Works by Pereira de Almeida, Luís

Results: 64

Caffeine alleviates progressive motor deficits in a transgenic mouse model of spinocerebellar ataxia.

Published in:

2017

By:

Gonçalves, Nélio;
Simões, Ana T.;
Prediger, Rui D.;
Hirai, Hirokazu;
Cunha, Rodrigo A.;
Pereira de Almeida, Luís;
Gonçalves, Nélio;
Simões, Ana T;
Pereira de Almeida, Luís

Publication type:

journal article

Neuropeptide Y Enhances Progerin Clearance and Ameliorates the Senescent Phenotype of Human Hutchinson-Gilford Progeria Syndrome Cells.

Published in:

2020

By:

Aveleira, Célia A;
Ferreira-Marques, Marisa;
Cortes, Luísa;
Valero, Jorge;
Pereira, Dina;
Almeida, Luís Pereira de;
Cavadas, Cláudia;
Pereira de Almeida, Luís

Publication type:

journal article

Re-establishing ataxin-2 downregulates translation of mutant ataxin-3 and alleviates Machado-Joseph disease.

Published in:

2015

By:

Nóbrega, Clévio;
Carmo-Silva, Sara;
Albuquerque, David;
Vasconcelos-Ferreira, Ana;
Vijayakumar, Udaya-Geetha;
Mendonça, Liliana;
Hirai, Hirokazu;
de Almeida, Luís Pereira;
Pereira de Almeida, Luís

Publication type:

journal article

Ghrelin delays premature aging in Hutchinson‐Gilford progeria syndrome.

Published in:

Aging Cell, 2023, v. 22, n. 12, p. 1, doi. 10.1111/acel.13983

By:

Ferreira‐Marques, Marisa;
Carvalho, André;
Franco, Ana Catarina;
Leal, Ana;
Botelho, Mariana;
Carmo‐Silva, Sara;
Águas, Rodolfo;
Cortes, Luísa;
Lucas, Vasco;
Real, Ana Carolina;
López‐Otín, Carlos;
Nissan, Xavier;
de Almeida, Luís Pereira;
Cavadas, Cláudia;
Aveleira, Célia A.

Publication type:

Article

Graft-derived neurons and bystander effects are maintained for six months after human iPSC-derived NESC transplantation in mice's cerebella.

Published in:

Scientific Reports, 2024, v. 14, n. 1, p. 1, doi. 10.1038/s41598-024-53542-x

By:

Mendonça, Liliana S.;
Henriques, Daniel;
Fernandes, Vanessa;
Moreira, Ricardo;
Brás, João;
Duarte, Sónia;
Schwamborn, Jens C.;
de Almeida, Luís Pereira

Publication type:

Article

Successes and Hurdles in Stem Cells Application and Production for Brain Transplantation.

Published in:

Frontiers in Neuroscience, 2019, v. 13, p. 1, doi. 10.3389/fnins.2019.01194

By:

Henriques, Daniel;
Moreira, Ricardo;
Schwamborn, Jens;
Pereira de Almeida, Luís;
Mendonça, Liliana S.

Publication type:

Article

Stage‐Dependent Biomarker Changes in Spinocerebellar Ataxia Type 3.

Published in:

Annals of Neurology, 2024, v. 95, n. 2, p. 400, doi. 10.1002/ana.26824

By:

Faber, Jennifer;
Berger, Moritz;
Wilke, Carlo;
Hubener‐Schmid, Jeannette;
Schaprian, Tamara;
Santana, Magda M.;
Grobe‐Einsler, Marcus;
Onder, Demet;
Koyak, Berkan;
Giunti, Paola;
Garcia‐Moreno, Hector;
Gonzalez‐Robles, Cristina;
Lima, Manuela;
Raposo, Mafalda;
Melo, Ana Rosa Vieira;
de Almeida, Luís Pereira;
Silva, Patrick;
Pinto, Maria M.;
van de Warrenburg, Bart P.;
van Gaalen, Judith

Publication type:

Article

Caffeine and adenosine A(2A) receptor inactivation decrease striatal neuropathology in a lentiviral-based model of Machado-Joseph disease.

Published in:

2013

By:

Gonçalves, Nélio;
Simoes, Ana T;
Cunha, Rodrigo A;
de Almeida, Luís Pereira;
Simões, Ana T

Publication type:

journal article

Characterization of common and rare human papillomaviruses in Portuguese women by the polymerase chain reaction, restriction fragment length polymorphism and sequencing.

Published in:

Journal of Medical Virology, 2010, v. 82, n. 6, p. 1024, doi. 10.1002/jmv.21756

By:

Nobre, Rui Jorge;
Cruz, Eugénia;
Real, Odete;
de Almeida, Luís Pereira;
Martins, Teresa C.

Publication type:

Article

Neuropeptide Y (NPY) intranasal delivery alleviates Machado–Joseph disease.

Published in:

Scientific Reports, 2021, v. 11, n. 1, p. 1, doi. 10.1038/s41598-021-82339-5

By:

Duarte-Neves, Joana;
Cavadas, Cláudia;
Pereira de Almeida, Luís

Publication type:

Article

Autophagy in Spinocerebellar ataxia type 2, a dysregulated pathway, and a target for therapy.

Published in:

Cell Death & Disease, 2021, v. 12, n. 12, p. 1, doi. 10.1038/s41419-021-04404-1

By:

Marcelo, Adriana;
Afonso, Inês T.;
Afonso-Reis, Ricardo;
Brito, David V. C.;
Costa, Rafael G.;
Rosa, Ana;
Alves-Cruzeiro, João;
Ferreira, Benedita;
Henriques, Carina;
Nobre, Rui J.;
Matos, Carlos A.;
de Almeida, Luís Pereira;
Nóbrega, Clévio

Publication type:

Article

Stress granules, RNA-binding proteins and polyglutamine diseases: too much aggregation?

Published in:

Cell Death & Disease, 2021, v. 12, n. 6, p. 1, doi. 10.1038/s41419-021-03873-8

By:

Marcelo, Adriana;
Koppenol, Rebekah;
de Almeida, Luís Pereira;
Matos, Carlos A.;
Nóbrega, Clévio

Publication type:

Article

Differential Temporal Dynamics of Axial and Appendicular Ataxia in SCA3.

Published in:

2022

By:

Maas, Roderick P.P.W.M.;
Teerenstra, Steven;
Lima, Manuela;
Pires, Paula;
Pereira de Almeida, Luís;
van Gaalen, Judith;
Timmann, Dagmar;
Infante, Jon;
Onyike, Chiadi;
Bushara, Khalaf;
Jacobi, Heike;
Reetz, Kathrin;
Santana, Magda M.;
Afonso Ribeiro, Joana;
Hübener‐Schmid, Jeannette;
de Vries, Jeroen J.;
Synofzik, Matthis;
Schöls, Ludger;
Garcia‐Moreno, Hector;
Giunti, Paola

Publication type:

journal article

Characterization of Lifestyle in Spinocerebellar Ataxia Type 3 and Association with Disease Severity.

Published in:

Movement Disorders, 2022, v. 37, n. 2, p. 405, doi. 10.1002/mds.28844

By:

Hengel, Holger;
Martus, Peter;
Faber, Jennifer;
Garcia‐Moreno, Hector;
Solanky, Nita;
Giunti, Paola;
Klockgether, Thomas;
Reetz, Kathrin;
van de Warrenburg, Bart P.;
Pereira de Almeida, Luís;
Santana, Magda M.;
Januário, Cristina;
Silva, Patrick;
Thieme, Andreas;
Infante, Jon;
de Vries, Jeroen;
Lima, Manuela;
Ferreira, Ana F.;
Bushara, Khalaf;
Jacobi, Heike

Publication type:

Article

The autophagy‐enhancing drug carbamazepine improves neuropathology and motor impairment in mouse models of Machado–Joseph disease.

Published in:

Neuropathology & Applied Neurobiology, 2022, v. 48, n. 1, p. 1, doi. 10.1111/nan.12763

By:

Vasconcelos‐Ferreira, Ana;
Carmo‐Silva, Sara;
Codêsso, José Miguel;
Silva, Patrick;
Martinez, Alberto Rolim Muro;
França Jr, Marcondes Cavalcante;
Nóbrega, Clévio;
Pereira de Almeida, Luís

Publication type:

Article

Identification of the calpain‐generated toxic fragment of ataxin‐3 protein provides new avenues for therapy of Machado–Joseph disease| Spinocerebellar ataxia type 3.

Published in:

Neuropathology & Applied Neurobiology, 2022, v. 48, n. 1, p. 1, doi. 10.1111/nan.12748

By:

Simões, Ana Teresa;
Carmona, Vítor;
Duarte‐Neves, Joana;
Cunha‐Santos, Janete;
Pereira de Almeida, Luís

Publication type:

Article

Ibuprofen enhances synaptic function and neural progenitors proliferation markers and improves neuropathology and motor coordination in Machado–Joseph disease models.

Published in:

Human Molecular Genetics, 2019, v. 28, n. 22, p. 3691, doi. 10.1093/hmg/ddz097

By:

Mendonça, Liliana S;
Nóbrega, Clévio;
Tavino, Silvia;
Brinkhaus, Maximilian;
Matos, Carlos;
Tomé, Sandra;
Moreira, Ricardo;
Henriques, Daniel;
Kaspar, Brian K;
Almeida, Luís Pereira de

Publication type:

Article

Cordycepin activates autophagy through AMPK phosphorylation to reduce abnormalities in Machado–Joseph disease models.

Published in:

Human Molecular Genetics, 2019, v. 28, n. 1, p. 51, doi. 10.1093/hmg/ddy328

By:

Marcelo, Adriana;
Brito, Filipa;
Carmo-Silva, Sara;
Matos, Carlos A;
Alves-Cruzeiro, João;
Vasconcelos-Ferreira, Ana;
Koppenol, Rebekah;
Mendonça, Liliana;
Almeida, Luís Pereira de;
Nóbrega, Clévio

Publication type:

Article

Loss of hierarchical imprinting regulation at the Prader–Willi/Angelman syndrome locus in human iPSCs.

Published in:

Human Molecular Genetics, 2018, v. 27, n. 23, p. 3999, doi. 10.1093/hmg/ddy274

By:

Pólvora-Brandão, Duarte;
Joaquim, Mariana;
Godinho, Inês;
Aprile, Domenico;
Álvaro, Ana Rita;
Onofre, Isabel;
Raposo, Ana Cláudia;
Almeida, Luís Pereira de;
Duarte, Sofia T;
Rocha, Simão T da

Publication type:

Article

In Vitro Evaluation of Biphasic Calcium Phosphate Scaffolds Derived from Cuttlefish Bone Coated with Poly(ester urea) for Bone Tissue Regeneration.

Published in:

Polymers (20734360), 2023, v. 15, n. 10, p. 2256, doi. 10.3390/polym15102256

By:

Pereira, Patrícia;
Neto, Ana S.;
Rodrigues, Ana S.;
Barros, Inês;
Miranda, Catarina;
Ramalho-Santos, João;
Pereira de Almeida, Luís;
Ferreira, José M. F.;
Coelho, Jorge F. J.;
Fonseca, Ana C.

Publication type:

Article

Transplantation of cerebellar neural stem cells improves motor coordination and neuropathology in Machado-Joseph disease mice.

Published in:

2015

By:

Mendonça, Liliana S;
Nóbrega, Clévio;
Hirai, Hirokazu;
Kaspar, Brian K;
Pereira de Almeida, Luís

Publication type:

Journal Article

Transplantation of cerebellar neural stem cells improves motor coordination and neuropathology in Machado-Joseph disease mice.

Published in:

Brain: A Journal of Neurology, 2015, v. 138, n. 2, p. 320

By:

Mendonça, Liliana S.;
Nóbrega, Clévio;
Hirai, Hirokazu;
Kaspar, Brian K.;
Pereira de Almeida, Luís

Publication type:

Article

Beclin 1 mitigates motor and neuropathological deficits in genetic mouse models of Machado-Joseph disease.

Published in:

2013

By:

Nascimento-Ferreira, Isabel;
Nóbrega, Clévio;
Vasconcelos-Ferreira, Ana;
Onofre, Isabel;
Albuquerque, David;
Aveleira, Célia;
Hirai, Hirokazu;
Déglon, Nicole;
Pereira de Almeida, Luís

Publication type:

journal article

Beclin 1 mitigates motor and neuropathological deficits in genetic mouse models of Machado–Joseph disease.

Published in:

Brain: A Journal of Neurology, 2013, v. 136, n. 7, p. 2173, doi. 10.1093/brain/awt144

By:

Nascimento-Ferreira, Isabel;
Nóbrega, Clévio;
Vasconcelos-Ferreira, Ana;
Onofre, Isabel;
Albuquerque, David;
Aveleira, Célia;
Hirai, Hirokazu;
Déglon, Nicole;
Pereira de Almeida, Luís

Publication type:

Article

Calpastatin-mediated inhibition of calpains in the mouse brain prevents mutant ataxin 3 proteolysis, nuclear localization and aggregation, relieving Machado-Joseph disease.

Published in:

2012

By:

Simoes AT;
Gonçalves N;
Koeppen A;
Déglon N;
Kügler S;
Duarte CB;
Pereira de Almeida L;
Simões, Ana T;
Gonçalves, Nélio;
Koeppen, Arnulf;
Déglon, Nicole;
Kügler, Sebastian;
Duarte, Carlos Bandeira;
Pereira de Almeida, Luís

Publication type:

journal article

Calpastatin-mediated inhibition of calpains in the mouse brain prevents mutant ataxin 3 proteolysis, nuclear localization and aggregation, relieving Machado–Joseph disease.

Published in:

Brain: A Journal of Neurology, 2012, v. 135, n. 8, p. 2428, doi. 10.1093/brain/aws177

By:

Simões, Ana T.;
Gonçalves, Nélio;
Koeppen, Arnulf;
Déglon, Nicole;
Kügler, Sebastian;
Duarte, Carlos Bandeira;
Pereira de Almeida, Luís

Publication type:

Article

Overexpression of the autophagic beclin-1 protein clears mutant ataxin-3 and alleviates Machado–Joseph disease.

Published in:

Brain: A Journal of Neurology, 2011, v. 134, n. 5, p. 1400, doi. 10.1093/brain/awr047

By:

Nascimento-Ferreira, Isabel;
Santos-Ferreira, Tiago;
Sousa-Ferreira, Lígia;
Auregan, Gwennaëlle;
Onofre, Isabel;
Alves, Sandro;
Dufour, Noëlle;
Colomer Gould, Veronica F.;
Koeppen, Arnulf;
Déglon, Nicole;
Pereira de Almeida, Luís

Publication type:

Article

Trehalose alleviates the phenotype of Machado-Joseph disease mouse models.

Published in:

2020

By:

Santana, Magda M.;
Paixão, Susana;
Cunha-Santos, Janete;
Silva, Teresa Pereira;
Trevino-Garcia, Allyson;
Gaspar, Laetitia S.;
Nóbrega, Clévio;
Nobre, Rui Jorge;
Cavadas, Cláudia;
Greif, Hagar;
Pereira de Almeida, Luís

Publication type:

journal article

Regional distribution of polymorphisms associated to the disease-causing gene of spinocerebellar ataxia type 3.

Published in:

Journal of Neurology, 2025, v. 272, n. 1, p. 1, doi. 10.1007/s00415-024-12829-9

By:

Elter, Tim Lukas;
Sturm, Daniel;
Santana, Magda M.;
Schaprian, Tamara;
Raposo, Mafalda;
Melo, Ana Rosa Vieira;
Lima, Manuela;
Koyak, Berkan;
Oender, Demet;
Grobe-Einsler, Marcus;
Lopes, Sara;
Silva, Patrick;
de Almeida, Luís Pereira;
Giunti, Paola;
Garcia-Moreno, Hector;
Nethisinhe, Suran;
de Vries, Jeroen;
van de Warrenburg, Bart P.;
van Gaalen, Judith;
Synofzik, Matthis

Publication type:

Article

Regional distribution of polymorphisms associated to the disease-causing gene of spinocerebellar ataxia type 3.

Published in:

Journal of Neurology, 2025, v. 272, n. 1, p. 1, doi. 10.1007/s00415-024-12829-9

By:

Elter, Tim Lukas;
Sturm, Daniel;
Santana, Magda M.;
Schaprian, Tamara;
Raposo, Mafalda;
Melo, Ana Rosa Vieira;
Lima, Manuela;
Koyak, Berkan;
Oender, Demet;
Grobe-Einsler, Marcus;
Lopes, Sara;
Silva, Patrick;
de Almeida, Luís Pereira;
Giunti, Paola;
Garcia-Moreno, Hector;
Nethisinhe, Suran;
de Vries, Jeroen;
van de Warrenburg, Bart P.;
van Gaalen, Judith;
Synofzik, Matthis

Publication type:

Article

Correction to: The frequency of non‑motor symptoms in SCA3 and their association with disease severity and lifestyle factors.

Published in:

2024

By:

Hengel, Holger;
Martus, Peter;
Faber, Jennifer;
Giunti, Paola;
Garcia-Moreno, Hector;
Solanky, Nita;
Klockgether, Thomas;
Reetz, Kathrin;
van de Warrenburg, Bart P.;
Santana, Magda M.;
Silva, Patrick;
Cunha, Inês;
de Almeida, Luís Pereira;
Timmann, Dagmar;
Infante, Jon;
de Vries, Jeroen;
Lima, Manuela;
Pires, Paula;
Bushara, Khalaf;
Jacobi, Heike

Publication type:

Correction Notice

The frequency of non-motor symptoms in SCA3 and their association with disease severity and lifestyle factors.

Published in:

Journal of Neurology, 2023, v. 270, n. 2, p. 944, doi. 10.1007/s00415-022-11441-z

By:

Hengel, Holger;
Martus, Peter;
Faber, Jennifer;
Giunit, Paola;
Garcia-Moreno, Hector;
Solanky, Nita;
Klockgether, Thomas;
Reetz, Kathrin;
van de Warrenburg, Bart P.;
Santana, Magda M.;
Silva, Patrick;
Cunha, Inês;
de Almeida, Luís Pereira;
Timmann, Dagmar;
Infante, Jon;
de Vries, Jeroen;
Lima, Manuela;
Pires, Paula;
Bushara, Khalaf;
Jacobi, Heike

Publication type:

Article

Cerebellar morphometric and spectroscopic biomarkers for Machado-Joseph Disease.

Published in:

Acta Neuropathologica Communications, 2022, v. 10, n. 1, p. 1, doi. 10.1186/s40478-022-01329-4

By:

Miranda, Catarina Oliveira;
Nobre, Rui Jorge;
Paiva, Vitor Hugo;
Duarte, João Valente;
Castelhano, João;
Petrella, Lorena Itatí;
Sereno, José;
Santana, Magda;
Afonso, Sónia;
Januário, Cristina;
Castelo-Branco, Miguel;
de Almeida, Luís Pereira

Publication type:

Article

miR-155 modulates microglia-mediated immune response by down-regulating SOCS-1 and promoting cytokine and nitric oxide production.

Published in:

Immunology, 2012, v. 135, n. 1, p. 73, doi. 10.1111/j.1365-2567.2011.03514.x

By:

Cardoso, Ana L.;
Guedes, Joana R.;
Pereira de Almeida, Luís;
Pedroso de Lima, Maria C.

Publication type:

Article

Modeling Lysosomal Storage Disorders in an Innovative Way: Establishment and Characterization of Stem Cell Lines from Human Exfoliated Deciduous Teeth of Mucopolysaccharidosis Type II Patients.

Published in:

International Journal of Molecular Sciences, 2024, v. 25, n. 6, p. 3546, doi. 10.3390/ijms25063546

By:

Carvalho, Sofia;
Santos, Juliana Inês;
Moreira, Luciana;
Duarte, Ana Joana;
Gaspar, Paulo;
Rocha, Hugo;
Encarnação, Marisa;
Ribeiro, Diogo;
Barbosa Almeida, Matilde;
Gonçalves, Mariana;
David, Hugo;
Matos, Liliana;
Amaral, Olga;
Diogo, Luísa;
Ferreira, Sara;
Santos, Constança;
Martins, Esmeralda;
Prata, Maria João;
Pereira de Almeida, Luís;
Alves, Sandra

Publication type:

Article

Phosphoproteome Microarray Analysis of Extracellular Particles as a Tool to Explore Novel Biomarker Candidates for Alzheimer's Disease.

Published in:

International Journal of Molecular Sciences, 2024, v. 25, n. 3, p. 1584, doi. 10.3390/ijms25031584

By:

Soares Martins, Tânia;
Pelech, Steven;
Ferreira, Maria;
Pinho, Beatriz;
Leandro, Kevin;
de Almeida, Luís Pereira;
Breitling, Benedict;
Hansen, Niels;
Esselmann, Hermann;
Wiltfang, Jens;
da Cruz e Silva, Odete A. B.;
Henriques, Ana Gabriela

Publication type:

Article

A Novel Genetic Variant in MBD5 Associated with Severe Epilepsy and Intellectual Disability: Potential Implications on Neural Primary Cilia.

Published in:

International Journal of Molecular Sciences, 2023, v. 24, n. 16, p. 12603, doi. 10.3390/ijms241612603

By:

Martins, Mariana;
Oliveira, Ana Rafaela;
Martins, Solange;
Vieira, José Pedro;
Perdigão, Pedro;
Fernandes, Ana Rita;
de Almeida, Luís Pereira;
Palma, Paulo Jorge;
Sequeira, Diana Bela;
Santos, João Miguel Marques;
Duque, Frederico;
Oliveira, Guiomar;
Cardoso, Ana Luísa;
Peça, João;
Seabra, Catarina Morais

Publication type:

Article

SIRT2 Deficiency Exacerbates Hepatic Steatosis via a Putative Role of the ER Stress Pathway.

Published in:

International Journal of Molecular Sciences, 2022, v. 23, n. 12, p. 6790, doi. 10.3390/ijms23126790

By:

Leal, Helena;
Cardoso, João;
Valério, Patrícia;
Quatorze, Marta;
Carmona, Vítor;
Cunha-Santos, Janete;
Pereira de Almeida, Luís;
Pereira, Cláudia;
Cavadas, Cláudia;
Gomes, Pedro

Publication type:

Article

Extracellular Vesicles Physiological Role and the Particular Case of Disease-Spreading Mechanisms in Polyglutamine Diseases.

Published in:

International Journal of Molecular Sciences, 2021, v. 22, n. 22, p. 12288, doi. 10.3390/ijms222212288

By:

Moreira, Ricardo;
Mendonça, Liliana S.;
Pereira de Almeida, Luís

Publication type:

Article

Living Proof of Activity of Extracellular Vesicles in the Central Nervous System.

Published in:

International Journal of Molecular Sciences, 2021, v. 22, n. 14, p. 7294, doi. 10.3390/ijms22147294

By:

Mahjoum, Shadi;
Rufino-Ramos, David;
Pereira de Almeida, Luís;
Broekman, Marike L. D.;
Breakefield, Xandra O.;
van Solinge, Thomas S.

Publication type:

Article

Ataxin-3 phosphorylation decreases neuronal defects in spinocerebellar ataxia type 3 models.

Published in:

Journal of Cell Biology, 2016, v. 212, n. 4, p. 465, doi. 10.1083/jcb.201506025

By:

Matos, Carlos A.;
Nóbrega, Clévio;
Louros, Susana R.;
Almeida, Bruno;
Ferreiro, Elisabete;
Valero, Jorge;
de Almeida, Luís Pereira;
Macedo-Ribeiro, Sandra;
Carvalho, Ana Luísa

Publication type:

Article

Caloric restriction blocks neuropathology and motor deficits in Machado-Joseph disease mouse models through SIRT1 pathway.

Published in:

Nature Communications, 2016, v. 7, n. 5, p. 11445, doi. 10.1038/ncomms11445

By:

Cunha-Santos, Janete;
Duarte-Neves, Joana;
Carmona, Vitor;
Guarente, Leonard;
Pereira de Almeida, Luís;
Cavadas, Cláudia

Publication type:

Article

IGF-1 Intranasal Administration Rescues Huntington's Disease Phenotypes in YAC128 Mice.

Published in:

Molecular Neurobiology, 2014, v. 49, n. 3, p. 1126, doi. 10.1007/s12035-013-8585-5

By:

Lopes, Carla;
Ribeiro, Márcio;
Duarte, Ana;
Humbert, Sandrine;
Saudou, Frederic;
Pereira de Almeida, Luís;
Hayden, Michael;
Rego, A.

Publication type:

Article

The blood-brain barrier is disrupted in Machado-Joseph disease/spinocerebellar ataxia type 3: evidence from transgenic mice and human post-mortem samples.

Published in:

Acta Neuropathologica Communications, 2020, v. 8, n. 1, p. N.PAG, doi. 10.1186/s40478-020-00955-0

By:

Duarte Lobo, Diana;
Nobre, Rui Jorge;
Oliveira Miranda, Catarina;
Pereira, Dina;
Castelhano, João;
Sereno, José;
Koeppen, Arnulf;
Castelo-Branco, Miguel;
Pereira de Almeida, Luís

Publication type:

Article

Neuropeptide Y mitigates neuropathology and motor deficits in mouse models of Machado-Joseph disease.

Published in:

Human Molecular Genetics, 2015, v. 24, n. 19, p. 5451, doi. 10.1093/hmg/ddv271

By:

Duarte-Neves, Joana;
Gonçalves, Nélio;
Cunha-Santos, Janete;
Simões, Ana Teresa;
den Dunnen, Wilfred F. A.;
Hirokazu Hirai;
Kügler, Sebastian;
Cavadas, Cláudia;
de Almeida, Luís Pereira

Publication type:

Article

Calpain inhibition reduces ataxin-3 cleavage alleviating neuropathology and motor impairments in mouse models of Machado–Joseph disease.

Published in:

Human Molecular Genetics, 2014, v. 23, n. 18, p. 4932, doi. 10.1093/hmg/ddu209

By:

Simões, Ana Teresa;
Gonçalves, Nélio;
Nobre, Rui Jorge;
Duarte, Carlos Bandeira;
Pereira de Almeida, Luís

Publication type:

Article

MicroRNA-21 silencing enhances the cytotoxic effect of the antiangiogenic drug sunitinib in glioblastoma.

Published in:

Human Molecular Genetics, 2013, v. 22, n. 5, p. 904, doi. 10.1093/hmg/dds496

By:

Costa, Pedro M.;
Cardoso, Ana L.;
Nóbrega, Clévio;
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Article

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Human Molecular Genetics, 2010, v. 19, n. 12, p. 2380, doi. 10.1093/hmg/ddq111

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Alves, Sandro;
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Dufour, Noëlle;
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Auregan, Gwennaëlle;
Nóbrega, Clévio;
Brouillet, Emmanuel;
Hantraye, Philippe;
Pedroso de Lima, Maria C.;
Déglon, Nicole;
de Almeida, Luís Pereira

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Striatal and nigral pathology in a lentiviral rat model of Machado-Joseph disease.

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Human Molecular Genetics, 2008, v. 17, n. 14, p. 2071, doi. 10.1093/hmg/ddn106

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Alves, Sandro;
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Nascimento-Ferreira, Isabel;
Hassig, Raymonde;
Dufour, Noelle;
Koeppen, Arnulf;
Carvalho, Ana Luísa;
Simões, Sérgio;
de Lima, Maria C. Pedroso;
Brouillet, Emmanuel;
Gould, Veronica Colomer;
Déglon, Nicole;
de Almeida, Luís Pereira

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Mannose and Lactobionic Acid in Nasal Vaccination: Enhancing Antigen Delivery via C-Type Lectin Receptors.

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Pharmaceutics, 2024, v. 16, n. 10, p. 1308, doi. 10.3390/pharmaceutics16101308

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Colaço, Mariana;
Cruz, Maria T.;
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Article