pajtler, Kristian W.

Publication type:

Article

Rapid and Sensitive Quantification of Osimertinib in Human Plasma Using a Fully Validated MALDI–IM–MS/MS Assay.

Published in:

Cancers, 2020, v. 12, n. 7, p. 1897, doi. 10.3390/cancers12071897

By:

Fresnais, Margaux;
Roth, André;
Foerster, Kathrin I.;
Jäger, Dirk;
Pfister, Stefan M.;
Haefeli, Walter E.;
Burhenne, Jürgen;
Longuespée, Rémi

Publication type:

Article

Machine learning workflows to estimate class probabilities for precision cancer diagnostics on DNA methylation microarray data.

Published in:

Nature Protocols, 2020, v. 15, n. 2, p. 479, doi. 10.1038/s41596-019-0251-6

By:

Maros, Máté E.;
Capper, David;
Jones, David T. W.;
Hovestadt, Volker;
von Deimling, Andreas;
Pfister, Stefan M.;
Benner, Axel;
Zucknick, Manuela;
Sill, Martin

Publication type:

Article

IDH mutation, glioma immunogenicity, and therapeutic challenge of primary mismatch repair deficient IDH‐mutant astrocytoma PMMRDIA: a systematic review.

Published in:

Molecular Oncology, 2024, v. 18, n. 12, p. 2822, doi. 10.1002/1878-0261.13598

By:

Ahmad, Olfat;
Ahmad, Tahani;
Pfister, Stefan M.

Publication type:

Article

Downregulation of miR‐326 and its host gene β‐arrestin1 induces pro‐survival activity of E2F1 and promotes medulloblastoma growth.

Published in:

Molecular Oncology, 2021, v. 15, n. 2, p. 523, doi. 10.1002/1878-0261.12800

By:

Miele, Evelina;
Po, Agnese;
Mastronuzzi, Angela;
Carai, Andrea;
Besharat, Zein Mersini;
Pediconi, Natalia;
Abballe, Luana;
Catanzaro, Giuseppina;
Sabato, Claudia;
De Smaele, Enrico;
Canettieri, Gianluca;
Di Marcotullio, Lucia;
Vacca, Alessandra;
Mai, Antonello;
Levrero, Massimo;
Pfister, Stefan M.;
Kool, Marcel;
Giangaspero, Felice;
Locatelli, Franco;
Ferretti, Elisabetta

Publication type:

Article

Diagnostics of pediatric supratentorial RELA ependymomas: integration of information from histopathology, genetics, DNA methylation and imaging.

Published in:

Brain Pathology, 2019, v. 29, n. 3, p. 325, doi. 10.1111/bpa.12664

By:

Pagès, Mélanie;
Pajtler, Kristian W.;
Puget, Stéphanie;
Castel, David;
Boddaert, Nathalie;
Tauziède‐Espariat, Arnault;
Picot, Stéphanie;
Debily, Marie‐Anne;
Kool, Marcel;
Capper, David;
Sainte‐Rose, Christian;
Chrétien, Fabrice;
Pfister, Stefan M.;
Pietsch, Torsten;
Grill, Jacques;
Varlet, Pascale;
Andreiuolo, Felipe

Publication type:

Article

Epithelioid glioblastomas stratify into established diagnostic subsets upon integrated molecular analysis.

Published in:

Brain Pathology, 2018, v. 28, n. 5, p. 656, doi. 10.1111/bpa.12566

By:

Korshunov, Andrey;
Chavez, Lukas;
Sharma, Tanvi;
Ryzhova, Marina;
Schrimpf, Daniel;
Stichel, Damian;
Capper, David;
Sturm, Dominik;
Kool, Marcel;
Habel, Antje;
Kleinschmidt‐DeMasters, Bette K.;
Rosenblum, Marc;
Absalyamova, Oksana;
Golanov, Andrey;
Lichter, Peter;
Pfister, Stefan M.;
Jones, David T.W.;
Perry, Arie;
von Deimling, Andreas

Publication type:

Article

cIMPACT-NOW (the consortium to inform molecular and practical approaches to CNS tumor taxonomy): a new initiative in advancing nervous system tumor classification.

Published in:

2017

By:

Louis, David N.;
Aldape, Ken;
Brat, Daniel J.;
Capper, David;
Ellison, David W.;
Hawkins, Cynthia;
Paulus, Werner;
Perry, Arie;
Reifenberger, Guido;
Figarella‐Branger, Dominique;
Wesseling, Pieter;
Batchelor, Tracy T.;
Gregory Cairncross, J.;
Pfister, Stefan M.;
Rutkowski, Stefan;
Weller, Michael;
Wick, Wolfgang;
von Deimling, Andreas

Publication type:

Other

Cribriform neuroepithelial tumor: molecular characterization of a SMARCB1-deficient non-rhabdoid tumor with favorable long-term outcome.

Published in:

Brain Pathology, 2017, v. 27, n. 4, p. 411, doi. 10.1111/bpa.12413

By:

Johann, Pascal D.;
Hovestadt, Volker;
Thomas, Christian;
Jeibmann, Astrid;
Heß, Katharina;
Bens, Susanne;
Oyen, Florian;
Hawkins, Cynthia;
Pierson, Christopher R.;
Aldape, Kenneth;
Kim, Sang‐Pyo;
Widing, Eva;
Sumerauer, David;
Hauser, Péter;
van Landeghem, Frank;
Ryzhova, Marina;
Korshunov, Andrey;
Capper, David;
Jones, David T.W.;
Pfister, Stefan M.

Publication type:

Article

Pediatric Targeted Therapy: Clinical Feasibility of Personalized Diagnostics in Children with Relapsed and Progressive Tumors.

Published in:

Brain Pathology, 2016, v. 26, n. 4, p. 506, doi. 10.1111/bpa.12326

By:

Selt, Florian;
Deiß, Alica;
Korshunov, Andrey;
Capper, David;
Witt, Hendrik;
van Tilburg, Cornelis M.;
Jones, David T. W.;
Witt, Ruth;
Sahm, Felix;
Reuss, David;
Kölsche, Christian;
Ecker, Jonas;
Oehme, Ina;
Hielscher, Thomas;
von Deimling, Andreas;
Kulozik, Andreas E.;
Pfister, Stefan M.;
Witt, Olaf;
Milde, Till

Publication type:

Article

The Role of Chromatin Remodeling in Medulloblastoma.

Published in:

Brain Pathology, 2013, v. 23, n. 2, p. 193, doi. 10.1111/bpa.12019

By:

Jones, David T. W.;
Northcott, Paul A.;
Kool, Marcel;
Pfister, Stefan M.

Publication type:

Article

Emerging Insights into the Ependymoma Epigenome.

Published in:

Brain Pathology, 2013, v. 23, n. 2, p. 206, doi. 10.1111/bpa.12020

By:

Mack, Stephen C.;
Witt, Hendrik;
Wang, Xin;
Milde, Till;
Yao, Yuan;
Bertrand, Kelsey C.;
Korshunov, Andrey;
Pfister, Stefan M.;
Taylor, Michael D.

Publication type:

Article

Nestin Expression Identifies Ependymoma Patients with Poor Outcome.

Published in:

Brain Pathology, 2012, v. 22, n. 6, p. 848, doi. 10.1111/j.1750-3639.2012.00600.x

By:

Milde, Till;
Hielscher, Thomas;
Witt, Hendrik;
Kool, Marcel;
Mack, Stephen C.;
Deubzer, Hedwig E.;
Oehme, Ina;
Lodrini, Marco;
Benner, Axel;
Taylor, Michael D.;
von Deimling, Andreas;
Kulozik, Andreas E.;
Pfister, Stefan M.;
Witt, Olaf;
Korshunov, Andrey

Publication type:

Article

Drivers underpinning the malignant transformation of giant cell tumour of bone.

Published in:

Journal of Pathology, 2020, v. 252, n. 4, p. 433, doi. 10.1002/path.5537

By:

Fittall, Matthew W;
Lyskjær, Iben;
Ellery, Peter;
Lombard, Patrick;
Ijaz, Jannat;
Strobl, Anna‐Christina;
Oukrif, Dahmane;
Tarabichi, Maxime;
Sill, Martin;
Koelsche, Christian;
Mechtersheimer, Gunhild;
Demeulemeester, Jonas;
Tirabosco, Roberto;
Amary, Fernanda;
Campbell, Peter J;
Pfister, Stefan M;
Jones, David TW;
Pillay, Nischalan;
Van Loo, Peter;
Behjati, Sam

Publication type:

Article

RF_Purify: a novel tool for comprehensive analysis of tumor-purity in methylation array data based on random forest regression.

Published in:

BMC Bioinformatics, 2019, v. 20, n. 1, p. N.PAG, doi. 10.1186/s12859-019-3014-z

By:

Johann, Pascal David;
Jäger, Natalie;
Pfister, Stefan M.;
Sill, Martin

Publication type:

Article

TelomereHunter – in silico estimation of telomere content and composition from cancer genomes.

Published in:

BMC Bioinformatics, 2019, v. 20, n. 1, p. 1, doi. 10.1186/s12859-019-2851-0

By:

Feuerbach, Lars;
Sieverling, Lina;
Deeg, Katharina I.;
Ginsbach, Philip;
Hutter, Barbara;
Buchhalter, Ivo;
Northcott, Paul A.;
Mughal, Sadaf S.;
Chudasama, Priya;
Glimm, Hanno;
Scholl, Claudia;
Lichter, Peter;
Fröhling, Stefan;
Pfister, Stefan M.;
Jones, David T. W.;
Rippe, Karsten;
Brors, Benedikt

Publication type:

Article

A cell-based model system links chromothripsis with hyperploidy.

Published in:

Molecular Systems Biology, 2015, v. 11, n. 9, p. n/a, doi. 10.15252/msb.20156505

By:

Mardin, Balca R;
Drainas, Alexandros P;
Waszak, Sebastian M;
Weischenfeldt, Joachim;
Isokane, Mayumi;
Stütz, Adrian M;
Raeder, Benjamin;
Efthymiopoulos, Theocharis;
Buccitelli, Christopher;
Segura-Wang, Maia;
Northcott, Paul;
Pfister, Stefan M;
Lichter, Peter;
Ellenberg, Jan;
Korbel, Jan O

Publication type:

Article

Important Requirements for the Selection of Internal Standards during the Development of Desorption/Ionization Assays for Drug Quantification in Biological Matrices—A Practical Example.

Published in:

Molecules, 2022, v. 27, n. 3, p. 690, doi. 10.3390/molecules27030690

By:

Fresnais, Margaux;
Karabulut, Seda;
Abou Zeed, Yasmin;
Ungermann, Johannes;
Benzel, Julia;
Pajtler, Kristian W.;
Pfister, Stefan M.;
Haefeli, Walter E.;
Burhenne, Jürgen;
Longuespée, Rémi

Publication type:

Article

Rapid MALDI-MS Assays for Drug Quantification in Biological Matrices: Lessons Learned, New Developments, and Future Perspectives.

Published in:

Molecules, 2021, v. 26, n. 5, p. 1281, doi. 10.3390/molecules26051281

By:

Fresnais, Margaux;
Yildirim, Esra;
Karabulut, Seda;
Jäger, Dirk;
Zörnig, Inka;
Benzel, Julia;
Pajtler, Kristian W.;
Pfister, Stefan M.;
Burhenne, Jürgen;
Haefeli, Walter E.;
Longuespée, Rémi;
Mandrioli, Roberto;
Mercolini, Laura;
Protti, Michele

Publication type:

Article

Clinically unfavorable transcriptome subtypes of non-WNT/non-SHH medulloblastomas are associated with a predominance in proliferating and progenitor-like cell subpopulations.

Published in:

Acta Neuropathologica, 2024, v. 147, n. 1, p. 1, doi. 10.1007/s00401-024-02746-6

By:

Okonechnikov, Konstantin;
Schrimpf, Daniel;
Koster, Jan;
Sievers, Philipp;
Milde, Till;
Sahm, Felix;
Jones, David T. W.;
von Deimling, Andreas;
Pfister, Stefan M.;
Kool, Marcel;
Korshunov, Andrey

Publication type:

Article

Transcriptome analysis stratifies second-generation non-WNT/non-SHH medulloblastoma subgroups into clinically tractable subtypes.

Published in:

Acta Neuropathologica, 2023, v. 145, n. 6, p. 829, doi. 10.1007/s00401-023-02575-z

By:

Korshunov, Andrey;
Okonechnikov, Konstantin;
Schrimpf, Daniel;
Tonn, Svenja;
Mynarek, Martin;
Koster, Jan;
Sievers, Philipp;
Milde, Till;
Sahm, Felix;
Jones, David T. W.;
von Deimling, Andreas;
Pfister, Stefan M.;
Kool, Marcel

Publication type:

Article

Molecular characterisation defines clinically-actionable heterogeneity within Group 4 medulloblastoma and improves disease risk-stratification.

Published in:

Acta Neuropathologica, 2023, v. 145, n. 5, p. 651, doi. 10.1007/s00401-023-02566-0

By:

Goddard, Jack;
Castle, Jemma;
Southworth, Emily;
Fletcher, Anya;
Crosier, Stephen;
Martin-Guerrero, Idoia;
García-Ariza, Miguel;
Navajas, Aurora;
Masliah-Planchon, Julien;
Bourdeaut, Franck;
Dufour, Christelle;
Ayrault, Olivier;
Goschzik, Tobias;
Pietsch, Torsten;
Sill, Martin;
Pfister, Stefan M.;
Rutkowski, Stefan;
Richardson, Stacey;
Hill, Rebecca M.;
Williamson, Daniel

Publication type:

Article

Epigenetic profiling reveals a subset of pediatric-type glioneuronal tumors characterized by oncogenic gene fusions involving several targetable kinases.

Published in:

Acta Neuropathologica, 2022, v. 144, n. 5, p. 1049, doi. 10.1007/s00401-022-02492-7

By:

Sievers, Philipp;
Sill, Martin;
Schrimpf, Daniel;
Friedel, Dennis;
Sturm, Dominik;
Gardberg, Maria;
Kurian, Kathreena M.;
Krskova, Lenka;
Vicha, Ales;
Schaller, Tina;
Hagel, Christian;
Abdullaev, Zied;
Aldape, Kenneth;
Jacques, Thomas S.;
Korshunov, Andrey;
Wick, Wolfgang;
Pfister, Stefan M.;
von Deimling, Andreas;
Jones, David T. W.;
Sahm, Felix

Publication type:

Article

Gene expression profiling of Group 3 medulloblastomas defines a clinically tractable stratification based on KIRREL2 expression.

Published in:

Acta Neuropathologica, 2022, v. 144, n. 2, p. 339, doi. 10.1007/s00401-022-02460-1

By:

Korshunov, Andrey;
Okonechnikov, Konstantin;
Stichel, Damian;
Schrimpf, Daniel;
Delaidelli, Alberto;
Tonn, Svenja;
Mynarek, Martin;
Sievers, Philipp;
Sahm, Felix;
Jones, David T. W.;
von Deimling, Andreas;
Pfister, Stefan M.;
Kool, Marcel

Publication type:

Article

Rapid-CNS<sup>2</sup>: rapid comprehensive adaptive nanopore-sequencing of CNS tumors, a proof-of-concept study.

Published in:

Acta Neuropathologica, 2022, v. 143, n. 5, p. 609, doi. 10.1007/s00401-022-02415-6

By:

Patel, Areeba;
Dogan, Helin;
Payne, Alexander;
Krause, Elena;
Sievers, Philipp;
Schoebe, Natalie;
Schrimpf, Daniel;
Blume, Christina;
Stichel, Damian;
Holmes, Nadine;
Euskirchen, Philipp;
Hench, Jürgen;
Frank, Stephan;
Rosenstiel-Goidts, Violaine;
Ratliff, Miriam;
Etminan, Nima;
Unterberg, Andreas;
Dieterich, Christoph;
Herold-Mende, Christel;
Pfister, Stefan M.

Publication type:

Article

EZHIP: a new piece of the puzzle towards understanding pediatric posterior fossa ependymoma.

Published in:

Acta Neuropathologica, 2022, v. 143, n. 1, p. 1, doi. 10.1007/s00401-021-02382-4

By:

Jenseit, Anne;
Camgöz, Aylin;
Pfister, Stefan M.;
Kool, Marcel

Publication type:

Article

CDKN2A/B homozygous deletion is associated with early recurrence in meningiomas.

Published in:

Acta Neuropathologica, 2020, v. 140, n. 3, p. 409, doi. 10.1007/s00401-020-02188-w

By:

Sievers, Philipp;
Hielscher, Thomas;
Schrimpf, Daniel;
Stichel, Damian;
Reuss, David E.;
Berghoff, Anna S.;
Neidert, Marian C.;
Wirsching, Hans-Georg;
Mawrin, Christian;
Ketter, Ralf;
Paulus, Werner;
Reifenberger, Guido;
Lamszus, Katrin;
Westphal, Manfred;
Etminan, Nima;
Ratliff, Miriam;
Herold-Mende, Christel;
Pfister, Stefan M.;
Jones, David T. W.;
Weller, Michael

Publication type:

Article

ETMR: a tumor entity in its infancy.

Published in:

Acta Neuropathologica, 2020, v. 140, n. 3, p. 249, doi. 10.1007/s00401-020-02182-2

By:

Lambo, Sander;
von Hoff, Katja;
Korshunov, Andrey;
Pfister, Stefan M.;
Kool, Marcel

Publication type:

Article

An optimized workflow to improve reliability of detection of KIAA1549:BRAF fusions from RNA sequencing data.

Published in:

Acta Neuropathologica, 2020, v. 140, n. 2, p. 237, doi. 10.1007/s00401-020-02167-1

By:

Sommerkamp, Alexander C.;
Uhrig, Sebastian;
Stichel, Damian;
St-Onge, Pascal;
Sun, Pengbo;
Jäger, Natalie;
von Deimling, Andreas;
Sahm, Felix;
Pfister, Stefan M.;
Korshunov, Andrey;
Sinnett, Daniel;
Jabado, Nada;
Wefers, Annika K.;
Jones, David T. W.

Publication type:

Article

Histone H3 wild-type DIPG/DMG overexpressing EZHIP extend the spectrum diffuse midline gliomas with PRC2 inhibition beyond H3-K27M mutation.

Published in:

Acta Neuropathologica, 2020, v. 139, n. 6, p. 1109, doi. 10.1007/s00401-020-02142-w

By:

Castel, David;
Kergrohen, Thomas;
Tauziède-Espariat, Arnault;
Mackay, Alan;
Ghermaoui, Samia;
Lechapt, Emmanuèle;
Pfister, Stefan M.;
Kramm, Christof M.;
Boddaert, Nathalie;
Blauwblomme, Thomas;
Puget, Stéphanie;
Beccaria, Kévin;
Jones, Chris;
Jones, David T. W.;
Varlet, Pascale;
Grill, Jacques;
Debily, Marie-Anne

Publication type:

Article

Posterior fossa pilocytic astrocytomas with oligodendroglial features show frequent FGFR1 activation via fusion or mutation.

Published in:

2020

By:

Sievers, Philipp;
Schrimpf, Daniel;
Stichel, Damian;
Reuss, David E.;
Hasselblatt, Martin;
Hagel, Christian;
Staszewski, Ori;
Hench, Jürgen;
Frank, Stephan;
Brandner, Sebastian;
Korshunov, Andrey;
Wick, Wolfgang;
Pfister, Stefan M.;
Reifenberger, Guido;
von Deimling, Andreas;
Sahm, Felix;
Jones, David T. W.

Publication type:

Letter

Routine RNA sequencing of formalin-fixed paraffin-embedded specimens in neuropathology diagnostics identifies diagnostically and therapeutically relevant gene fusions.

Published in:

Acta Neuropathologica, 2019, v. 138, n. 5, p. 827, doi. 10.1007/s00401-019-02039-3

By:

Stichel, Damian;
Schrimpf, Daniel;
Casalini, Belén;
Meyer, Jochen;
Wefers, Annika K.;
Sievers, Philipp;
Korshunov, Andrey;
Koelsche, Christian;
Reuss, David E.;
Reinhardt, Annekathrin;
Ebrahimi, Azadeh;
Fernández-Klett, Francisco;
Kessler, Tobias;
Sturm, Dominik;
Ecker, Jonas;
Milde, Till;
Herold-Mende, Christel;
Witt, Olaf;
Pfister, Stefan M.;
Wick, Wolfgang

Publication type:

Article

Molecular progression of SHH-activated medulloblastomas.

Published in:

2019

By:

Korshunov, Andrey;
Okonechnikov, Konstantin;
Sahm, Felix;
Ryzhova, Marina;
Stichel, Damian;
Sievers, Philipp;
Meyer, Jochen;
Schrimpf, Daniel;
Zheludkova, Olga;
Golanov, Andrey;
Lichter, Peter;
Jones, David T. W.;
Pfister, Stefan M.;
von Deimling, Andreas;
Kool, Marcel

Publication type:

Letter

cIMPACT-NOW update 4: diffuse gliomas characterized by MYB, MYBL1, or FGFR1 alterations or BRAF<sup>V600E</sup> mutation.

Published in:

Acta Neuropathologica, 2019, v. 137, n. 4, p. 683, doi. 10.1007/s00401-019-01987-0

By:

Ellison, David W.;
Hawkins, Cynthia;
Jones, David T. W.;
Pfister, Stefan M.;
Onar-Thomas, Arzu;
Reifenberger, Guido;
Louis, David N.

Publication type:

Article

Desmoplastic/nodular medulloblastomas (DNMB) and medulloblastomas with extensive nodularity (MBEN) disclose similar epigenetic signatures but different transcriptional profiles.

Published in:

Acta Neuropathologica, 2019, v. 137, n. 6, p. 1003, doi. 10.1007/s00401-019-01981-6

By:

Stichel, Damian;
Schrimpf, Daniel;
Casalini, Belen;
Sievers, Philipp;
Meyer, Jochen;
Sahm, Felix;
von Deimling, Andreas;
Korshunov, Andrey;
Jones, David T. W.;
Okonechnikov, Konstantin;
Kool, Marcel;
Pfister, Stefan M.;
Lichter, Peter;
Ryzhova, Marina;
Zheludkova, Olga;
Golanov, Andrey

Publication type:

Article

Two molecularly distinct atypical teratoid/rhabdoid tumors (or tumor components) occurring in an infant with rhabdoid tumor predisposition syndrome 1.

Published in:

2019

By:

Thomas, Christian;
Knerlich-Lukoschus, Friederike;
Reinhard, Harald;
Johann, Pascal D.;
Sturm, Dominik;
Sahm, Felix;
Bens, Susanne;
Vogt, Julia;
Nemes, Karolina;
Oyen, Florian;
Kordes, Uwe;
Siebert, Reiner;
Schneppenheim, Reinhard;
Messing-Jünger, Martina;
Pietsch, Torsten;
von Deimling, Andreas;
Paulus, Werner;
Pfister, Stefan M.;
Kool, Marcel;
Frühwald, Michael C.

Publication type:

Case Study