Works by Perks, Claire M.

Results: 49

Blood lipids and prostate cancer: a Mendelian randomization analysis.

Published in:

Cancer Medicine, 2016, v. 5, n. 6, p. 1125, doi. 10.1002/cam4.695

By:

Bull, Caroline J.;
Bonilla, Carolina;
Holly, Jeff M. P.;
Perks, Claire M.;
Davies, Neil;
Haycock, Philip;
Yu, Oriana Hoi Yun;
Richards, J. Brent;
Eeles, Rosalind;
Easton, Doug;
Kote ‐ Jarai, Zsofia;
Amin Al Olama, Ali;
Benlloch, Sara;
Muir, Kenneth;
Giles, Graham G.;
MacInnis, Robert J.;
Wiklund, Fredrik;
Gronberg, Henrik;
Haiman, Christopher A.;
Schleutker, Johanna

Publication type:

Article

A Role for ER-Beta in the Effects of Low-Density Lipoprotein Cholesterol and 27-Hydroxycholesterol on Breast Cancer Progression: Involvement of the IGF Signalling Pathway?

Published in:

Cells (2073-4409), 2022, v. 11, n. 1, p. 94, doi. 10.3390/cells11010094

By:

Mashat, Reham M.;
Zielinska, Hanna A.;
Holly, Jeff M. P.;
Perks, Claire M.

Publication type:

Article

The Neglected Insulin: IGF-II, a Metabolic Regulator with Implications for Diabetes, Obesity, and Cancer.

Published in:

Cells (2073-4409), 2019, v. 8, n. 10, p. 1207, doi. 10.3390/cells8101207

By:

Holly, Jeff M. P.;
Biernacka, Kalina;
Perks, Claire M.

Publication type:

Article

Glioma Stem-Like Cells and Metabolism: Potential for Novel Therapeutic Strategies.

Published in:

Frontiers in Oncology, 2021, v. 11, p. 1, doi. 10.3389/fonc.2021.743814

By:

Harland, Abigail;
Liu, Xia;
Ghirardello, Mattia;
Galan, M. Carmen;
Perks, Claire M.;
Kurian, Kathreena M.

Publication type:

Article

Editorial: Insights in cancer endocrinology: 2022.

Published in:

Frontiers in Endocrinology, 2023, p. 1, doi. 10.3389/fendo.2023.1236887

By:

Perks, Claire M.;
Belfiore, Antonino

Publication type:

Article

Could Reducing Body Fatness Reduce the Risk of Aggressive Prostate Cancer via the Insulin Signalling Pathway? A Systematic Review of the Mechanistic Pathway.

Published in:

Metabolites (2218-1989), 2021, v. 11, n. 11, p. 726, doi. 10.3390/metabo11110726

By:

James, Rachel;
Dimopoulou, Olympia;
Martin, Richard M.;
Perks, Claire M.;
Kelly, Claire;
Mathias, Louise;
Brugger, Stefan;
Higgins, Julian P. T.;
Lewis, Sarah J.

Publication type:

Article

Insulin Receptor Isoform Variations in Prostate Cancer Cells.

Published in:

Frontiers in Endocrinology, 2016, p. 1, doi. 10.3389/fendo.2016.00132

By:

Perks, Claire M.;
Zielinska, H. A.;
Jing Wang;
Jarrett, Caroline;
Frankow, A.;
Holly, Jeff M. P.;
Ladomery, Michael R.;
Bahl, Amit;
Rhodes, Anthony;
Oxley, Jon

Publication type:

Article

Effects of physiological levels of the green tea extract epigallocatechin-3-gallate on breast cancer cells.

Published in:

Frontiers in Endocrinology, 2014, v. 5, p. 1, doi. 10.3389/fendo.2014.00061

By:

Li Zeng;
Holly, Jeff M. P.;
Perks, Claire M.

Publication type:

Article

Effects of physiological levels of the green tea extract Epigallocatechin gallate (EGCG) on breast cancer cells.

Published in:

Frontiers in Endocrinology, 2014, v. 5, p. 1, doi. 10.3389/fendo.2014.00061

By:

Li Zeng;
Holly, Jeff M. P.;
Perks, Claire M.

Publication type:

Article

Grand challenges in cancer endocrinology: endocrine related cancers, an expanding concept.

Published in:

Frontiers in Endocrinology, 2013, v. 4, p. 1, doi. 10.3389/fendo.2013.00141

By:

Belfiore, Antonino;
Perks, Claire M.

Publication type:

Article

Epithelial-to-mesenchymal transition in breast cancer: a role for insulin-like growth factor I and insulin-like growth factor-binding protein 3?

Published in:

Breast Cancer: Targets & Therapy, 2015, v. 7, p. 9, doi. 10.2147/BCTT.S43932

By:

Zielinska, Hanna A.;
Bahl, Amit;
Holly, Jeff MP;
Perks, Claire M.

Publication type:

Article

Mini-Review: Current Bladder Cancer Treatment—The Need for Improvement.

Published in:

International Journal of Molecular Sciences, 2024, v. 25, n. 3, p. 1557, doi. 10.3390/ijms25031557

By:

Gill, Emily;
Perks, Claire M.

Publication type:

Article

Role of the Insulin-like Growth Factor (IGF) Axis in Diseases.

Published in:

International Journal of Molecular Sciences, 2023, v. 24, n. 23, p. 16969, doi. 10.3390/ijms242316969

By:

Perks, Claire M.

Publication type:

Article

The Sirenic Links between Diabetes, Obesity, and Bladder Cancer.

Published in:

International Journal of Molecular Sciences, 2021, v. 22, n. 20, p. 11150, doi. 10.3390/ijms222011150

By:

Gill, Emily;
Sandhu, Gurimaan;
Ward, Douglas G.;
Perks, Claire M.;
Bryan, Richard T.

Publication type:

Article

Lessons to Learn for Adequate Targeted Therapy Development in Metastatic Colorectal Cancer Patients.

Published in:

International Journal of Molecular Sciences, 2021, v. 22, n. 9, p. 5019, doi. 10.3390/ijms22095019

By:

Oliveres, Helena;
Pesántez, David;
Maurel, Joan;
Perks, Claire M.;
Kuppen, Peter J. K.

Publication type:

Article

The Role of IGF/IGF-1R Signaling in Hepatocellular Carcinomas: Stemness-Related Properties and Drug Resistance.

Published in:

International Journal of Molecular Sciences, 2021, v. 22, n. 4, p. 1931, doi. 10.3390/ijms22041931

By:

Ngo, Mai-Huong Thi;
Jeng, Han-Yin;
Kuo, Yung-Che;
Nanda, Josephine Diony;
Brahmadhi, Ageng;
Ling, Thai-Yen;
Chang, Te-Sheng;
Huang, Yen-Hua;
Perks, Claire M.

Publication type:

Article

Glucose Concentration in Cell Culture Medium Influences the BRCA1-Mediated Regulation of the Lipogenic Action of IGF-I in Breast Cancer Cells.

Published in:

International Journal of Molecular Sciences, 2020, v. 21, n. 22, p. 8674, doi. 10.3390/ijms21228674

By:

Koobotse, Moses O.;
Schmidt, Dayane;
Holly, Jeff M. P.;
Perks, Claire M.

Publication type:

Article

Evaluating circulating tumour cell enrichment techniques to establish an appropriate method for clinical application in glioblastomas.

Published in:

Frontiers in Neurology, 2024, p. 1, doi. 10.3389/fneur.2024.1358531

By:

Barber, Hannah R.;
Perks, Claire M.;
Kurian, Kathreena M.

Publication type:

Article

Untangling the role of tau in sex hormone responsive cancers: lessons learnt from Alzheimer's disease.

Published in:

Clinical Science, 2024, v. 138, n. 21, p. 1357, doi. 10.1042/CS20230317

By:

Barker, Rachel M.;
Chambers, Alfie;
Kehoe, Patrick G.;
Rowe, Edward;
Perks, Claire M.

Publication type:

Article

Fibronectin confers survival against chemotherapeutic agents but not against radiotherapy in DU145 prostate cancer cells: Involvement of the insulin like growth factor-1 receptor.

Published in:

Prostate, 2010, v. 70, n. 8, p. 856, doi. 10.1002/pros.21119

By:

Thomas, Francis;
Holly, Jeff M.P.;
Persad, Raj;
Bahl, Amit;
Perks, Claire M.

Publication type:

Article

Dihydrotestosterone sensitises LNCaP cells to death induced by epigallocatechin-3-gallate (EGCG) or an IGF-i receptor inhibitor.

Published in:

Prostate, 2009, v. 69, n. 2, p. 219, doi. 10.1002/pros.20873

By:

Thomas, Francis;
Patel, Suril;
Holly, Jeff M.P.;
Persad, Raj;
Bahl, Amit;
Perks, Claire M.

Publication type:

Article

Differential IGF-independent effects of insulin-like growth factor binding proteins (1-6) on apoptosis of breast epithelial cells.

Published in:

Journal of Cellular Biochemistry, 1999, v. 75, n. 4, p. 652, doi. 10.1002/(SICI)1097-4644(19991215)75:4<652::AID-JCB11>3.0.CO;2-0

By:

Perks, Claire M.;
Bowen, Samantha;
Gill, Zahidah P.;
Newcomb, Paul V.;
Holly, Jeff M.P.

Publication type:

Article

PTEN-mediated pathways and their association with treatment-resistant prostate cancer.

Published in:

BJU International, 2009, v. 104, n. 4, p. 556, doi. 10.1111/j.1464-410X.2009.08411.x

By:

Uzoh, Christopher C.;
Perks, Claire M.;
Bahl, Amit;
Holly, Jeff M.P.;
Sugiono, Marto;
Persad, Raj A.

Publication type:

Article

DNA damage uncouples the mitogenic response to IGF-I in MCF-7 malignant breast cancer cells by switching the roles of PI3 kinase and p21.

Published in:

International Journal of Cancer, 2005, v. 116, n. 4, p. 506, doi. 10.1002/ijc.21029

By:

Clark, Martin A.;
Perks, Claire M.;
Winters, Zoë E.;
Holly, Jeff M.P.

Publication type:

Article

IGFBp-3 prolongs the p53 response and enhances apoptosis following UV irradiation.

Published in:

International Journal of Cancer, 2000, v. 88, n. 3, p. 336, doi. 10.1002/1097-0215(20001101)88:3<336::AID-IJC3>3.0.CO;2-A

By:

Hollowood, Andrew D.;
Lai, Teresa;
Perks, Claire M.;
Newcomb, Paul V.;
Alderson, Derek;
Holly, Jeff M.P.

Publication type:

Article

Changes in the levels of integrin and focal adhesion kinase (FAK) in human melanoma cells following 532 nm laser treatment.

Published in:

International Journal of Cancer, 1999, v. 82, n. 3, p. 353, doi. 10.1002/(SICI)1097-0215(19990730)82:3<353::AID-IJC8>3.0.CO;2-4

By:

Zhu, Ning Wen;
Perks, Claire M.;
Burd, Andrew R.;
Holly, Jeff M.P.

Publication type:

Article

Editorial: insights in cancer endocrinology 2021.

Published in:

Frontiers in Endocrinology, 2022, v. 13, p. 1, doi. 10.3389/fendo.2022.987764

By:

Perks, Claire M.;
Belfiore, Antonino

Publication type:

Article

Editorial: Women in endocrinology 2021.

Published in:

Frontiers in Endocrinology, 2022, v. 13, p. 1, doi. 10.3389/fendo.2022.987727

By:

Perks, Claire M.;
Radovick, Sally;
Samaras, Katherine

Publication type:

Article

Editorial: The Role of the IGF/Insulin-IGFBP Axis in Normal Physiology and Disease.

Published in:

Frontiers in Endocrinology, 2022, v. 13, p. 1, doi. 10.3389/fendo.2022.892140

By:

Takahashi, Shin-Ichiro;
Perks, Claire M.

Publication type:

Article

Alteration of Metabolic Conditions Impacts the Regulation of IGF-II/H19 Imprinting Status in Prostate Cancer.

Published in:

Cancers, 2021, v. 13, n. 4, p. 825, doi. 10.3390/cancers13040825

By:

Kingshott, Georgina;
Biernacka, Kalina;
Sewell, Alex;
Gwiti, Paida;
Barker, Rachel;
Zielinska, Hanna;
Gilkes, Amanda;
McCarthy, Kathryn;
Martin, Richard M.;
Lane, J. Athene;
McGeagh, Lucy;
Koupparis, Anthony;
Rowe, Edward;
Oxley, Jon;
Holly, Jeff M. P.;
Perks, Claire M.

Publication type:

Article

Interaction between GRP78 and IGFBP-3 Affects Tumourigenesis and Prognosis in Breast Cancer Patients.

Published in:

Cancers, 2020, v. 12, n. 12, p. 3821, doi. 10.3390/cancers12123821

By:

Zielinska, Hanna A.;
Daly, Carl S.;
Alghamdi, Ahmad;
Bahl, Amit;
Sohail, Muhammed;
White, Paul;
Dean, Sarah R.;
Holly, Jeff M. P.;
Perks, Claire M.

Publication type:

Article

IGFBP-1 expression is reduced in human type 2 diabetic glomeruli and modulates β1-integrin/FAK signalling in human podocytes.

Published in:

Diabetologia, 2021, v. 64, n. 7, p. 1690, doi. 10.1007/s00125-021-05427-1

By:

Lay, Abigail C.;
Hale, Lorna J.;
Stowell-Connolly, Holly;
Pope, Robert J. P.;
Nair, Viji;
Ju, Wenjun;
Marquez, Eva;
Rollason, Ruth;
Hurcombe, Jenny A.;
Hayes, Bryony;
Roberts, Timothy;
Gillam, Lawrence;
Allington, Jonathan;
Nelson, Robert G.;
Kretzler, Matthias;
Holly, Jeff M. P.;
Perks, Claire M.;
McArdle, Craig A.;
Welsh, Gavin I.;
Coward, Richard J. M.

Publication type:

Article

Insulin‐like growth factor binding protein‐2 and glucose‐regulated protein 78 kDa: Potential biomarkers affect prognosis in IDH‐wildtype glioblastoma patients.

Published in:

Cancer Medicine, 2023, v. 12, n. 13, p. 14426, doi. 10.1002/cam4.6071

By:

Harland, Abigail J.;
Perks, Claire M.;
White, Paul;
Kurian, Kathreena M.;
Barber, Hannah R.

Publication type:

Article

Obesity, Diabetes and COVID-19: An Infectious Disease Spreading From the East Collides With the Consequences of an Unhealthy Western Lifestyle.

Published in:

Frontiers in Endocrinology, 2020, v. 11, p. N.PAG, doi. 10.3389/fendo.2020.582870

By:

Holly, Jeff M. P.;
Biernacka, Kalina;
Maskell, Nick;
Perks, Claire M.

Publication type:

Article

Mini Review: Opposing Pathologies in Cancer and Alzheimer's Disease: Does the PI3K/Akt Pathway Provide Clues?

Published in:

Frontiers in Endocrinology, 2020, v. 11, p. 1, doi. 10.3389/fendo.2020.00403

By:

Barker, Rachel M.;
Holly, Jeff M. P.;
Biernacka, Kalina M.;
Allen-Birt, Shelley J.;
Perks, Claire M.

Publication type:

Article

Prostate cancer - evidence of exercise and nutrition trial (PrEvENT): study protocol for a randomised controlled feasibility trial.

Published in:

2016

By:

Hackshaw-McGeagh, Lucy;
Lane, J. Athene;
Persad, Raj;
Gillatt, David;
Holly, Jeff M. P.;
Koupparis, nthony;
Rowe, Edward;
Johnston, Lyndsey;
Cloete, Jenny;
Shiridzinomwa, Constance;
Abrams, Paul;
Penfold, Chris M.;
Bahl, Amit;
Oxley, Jon;
Perks, Claire M.;
Martin, Richard;
Koupparis, Anthony

Publication type:

journal article

The Role of Insulin-like Growth Factor Binding Protein (IGFBP)-2 in DNA Repair and Chemoresistance in Breast Cancer Cells.

Published in:

Cancers, 2024, v. 16, n. 11, p. 2113, doi. 10.3390/cancers16112113

By:

Mohammedali, Alaa;
Biernacka, Kalina;
Barker, Rachel M.;
Holly, Jeff M. P.;
Perks, Claire M.

Publication type:

Article

Association between genetically proxied PCSK9 inhibition and prostate cancer risk: A Mendelian randomisation study.

Published in:

PLoS Medicine, 2023, v. 19, n. 1, p. 1, doi. 10.1371/journal.pmed.1003988

By:

Fang, Si;
Yarmolinsky, James;
Gill, Dipender;
Bull, Caroline J.;
Perks, Claire M.;
Davey Smith, George;
Gaunt, Tom R.;
Richardson, Tom G.

Publication type:

Article

CDC2-like (CLK) protein kinase inhibition as a novel targeted therapeutic strategy in prostate cancer.

Published in:

Scientific Reports, 2021, v. 11, n. 1, p. 1, doi. 10.1038/s41598-021-86908-6

By:

Uzor, Simon;
Porazinski, Sean R.;
Li, Ling;
Clark, Bethany;
Ajiro, Masahiko;
Iida, Kei;
Hagiwara, Masatoshi;
Alqasem, Abdullah A.;
Perks, Claire M.;
Wilson, Ian D.;
Oltean, Sebastian;
Ladomery, Michael R.

Publication type:

Article

Systemic Metabolism, Its Regulators, and Cancer: Past Mistakes and Future Potential.

Published in:

Frontiers in Endocrinology, 2019, p. N.PAG, doi. 10.3389/fendo.2019.00065

By:

Holly, Jeff M. P.;
Biernacka, Kalina;
Perks, Claire M.

Publication type:

Article

IGFBP-2 and IGF-II: Key Components of the Neural Stem Cell Niche? Implications for Glioblastoma Pathogenesis.

Published in:

International Journal of Molecular Sciences, 2025, v. 26, n. 10, p. 4749, doi. 10.3390/ijms26104749

By:

Harland, Abigail J.;
Perks, Claire M.

Publication type:

Article

Epithelial cancers in the post-genomic era: should we reconsider our lifestyle?

Published in:

Cancer & Metastasis Reviews, 2013, v. 32, n. 3/4, p. 673, doi. 10.1007/s10555-013-9445-5

By:

Holly, Jeff M. P.;
Zeng, Li;
Perks, Claire M.

Publication type:

Article

The Insulin-Like Growth Factor (IGF) Family and Breast Cancer.

Published in:

Breast Disease, 2003, v. 18, n. 1, p. 45, doi. 10.3233/BD-2003-18106

By:

Perks, Claire M.;
Holly, Jeff M. P.

Publication type:

Article

IGFBPs and Breast Cancer.

Published in:

Breast Disease, 2003, v. 17, n. 1, p. 91, doi. 10.3233/BD-2003-17109

By:

Perks, Claire M.;
Holly, Jeff M. P.

Publication type:

Article

Curious Dichotomies of Apolipoprotein E Function in Alzheimer's Disease and Cancer—One Explanatory Mechanism of Inverse Disease Associations?

Published in:

Genes, 2025, v. 16, n. 3, p. 331, doi. 10.3390/genes16030331

By:

Perks, Claire M.;
Barker, Rachel M.;
Alhadrami, Mai;
Alkahtani, Omar;
Gill, Emily;
Grishaw, Mary;
Harland, Abigail J.;
Henley, Peter;
Li, Haonan;
O'Sullivan, Ellie;
Stone, Gideon;
Su, Xiaoyu;
Kehoe, Patrick G.

Publication type:

Article

Loss of PTEN Expression Is Associated With IGFBP2 Expression, Younger Age, and Late Stage in Triple-Negative Breast Cancer.

Published in:

American Journal of Clinical Pathology, 2014, v. 141, n. 3, p. 323, doi. 10.1309/AJCPR11DEAYPTUSL

By:

Dean, Sarah J. R.;
Perks, Claire M.;
Holly, Jeff M. P.;
Bhoo-Pathy, Nirmala;
Lai-Meng Looi;
Taib Mohammed, Nur Aishah;
Koobotse, Moses O.;
Soo-Hwang Teo;
Kein-Seong Mun;
Cheng-Har Yip;
Rhodes, Anthony

Publication type:

Article

The role of insulin-like growth factors in the development of prostate cancer.

Published in:

Expert Review of Endocrinology & Metabolism, 2020, v. 15, n. 4, p. 237, doi. 10.1080/17446651.2020.1764844

By:

Holly, Jeff M. P.;
Biernacka, Kalina;
Perks, Claire M.

Publication type:

Article

How growth hormone may be linked to cancer: concerns and perspective.

Published in:

Expert Review of Endocrinology & Metabolism, 2007, v. 2, n. 6, p. 759, doi. 10.1586/17446651.2.6.759

By:

Holly, Jeff M. P.;
Foulstone, Emily J.;
Perks, Claire M.

Publication type:

Article

Hyperglycemia Promotes TMPRSS2-ERG Gene Fusion in Prostate Cancer Cells via Upregulating Insulin-Like Growth Factor-Binding Protein-2.

Published in:

Frontiers in Endocrinology, 2017, p. 1, doi. 10.3389/fendo.2017.00305

By:

Holly, Jeff M. P.;
Broadhurst, Jessica;
Mansor, Rehanna;
Bahl, Amit;
Perks, Claire M.

Publication type:

Article