Works matching AU Perrin, J.


Results: 294
    1

    Relationships of PGRN with sTREM2 in AD continuum and non-AD pathophysiology and their reciprocal roles in modulating amyloid pathology: two population-based study.

    Published in:
    Translational Psychiatry, 2025, v. 15, n. 1, p. 1, doi. 10.1038/s41398-025-03457-6
    By:
    • Huang, Liang-Yu;
    • Tan, Chen-Chen;
    • Xu, Wei;
    • Tan, Lan;
    • Weiner, Michael W.;
    • Aisen, Paul;
    • Petersen, Ronald;
    • Jack Jr, Clifford R.;
    • Jagust, William;
    • Trojanowki, John Q.;
    • Toga, Arthur W.;
    • Beckett, Laurel;
    • Green, Robert C.;
    • Saykin, Andrew J.;
    • Morris, John C.;
    • Perrin, Richard J.;
    • Shaw, Leslie M.;
    • Carrillo, Maria;
    • Potter, William;
    • Barnes, Lisa
    Publication type:
    Article
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    Comparative neurofilament light chain trajectories in CSF and plasma in autosomal dominant Alzheimer's disease.

    Published in:
    Nature Communications, 2024, v. 15, n. 1, p. 1, doi. 10.1038/s41467-024-52937-8
    By:
    • Hofmann, Anna;
    • Häsler, Lisa M.;
    • Lambert, Marius;
    • Kaeser, Stephan A.;
    • Gräber-Sultan, Susanne;
    • Obermüller, Ulrike;
    • Kuder-Buletta, Elke;
    • la Fougere, Christian;
    • Laske, Christoph;
    • Vöglein, Jonathan;
    • Levin, Johannes;
    • Fox, Nick C.;
    • Ryan, Natalie S.;
    • Zetterberg, Henrik;
    • Llibre-Guerra, Jorge J.;
    • Perrin, Richard J.;
    • Ibanez, Laura;
    • Schofield, Peter R.;
    • Brooks, William S.;
    • Day, Gregory S.
    Publication type:
    Article
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    Book Reviews.

    Published in:
    2002
    By:
    • Williams, James L.;
    • Sandhu, Amandeep;
    • Spraggins, Johnnie D.;
    • Ellison, Nicole;
    • Jacobson, Beth Pamela;
    • Nayar, Pramod K.;
    • Rooney, Bobbie J.;
    • Nesbary, Dale K.;
    • Perrin, Andrew J.
    Publication type:
    Book Review
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    Ubiquitin–proteasome system in the different stages of dominantly inherited Alzheimer's disease.

    Published in:
    Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2025, v. 21, n. 5, p. 1, doi. 10.1002/alz.70243
    By:
    • Liu, Haiyan;
    • Bui, Quoc;
    • Hassenstab, Jason;
    • Gordon, Brian A.;
    • Benzinger, Tammie L. S.;
    • Timsina, Jigyasha;
    • Sung, Yun Ju;
    • Karch, Celeste;
    • Renton, Alan E.;
    • Daniels, Alisha;
    • Morris, John C.;
    • Xiong, Chengjie;
    • Ibanez, Laura;
    • Perrin, Richard J.;
    • Llibre‐Guerra, Jorge J.;
    • Day, Gregory S.;
    • Supnet‐Bell, Charlene;
    • Xu, Xiong;
    • Berman, Sarah B.;
    • Chhatwal, Jasmeer P.
    Publication type:
    Article
    23

    Overview of Alzheimer's Disease Neuroimaging Initiative and future clinical trials.

    Published in:
    Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2025, v. 21, n. 1, p. 1, doi. 10.1002/alz.14321
    By:
    • Weiner, Michael W.;
    • Kanoria, Shaveta;
    • Miller, Melanie J.;
    • Aisen, Paul S.;
    • Beckett, Laurel A.;
    • Conti, Catherine;
    • Diaz, Adam;
    • Flenniken, Derek;
    • Green, Robert C.;
    • Harvey, Danielle J.;
    • Jack, Clifford R.;
    • Jagust, William;
    • Lee, Edward B.;
    • Morris, John C.;
    • Nho, Kwangsik;
    • Nosheny, Rachel;
    • Okonkwo, Ozioma C.;
    • Perrin, Richard J.;
    • Petersen, Ronald C.;
    • Rivera‐Mindt, Monica
    Publication type:
    Article
    24

    CSF proteomics related to the neurovascular unit are associated with white matter hyperintensity volumes and cerebral microhemorrhages in autosomal dominant Alzheimer disease.

    Published in:
    Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2024, v. 20, n. S9, p. 1, doi. 10.1002/alz.093619
    By:
    • Joseph‐Mathurin, Nelly;
    • Shen, Yuanyuan;
    • Friedrichsen, Karl A.;
    • Chen, Charles D.;
    • McCullough, Austin A.;
    • Strain, Jeremy F.;
    • Shirzadi, Zahra;
    • Chen, Gengsheng;
    • Massoumzadeh, Parinaz;
    • Gordon, Brian A.;
    • Llibre‐Guerra, Jorge J.;
    • Hassenstab, Jason J.;
    • Ibanez, Laura;
    • Lu, Ruijin;
    • Schultz, Stephanie A.;
    • Chhatwal, Jasmeer P.;
    • Morris, John C.;
    • Perrin, Richard J.;
    • An, Hongyu;
    • Xiong, Chengjie
    Publication type:
    Article
    25

    Evaluating brain age using functional connectivity in autosomal dominant Alzheimer disease.

    Published in:
    Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2024, v. 20, n. S9, p. 1, doi. 10.1002/alz.093634
    By:
    • Macharia, Kiana Angela;
    • Gordon, Brian A.;
    • Wisch, Julie K.;
    • Metcalf, Nicholas V;
    • Roman, June;
    • Benzinger, Tammie L.S.;
    • Cruchaga, Carlos;
    • Goate, Alison M.;
    • Hassenstab, Jason J.;
    • Ibanez, Laura;
    • Karch, Celeste M.;
    • Llibre‐Guerra, Jorge J.;
    • Morris, John C.;
    • Perrin, Richard J.;
    • Renton, Alan E.;
    • Supnet, Charlene B;
    • Xiong, Chengjie;
    • Bateman, Randall J.;
    • McDade, Eric;
    • Ances, Beau
    Publication type:
    Article
    26

    Modeling the influence of presenilin‐1 mutation position on primary outcomes of a gantenerumab trial: findings from the DIAN‐TU‐001 study.

    Published in:
    Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2024, v. 20, n. S8, p. 1, doi. 10.1002/alz.095570
    By:
    • McCullough, Austin A.;
    • Cao, Yuchen;
    • Chen, Charles D.;
    • Gordon, Brian A.;
    • Cruchaga, Carlos;
    • Goate, Alison M.;
    • Hassenstab, Jason J.;
    • Ibanez, Laura;
    • Li, Yan;
    • Perrin, Richard J.;
    • Renton, Alan E.;
    • Xiong, Chengjie;
    • Salloway, Stephen;
    • Llibre‐Guerra, Jorge J.;
    • Clifford, David B.;
    • McDade, Eric;
    • Bateman, Randall J.;
    • Benzinger, Tammie L.S.;
    • Wang, Guoqiao;
    • Joseph‐Mathurin, Nelly
    Publication type:
    Article
    27

    Anti‐amyloid‐β treatment effects on dominantly inherited Alzheimer disease neuropathology: comparing autopsy findings with biomarker outcomes from the DIAN‐TU‐001 trial of gantenerumab or solanezumab.

    Published in:
    Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2024, v. 20, n. S8, p. 1, doi. 10.1002/alz.095436
    By:
    • Chen, Charles D.;
    • Franklin, Erin E.;
    • Li, Yan;
    • Joseph‐Mathurin, Nelly;
    • Burns, Aime;
    • Hobbs, Diana A;
    • McCullough, Austin A.;
    • Schultz, Stephanie A.;
    • Wang, Guoqiao;
    • Benzinger, Tammie L.S.;
    • Bateman, Randall J.;
    • Perrin, Richard J.
    Publication type:
    Article
    28

    Safety of higher doses of gantenerumab in the open‐label extension of the DIAN–TU‐001 trial.

    Published in:
    Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2024, v. 20, n. S8, p. 1, doi. 10.1002/alz.094830
    By:
    • Llibre‐Guerra, Jorge J.;
    • Li, Yan;
    • Yen, Daniel;
    • Joseph‐Mathurin, Nelly;
    • Wang, Guoqiao;
    • Aschenbrenner, Andrew J.;
    • Xiong, Chengjie;
    • Hassenstab, Jason J.;
    • Gordon, Brian A.;
    • Benzinger, Tammie L.S.;
    • Perrin, Richard J.;
    • Hofmann, Carsten;
    • Wojtowicz, Jakub;
    • Atri, Alireza;
    • McDade, Eric;
    • Bateman, Randall J.;
    • Clifford, David B.
    Publication type:
    Article
    29

    Evaluating brain age using functional connectivity in autosomal dominant Alzheimer disease.

    Published in:
    Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2024, v. 20, n. S2, p. 1, doi. 10.1002/alz.084990
    By:
    • Macharia, Kiana Angela;
    • Gordon, Brian A.;
    • Wisch, Julie K.;
    • Metcalf, Nicholas V;
    • Roman, June;
    • Benzinger, Tammie L.S.;
    • Cruchaga, Carlos;
    • Goate, Alison M.;
    • Hassenstab, Jason J.;
    • Ibanez, Laura;
    • Karch, Celeste M.;
    • Llibre‐Guerra, Jorge J.;
    • Morris, John C.;
    • Perrin, Richard J.;
    • Renton, Alan E.;
    • Supnet, Charlene B;
    • Xiong, Chengjie;
    • Bateman, Randall J.;
    • McDade, Eric;
    • Ances, Beau
    Publication type:
    Article
    30

    CSF proteomics related to the neurovascular unit are associated with white matter hyperintensity volumes and cerebral microhemorrhages in autosomal dominant Alzheimer disease.

    Published in:
    Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2024, v. 20, n. S2, p. 1, doi. 10.1002/alz.084578
    By:
    • Joseph‐Mathurin, Nelly;
    • Shen, Yuanyuan;
    • Friedrichsen, Karl A.;
    • Chen, Charles D.;
    • McCullough, Austin A.;
    • Strain, Jeremy F.;
    • Shirzadi, Zahra;
    • Chen, Gengsheng;
    • Massoumzadeh, Parinaz;
    • Gordon, Brian A.;
    • Llibre‐Guerra, Jorge J.;
    • Hassenstab, Jason J.;
    • Ibanez, Laura;
    • Lu, Ruijin;
    • Schultz, Stephanie A.;
    • Chhatwal, Jasmeer P.;
    • Morris, John C.;
    • Perrin, Richard J.;
    • An, Hongyu;
    • Xiong, Chengjie
    Publication type:
    Article
    31

    Identification of differentially expressed genes in post‐mortem tissue from African American Alzheimer disease cases and controls.

    Published in:
    Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2024, v. 20, p. 1, doi. 10.1002/alz.091575
    By:
    • Logue, Mark W.;
    • Labadorf, Adam Thomas;
    • O'Neill, Nicholas K;
    • Dickson, Dennis W.;
    • Flanagan, Margaret E;
    • Franklin, Erin E.;
    • Frosch, Matt P.;
    • Gearing, Marla;
    • Jin, Lee‐Way;
    • Kofler, Julia;
    • Lee, Eddie B;
    • Mayeux, Richard;
    • McKee, Ann C.;
    • Miller, Carol A;
    • Murray, Melissa E.;
    • Nelson, Peter T;
    • Perrin, Richard J.;
    • Schneider, Julie A.;
    • Stein, Thor D.;
    • Teich, Andrew F
    Publication type:
    Article
    32

    P‐tau217 significance as marker of brain Abeta and tau pathologies.

    Published in:
    Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2024, v. 20, p. 1, doi. 10.1002/alz.089427
    By:
    • Barthélemy, Nicolas R.;
    • He, Yingxin;
    • Salvadó, Gemma;
    • Janelidze, Shorena;
    • Li, Yan;
    • Ghoshal, Nupur;
    • Mukherjee, Soumya;
    • Horie, Kanta;
    • Spina, Salvatore;
    • VandeVrede, Lawren;
    • Paterson, Ross W.;
    • Perrin, Richard J.;
    • Benzinger, Tammie L.S.;
    • Boxer, Adam L.;
    • Gabelle, Audrey;
    • Sato, Chihiro;
    • Schindler, Suzanne E.;
    • McDade, Eric;
    • Gordon, Brian A.;
    • Hansson, Oskar
    Publication type:
    Article
    33

    Lewy body pathology in autosomal dominant and sporadic Alzheimer's disease – neuropathological distribution patterns and associated survival and genetic findings.

    Published in:
    Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2024, v. 20, p. 1, doi. 10.1002/alz.088905
    By:
    • Vöglein, Jonathan;
    • Ryan, Natalie S;
    • Cruchaga, Carlos;
    • Gorijala, Priyanka;
    • Bateman, Randall J.;
    • McDade, Eric;
    • Paumier, Katrina L.;
    • Cairns, Nigel J;
    • Franklin, Erin E.;
    • Xiong, Chengjie;
    • Jucker, Mathias;
    • Lashley, Tammaryn;
    • Arzberger, Thomas;
    • Herms, Jochen;
    • Perrin, Richard J.;
    • Danek, Adrian;
    • Höglinger, Günter;
    • Morris, John C.;
    • Fox, Nick C;
    • Levin, Johannes
    Publication type:
    Article
    34

    Cognitive reserve influences symptom onset and longitudinal decline in Dominantly Inherited Alzheimer's Disease.

    Published in:
    Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2024, v. 20, p. 1, doi. 10.1002/alz.086295
    By:
    • Llibre‐Guerra, Jorge J.;
    • Lu, Ruijin;
    • Renton, Alan E.;
    • Gordon, Brian A.;
    • Benzinger, Tammie L.S.;
    • Aschenbrenner, Andrew J.;
    • Hassenstab, Jason J.;
    • Xiong, Chengjie;
    • Perrin, Richard J.;
    • Ibanez, Laura;
    • Goate, Alison M.;
    • Cruchaga, Carlos;
    • Morris, John C.;
    • Daniels, Alisha;
    • McDade, Eric;
    • Bateman, Randall J.
    Publication type:
    Article
    35
    36

    Hypertension and cerebral blood flow in the development of Alzheimer's disease.

    Published in:
    Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2024, v. 20, n. 11, p. 7729, doi. 10.1002/alz.14233
    By:
    • Bachmann, Dario;
    • Saake, Antje;
    • Studer, Sandro;
    • Buchmann, Andreas;
    • Rauen, Katrin;
    • Gruber, Esmeralda;
    • Michels, Lars;
    • Nitsch, Roger M.;
    • Hock, Christoph;
    • Gietl, Anton;
    • Treyer, Valerie;
    • Weiner, Michael W.;
    • Trojanowski, John Q.;
    • Shaw, Leslie;
    • Beckett, Laurel;
    • Aisen, Paul;
    • Petersen, Ronald;
    • Morris, John C.;
    • Perrin, Richard J.;
    • Toga, Arthur W.
    Publication type:
    Article
    37

    A cross‐sectional study of α‐synuclein seed amplification assay in Alzheimer's disease neuroimaging initiative: Prevalence and associations with Alzheimer's disease biomarkers and cognitive function.

    Published in:
    Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2024, v. 20, n. 8, p. 5114, doi. 10.1002/alz.13858
    By:
    • Tosun, Duygu;
    • Hausle, Zachary;
    • Iwaki, Hirotaka;
    • Thropp, Pamela;
    • Lamoureux, Jennifer;
    • Lee, Edward B.;
    • MacLeod, Karen;
    • McEvoy, Sean;
    • Nalls, Michael;
    • Perrin, Richard J.;
    • Saykin, Andrew J.;
    • Shaw, Leslie M.;
    • Singleton, Andrew B.;
    • Lebovitz, Russ;
    • Weiner, Michael W.;
    • Blauwendraat, Cornelis
    Publication type:
    Article
    38

    α‐Synuclein seed amplification assay detects Lewy body co‐pathology in autosomal dominant Alzheimer's disease late in the disease course and dependent on Lewy pathology burden.

    Published in:
    Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2024, v. 20, n. 6, p. 4351, doi. 10.1002/alz.13818
    By:
    • Levin, Johannes;
    • Baiardi, Simone;
    • Quadalti, Corinne;
    • Rossi, Marcello;
    • Mammana, Angela;
    • Vöglein, Jonathan;
    • Bernhardt, Alexander;
    • Perrin, Richard J.;
    • Jucker, Mathias;
    • Preische, Oliver;
    • Hofmann, Anna;
    • Höglinger, Günter U.;
    • Cairns, Nigel J.;
    • Franklin, Erin E.;
    • Chrem, Patricio;
    • Cruchaga, Carlos;
    • Berman, Sarah B.;
    • Chhatwal, Jasmeer P.;
    • Daniels, Alisha;
    • Day, Gregory S.
    Publication type:
    Article
    39

    Alzheimer's polygenic risk scores are associated with cognitive phenotypes in Down syndrome.

    Published in:
    Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2024, v. 20, n. 2, p. 1038, doi. 10.1002/alz.13506
    By:
    • Gorijala, Priyanka;
    • Aslam, M. Muaaz;
    • Dang, Lam‐Ha T.;
    • Xicota, L.;
    • Fernandez, Maria V.;
    • Sung, Yun Ju;
    • Fan, Kang‐Hsien;
    • Feingold, Eleanor;
    • Surace, Ezequiel I.;
    • Chhatwal, Jasmeer P;
    • Hom, Christy L.;
    • Hartley, Sigan L.;
    • Hassenstab, Jason;
    • Perrin, Richard J.;
    • Mapstone, Mark;
    • Zaman, Shahid H;
    • Ances, Beau M;
    • Kamboh, M. Ilyas;
    • Lee, Joseph H;
    • Cruchaga, Carlos
    Publication type:
    Article
    40

    Investigation of sex differences in mutation carriers of the Dominantly Inherited Alzheimer Network.

    Published in:
    Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2024, v. 20, n. 1, p. 47, doi. 10.1002/alz.13460
    By:
    • Wagemann, Olivia;
    • Li, Yan;
    • Hassenstab, Jason;
    • Aschenbrenner, Andrew J.;
    • McKay, Nicole S.;
    • Gordon, Brian A.;
    • Benzinger, Tammie L. S.;
    • Xiong, Chengjie;
    • Cruchaga, Carlos;
    • Renton, Alan E.;
    • Perrin, Richard J.;
    • Berman, Sarah B.;
    • Chhatwal, Jasmeer P.;
    • Farlow, Martin R.;
    • Day, Gregory S.;
    • Ikeuchi, Takeshi;
    • Jucker, Mathias;
    • Lopera, Francisco;
    • Mori, Hiroshi;
    • Noble, James M.
    Publication type:
    Article
    41

    The Alzheimer's Disease Neuroimaging Initiative in the era of Alzheimer's disease treatment: A review of ADNI studies from 2021 to 2022.

    Published in:
    Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2024, v. 20, n. 1, p. 652, doi. 10.1002/alz.13449
    By:
    • Veitch, Dallas P.;
    • Weiner, Michael W.;
    • Miller, Melanie;
    • Aisen, Paul S.;
    • Ashford, Miriam A.;
    • Beckett, Laurel A.;
    • Green, Robert C.;
    • Harvey, Danielle;
    • Jack, Clifford R.;
    • Jagust, William;
    • Landau, Susan M.;
    • Morris, John C.;
    • Nho, Kwangsik T.;
    • Nosheny, Rachel;
    • Okonkwo, Ozioma;
    • Perrin, Richard J.;
    • Petersen, Ronald C.;
    • Rivera Mindt, Monica;
    • Saykin, Andrew;
    • Shaw, Leslie M.
    Publication type:
    Article
    42
    43

    Functional variations in gamma‐secretase processing of APP are critical determinants of the clinical, biomarker, and cognitive progression of autosomal dominant Alzheimer's disease.

    Published in:
    Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2023, v. 19, p. 1, doi. 10.1002/alz.082318
    By:
    • Schultz, Stephanie A.;
    • Liu, Lei;
    • Schultz, Aaron P.;
    • Fitzpatrick, Colleen D;
    • Levin, Raina;
    • Bellier, Jean‐Pierre;
    • Shirzadi, Zahra;
    • Joseph‐Mathurin, Nelly;
    • Chen, Charles D.;
    • Benzinger, Tammie L.S.;
    • Day, Gregory S.;
    • Farlow, Martin R.;
    • Hassenstab, Jason J.;
    • Jack, Clifford R.;
    • Jucker, Mathias;
    • Lee, Jae‐Hong;
    • Levin, Johannes;
    • Perrin, Richard J.;
    • Schofield, Peter W.;
    • Karch, Celeste M.
    Publication type:
    Article
    44
    45

    Investigation of sex differences in mutation carriers of the Dominantly Inherited Alzheimer Network.

    Published in:
    Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2023, v. 19, p. 1, doi. 10.1002/alz.071752
    By:
    • Wagemann, Olivia;
    • Li, Yan;
    • Hassenstab, Jason J.;
    • Aschenbrenner, Andrew J.;
    • Benzinger, Tammie L.S.;
    • Gordon, Brian A.;
    • Wang, Guoqiao;
    • Karch, Celeste M.;
    • Renton, Alan E.;
    • Cruchaga, Carlos;
    • Morris, John C;
    • Xiong, Chengjie;
    • Perrin, Richard J.;
    • Levin, Johannes;
    • Daniels, Alisha;
    • Bateman, Randall J.;
    • McDade, Eric;
    • Llibre‐Guerra, Jorge J
    Publication type:
    Article
    46

    Evaluating brain age as a marker of autosomal dominant Alzheimer disease progression.

    Published in:
    Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2023, v. 19, p. 1, doi. 10.1002/alz.070790
    By:
    • Millar, Peter R;
    • Gordon, Brian A.;
    • Benzinger, Tammie L.S.;
    • Cruchaga, Carlos;
    • Fagan, Anne M.;
    • Goate, Alison;
    • Hassenstab, Jason J.;
    • Holtzman, David M.;
    • Llibre‐Guerra, Jorge J;
    • Morris, John C;
    • Perrin, Richard J.;
    • Supnet, Charlene B;
    • Xiong, Chengjie;
    • Bateman, Randall J.;
    • Ances, Beau;
    • McDade, Eric
    Publication type:
    Article
    47
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    Is Levodopa Response a Valid Indicator of Parkinson's Disease?

    Published in:
    Movement Disorders, 2021, v. 36, n. 4, p. 948, doi. 10.1002/mds.28406
    By:
    • Martin, W.R. Wayne;
    • Miles, Michael;
    • Zhong, Qiaonan;
    • Hartlein, Johanna;
    • Racette, Brad A.;
    • Norris, Scott A.;
    • Ushe, Mwiza;
    • Maiti, Baijayanta;
    • Criswell, Susan;
    • Davis, Albert A.;
    • Kotzbauer, Paul T.;
    • Cairns, Nigel J.;
    • Perrin, Richard J.;
    • Perlmutter, Joel S.
    Publication type:
    Article