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Comparison of the urinary glucose excretion contributions of SGLT2 and SGLT1: A quantitative systems pharmacology analysis in healthy individuals and patients with type 2 diabetes treated with SGLT2 inhibitors.
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- Diabetes, Obesity & Metabolism, 2019, v. 21, n. 12, p. 2684, doi. 10.1111/dom.13858
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- Article
Comparison of the urinary glucose excretion contributions of SGLT2 and SGLT1: A quantitative systems pharmacology analysis in healthy individuals and patients with type 2 diabetes treated with SGLT2 inhibitors.
- Published in:
- Diabetes, Obesity & Metabolism, 2019, v. 21, n. 12, p. 2684, doi. 10.1111/dom.13858
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- Publication type:
- Article
Exenatide effects on gastric emptying rate and the glucose rate of appearance in plasma: A quantitative assessment using an integrative systems pharmacology model.
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- Diabetes, Obesity & Metabolism, 2018, v. 20, n. 8, p. 2034, doi. 10.1111/dom.13326
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- Article
DBSolve Optimum: a software package for kinetic modeling which allows dynamic visualization of simulation results.
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- BMC Systems Biology, 2010, v. 4, p. 109, doi. 10.1186/1752-0509-4-109
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- Article
Optimization of the MACE endpoint composition to increase power in studies of lipid-lowering therapies--a model-based meta-analysis.
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- Frontiers in Cardiovascular Medicine, 2024, p. 1, doi. 10.3389/fcvm.2023.1242845
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- Article
Quantification of Scheduling Impact on Safety and Efficacy Outcomes of Brain Metastasis Radio- and Immuno-Therapies: A Systematic Review and Meta-Analysis.
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- Frontiers in Oncology, 2020, v. 10, p. N.PAG, doi. 10.3389/fonc.2020.01609
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- Article
Mathematical modeling of endogenous and exogenously administered T cell recirculation in mouse and its application to pharmacokinetic studies of cell therapies.
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- Frontiers in Immunology, 2024, p. 1, doi. 10.3389/fimmu.2024.1357706
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- Article
Longitudinal FEV<sub>1</sub> and Exacerbation Risk in COPD: Quantifying the Association Using Joint Modelling.
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- International Journal of COPD, 2021, v. 16, p. 101, doi. 10.2147/COPD.S284720
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- Article
Evaluation of therapeutic strategies targeting BCAA catabolism using a systems pharmacology model.
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- Frontiers in Pharmacology, 2022, v. 13, p. 1, doi. 10.3389/fphar.2022.993422
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- Article
Role of T Cell-To-Dendritic Cell Chemoattraction in T Cell Priming Initiation in the Lymph Node: An Agent-Based Modeling Study.
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- Frontiers in Immunology, 2019, p. N.PAG, doi. 10.3389/fimmu.2019.01289
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- Article
Quantitative Mechanistic Modeling in Support of Pharmacological Therapeutics Development in Immuno-Oncology.
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- Frontiers in Immunology, 2019, p. N.PAG, doi. 10.3389/fimmu.2019.00924
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- Article
Applications of Model-Based Meta-Analysis in Drug Development.
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- Pharmaceutical Research, 2022, v. 39, n. 8, p. 1761, doi. 10.1007/s11095-022-03201-5
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- Article
KINETIC MODELING OF ACE OPERON GENETIC REGULATION IN ESCHERICHIA COLI.
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- Journal of Bioinformatics & Computational Biology, 2008, v. 6, n. 5, p. 933, doi. 10.1142/S0219720008003771
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- Article
KINETIC MODEL OF PHOSPHOFRUCTOKINASE-1 FROM ESCHERICHIA COLI.
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- Journal of Bioinformatics & Computational Biology, 2008, v. 6, n. 4, p. 843, doi. 10.1142/S0219720008003643
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- Article
Population Pharmacokinetic and Pharmacodynamic Modeling of Romiplostim Biosimilar GP40141 and Reference Product in Healthy Volunteers to Evaluate Biosimilarity.
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- Clinical Pharmacology in Drug Development, 2024, v. 13, n. 4, p. 419, doi. 10.1002/cpdd.1367
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- Article
Interpretation of metabolic memory phenomenon using a physiological systems model: What drives oxidative stress following glucose normalization?
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- PLoS ONE, 2017, v. 12, n. 2, p. 1, doi. 10.1371/journal.pone.0171781
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- Article
Mathematical modeling of endogenous and exogenously administered T cell recirculation in mouse and its application to pharmacokinetic studies of cell therapies.
- Published in:
- Frontiers in Immunology, 2024, p. 1, doi. 10.3389/fimmu.2024.1357706
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- Publication type:
- Article
Mathematical modeling in autoimmune diseases: from theory to clinical application.
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- Frontiers in Immunology, 2024, p. 1, doi. 10.3389/fimmu.2024.1371620
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- Article
An integrative mechanistic model of thymocyte dynamics.
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- Frontiers in Immunology, 2024, p. 1, doi. 10.3389/fimmu.2024.1321309
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- Article
Model-Based Assessment of the Reference Values of CAVI in Healthy Russian Population and Benchmarking With CAVI0.
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- American Journal of Hypertension, 2024, v. 37, n. 1, p. 77, doi. 10.1093/ajh/hpad082
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A tutorial for model‐based evaluation and translation of cardiovascular safety in preclinical trials.
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- CPT: Pharmacometrics & Systems Pharmacology, 2024, v. 13, n. 1, p. 5, doi. 10.1002/psp4.13082
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- Article
A workflow for the joint modeling of longitudinal and event data in the development of therapeutics: Tools, statistical methods, and diagnostics.
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- CPT: Pharmacometrics & Systems Pharmacology, 2022, v. 11, n. 4, p. 425, doi. 10.1002/psp4.12763
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- Article
Longitudinal Tumor Size and Neutrophil‐to‐Lymphocyte Ratio Are Prognostic Biomarkers for Overall Survival in Patients With Advanced Non‐Small Cell Lung Cancer Treated With Durvalumab.
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- CPT: Pharmacometrics & Systems Pharmacology, 2021, v. 10, n. 1, p. 67, doi. 10.1002/psp4.12578
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- Article
Differentiating the Sodium‐Glucose Cotransporter 1 Inhibition Capacity of Canagliflozin vs. Dapagliflozin and Empagliflozin Using Quantitative Systems Pharmacology Modeling.
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- CPT: Pharmacometrics & Systems Pharmacology, 2020, v. 9, n. 4, p. 222, doi. 10.1002/psp4.12498
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- Article
Quantitative Systems Pharmacology: An Exemplar Model-Building Workflow With Applications in Cardiovascular, Metabolic, and Oncology Drug Development.
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- CPT: Pharmacometrics & Systems Pharmacology, 2019, v. 8, n. 6, p. 380, doi. 10.1002/psp4.12426
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Evaluation of Combination Strategies for the A<sub>2A</sub>R Inhibitor AZD4635 Across Tumor Microenvironment Conditions via a Systems Pharmacology Model.
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- Frontiers in Immunology, 2021, p. N.PAG, doi. 10.3389/fimmu.2021.617316
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- Article
Cycle Network Model of Prostaglandin H Synthase-1.
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- Pharmaceuticals (14248247), 2020, v. 13, n. 10, p. 265, doi. 10.3390/ph13100265
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- Article
Agent Based Modeling of Human Gut Microbiome Interactions and Perturbations.
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- PLoS ONE, 2016, v. 11, n. 2, p. 1, doi. 10.1371/journal.pone.0148386
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Kinetic modelling of central carbon metabolism in Escherichia coli.
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- FEBS Journal, 2012, v. 279, n. 18, p. 3374, doi. 10.1111/j.1742-4658.2012.08719.x
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- Article