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Exploring Splicing Modulation as an Innovative Approach to Combat Pancreatic Cancer: SF3B1 Emerges as a Prognostic Indicator and Therapeutic Target.
- Published in:
- International Journal of Biological Sciences, 2024, v. 20, n. 9, p. 3173, doi. 10.7150/ijbs.92671
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- Publication type:
- Article
Newly synthesized acridone derivatives targeting lung cancer: A toxicity and xenograft model study.
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- Drug Development Research, 2024, v. 85, n. 4, p. 1, doi. 10.1002/ddr.22212
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- Publication type:
- Article
Exploring Splicing Modulation as an Innovative Approach to Combat Pancreatic Cancer: SF3B1 Emerges as a Prognostic Indicator and Therapeutic Target.
- Published in:
- International Journal of Biological Sciences, 2024, v. 20, n. 8, p. 3173, doi. 10.7150/ijbs.92671
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- Publication type:
- Article
Exploring the role of oxidative stress and the effect of N‐acetylcysteine in thiopurine‐induced liver injury in inflammatory bowel disease: A randomized crossover pilot study.
- Published in:
- Basic & Clinical Pharmacology & Toxicology, 2024, v. 134, n. 4, p. 507, doi. 10.1111/bcpt.13978
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- Publication type:
- Article
G-Protein Signaling Modulator 2 as a Potential Biomarker in Colorectal Cancer: Integrative Analysis Using Genetic Profiling and Pan-Cancer Studies.
- Published in:
- Genes, 2024, v. 15, n. 4, p. 474, doi. 10.3390/genes15040474
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- Publication type:
- Article
Targeting miRNA and using miRNA as potential therapeutic options to bypass resistance in pancreatic ductal adenocarcinoma.
- Published in:
- Cancer & Metastasis Reviews, 2023, v. 42, n. 3, p. 725, doi. 10.1007/s10555-023-10127-w
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- Publication type:
- Article
The Prognostic Value of ASPHD1 and ZBTB12 in Colorectal Cancer: A Machine Learning-Based Integrated Bioinformatics Approach.
- Published in:
- Cancers, 2023, v. 15, n. 17, p. 4300, doi. 10.3390/cancers15174300
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- Publication type:
- Article
Target Therapy in Malignant Pleural Mesothelioma: Hope or Mirage?
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- International Journal of Molecular Sciences, 2023, v. 24, n. 11, p. 9165, doi. 10.3390/ijms24119165
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- Publication type:
- Article
Metabolic Effects of New Glucose Transporter (GLUT-1) and Lactate Dehydrogenase-A (LDH-A) Inhibitors against Chemoresistant Malignant Mesothelioma.
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- International Journal of Molecular Sciences, 2023, v. 24, n. 9, p. 7771, doi. 10.3390/ijms24097771
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- Publication type:
- Article
A New Oxadiazole-Based Topsentin Derivative Modulates Cyclin-Dependent Kinase 1 Expression and Exerts Cytotoxic Effects on Pancreatic Cancer Cells.
- Published in:
- Molecules, 2022, v. 27, n. 1, p. 19, doi. 10.3390/molecules27010019
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- Publication type:
- Article
Carboplatin Dosing in Children Using Estimated Glomerular Filtration Rate: Equation Matters.
- Published in:
- Cancers, 2021, v. 13, n. 23, p. 5963, doi. 10.3390/cancers13235963
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- Publication type:
- Article
A bug in the resistance to EGFR inhibitors: is there a role for Mycoplasma and cytidine deaminase in reducing the activity of osimertinib in lung cancer patients?
- Published in:
- 2021
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- Publication type:
- Letter
Cyclin Dependent Kinase-1 (CDK-1) Inhibition as a Novel Therapeutic Strategy against Pancreatic Ductal Adenocarcinoma (PDAC).
- Published in:
- Cancers, 2021, v. 13, n. 17, p. 4389, doi. 10.3390/cancers13174389
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- Publication type:
- Article
High Temperature Drives Topoisomerase Mediated Chromosomal Break Repair Pathway Choice.
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- Cancers, 2021, v. 13, n. 10, p. 2315, doi. 10.3390/cancers13102315
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- Publication type:
- Article
An Evaluation of the Diagnostic Accuracy of a Panel of Variants in DPYD and a Single Variant in ENOSF1 for Predicting Common Capecitabine Related Toxicities.
- Published in:
- Cancers, 2021, v. 13, n. 7, p. 1497, doi. 10.3390/cancers13071497
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- Publication type:
- Article
<sup>11</sup>C-sorafenib and <sup>15</sup>O-H<sub>2</sub>O PET for early evaluation of sorafenib therapy.
- Published in:
- Journal of Nuclear Medicine, 2020, v. 61, n. 12, p. 1, doi. 10.2967/jnumed.120.251611
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- Publication type:
- Article
"Open Sesame?": Biomarker Status of the Human Equilibrative Nucleoside Transporter-1 and Molecular Mechanisms Influencing its Expression and Activity in the Uptake and Cytotoxicity of Gemcitabine in Pancreatic Cancer.
- Published in:
- Cancers, 2020, v. 12, n. 11, p. 3206, doi. 10.3390/cancers12113206
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- Publication type:
- Article
Epithelial Transfer of the Tyrosine Kinase Inhibitors Erlotinib, Gefitinib, Afatinib, Crizotinib, Sorafenib, Sunitinib, and Dasatinib: Implications for Clinical Resistance.
- Published in:
- Cancers, 2020, v. 12, n. 11, p. 3322, doi. 10.3390/cancers12113322
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- Publication type:
- Article
Crizotinib sensitizes the erlotinib resistant HCC827GR5 cell line by influencing lysosomal function.
- Published in:
- Journal of Cellular Physiology, 2020, v. 235, n. 11, p. 8085, doi. 10.1002/jcp.29463
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- Publication type:
- Article
<sup>11</sup>C-sorafenib and <sup>15</sup>O-H<sub>2</sub>O PET for early evaluation of sorafenib therapy.
- Published in:
- Journal of Nuclear Medicine, 2020, v. 61, n. 11, p. 1, doi. 10.2967/jnumed.120.251611
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- Publication type:
- Article
Comment on: Targeting the HGF/c-MET pathway in advanced pancreatic cancer: a key element of treatment that limits primary tumour growth and eliminates metastasis.
- Published in:
- 2020
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- Publication type:
- letter
Pancreatic cancer resistance conferred by stellate cells: looking for new preclinical models.
- Published in:
- 2020
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- Publication type:
- Letter
NUC-1031 in biliary tract cancer: from bench to bedside and back?
- Published in:
- 2020
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- Publication type:
- editorial
RX-3117 (Fluorocyclopentenyl-Cytosine)-Mediated Down-Regulation of DNA Methyltransferase 1 Leads to Protein Expression of Tumor-Suppressor Genes and Increased Functionality of the Proton-Coupled Folate Carrier.
- Published in:
- International Journal of Molecular Sciences, 2020, v. 21, n. 8, p. 2717, doi. 10.3390/ijms21082717
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- Publication type:
- Article
Kinase Inhibitor Treatment of Patients with Advanced Cancer Results in High Tumor Drug Concentrations and in Specific Alterations of the Tumor Phosphoproteome.
- Published in:
- Cancers, 2020, v. 12, n. 2, p. 330, doi. 10.3390/cancers12020330
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- Publication type:
- Article
3-(6-Phenylimidazo [2,1-b][1,3,4]thiadiazol-2-yl)-1H-Indole Derivatives as New Anticancer Agents in the Treatment of Pancreatic Ductal Adenocarcinoma.
- Published in:
- Molecules, 2020, v. 25, n. 2, p. 329, doi. 10.3390/molecules25020329
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- Publication type:
- Article
The Role of c-Met as a Biomarker and Player in Innate and Acquired Resistance in Non-Small-Cell Lung Cancer: Two New Mutations Warrant Further Studies.
- Published in:
- Molecules, 2019, v. 24, n. 24, p. 4443, doi. 10.3390/molecules24244443
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- Publication type:
- Article
CX-5461 Inhibits Pancreatic Ductal Adenocarcinoma Cell Growth, Migration and Induces DNA Damage.
- Published in:
- Molecules, 2019, v. 24, n. 24, p. 4445, doi. 10.3390/molecules24244445
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- Publication type:
- Article
Thiopurines with low-dose allopurinol (ThiLDA)—a prospective clinical one-way crossover trial.
- Published in:
- European Journal of Clinical Pharmacology, 2019, v. 75, n. 12, p. 1669, doi. 10.1007/s00228-019-02760-8
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- Publication type:
- Article
Coexisting Molecular Determinants of Acquired Oxaliplatin Resistance in Human Colorectal and Ovarian Cancer Cell Lines.
- Published in:
- International Journal of Molecular Sciences, 2019, v. 20, n. 15, p. 3619, doi. 10.3390/ijms20153619
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- Publication type:
- Article
Can cytidine deaminase be used as predictive biomarker for gemcitabine toxicity and response?
- Published in:
- British Journal of Clinical Pharmacology, 2019, v. 85, n. 6, p. 1213, doi. 10.1111/bcp.13921
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- Publication type:
- Article
Role of c-MET Inhibitors in Overcoming Drug Resistance in Spheroid Models of Primary Human Pancreatic Cancer and Stellate Cells.
- Published in:
- Cancers, 2019, v. 11, n. 5, p. 638, doi. 10.3390/cancers11050638
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- Publication type:
- Article
Folate receptors and transporters: biological role and diagnostic/therapeutic targets in cancer and other diseases.
- Published in:
- Journal of Experimental & Clinical Cancer Research (17569966), 2019, v. 38, n. 1, p. N.PAG, doi. 10.1186/s13046-019-1123-1
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- Publication type:
- Article
Transporter and Lysosomal Mediated (Multi)drug Resistance to Tyrosine Kinase Inhibitors and Potential Strategies to Overcome Resistance.
- Published in:
- Cancers, 2018, v. 10, n. 12, p. 503, doi. 10.3390/cancers10120503
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- Publication type:
- Article
Cytidine deaminase enzymatic activity is a prognostic biomarker in gemcitabine/platinum-treated advanced non-small-cell lung cancer: a prospective validation study.
- Published in:
- 2018
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- Publication type:
- journal article
Proteasome inhibition and mechanism of resistance to a synthetic, library-based hexapeptide.
- Published in:
- Investigational New Drugs, 2018, v. 36, n. 5, p. 797, doi. 10.1007/s10637-018-0569-x
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- Publication type:
- Article
Cellular pharmacology studies of anticancer agents: recommendations from the EORTC-PAMM group.
- Published in:
- 2018
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- Publication type:
- journal article
Double Trouble: A Case Series on Concomitant Genetic Aberrations in NSCLC.
- Published in:
- 2018
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- Publication type:
- journal article
The potential of multi-compound nanoparticles to bypass drug resistance in cancer.
- Published in:
- 2017
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- Publication type:
- journal article
Pharmacologically directed strategies in academic anticancer drug discovery based on the European NCI compounds initiative.
- Published in:
- 2017
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- Publication type:
- journal article
The allosteric AKT inhibitor MK2206 shows a synergistic interaction with chemotherapy and radiotherapy in glioblastoma spheroid cultures.
- Published in:
- 2017
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- Publication type:
- journal article
Phospho-Akt overexpression is prognostic and can be used to tailor the synergistic interaction of Akt inhibitors with gemcitabine in pancreatic cancer.
- Published in:
- Journal of Hematology & Oncology, 2017, v. 10, p. 1, doi. 10.1186/s13045-016-0371-1
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- Publication type:
- Article
hENT-1 Expression and Localization Predict Outcome After Adjuvant Gemcitabine in Resected Cholangiocarcinoma Patients.
- Published in:
- 2016
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- Publication type:
- Letter to the Editor
New developments in the management of nonsmall-cell lung cancer, focus on rociletinib: what went wrong?
- Published in:
- OncoTargets & Therapy, 2016, v. 9, p. 6065, doi. 10.2147/OTT.S97644
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- Publication type:
- Article
Adherence and Patients' Experiences with the Use of Capecitabine in Daily Practice.
- Published in:
- Frontiers in Pharmacology, 2016, p. 1, doi. 10.3389/fphar.2016.00310
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- Publication type:
- Article
The Cytidine Analog Fluorocyclopentenylcytosine (RX-3117) Is Activated by Uridine-Cytidine Kinase 2.
- Published in:
- PLoS ONE, 2016, v. 11, n. 9, p. 1, doi. 10.1371/journal.pone.0162901
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- Publication type:
- Article
Alternative scheduling of pulsatile, high dose sunitinib efficiently suppresses tumor growth.
- Published in:
- Journal of Experimental & Clinical Cancer Research (17569966), 2016, v. 35, p. 1, doi. 10.1186/s13046-016-0411-2
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- Publication type:
- Article
Pharmacokinetics and pharmacogenetics of Gemcitabine as a mainstay in adult and pediatric oncology: an EORTC-PAMM perspective.
- Published in:
- 2016
- By:
- Publication type:
- journal article
Folylpolyglutamate synthetase splicing alterations in acute lymphoblastic leukemia are provoked by methotrexate and other chemotherapeutics and mediate chemoresistance.
- Published in:
- International Journal of Cancer, 2016, v. 138, n. 7, p. 1645, doi. 10.1002/ijc.29919
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- Publication type:
- Article
Contemporary reviews on cancer treatment.
- Published in:
- 2016
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- Publication type:
- journal article