Works matching AU Perkins, Emma M.

Results: 11

β-III Spectrin Is Critical for Development of Purkinje Cell Dendritic Tree and Spine Morphogenesis.

Published in:

Journal of Neuroscience, 2011, v. 31, n. 46, p. 16581, doi. 10.1523/JNEUROSCI.3332-11.2011

By:

Yuanzheng Gao;
Perkins, Emma M.;
Clarkson, Yvonne L.;
Tobia, Steven;
Lyndon, Alastair R.;
Jackson, Mandy;
Rothstein, Jeffrey D.

Publication type:

Article

Loss of β-III Spectrin Leads to Purkinje Cell Dysfunction Recapitulating the Behavior and Neuropathology of Spinocerebellar Ataxia Type 5 in Humans.

Published in:

Journal of Neuroscience, 2010, v. 30, n. 14, p. 4857, doi. 10.1523/JNEUROSCI.6065-09.2010

By:

Perkins, Emma M.;
Clarkson, Yvonne L.;
Sabatier, Nancy;
Longhurst, David M.;
Millward, Christopher P.;
Jack, Jennifer;
Toraiwa, Junko;
Watanabe, Mitsunori;
Rothstein, Jeffrey D.;
Lyndon, Alastair R.;
Wyllie, David J. A.;
Dutia, Mayank B.;
Jackson, Mandy

Publication type:

Article

Control of synaptic vesicle endocytosis by an extracellular signalling molecule.

Published in:

Nature Communications, 2013, v. 4, n. 9, p. 2394, doi. 10.1038/ncomms3394

By:

Smillie, Karen J.;
Pawson, Jonathan;
Perkins, Emma M.;
Jackson, Mandy;
Cousin, Michael A.

Publication type:

Article

C9ORF72 repeat expansion causes vulnerability of motor neurons to Ca<sup>2+</sup>-permeable AMPA receptor-mediated excitotoxicity.

Published in:

Nature Communications, 2018, v. 9, n. 1, p. 1, doi. 10.1038/s41467-017-02729-0

By:

Selvaraj, Bhuvaneish T.;
Livesey, Matthew R.;
Chen Zhao;
Gregory, Jenna M.;
James, Owain T.;
Cleary, Elaine M.;
Chouhan, Amit K.;
Gane, Angus B.;
Perkins, Emma M.;
Dando, Owen;
Lillico, Simon G.;
Youn-Bok Lee;
Nishimura, Agnes L.;
Poreci, Urjana;
Thankamony, Sai;
Pray, Meryll;
Vasistha, Navneet A.;
Magnani, Dario;
Borooah, Shyamanga;
Burr, Karen

Publication type:

Article

De novo point mutations in patients diagnosed with ataxic cerebral palsy.

Published in:

2015

By:

Schnekenberg, Ricardo Parolin;
Perkins, Emma M.;
Miller, Jack W.;
Davies, Wayne I. L.;
D'Adamo, Maria Cristina;
Pessia, Mauro;
Fawcett, Katherine A.;
Sims, David;
Gillard, Elodie;
Hudspith, Karl;
Skehel, Paul;
Williams, Jonathan;
O'Regan, Mary;
Jayawant, Sandeep;
Jefferson, Rosalind;
Hughes, Sarah;
Lustenberger, Andrea;
Ragoussis, Jiannis;
Jackson, Mandy;
Tucker, Stephen J.

Publication type:

journal article

Altered network properties in C9ORF72 repeat expansion cortical neurons are due to synaptic dysfunction.

Published in:

Molecular Neurodegeneration, 2021, v. 16, n. 1, p. 1, doi. 10.1186/s13024-021-00433-8

By:

Perkins, Emma M.;
Burr, Karen;
Banerjee, Poulomi;
Mehta, Arpan R.;
Dando, Owen;
Selvaraj, Bhuvaneish T.;
Suminaite, Daumante;
Nanda, Jyoti;
Henstridge, Christopher M.;
Gillingwater, Thomas H.;
Hardingham, Giles E.;
Wyllie, David J. A.;
Chandran, Siddharthan;
Livesey, Matthew R.

Publication type:

Article

Transactive response DNA-binding protein-43 proteinopathy in oligodendrocytes revealed using an induced pluripotent stem cell model.

Published in:

Brain Communications, 2021, v. 3, n. 4, p. 1, doi. 10.1093/braincomms/fcab255

By:

Barton, Samantha K.;
Magnani, Dario;
James, Owen G.;
Livesey, Matthew R.;
Selvaraj, Bhuvaneish T.;
James, Owain T.;
Perkins, Emma M.;
Gregory, Jenna M.;
Cleary, Elaine;
Ausems, C. Rosanne M.;
Carter, Roderick N.;
Vasistha, Navneet A.;
Chen Zhao;
Burr, Karen;
Story, David;
Cardinali, Alessandra;
Morton, Nicholas M.;
Hardingham, Giles E.;
Wyllie, David J. A.;
Chandran, Siddharthan

Publication type:

Article

Posterior cerebellar Purkinje cells in an SCA5/SPARCA1 mouse model are especially vulnerable to the synergistic effect of loss of β-III spectrin and GLAST.

Published in:

Human Molecular Genetics, 2016, v. 25, n. 20, p. 4448, doi. 10.1093/hmg/ddw274

By:

Perkins, Emma M.;
Suminaite, Daumante;
Clarkson, Yvonne L.;
Sin Kwan Lee;
Lyndon, Alastair R.;
Rothstein, Jeffrey D.;
Wyllie, David J. A.;
Kohichi Tanaka;
Jackson, Mandy

Publication type:

Article

β-III spectrin underpins ankyrin R function in Purkinje cell dendritic trees: protein complex critical for sodium channel activity is impaired by SCA5-associated mutations.

Published in:

Human Molecular Genetics, 2014, v. 23, n. 14, p. 3875, doi. 10.1093/hmg/ddu103

By:

Clarkson, Yvonne L.;
Perkins, Emma M.;
Cairncross, Callum J.;
Lyndon, Alastair R.;
Skehel, Paul A.;
Jackson, Mandy

Publication type:

Article

β-III spectrin mutation L253P associated with spinocerebellar ataxia type 5 interferes with binding to Arp1 and protein trafficking from the Golgi.

Published in:

Human Molecular Genetics, 2010, v. 19, n. 18, p. 3634, doi. 10.1093/hmg/ddq279

By:

Clarkson, Yvonne L.;
Gillespie, Trudi;
Perkins, Emma M.;
Lyndon, Alastair R.;
Jackson, Mandy

Publication type:

Article

A TASK-like pH- and amine-sensitive‘leak’ K<sup>+</sup> conductance regulates neonatal rat facial motoneuron excitabilityin vitro.

Published in:

European Journal of Neuroscience, 2005, v. 21, n. 3, p. 679, doi. 10.1111/j.1460-9568.2005.03898.x

By:

Larkman, Philip M.;
Perkins, Emma M.

Publication type:

Article