Works by Peppicelli, Silvia

Results: 38

Inflammatory cytokines induce vascular endothelial growth factor-C expression in melanoma-associated macrophages and stimulate melanoma lymph node metastasis.

Published in:

Oncology Letters, 2014, v. 8, n. 3, p. 1133, doi. 10.3892/ol.2014.2297

By:

PEPPICELLI, SILVIA;
BIANCHINI, FRANCESCA;
CALORINI, LIDO

Publication type:

Article

Gold Nanoparticles Functionalized with RGD‐Semipeptides: A Simple yet Highly Effective Targeting System for α<sub>V</sub>β<sub>3</sub> Integrins.

Published in:

Chemistry - A European Journal, 2018, v. 24, n. 46, p. 12093, doi. 10.1002/chem.201801823

By:

Maggi, Vito;
Bianchini, Francesca;
Portioli, Elisabetta;
Peppicelli, Silvia;
Lulli, Matteo;
Bani, Daniele;
Sole, Roberta Del;
Zanardi, Franca;
Sartori, Andrea;
Fiammengo, Roberto

Publication type:

Article

Triazole RGD antagonist reverts TGFβ1-induced endothelial-to-mesenchymal transition in endothelial precursor cells.

Published in:

Molecular & Cellular Biochemistry, 2017, v. 424, n. 1/2, p. 99, doi. 10.1007/s11010-016-2847-2

By:

Bianchini, Francesca;
Peppicelli, Silvia;
Fabbrizzi, Pierangelo;
Biagioni, Alessio;
Mazzanti, Benedetta;
Menchi, Gloria;
Calorini, Lido;
Pupi, Alberto;
Trabocchi, Andrea

Publication type:

Article

Acidity and hypoxia of tumor microenvironment, a positive interplay in extracellular vesicle release by tumor cells.

Published in:

2025

By:

Peppicelli, Silvia;
Calorini, Lido;
Bianchini, Francesca;
Papucci, Laura;
Magnelli, Lucia;
Andreucci, Elena

Publication type:

Literature Review

Chronic Resveratrol Treatment Inhibits MRC5 Fibroblast SASP-Related Protumoral Effects on Melanoma Cells.

Published in:

2017

By:

Menicacci, Beatrice;
Laurenzana, Anna;
Chillà, Anastasia;
Margheri, Francesca;
Peppicelli, Silvia;
Tanganelli, Elisabetta;
Fibbi, Gabriella;
Giovannelli, Lisa;
Del Rosso, Mario;
Mocali, Alessandra

Publication type:

journal article

The Carbonic Anhydrase IX inhibitor SLC-0111 as emerging agent against the mesenchymal stem cell-derived pro-survival effects on melanoma cells.

Published in:

Journal of Enzyme Inhibition & Medicinal Chemistry, 2020, v. 35, n. 1, p. 1185, doi. 10.1080/14756366.2020.1764549

By:

Peppicelli, Silvia;
Andreucci, Elena;
Ruzzolini, Jessica;
Bianchini, Francesca;
Nediani, Chiara;
Supuran, Claudiu T.;
Calorini, Lido

Publication type:

Article

A potentiated cooperation of carbonic anhydrase IX and histone deacetylase inhibitors against cancer.

Published in:

Journal of Enzyme Inhibition & Medicinal Chemistry, 2020, v. 35, n. 1, p. 391, doi. 10.1080/14756366.2019.1706090

By:

Ruzzolini, Jessica;
Laurenzana, Anna;
Andreucci, Elena;
Peppicelli, Silvia;
Bianchini, Francesca;
Carta, Fabrizio;
Supuran, Claudiu T.;
Romanelli, Maria Novella;
Nediani, Chiara;
Calorini, Lido

Publication type:

Article

The carbonic anhydrase IX inhibitor SLC-0111 sensitises cancer cells to conventional chemotherapy.

Published in:

Journal of Enzyme Inhibition & Medicinal Chemistry, 2019, v. 34, n. 1, p. 117, doi. 10.1080/14756366.2018.1532419

By:

Andreucci, Elena;
Ruzzolini, Jessica;
Peppicelli, Silvia;
Bianchini, Francesca;
Laurenzana, Anna;
Carta, Fabrizio;
Supuran, Claudiu T.;
Calorini, Lido

Publication type:

Article

uPA/uPAR system activation drives a glycolytic phenotype in melanoma cells.

Published in:

International Journal of Cancer, 2017, v. 141, n. 6, p. 1190, doi. 10.1002/ijc.30817

By:

Laurenzana, Anna;
Chillà, Anastasia;
Luciani, Cristina;
Peppicelli, Silvia;
Biagioni, Alessio;
Bianchini, Francesca;
Tenedini, Elena;
Torre, Eugenio;
Mocali, Alessandra;
Calorini, Lido;
Margheri, Francesca;
Fibbi, Gabriella;
Del Rosso, Mario

Publication type:

Article

miR-214-Enriched Extracellular Vesicles Released by Acid-Adapted Melanoma Cells Promote Inflammatory Macrophage-Dependent Tumor Trans-Endothelial Migration.

Published in:

Cancers, 2022, v. 14, n. 20, p. 5090, doi. 10.3390/cancers14205090

By:

Andreucci, Elena;
Ruzzolini, Jessica;
Bianchini, Francesca;
Versienti, Giampaolo;
Biagioni, Alessio;
Lulli, Matteo;
Guasti, Daniele;
Nardini, Patrizia;
Serratì, Simona;
Margheri, Francesca;
Laurenzana, Anna;
Nediani, Chiara;
Peppicelli, Silvia;
Calorini, Lido

Publication type:

Article

Glutamine Availability Controls BCR/Abl Protein Expression and Functional Phenotype of Chronic Myeloid Leukemia Cells Endowed with Stem/Progenitor Cell Potential.

Published in:

Cancers, 2021, v. 13, n. 17, p. 4372, doi. 10.3390/cancers13174372

By:

Poteti, Martina;
Menegazzi, Giulio;
Peppicelli, Silvia;
Tusa, Ignazia;
Cheloni, Giulia;
Silvano, Angela;
Mancini, Caterina;
Biagioni, Alessio;
Tubita, Alessandro;
Mazure, Nathalie M.;
Lulli, Matteo;
Rovida, Elisabetta;
Dello Sbarba, Persio

Publication type:

Article

Claisened Hexafluoro Inhibits Metastatic Spreading of Amoeboid Melanoma Cells.

Published in:

Cancers, 2021, v. 13, n. 14, p. 3551, doi. 10.3390/cancers13143551

By:

Leo, Angela;
Pranzini, Erica;
Pietrovito, Laura;
Pardella, Elisa;
Parri, Matteo;
Cirri, Paolo;
Bruno, Gennaro;
Calvani, Maura;
Peppicelli, Silvia;
Torre, Eugenio;
Sasaki, Maiko;
Yang, Lily;
Zhu, Lei;
Chiarugi, Paola;
Raugei, Giovanni;
Arbiser, Jack L.;
Taddei, Maria Letizia

Publication type:

Article

Cancer Glycolytic Dependence as a New Target of Olive Leaf Extract.

Published in:

Cancers, 2020, v. 12, n. 2, p. 317, doi. 10.3390/cancers12020317

By:

Ruzzolini, Jessica;
Peppicelli, Silvia;
Bianchini, Francesca;
Andreucci, Elena;
Urciuoli, Silvia;
Romani, Annalisa;
Tortora, Katia;
Caderni, Giovanna;
Nediani, Chiara;
Calorini, Lido

Publication type:

Article

Potential Role of HLA Class I Antigens in the Glycolytic Metabolism and Motility of Melanoma Cells.

Published in:

Cancers, 2019, v. 11, n. 9, p. 1249, doi. 10.3390/cancers11091249

By:

Peppicelli, Silvia;
Ruzzolini, Jessica;
Andreucci, Elena;
Bianchini, Francesca;
Kontos, Filippos;
Yamada, Teppei;
Ferrone, Soldano;
Calorini, Lido

Publication type:

Article

Metformin is also effective on lactic acidosis-exposed melanoma cells switched to oxidative phosphorylation.

Published in:

Cell Cycle, 2016, v. 15, n. 14, p. 1908, doi. 10.1080/15384101.2016.1191706

By:

Peppicelli, Silvia;
Toti, Alessandra;
Giannoni, Elisa;
Bianchini, Francesca;
Margheri, Francesca;
Del Rosso, Mario;
Calorini, Lido

Publication type:

Article

Extracellular acidity strengthens mesenchymal stem cells to promote melanoma progression.

Published in:

Cell Cycle, 2015, v. 14, n. 19, p. 3088, doi. 10.1080/15384101.2015.1078032

By:

Peppicelli, Silvia;
Bianchini, Francesca;
Toti, Alessandra;
Laurenzana, Anna;
Fibbi, Gabriella;
Calorini, Lido

Publication type:

Article

The metabolically-modulated stem cell niche: a dynamic scenario regulating cancer cell phenotype and resistance to therapy.

Published in:

Cell Cycle, 2014, v. 13, n. 20, p. 3169, doi. 10.4161/15384101.2014.964107

By:

Rovida, Elisabetta;
Peppicelli, Silvia;
Bono, Silvia;
Bianchini, Francesca;
Tusa, Ignazia;
Cheloni, Giulia;
Marzi, Ilaria;
Cipolleschi, Maria Grazia;
Calorini, Lido;
Sbarba, Persio Dello

Publication type:

Article

Contribution of acidic melanoma cells undergoing epithelial-to-mesenchymal transition to aggressiveness of non-acidic melanoma cells.

Published in:

Clinical & Experimental Metastasis, 2014, v. 31, n. 4, p. 423, doi. 10.1007/s10585-014-9637-6

By:

Peppicelli, Silvia;
Bianchini, Francesca;
Torre, Eugenio;
Calorini, Lido

Publication type:

Article

Acidic pH via NF-κB favours VEGF-C expression in human melanoma cells.

Published in:

Clinical & Experimental Metastasis, 2013, v. 30, n. 8, p. 957, doi. 10.1007/s10585-013-9595-4

By:

Peppicelli, Silvia;
Bianchini, Francesca;
Contena, Claudia;
Tombaccini, Donatella;
Calorini, Lido

Publication type:

Article

CD63 Tetraspanin Is a Negative Driver of Epithelial-to-Mesenchymal Transition in Human Melanoma Cells.

Published in:

Journal of Investigative Dermatology, 2014, v. 134, n. 12, p. 2947, doi. 10.1038/jid.2014.258

By:

Lupia, Antonella;
Peppicelli, Silvia;
Witort, Ewa;
Bianchini, Francesca;
Carloni, Vinicio;
Pimpinelli, Nicola;
Urso, Carmelo;
Borgognoni, Lorenzo;
Capaccioli, Sergio;
Calorini, Lido;
Lulli, Matteo

Publication type:

Article

BCR::ABL1 expression in chronic myeloid leukemia cells in low oxygen is regulated by glutamine via CD36-mediated fatty acid uptake.

Published in:

Cancer Cell International, 2025, v. 25, n. 1, p. 1, doi. 10.1186/s12935-025-03805-y

By:

Mancini, Caterina;
Menegazzi, Giulio;
Peppicelli, Silvia;
Versienti, Giampaolo;
Guasti, Daniele;
Pieraccini, Giuseppe;
Rovida, Elisabetta;
Lulli, Matteo;
Papucci, Laura;
Dello Sbarba, Persio;
Biagioni, Alessio

Publication type:

Article

SOX2 as a novel contributor of oxidative metabolism in melanoma cells.

Published in:

Cell Communication & Signaling, 2018, v. 16, n. 1, p. N.PAG, doi. 10.1186/s12964-018-0297-z

By:

Andreucci, Elena;
Peppicelli, Silvia;
Ruzzolini, Jessica;
Bianchini, Francesca;
Biagioni, Alessio;
Calorini, Lido;
Pietrobono, Silvia;
Stecca, Barbara

Publication type:

Article

Lactate Maintains BCR/Abl Expression and Signaling in Chronic Myeloid Leukemia Cells Under Nutrient Restriction.

Published in:

Oncology Research, 2021, v. 29, n. 1, p. 33, doi. 10.3727/096504022X16442289212164

By:

Silvano, Angela;
Menegazzi, Giulio;
Peppicelli, Silvia;
Mancini, Caterina;
Biagioni, Alessio;
Tubita, Alessandro;
Tusa, Ignazia;
Ruzzolini, Jessica;
Lulli, Matteo;
Rovida, Elisabetta;
Sbarba, Persio Dello

Publication type:

Article

uPAR Controls Vasculogenic Mimicry Ability Expressed by Drug-Resistant Melanoma Cells.

Published in:

Oncology Research, 2020, v. 28, n. 9, p. 873, doi. 10.3727/096504021X16273798026651

By:

Andreucci, Elena;
Laurenzana, Anna;
Peppicelli, Silvia;
Biagioni, Alessio;
Margheri, Francesca;
Ruzzolini, Jessica;
Bianchini, Francesca;
Fibbi, Gabriella;
Del Rosso, Mario;
Nediani, Chiara;
Serrat, Simona;
Fucci, Livia;
Guida, Michele;
Calorini, Lido

Publication type:

Article

Nintedanib-αVβ6 Integrin Ligand Conjugates Reduce TGF β -Induced EMT in Human Non-Small Cell Lung Cancer.

Published in:

International Journal of Molecular Sciences, 2023, v. 24, n. 2, p. 1475, doi. 10.3390/ijms24021475

By:

Andreucci, Elena;
Bugatti, Kelly;
Peppicelli, Silvia;
Ruzzolini, Jessica;
Lulli, Matteo;
Calorini, Lido;
Battistini, Lucia;
Zanardi, Franca;
Sartori, Andrea;
Bianchini, Francesca

Publication type:

Article

Extracellular Acidosis Differentially Regulates Estrogen Receptor β-Dependent EMT Reprogramming in Female and Male Melanoma Cells.

Published in:

International Journal of Molecular Sciences, 2022, v. 23, n. 23, p. 15374, doi. 10.3390/ijms232315374

By:

Peppicelli, Silvia;
Ruzzolini, Jessica;
Lulli, Matteo;
Biagioni, Alessio;
Bianchini, Francesca;
Caldarella, Adele;
Nediani, Chiara;
Andreucci, Elena;
Calorini, Lido

Publication type:

Article

Oleuropein, the Main Polyphenol of Olea europaea Leaf Extract, Has an Anti-Cancer Effect on Human BRAF Melanoma Cells and Potentiates the Cytotoxicity of Current Chemotherapies.

Published in:

Nutrients, 2018, v. 10, n. 12, p. 1950, doi. 10.3390/nu10121950

By:

Ruzzolini, Jessica;
Peppicelli, Silvia;
Andreucci, Elena;
Bianchini, Francesca;
Scardigli, Arianna;
Romani, Annalisa;
la Marca, Giancarlo;
Nediani, Chiara;
Calorini, Lido

Publication type:

Article

Physicochemical aspects of the tumour microenvironment as drivers of vasculogenic mimicry.

Published in:

Cancer & Metastasis Reviews, 2022, v. 41, n. 4, p. 935, doi. 10.1007/s10555-022-10067-x

By:

Andreucci, Elena;
Peppicelli, Silvia;
Ruzzolini, Jessica;
Bianchini, Francesca;
Calorini, Lido

Publication type:

Article

Extracellular acidity, a 'reappreciated' trait of tumor environment driving malignancy: perspectives in diagnosis and therapy.

Published in:

Cancer & Metastasis Reviews, 2014, v. 33, n. 2/3, p. 823, doi. 10.1007/s10555-014-9506-4

By:

Peppicelli, Silvia;
Bianchini, Francesca;
Calorini, Lido

Publication type:

Article

The acidic tumor microenvironment drives a stem-like phenotype in melanoma cells.

Published in:

Journal of Molecular Medicine, 2020, v. 98, n. 10, p. 1431, doi. 10.1007/s00109-020-01959-y

By:

Andreucci, Elena;
Peppicelli, Silvia;
Ruzzolini, Jessica;
Bianchini, Francesca;
Biagioni, Alessio;
Papucci, Laura;
Magnelli, Lucia;
Mazzanti, Benedetta;
Stecca, Barbara;
Calorini, Lido

Publication type:

Article

Carbonic anhydrase IX inhibition affects viability of cancer cells adapted to extracellular acidosis.

Published in:

Journal of Molecular Medicine, 2017, v. 95, n. 12, p. 1341, doi. 10.1007/s00109-017-1590-9

By:

Andreucci, Elena;
Peppicelli, Silvia;
Carta, Fabrizio;
Brisotto, Giulia;
Biscontin, Eva;
Ruzzolini, Jessica;
Bianchini, Francesca;
Biagioni, Alessio;
Supuran, Claudiu;
Calorini, Lido

Publication type:

Article

Inhibition of uPAR-TGFβ crosstalk blocks MSC-dependent EMT in melanoma cells.

Published in:

Journal of Molecular Medicine, 2015, v. 93, n. 7, p. 783, doi. 10.1007/s00109-015-1266-2

By:

Laurenzana, Anna;
Biagioni, Alessio;
Bianchini, Francesca;
Peppicelli, Silvia;
Chillà, Anastasia;
Margheri, Francesca;
Luciani, Cristina;
Pimpinelli, Nicola;
Del Rosso, Mario;
Calorini, Lido;
Fibbi, Gabriella

Publication type:

Article

An Oleocanthal-Enriched EVO Oil Extract Induces the ROS Production in Gastric Cancer Cells and Potentiates the Effect of Chemotherapy.

Published in:

Antioxidants, 2022, v. 11, n. 9, p. 1762, doi. 10.3390/antiox11091762

By:

Peri, Sara;
Ruzzolini, Jessica;
Urciuoli, Silvia;
Versienti, Giampaolo;
Biagioni, Alessio;
Andreucci, Elena;
Peppicelli, Silvia;
Bianchini, Francesca;
Bottari, Andrea;
Calorini, Lido;
Nediani, Chiara;
Magnelli, Lucia;
Papucci, Laura

Publication type:

Article

Oleuropein-Rich Leaf Extract as a Broad Inhibitor of Tumour and Macrophage iNOS in an Apc Mutant Rat Model.

Published in:

Antioxidants, 2021, v. 10, n. 10, p. 1577, doi. 10.3390/antiox10101577

By:

Ruzzolini, Jessica;
Chioccioli, Sofia;
Monaco, Noemi;
Peppicelli, Silvia;
Andreucci, Elena;
Urciuoli, Silvia;
Romani, Annalisa;
Luceri, Cristina;
Tortora, Katia;
Calorini, Lido;
Caderni, Giovanna;
Nediani, Chiara;
Bianchini, Francesca

Publication type:

Article

CRISPR/Cas9 uPAR Gene Knockout Results in Tumor Growth Inhibition, EGFR Downregulation and Induction of Stemness Markers in Melanoma and Colon Carcinoma Cell Lines.

Published in:

Frontiers in Oncology, 2021, v. 11, p. N.PAG, doi. 10.3389/fonc.2021.663225

By:

Biagioni, Alessio;
Chillà, Anastasia;
Del Rosso, Mario;
Fibbi, Gabriella;
Scavone, Francesca;
Andreucci, Elena;
Peppicelli, Silvia;
Bianchini, Francesca;
Calorini, Lido;
Li Santi, Anna;
Ragno, Pia;
Margheri, Francesca;
Laurenzana, Anna

Publication type:

Article

Glycolysis-derived acidic microenvironment as a driver of endothelial dysfunction in systemic sclerosis.

Published in:

Rheumatology, 2021, v. 60, n. 10, p. 4508, doi. 10.1093/rheumatology/keab022

By:

Andreucci, Elena;
Margheri, Francesca;
Peppicelli, Silvia;
Bianchini, Francesca;
Ruzzolini, Jessica;
Laurenzana, Anna;
Fibbi, Gabriella;
Bruni, Cosimo;
Bellando-Randone, Silvia;
Guiducci, Serena;
Romano, Eloisa;
Manetti, Mirko;
Matucci-Cerinic, Marco;
Calorini, Lido

Publication type:

Article

uPAR-expressing melanoma exosomes promote angiogenesis by VE-Cadherin, EGFR and uPAR overexpression and rise of ERK1,2 signaling in endothelial cells.

Published in:

Cellular & Molecular Life Sciences, 2021, v. 78, n. 6, p. 3057, doi. 10.1007/s00018-020-03707-4

By:

Biagioni, Alessio;
Laurenzana, Anna;
Menicacci, Beatrice;
Peppicelli, Silvia;
Andreucci, Elena;
Bianchini, Francesca;
Guasti, Daniele;
Paoli, Paolo;
Serratì, Simona;
Mocali, Alessandra;
Calorini, Lido;
Del Rosso, Mario;
Fibbi, Gabriella;
Chillà, Anastasia;
Margheri, Francesca

Publication type:

Article

The acidic microenvironment as a possible niche of dormant tumor cells.

Published in:

Cellular & Molecular Life Sciences, 2017, v. 74, n. 15, p. 2761, doi. 10.1007/s00018-017-2496-y

By:

Peppicelli, Silvia;
Andreucci, Elena;
Ruzzolini, Jessica;
Laurenzana, Anna;
Margheri, Francesca;
Fibbi, Gabriella;
Del Rosso, Mario;
Bianchini, Francesca;
Calorini, Lido

Publication type:

Article