Works by Pfeffer, Lawrence

Results: 46

EIF5A2 controls ovarian tumor growth and metastasis by promoting epithelial to mesenchymal transition via the TGFβ pathway.

Published in:

Cell & Bioscience, 2021, v. 11, n. 1, p. 1, doi. 10.1186/s13578-021-00578-5

By:

Zhao, Guannan;
Zhang, Wenjing;
Dong, Peixin;
Watari, Hidemichi;
Guo, Yuqi;
Pfeffer, Lawrence M.;
Tigyi, Gabor;
Yue, Junming

Publication type:

Article

Knockout or inhibition of DHPS suppresses ovarian tumor growth and metastasis by attenuating the TGFβ pathway.

Published in:

Scientific Reports, 2025, v. 14, n. 1, p. 1, doi. 10.1038/s41598-025-85466-5

By:

Zhao, Guannan;
Zhao, Xinxin;
Liu, Ziping;
Wang, Baojin;
Dong, Peixin;
Watari, Hidemichi;
Pfeffer, Lawrence M.;
Tigyi, Gabor;
Zhang, Wenjing;
Yue, Junming

Publication type:

Article

The histone H3 lysine 56 acetylation pathway is regulated by target of rapamycin (TOR) signaling and functions directly in ribosomal RNA biogenesis.

Published in:

Nucleic Acids Research, 2012, v. 40, n. 14, p. 6534, doi. 10.1093/nar/gks345

By:

Chen, Hongfeng;
Fan, Meiyun;
Pfeffer, Lawrence M.;
Laribee, R. Nicholas

Publication type:

Article

MiR-675 Inhibits Primary Ovarian Tumor Growth and Metastasis by Suppressing EMT and TGFÎ² Signaling.

Published in:

Journal of Cancer, 2025, v. 16, n. 1, p. 55, doi. 10.7150/jca.102654

By:

Xinxin Zhao;
Ziping Liu;
Yongshuai Li;
Shiji Song;
Baojin Wang;
Pfeffer, Lawrence M.;
Wenjing Zhang;
Junming Yue

Publication type:

Article

Structural Activity Relationship Analysis of New Diphenyl PFI-3 Analogues Targeting for the Treatment of Glioblastoma.

Published in:

Pharmaceuticals (14248247), 2025, v. 18, n. 5, p. 608, doi. 10.3390/ph18050608

By:

Hwang, Dong-Jin;
Yang, Chuanhe;
Wang, Yinan;
Kelso, Hannah;
Pochampally, Satyanarayana;
Pfeffer, Lawrence M.;
Miller, Duane D.

Publication type:

Article

The STAT3-Regulated Autophagy Pathway in Glioblastoma.

Published in:

Pharmaceuticals (14248247), 2023, v. 16, n. 5, p. 671, doi. 10.3390/ph16050671

By:

Laribee, Ronald Nicholas;
Boucher, Andrew B.;
Madireddy, Saivikram;
Pfeffer, Lawrence M.

Publication type:

Article

Targeting the Bromodomain of BRG-1/BRM Subunit of the SWI/SNF Complex Increases the Anticancer Activity of Temozolomide in Glioblastoma.

Published in:

Pharmaceuticals (14248247), 2021, v. 14, n. 9, p. 904, doi. 10.3390/ph14090904

By:

Yang, Chuanhe;
Wang, Yinan;
Sims, Michelle M.;
He, Yali;
Miller, Duane D.;
Pfeffer, Lawrence M.

Publication type:

Article

Genetic and Epigenetic Alterations of CDH1 Regulatory Regions in Hereditary and Sporadic Gastric Cancer.

Published in:

Pharmaceuticals (14248247), 2021, v. 14, n. 5, p. 457, doi. 10.3390/ph14050457

By:

Tedaldi, Gianluca;
Molinari, Chiara;
São José, Celina;
Barbosa-Matos, Rita;
André, Ana;
Danesi, Rita;
Arcangeli, Valentina;
Ravegnani, Mila;
Saragoni, Luca;
Morgagni, Paolo;
Rebuzzi, Francesca;
Canale, Matteo;
Pignatta, Sara;
Ferracci, Elisa;
Martinelli, Giovanni;
Ranzani, Guglielmina Nadia;
Oliveira, Carla;
Calistri, Daniele;
Ulivi, Paola;
Pfeffer, Lawrence Marc

Publication type:

Article

APELA Expression in Glioma, and Its Association with Patient Survival and Tumor Grade.

Published in:

Pharmaceuticals (14248247), 2019, v. 12, n. 1, p. 45, doi. 10.3390/ph12010045

By:

Ganguly, Debolina;
Cai, Chun;
Sims, Michelle M.;
Yang, Chuan He;
Thomas, Matthew;
Cheng, Jinjun;
Saad, Ali G.;
Pfeffer, Lawrence M.

Publication type:

Article

The Type I IFN-Induced miRNA, miR-21.

Published in:

Pharmaceuticals (14248247), 2015, v. 8, n. 4, p. 836, doi. 10.3390/ph8040836

By:

Chuan He Yang;
Kui Li;
Pfeffer, Susan R.;
Pfeffer, Lawrence M.

Publication type:

Article

Brahma‐Related Gene‐1 (BRG1) promotes the malignant phenotype of glioblastoma cells.

Published in:

Journal of Cellular & Molecular Medicine, 2021, v. 25, n. 6, p. 2956, doi. 10.1111/jcmm.16330

By:

Wang, Yinan;
Yang, Chuan He;
Schultz, Andrew P.;
Sims, Michelle M.;
Miller, Duane D.;
Pfeffer, Lawrence M.

Publication type:

Article

Silencing the Double-Stranded RNA Binding Protein DGCR8 Inhibits Ovarian Cancer Cell Proliferation, Migration, and Invasion.

Published in:

Pharmaceutical Research, 2015, v. 32, n. 3, p. 769, doi. 10.1007/s11095-013-1219-9

By:

Guo, Yuqi;
Tian, Peng;
Yang, Chuanhe;
Liang, Zhibing;
Li, Min;
Sims, Michelle;
Lu, Lu;
Zhang, Zhan;
Li, Hongwei;
Pfeffer, Lawrence;
Yue, Junming

Publication type:

Article

Expression of the IFNα receptor in hairy cell leukaemia.

Published in:

British Journal of Haematology, 1992, v. 82, n. 3, p. 541, doi. 10.1111/j.1365-2141.1992.tb06464.x

By:

Platanias, Leonidas C.;
Pfeffer, Lawrence M.;
Barton, Kevin P.;
Vardiman, James W.;
Golomb, Harvey M.;
Colamonici, Oscar R.

Publication type:

Article

Systematic analysis of metastasis-associated genes identifies miR-17-5p as a metastatic suppressor of basal-like breast cancer.

Published in:

Breast Cancer Research & Treatment, 2014, v. 146, n. 3, p. 487, doi. 10.1007/s10549-014-3040-5

By:

Fan, Meiyun;
Sethuraman, Aarti;
Brown, Martin;
Sun, Wenlin;
Pfeffer, Lawrence

Publication type:

Article

Non-conventional signal transduction by type 1 interferons: The NF-κB pathway.

Published in:

Journal of Cellular Biochemistry, 2007, v. 102, n. 5, p. 1087, doi. 10.1002/jcb.21535

By:

Du, Ziyun;
Wei, Lai;
Murti, Aruna;
Pfeffer, Susan R.;
Fan, Meiyun;
Yang, Chuan He;
Pfeffer, Lawrence M.

Publication type:

Article

Renal cell carcinoma and interferon at the millennium.

Published in:

2001

By:

Pastore, Raymond D.;
Pfeffer, Lawrence M.;
Nanus, David M.;
Pastore, R D;
Pfeffer, L M;
Nanus, D M

Publication type:

journal article

Segregation of Histone Fractions from Purified Rat Pancreas Nuclei by Isoelectric Focusing.

Published in:

Proceedings of the Society for Experimental Biology & Medicine, 1976, v. 151, n. 2, p. 400, doi. 10.3181/00379727-151-39220

By:

Kopelovich, Levy;
Wolfe, Gloria;
Pfeffer, Lawrence

Publication type:

Article

ORIGINAL ARTICLE Corticotropin-Releasing Hormone Inhibits Nuclear Factor-κB Pathway in Human HaCaT Keratinocytes.

Published in:

Journal of Investigative Dermatology, 2003, v. 121, n. 6, p. 1496, doi. 10.1111/j.1523-1747.2003.12612.x

By:

Zbytek, Blazej;
Pfeffer, Lawrence M.;
Slominski, Andrzej T.

Publication type:

Article

FAK PROTAC Inhibits Ovarian Tumor Growth and Metastasis by Disrupting Kinase Dependent and Independent Pathways.

Published in:

Frontiers in Oncology, 2022, v. 12, p. 1, doi. 10.3389/fonc.2022.851065

By:

Huo, Xueyun;
Zhang, Wenjing;
Zhao, Guannan;
Chen, Zhenwen;
Dong, Peixin;
Watari, Hidemichi;
Narayanan, Ramesh;
Tillmanns, Todd D.;
Pfeffer, Lawrence M.;
Yue, Junming

Publication type:

Article

TSG-6 in conditioned media from adipose mesenchymal stem cells protects against visual deficits in mild traumatic brain injury model through neurovascular modulation.

Published in:

Stem Cell Research & Therapy, 2019, v. 10, n. 1, p. 1, doi. 10.1186/s13287-019-1436-1

By:

Jha, Kumar Abhiram;
Pentecost, Mickey;
Lenin, Raji;
Gentry, Jordy;
Klaic, Lada;
Del Mar, Nobel;
Reiner, Anton;
Yang, Chuan He;
Pfeffer, Lawrence M.;
Sohl, Nicolas;
Gangaraju, Rajashekhar

Publication type:

Article

Recombinant vesicular stomatitis virus vectors as oncolytic agents in the treatment of high-grade gliomas in an organotypic brain tissue slice-glioma coculture model.

Published in:

Journal of Neurosurgery, 2004, v. 100, n. 6, p. 1049, doi. 10.3171/jns.2004.100.6.1049

By:

Duntsch, Christopher D.;
Qihong Zhou;
Jayakar, Himangi R.;
Weimar, James D.;
Robertson, Jon H.;
Pfeffer, Lawrence M.;
Lie Wang;
Zixiu Xiang;
Whitt, Michael A.

Publication type:

Article

The Role of miR-21 in Cancer.

Published in:

Drug Development Research, 2015, v. 76, n. 6, p. 270, doi. 10.1002/ddr.21257

By:

Pfeffer, Susan R.;
Yang, Chuan He;
Pfeffer, Lawrence M.

Publication type:

Article

Lentiviral vector mediated-ASAP1 expression promotes epithelial to mesenchymal transition in ovarian cancer cells.

Published in:

Oncology Letters, 2018, v. 15, n. 4, p. 4432, doi. 10.3892/ol.2018.7834

By:

Zhang, Tao;
Zhao, Guannan;
Yang, Chuanhe;
Dong, Peixin;
Watari, Hidemichi;
Zeng, Lin;
Pfeffer, Lawrence M.;
Yue, Junming

Publication type:

Article

Design, Synthesis and Biological Evaluation of Novel 5H-Chromenopyridines as Potential Anti-Cancer Agents.

Published in:

Molecules, 2015, v. 20, n. 9, p. 17152, doi. 10.3390/molecules200917152

By:

Banerjee, Souvik;
Jin Wang;
Pfeffer, Susan;
Ma, Dejian;
Pfeffer, Lawrence M.;
Patil, Shivaputra A.;
Wei Li;
Miller, Duane D.

Publication type:

Article

reply: Kinase regulation in inflammatory response.

Published in:

Nature, 2000, v. 406, n. 6794, p. 368, doi. 10.1038/35019157

By:

Nidai Ozes, Osman;
Mayo, Lindsey D.;
Gustin, Jason A.;
Pfeffer, Susan R.;
Pfeffer, Lawrence M.;
Donner, David B.

Publication type:

Article

Kinase regulation in inflammatory response.

Published in:

Nature, 2000, v. 406, n. 6794, p. 367, doi. 10.1038/35019154

By:

Delhase, Mireille;
Nanxin Li;
Karin, Michael;
Ozes, Osman Nidai;
Mayo, Lindsey D.;
Gustin, Jason A.;
Pfeffer, Susan R.;
Pfeffer, Lawrence M.;
Donner, David B.

Publication type:

Article

Correction: Molecular Heterogeneity in a Patient-Derived Glioblastoma Xenoline Is Regulated by Different Cancer Stem Cell Populations.

Published in:

PLoS ONE, 2015, v. 10, n. 12, p. 1, doi. 10.1371/journal.pone.0145052

By:

Garner, Jo Meagan;
Ellison, David W.;
Finkelstein, David;
Ganguly, Debolina;
Du, Ziyun;
Sims, Michelle;
Yang, Chuan He;
Interiano, Rodrigo B.;
Davidoff, Andrew M.;
Pfeffer, Lawrence M.

Publication type:

Article

KLF4 Promotes Angiogenesis by Activating VEGF Signaling in Human Retinal Microvascular Endothelial Cells.

Published in:

PLoS ONE, 2015, v. 10, n. 6, p. 1, doi. 10.1371/journal.pone.0130341

By:

Wang, Yinan;
Yang, Chuanhe;
Gu, Qingqing;
Sims, Michelle;
Gu, Weiwang;
Pfeffer, Lawrence M.;
Yue, Junming

Publication type:

Article

Molecular Heterogeneity in a Patient-Derived Glioblastoma Xenoline Is Regulated by Different Cancer Stem Cell Populations.

Published in:

PLoS ONE, 2015, v. 10, n. 5, p. 1, doi. 10.1371/journal.pone.0125838

By:

Garner, Jo Meagan;
Ellison, David W.;
Finkelstein, David;
Ganguly, Debolina;
Du, Ziyun;
Sims, Michelle;
Yang, Chuan He;
Interiano, Rodrigo B.;
Davidoff, Andrew M.;
Pfeffer, Lawrence M.

Publication type:

Article

An Interferon Response Gene Signature Is Associated with the Therapeutic Response of Hepatitis C Patients.

Published in:

PLoS ONE, 2014, v. 9, n. 8, p. 1, doi. 10.1371/journal.pone.0104202

By:

Pfeffer, Lawrence M.;
Li, Kui;
Fleckenstein, Jaquelyn F.;
Marion, Tony N.;
Diament, Joel;
Yang, Chuan He;
Pfeffer, Susan R.;
Fan, Meiyun;
Handorf, Elizabeth;
Handorf, Charles R.

Publication type:

Article

The Curcumin Analog EF24 Targets NF-κB and miRNA-21, and Has Potent Anticancer Activity In Vitro and In Vivo.

Published in:

PLoS ONE, 2013, v. 8, n. 8, p. 1, doi. 10.1371/journal.pone.0071130

By:

Yang, Chuan He;
Yue, Junming;
Sims, Michelle;
Pfeffer, Lawrence M.

Publication type:

Article

Curcumin Potentiates Rhabdomyosarcoma Radiosensitivity by Suppressing NF-κB Activity.

Published in:

PLoS ONE, 2013, v. 8, n. 2, p. 1, doi. 10.1371/journal.pone.0051309

By:

Orr, W. Shannon;
Denbo, Jason W.;
Saab, Karim R.;
Ng, Catherine Y.;
Wu, Jianrong;
Li, Kui;
Garner, Jo Meagan;
Morton, Christopher L.;
Du, Ziyun;
Pfeffer, Lawrence M.;
Davidoff, Andrew M.

Publication type:

Article

20-Hydroxycholecalciferol, Product of Vitamin D3 Hydroxylation by P450scc, Decreases NF-κB Activity by Increasing IκBα Levels in Human Keratinocytes.

Published in:

PLoS ONE, 2009, v. 4, n. 6, p. 1, doi. 10.1371/journal.pone.0005988

By:

Janjetovic, Zorica;
Zmijewski, Michal A.;
Tuckey, Robert C.;
DeLeon, Damon A.;
Nguyen, Minh N.;
Pfeffer, Lawrence M.;
Slominski, Andrzej T.

Publication type:

Article

Growth characteristics of human skin fibroblasts in vitro: a simple experimental approach for the identification of hereditary adenomatosis of the colon and rectum.

Published in:

1979

By:

Kopelovich, Levy;
Pfeffer, Lawrence M.;
Bias, Nancy;
Kopelovich, L;
Pfeffer, L M;
Bias, N

Publication type:

journal article

Interferon inhibition of thymidine incorporation into DNA through effects on thymidine transport and uptake.

Published in:

Journal of Cellular Physiology, 1984, v. 121, n. 2, p. 431, doi. 10.1002/jcp.1041210223

By:

Pfeffer, Lawrence M.;
Tamm, Igor

Publication type:

Article

Growth abnormalities of cultured human skin fibroblasts derived from individuals with hereditary adenomatosis of the colon and rectum.

Published in:

Journal of Cellular Physiology, 1976, v. 89, n. 1, p. 29, doi. 10.1002/jcp.1040890104

By:

Pfeffer, Lawrence;
Lipkin, Martin;
Stutman, Osias;
Kopelovich, Levy

Publication type:

Article

Combining gene expression QTL mapping and phenotypic spectrum analysis to uncover gene regulatory relationships.

Published in:

Mammalian Genome, 2006, v. 17, n. 6, p. 575, doi. 10.1007/s00335-005-0172-2

By:

Lei Bao;
Lai Wei;
Peirce, Jeremy;
Homayouni, Ramin;
Hongqiang Li;
Mi Zhou;
Hao Chen;
Lu Lu;
Williams, Robert;
Pfeffer, Lawrence;
Goldowitz, Dan;
Yan Cui

Publication type:

Article

Lentiviral Vector Mediated Claudin1 Silencing Inhibits Epithelial to Mesenchymal Transition in Breast Cancer Cells.

Published in:

Viruses (1999-4915), 2015, v. 7, n. 6, p. 2965, doi. 10.3390/v7062755

By:

Xianqi Zhao;
Yanan Zou;
Qingqing Gu;
Guannan Zhao;
Gray, Horace;
Pfeffer, Lawrence M.;
Junming Yue

Publication type:

Article

miR-203 inhibits ovarian tumor metastasis by targeting BIRC5 and attenuating the TGFβ pathway.

Published in:

Journal of Experimental & Clinical Cancer Research (17569966), 2018, v. 37, n. 1, p. N.PAG, doi. 10.1186/s13046-018-0906-0

By:

Wang, Baojin;
Li, Xia;
Zhao, Guannan;
Yan, Huan;
Dong, Peixin;
Watari, Hidemichi;
Sims, Michelle;
Li, Wei;
Pfeffer, Lawrence M;
Guo, Yuqi;
Yue, Junming

Publication type:

Article

Androgen receptor agonists increase lean mass, improve cardiopulmonary functions and extend survival in preclinical models of Duchenne muscular dystrophy.

Published in:

Human Molecular Genetics, 2017, v. 26, n. 13, p. 2526, doi. 10.1093/hmg/ddx150

By:

Ponnusamy, Suriyan;
Sullivan, Ryan D.;
Dahui You;
Zafar, Nadeem;
Chuan He Yang;
Thiyagarajan, Thirumagal;
Johnson, Daniel L.;
Barrett, Maron L.;
Koehler, Nikki J.;
Star, Mayra;
Stephenson, Erin J.;
Bridges, Dave;
Cormier, Stephania A.;
Pfeffer, Lawrence M.;
Narayanan, Ramesh

Publication type:

Article

BHLHE40 confers a pro-survival and pro-metastatic phenotype to breast cancer cells by modulating HBEGF secretion.

Published in:

2018

By:

Sethuraman, Aarti;
Brown, Martin;
Krutilina, Raya;
Wu, Zhao-Hui;
Seagroves, Tiffany N.;
Pfeffer, Lawrence M.;
Fan, Meiyun

Publication type:

journal article

SMARCE1 regulates metastatic potential of breast cancer cells through the HIF1A/PTK2 pathway.

Published in:

2016

By:

Sethuraman, Aarti;
Brown, Martin;
Seagroves, Tiffany N.;
Zhao-Hui Wu;
Pfeffer, Lawrence M.;
Meiyun Fan;
Wu, Zhao-Hui;
Fan, Meiyun

Publication type:

journal article

Tyr1497 in the BRG1 Bromodomain of the SWI/SNF Complex is Critical for the Binding and Function of a Selective BRG1 Inhibitor.

Published in:

Journal of Cellular & Molecular Medicine, 2025, v. 29, n. 6, p. 1, doi. 10.1111/jcmm.70518

By:

Wang, Yinan;
Yang, Chuanhe;
Miranda‐Carboni, Gustavo A.;
Kelso, Hannah;
Seetharaman, Jayaraman;
Hwang, Dong‐Jin;
Miller, Duane D.;
Pfeffer, Lawrence M.

Publication type:

Article

Next‐generation bromodomain inhibitors of the SWI/SNF complex enhance DNA damage and cell death in glioblastoma.

Published in:

Journal of Cellular & Molecular Medicine, 2023, v. 27, n. 18, p. 2770, doi. 10.1111/jcmm.17907

By:

Yang, Chuanhe;
He, Yali;
Wang, Yinan;
McKinnon, Peter J.;
Shahani, Vijay;
Miller, Duane D.;
Pfeffer, Lawrence M.

Publication type:

Article

STAT3 regulates inflammatory cytokine production downstream of TNFR1 by inducing expression of TNFAIP3/A20.

Published in:

Journal of Cellular & Molecular Medicine, 2022, v. 26, n. 16, p. 4591, doi. 10.1111/jcmm.17489

By:

Antonia, Ricardo J.;
Karelehto, Eveliina;
Toriguchi, Kan;
Matli, Mary;
Warren, Robert S.;
Pfeffer, Lawrence M.;
Donner, David B.

Publication type:

Article

STAT3 suppresses the AMPKα/ULK1‐dependent induction of autophagy in glioblastoma cells.

Published in:

Journal of Cellular & Molecular Medicine, 2022, v. 26, n. 14, p. 3873, doi. 10.1111/jcmm.17421

By:

Bhattacharya, Sujoy;
Yin, Jinggang;
Yang, Chuanhe;
Wang, Yinan;
Sims, Michelle;
Pfeffer, Lawrence M.;
Chaum, Edward

Publication type:

Article