Works by Perdomo, Germán

Results: 25

Pharmacological activation of insulin‐degrading enzyme improves insulin secretion and glucose tolerance in diet‐induced obese mice.

Published in:

Diabetes, Obesity & Metabolism, 2023, v. 25, n. 11, p. 3268, doi. 10.1111/dom.15225

By:

Sanz‐González, Alba;
Cózar‐Castellano, Irene;
Broca, Christophe;
Sabatier, Julia;
Acosta, Gerardo A.;
Royo, Miriam;
Hernándo‐Muñoz, Carla;
Torroba, Tomás;
Perdomo, Germán;
Merino, Beatriz

Publication type:

Article

Modulation of Insulin Sensitivity by Insulin-Degrading Enzyme.

Published in:

Biomedicines, 2021, v. 9, n. 1, p. 86, doi. 10.3390/biomedicines9010086

By:

González-Casimiro, Carlos M.;
Merino, Beatriz;
Casanueva-Álvarez, Elena;
Postigo-Casado, Tamara;
Cámara-Torres, Patricia;
Fernández-Díaz, Cristina M.;
Leissring, Malcolm A.;
Cózar-Castellano, Irene;
Perdomo, Germán

Publication type:

Article

Effects of Fasting and Feeding on Transcriptional and Posttranscriptional Regulation of Insulin-Degrading Enzyme in Mice.

Published in:

Cells (2073-4409), 2021, v. 10, n. 9, p. 2446, doi. 10.3390/cells10092446

By:

González-Casimiro, Carlos M.;
Cámara-Torres, Patricia;
Merino, Beatriz;
Diez-Hermano, Sergio;
Postigo-Casado, Tamara;
Leissring, Malcolm A.;
Cózar-Castellano, Irene;
Perdomo, Germán

Publication type:

Article

Placental Compartmentalization of Lipid Metabolism: Implications for Singleton and Twin Pregnancies.

Published in:

Reproductive Sciences, 2021, v. 28, n. 4, p. 1150, doi. 10.1007/s43032-020-00385-2

By:

Abascal-Saiz, Alejandra;
Fuente-Luelmo, Eva;
Haro, María;
de la Calle, María;
Ramos-Álvarez, María P.;
Perdomo, Germán;
Bartha, José L.

Publication type:

Article

Cloning, sequencing, and expression of H.a.YNR1 and H.a.YNI1, encoding nitrate and nitrite reductases in the yeast Hansenula anomala.

Published in:

Yeast, 2000, v. 16, n. 12, p. 1099, doi. 10.1002/1097-0061(20000915)16:12<1099::AID-YEA596>3.0.CO;2-S

By:

García-Lugo, Pablo;
González, Celedonio;
Perdomo, Germán;
Brito, Nélida;
Ávila, Julio;
de la Rosa, José M.;
Siverio, José M.

Publication type:

Article

One-step, PCR-mediated, gene disruption in the yeast Hansenula polymorpha.

Published in:

Yeast, 1999, v. 15, n. 13, p. 1323, doi. 10.1002/(SICI)1097-0061(19990930)15:13<1323::AID-YEA459>3.0.CO;2-1

By:

González, Celedonio;
Perdomo, Germán;
Tejera, Paula;
Brito, Nélida;
Siverio, José M.

Publication type:

Article

Prepregnancy body mass index influences lipid oxidation rate during pregnancy.

Published in:

2017

By:

Bugatto, Fernando;
Quintero‐Prado, Rocío;
Vilar‐Sánchez, José M.;
Perdomo, Germán;
Torrejón, Rafael;
Bartha, José L.

Publication type:

journal article

Excess Hydrocortisone Hampers Placental Nutrient Uptake Disrupting Cellular Metabolism.

Published in:

BioMed Research International, 2018, p. 1, doi. 10.1155/2018/5106174

By:

Mateos, Rosa María;
Jiménez, Gema;
Álvarez-Gil, Carmen;
Visiedo, Francisco;
Rivera-Rodríguez, Fátima;
Santos-Rosendo, Celeste;
Rodriguez-Pareja, Antonia;
Perdomo, Germán;
Lechuga-Sancho, Alfonso M.

Publication type:

Article

Targeting Insulin-Degrading Enzyme in Insulin Clearance.

Published in:

International Journal of Molecular Sciences, 2021, v. 22, n. 5, p. 2235, doi. 10.3390/ijms22052235

By:

Leissring, Malcolm A.;
González-Casimiro, Carlos M.;
Merino, Beatriz;
Suire, Caitlin N.;
Perdomo, Germán;
Gastaldelli, Amalia

Publication type:

Article

Protective effects of epoxypukalide on pancreatic β-cells and glucose metabolism in STZ-induced diabetic mice.

Published in:

Islets, 2015, v. 7, n. 2, p. N.PAG, doi. 10.1080/19382014.2015.1078053

By:

López-Acosta, Jose F;
Villa-Pérez, Pablo;
Fernández-Díaz, Cristina M;
Román, Daniel de Luis;
Díaz-Marrero, Ana R;
Cueto, Mercedes;
Perdomo, Germán;
Cózar-Castellano, Irene

Publication type:

Article

Primary Cilia in Pancreatic β- and α-Cells: Time to Revisit the Role of Insulin-Degrading Enzyme.

Published in:

Frontiers in Endocrinology, 2022, v. 13, p. 1, doi. 10.3389/fendo.2022.922825

By:

Pablos, Marta;
Casanueva-Álvarez, Elena;
González-Casimiro, Carlos M.;
Merino, Beatriz;
Perdomo, Germán;
Cózar-Castellano, Irene

Publication type:

Article

Manipulation of Transmembrane Transport by Synthetic K<sup>+</sup> Ionophore Depsipeptides and Its Implications in Glucose‐Stimulated Insulin Secretion in β‐Cells.

Published in:

Chemistry - A European Journal, 2019, v. 25, n. 39, p. 9287, doi. 10.1002/chem.201901372

By:

García‐Calvo, José;
Torroba, Tomás;
Brañas‐Fresnillo, Virginia;
Perdomo, Germán;
Cózar‐Castellano, Irene;
Li, Yu‐Hao;
Legrand, Yves‐Marie;
Barboiu, Mihail

Publication type:

Article

Hyperglucagonemia and glucagon hypersecretion in early type 2 diabetes result from multifaceted dysregulation of pancreatic mouse α-cells.

Published in:

Pflügers Archiv: European Journal of Physiology, 2025, v. 477, n. 2, p. 207, doi. 10.1007/s00424-024-03045-5

By:

Ruiz-Pino, Antonia;
Goncalves-Ramírez, Arianna;
Jiménez-Palomares, Margarita;
Merino, Beatriz;
Castellano-Muñoz, Manuel;
Vettorazzi, Jean F.;
Rafacho, Alex;
Marroquí, Laura;
Nadal, Ángel;
Alonso-Magdalena, Paloma;
Perdomo, Germán;
Cózar-Castellano, Irene;
Quesada, Ivan

Publication type:

Article

Correction to: Insulin-degrading enzyme ablation in mouse pancreatic alpha cells triggers cell proliferation, hyperplasia and glucagon secretion dysregulation.

Published in:

2024

By:

Merino, Beatriz;
Casanueva-Álvarez, Elena;
Quesada, Iván;
González-Casimiro, Carlos M.;
Fernández-Díaz, Cristina M.;
Postigo-Casado, Tamara;
Leissring, Malcolm A.;
Kaestner, Klaus H.;
Perdomo, Germán;
Cózar-Castellano, Irene

Publication type:

Correction Notice

Insulin-degrading enzyme ablation in mouse pancreatic alpha cells triggers cell proliferation, hyperplasia and glucagon secretion dysregulation.

Published in:

Diabetologia, 2022, v. 65, n. 8, p. 1375, doi. 10.1007/s00125-022-05729-y

By:

Merino, Beatriz;
Casanueva-Álvarez, Elena;
Quesada, Iván;
González-Casimiro, Carlos M.;
Fernández-Díaz, Cristina M.;
Postigo-Casado, Tamara;
Leissring, Malcolm A.;
Kaestner, Klaus H.;
Perdomo, Germán;
Cózar-Castellano, Irene

Publication type:

Article

The Relationship between Angiogenic Factors and Energy Metabolism in Preeclampsia.

Published in:

Nutrients, 2022, v. 14, n. 10, p. 2172, doi. 10.3390/nu14102172

By:

Abascal-Saiz, Alejandra;
Duque-Alcorta, Marta;
Fioravantti, Victoria;
Antolín, Eugenia;
Fuente-Luelmo, Eva;
Haro, María;
Ramos-Álvarez, María P.;
Perdomo, Germán;
Bartha, José L.

Publication type:

Article

Targeted delivery of HGF to the skeletal muscle improves glucose homeostasis in diet-induced obese mice.

Published in:

Journal of Physiology & Biochemistry, 2015, v. 71, n. 4, p. 795, doi. 10.1007/s13105-015-0444-6

By:

Sanchez-Encinales, Viviana;
Cozar-Castellano, Irene;
Garcia-Ocaña, Adolfo;
Perdomo, Germán

Publication type:

Article

Epoxypukalide Induces Proliferation and Protects against Cytokine-Mediated Apoptosis in Primary Cultures of Pancreatic β-Cells.

Published in:

PLoS ONE, 2013, v. 8, n. 1, p. 1, doi. 10.1371/journal.pone.0052862

By:

López-Acosta, José Francisco;
Moreno-Amador, José Luis;
Jiménez-Palomares, Margarita;
Díaz-Marrero, Ana R.;
Cueto, Mercedes;
Perdomo, Germán;
Cózar-Castellano, Irene

Publication type:

Article

Inhibition of Fatty Acid Metabolism Reduces Human Myeloma Cells Proliferation.

Published in:

PLoS ONE, 2012, v. 7, n. 9, p. 1, doi. 10.1371/journal.pone.0046484

By:

Tirado-Vélez, José Manuel;
Joumady, Insaf;
Sáez-Benito, Ana;
Cózar-Castellano, Irene;
Perdomo, Germán;
Bhattacharya, Samir

Publication type:

Article

Glucose and Fatty Acid Metabolism in Placental Explants From Pregnancies Complicated With Gestational Diabetes Mellitus.

Published in:

Reproductive Sciences, 2015, v. 22, n. 7, p. 798, doi. 10.1177/1933719114561558

By:

Visiedo, Francisco;
Bugatto, Fernando;
Quintero-Prado, Rocío;
Cózar-Castellano, Irene;
Bartha, Jose L.;
Perdomo, Germán

Publication type:

Article

Chloro-Furanocembranolides from Leptogorgia sp. Improve Pancreatic Beta-Cell Proliferation.

Published in:

Marine Drugs, 2018, v. 16, n. 2, p. 49, doi. 10.3390/md16020049

By:

Gallardo, Amalia B.;
Díaz-Marrero, Ana R.;
de la Rosa, José M.;
D’Croz, Luis;
Perdomo, Germán;
Cózar-Castellano, Irene;
Darias, José;
Cueto, Mercedes

Publication type:

Article

Leptolide Improves Insulin Resistance in Diet-Induced Obese Mice.

Published in:

Marine Drugs, 2017, v. 15, n. 9, p. 289, doi. 10.3390/md15090289

By:

Villa-Pérez, Pablo;
Lobatón, Carmen D.;
Moreno, Alfredo;
Cózar-Castellano, Irene;
Cueto, Mercedes;
Díaz-Marrero, Ana R.;
Perdomo, Germán

Publication type:

Article

β2-Chimaerin, a GTPase-Activating Protein for Rac1, Is a Novel Regulator of Hepatic Insulin Signaling and Glucose Metabolism.

Published in:

Molecules, 2024, v. 29, n. 22, p. 5301, doi. 10.3390/molecules29225301

By:

Carmona-Carmona, Cristian Andrés;
Zini, Pablo;
Velasco-Sampedro, Eladio A.;
Cózar-Castellano, Irene;
Perdomo, Germán;
Caloca, María J.

Publication type:

Article

Low-density lipoprotein cholesterol suppresses apoptosis in human multiple myeloma cells.

Published in:

Annals of Hematology, 2012, v. 91, n. 1, p. 83, doi. 10.1007/s00277-011-1246-8

By:

Tirado-Vélez, Jose;
Benítez-Rondán, Alicia;
Cózar-Castellano, Irene;
Medina, Francisco;
Perdomo, Germán

Publication type:

Article

Tissue specific expression of human fatty acid oxidation enzyme genes in late pregnancy.

Published in:

Lipids in Health & Disease, 2016, v. 15, p. 1, doi. 10.1186/s12944-016-0373-6

By:

Bartha, Jose L.;
Bugatto, Fernando;
Fernández-Deudero, Álvaro;
Fernández-Macías, Rosa;
Perdomo, Germán

Publication type:

Article