Works matching AU Peng, Ren-Wang

Results: 31

Molecular engineering of exocytic vesicle traffic enhances the productivity of Chinese hamster ovary cells.

Published in:

Biotechnology & Bioengineering, 2009, v. 102, n. 4, p. 1170, doi. 10.1002/bit.22141

By:

Peng, Ren-Wang;
Fussenegger, Martin

Publication type:

Article

LDHB silencing enhances the effects of radiotherapy by impairing nucleotide metabolism and promoting persistent DNA damage.

Published in:

Scientific Reports, 2025, v. 15, n. 1, p. 1, doi. 10.1038/s41598-025-95633-3

By:

Deng, Haibin;
Malsiu, Fatlind;
Ge, Huixiang;
Losmanova, Tereza;
Medová, Michaela;
Zamboni, Nicola;
Wang, Wenxiang;
Peng, Ren-Wang;
Tang, Jinming;
Dorn, Patrick;
Marti, Thomas Michael

Publication type:

Article

Advancing cancer therapy: new frontiers in targeting DNA damage response.

Published in:

Frontiers in Pharmacology, 2024, p. 1, doi. 10.3389/fphar.2024.1474337

By:

Qian, Jiekun;
Liao, Guoliang;
Chen, Maohui;
Peng, Ren-Wang;
Yan, Xin;
Du, Jianting;
Huang, Renjie;
Pan, Maojie;
Lin, Yuxing;
Gong, Xian;
Xu, Guobing;
Zheng, Bin;
Chen, Chun;
Yang, Zhang

Publication type:

Article

Ubiquinol-mediated suppression of mitochondria-associated ferroptosis is a targetable function of lactate dehydrogenase B in cancer.

Published in:

Nature Communications, 2025, v. 16, n. 1, p. 1, doi. 10.1038/s41467-025-57906-3

By:

Deng, Haibin;
Zhao, Liang;
Ge, Huixiang;
Gao, Yanyun;
Fu, Yan;
Lin, Yantang;
Masoodi, Mojgan;
Losmanova, Tereza;
Medová, Michaela;
Ott, Julien;
Su, Min;
Wang, Wenxiang;
Peng, Ren-Wang;
Dorn, Patrick;
Marti, Thomas Michael

Publication type:

Article

Biomarker-guided targeted and immunotherapies in malignant pleural mesothelioma.

Published in:

Therapeutic Advances in Medical Oncology, 2020, p. 1, doi. 10.1177/1758835920971421

By:

Yang, Haitang;
Xu, Duo;
Schmid, Ralph A.;
Peng, Ren-Wang

Publication type:

Article

Increased sensitivity to apoptosis upon endoplasmic reticulum stress-induced activation of the unfolded protein response in chemotherapy-resistant malignant pleural mesothelioma.

Published in:

2018

By:

Xu, Duo;
Liang, Shun-Qing;
Yang, Haitang;
Lüthi, Ursina;
Riether, Carsten;
Berezowska, Sabina;
Marti, Thomas M.;
Hall, Sean R. R.;
Bruggmann, Rémy;
Kocher, Gregor J.;
Schmid, Ralph A.;
Peng, Ren-Wang

Publication type:

journal article

Schedule-Dependent Treatment Increases Chemotherapy Efficacy in Malignant Pleural Mesothelioma.

Published in:

International Journal of Molecular Sciences, 2022, v. 23, n. 19, p. 11949, doi. 10.3390/ijms231911949

By:

Karatkevich, Darya;
Deng, Haibin;
Gao, Yanyun;
Flint, Emilio;
Peng, Ren-Wang;
Schmid, Ralph Alexander;
Dorn, Patrick;
Marti, Thomas Michael

Publication type:

Article

Therapeutic Landscape of Malignant Pleural Mesothelioma: Collateral Vulnerabilities and Evolutionary Dependencies in the Spotlight.

Published in:

Frontiers in Oncology, 2020, v. 10, p. N.PAG, doi. 10.3389/fonc.2020.579464

By:

Xu, Duo;
Yang, Haitang;
Schmid, Ralph A.;
Peng, Ren-Wang

Publication type:

Article

New Horizons in KRAS -Mutant Lung Cancer: Dawn After Darkness.

Published in:

Frontiers in Oncology, 2019, p. 1, doi. 10.3389/fonc.2019.00953

By:

Yang, Haitang;
Liang, Shun-Qing;
Schmid, Ralph A.;
Peng, Ren-Wang

Publication type:

Article

Beyond DNA Repair: DNA-PKcs in Tumor Metastasis, Metabolism and Immunity.

Published in:

Cancers, 2020, v. 12, n. 11, p. 3389, doi. 10.3390/cancers12113389

By:

Yang, Haitang;
Yao, Feng;
Marti, Thomas M.;
Schmid, Ralph A.;
Peng, Ren-Wang

Publication type:

Article

Pharmacotranscriptomic Analysis Reveals Novel Drugs and Gene Networks Regulating Ferroptosis in Cancer.

Published in:

Cancers, 2020, v. 12, n. 11, p. 3273, doi. 10.3390/cancers12113273

By:

Yang, Haitang;
Zhao, Liang;
Gao, Yanyun;
Yao, Feng;
Marti, Thomas M.;
Schmid, Ralph A.;
Peng, Ren-Wang

Publication type:

Article

Systematic Analysis of Aberrant Biochemical Networks and Potential Drug Vulnerabilities Induced by Tumor Suppressor Loss in Malignant Pleural Mesothelioma.

Published in:

Cancers, 2020, v. 12, n. 8, p. 2310, doi. 10.3390/cancers12082310

By:

Yang, Haitang;
Xu, Duo;
Yang, Zhang;
Yao, Feng;
Zhao, Heng;
Schmid, Ralph A.;
Peng, Ren-Wang

Publication type:

Article

Endoplasmic Reticulum Stress Signaling as a Therapeutic Target in Malignant Pleural Mesothelioma.

Published in:

Cancers, 2019, v. 11, n. 10, p. 1502, doi. 10.3390/cancers11101502

By:

Xu, Duo;
Yang, Haitang;
Yang, Zhang;
Berezowska, Sabina;
Gao, Yanyun;
Liang, Shun-Qing;
Marti, Thomas M.;
Hall, Sean R. R.;
Dorn, Patrick;
Kocher, Gregor J.;
Schmid, Ralph A.;
Peng, Ren-Wang

Publication type:

Article

Synergistic effects of FGFR1 and PLK1 inhibitors target a metabolic liability in KRAS‐mutant cancer.

Published in:

EMBO Molecular Medicine, 2021, v. 13, n. 9, p. 1, doi. 10.15252/emmm.202013193

By:

Yang, Zhang;
Liang, Shun‐Qing;
Saliakoura, Maria;
Yang, Haitang;
Vassella, Eric;
Konstantinidou, Georgia;
Tschan, Mario;
Hegedüs, Balazs;
Zhao, Liang;
Gao, Yanyun;
Xu, Duo;
Deng, Haibin;
Marti, Thomas M;
Kocher, Gregor J;
Wang, Wenxiang;
Schmid, Ralph A;
Peng, Ren‐Wang

Publication type:

Article

Mutations of the SM protein Sly1 resulting in bypass of GTPase requirement in vesicular transport are confined to a short helical region

Published in:

FEBS Letters, 2007, v. 581, n. 29, p. 5698, doi. 10.1016/j.febslet.2007.11.033

By:

Li, Yujie;
Schmitt, Hans Dieter;
Gallwitz, Dieter;
Peng, Ren-Wang

Publication type:

Article

An optimized protocol for the generation and monitoring of conditional orthotopic lung cancer in the KP mouse model using an adeno-associated virus vector compatible with biosafety level 1.

Published in:

Cancer Immunology, Immunotherapy, 2023, v. 72, n. 12, p. 4457, doi. 10.1007/s00262-023-03542-z

By:

Deng, Haibin;
Ge, Huixiang;
Dubey, Christelle;
Losmanova, Tereza;
Medová, Michaela;
Konstantinidou, Georgia;
Mutlu, Seyran Mathilde;
Birrer, Fabienne Esther;
Brodie, Tess Melinda;
Stroka, Deborah;
Wang, Wenxiang;
Peng, Ren-Wang;
Dorn, Patrick;
Marti, Thomas Michael

Publication type:

Article

Metabolic synthetic lethality by targeting NOP56 and mTOR in KRAS-mutant lung cancer.

Published in:

Journal of Experimental & Clinical Cancer Research (17569966), 2022, v. 41, n. 1, p. 1, doi. 10.1186/s13046-022-02240-5

By:

Yang, Zhang;
Liang, Shun-Qing;
Zhao, Liang;
Yang, Haitang;
Marti, Thomas M.;
Hegedüs, Balazs;
Gao, Yanyun;
Zheng, Bin;
Chen, Chun;
Wang, Wenxiang;
Dorn, Patrick;
Kocher, Gregor J.;
Schmid, Ralph A.;
Peng, Ren-Wang

Publication type:

Article

Chemotherapy-induced CDA expression renders resistant non-small cell lung cancer cells sensitive to 5′-deoxy-5-fluorocytidine (5′-DFCR).

Published in:

Journal of Experimental & Clinical Cancer Research (17569966), 2021, v. 40, n. 1, p. 1, doi. 10.1186/s13046-021-01938-2

By:

Gao, Yanyun;
Zens, Philipp;
Su, Min;
Gemperli, Camila Anna;
Yang, Haitang;
Deng, Haibin;
Yang, Zhang;
Xu, Duo;
Hall, Sean R. R.;
Berezowska, Sabina;
Dorn, Patrick;
Peng, Ren-Wang;
Schmid, Ralph Alexander;
Wang, Wenxiang;
Marti, Thomas Michael

Publication type:

Article

HSP90/AXL/eIF4E-regulated unfolded protein response as an acquired vulnerability in drug-resistant KRAS-mutant lung cancer.

Published in:

Oncogenesis, 2019, v. 8, n. 9, p. N.PAG, doi. 10.1038/s41389-019-0158-7

By:

Yang, Haitang;
Liang, Shun-Qing;
Xu, Duo;
Yang, Zhang;
Marti, Thomas M.;
Gao, Yanyun;
Kocher, Gregor J.;
Zhao, Heng;
Schmid, Ralph A.;
Peng, Ren-Wang

Publication type:

Article

CRISPRing KRAS : A Winding Road with a Bright Future in Basic and Translational Cancer Research.

Published in:

Cancers, 2024, v. 16, n. 2, p. 460, doi. 10.3390/cancers16020460

By:

Gong, Xian;
Du, Jianting;
Peng, Ren-Wang;
Chen, Chun;
Yang, Zhang

Publication type:

Article

Dissecting the Immunological Profiles in NSD3 -Amplified LUSC through Integrative Multi-Scale Analyses.

Published in:

Cancers, 2022, v. 14, n. 20, p. 4997, doi. 10.3390/cancers14204997

By:

Xu, Duo;
Liu, Shengchen;
Wu, Xi;
Marti, Thomas M.;
Dorn, Patrick;
Schmid, Ralph A.;
Peng, Ren-Wang;
Shu, Yongqian

Publication type:

Article

Organoids as a Model for Precision Medicine in Malignant Pleural Mesothelioma: Where Are We Today?

Published in:

Cancers, 2022, v. 14, n. 15, p. 3758, doi. 10.3390/cancers14153758

By:

Gao, Yanyun;
Kruithof-de Julio, Marianna;
Peng, Ren-Wang;
Dorn, Patrick

Publication type:

Article

A Breakthrough Brought about by Targeting KRAS G12C : Nonconformity Is Punished.

Published in:

Cancers, 2022, v. 14, n. 2, p. 390, doi. 10.3390/cancers14020390

By:

Ning, Wenjuan;
Yang, Zhang;
Kocher, Gregor J.;
Dorn, Patrick;
Peng, Ren-Wang

Publication type:

Article

NF2 and Canonical Hippo-YAP Pathway Define Distinct Tumor Subsets Characterized by Different Immune Deficiency and Treatment Implications in Human Pleural Mesothelioma.

Published in:

Cancers, 2021, v. 13, n. 7, p. 1561, doi. 10.3390/cancers13071561

By:

Yang, Haitang;
Hall, Sean R. R.;
Sun, Beibei;
Zhao, Liang;
Gao, Yanyun;
Schmid, Ralph A.;
Tan, Swee T.;
Peng, Ren-Wang;
Yao, Feng;
Stella, Giulia M;
Bortolotto, Chandra

Publication type:

Article

Dendritic cell/cytokine‐induced killer cell‐based immunotherapy in lung cancer: What we know and future landscape.

Published in:

Journal of Cellular Physiology, 2020, v. 235, n. 1, p. 74, doi. 10.1002/jcp.28977

By:

Mohsenzadegan, Monireh;
Peng, Ren‐Wang;
Roudi, Raheleh

Publication type:

Article

Transitional CXCL14<sup>+</sup> cancer‐associated fibroblasts enhance tumour metastasis and confer resistance to EGFR‐TKIs, revealing therapeutic vulnerability to filgotinib in lung adenocarcinoma.

Published in:

Clinical & Translational Medicine, 2025, v. 15, n. 4, p. 1, doi. 10.1002/ctm2.70281

By:

Xu, Weijiao;
Yang, Haitang;
Xu, Ke;
Zhu, Anshun;
Hall, Sean R. R.;
Jia, Yunxuan;
Zhao, Baicheng;
Zhang, Enshuo;
Liu, Gang;
Xu, Jianlin;
Marti, Thomas M.;
Peng, Ren‐Wang;
Dorn, Patrick;
Niu, Yongliang;
Pan, Xufeng;
Zhang, Yajuan;
Yao, Feng

Publication type:

Article

Cisplatin-resistant A549 non-small cell lung cancer cells can be identified by increased mitochondrial mass and are sensitive to pemetrexed treatment.

Published in:

Cancer Cell International, 2019, v. 19, n. 1, p. N.PAG, doi. 10.1186/s12935-019-1037-1

By:

Gao, Yanyun;
Dorn, Patrick;
Liu, Shengchen;
Deng, Haibin;
Hall, Sean R. R.;
Peng, Ren-Wang;
Schmid, Ralph A.;
Marti, Thomas M.

Publication type:

Article

Prolonged pemetrexed pretreatment augments persistence of cisplatin-induced DNA damage and eliminates resistant lung cancer stem-like cells associated with EMT.

Published in:

2016

By:

Tièche, Colin Charles;
Ren-Wang Peng;
Dorn, Patrick;
Froment, Laurène;
Schmid, Ralph Alexander;
Marti, Thomas Michael;
Peng, Ren-Wang

Publication type:

journal article

MEK1 drives oncogenic signaling and interacts with PARP1 for genomic and metabolic homeostasis in malignant pleural mesothelioma.

Published in:

Cell Death Discovery, 2023, v. 9, n. 1, p. 1, doi. 10.1038/s41420-023-01307-2

By:

Yang, Haitang;
Gao, Yanyun;
Xu, Duo;
Xu, Ke;
Liang, Shun-Qing;
Yang, Zhang;
Scherz, Amina;
Hall, Sean R. R.;
Forster, Stefan;
Berezowska, Sabina;
Yao, Feng;
Ochsenbein, Adrian F.;
Marti, Thomas M.;
Kocher, Gregor J.;
Schmid, Ralph A.;
Dorn, Patrick;
Peng, Ren-Wang

Publication type:

Article

Malignant pleural mesothelioma co-opts BCL-XL and autophagy to escape apoptosis.

Published in:

Cell Death & Disease, 2021, v. 12, n. 4, p. 1, doi. 10.1038/s41419-021-03668-x

By:

Xu, Duo;
Liang, Shun-Qing;
Yang, Zhang;
Yang, Haitang;
Bruggmann, Rémy;
Oberhaensli, Simone;
Berezowska, Sabina;
Marti, Thomas M.;
Hall, Sean R. R.;
Dorn, Patrick;
Kocher, Gregor J.;
Schmid, Ralph A.;
Peng, Ren-Wang

Publication type:

Article

Targeting lactate dehydrogenase B-dependent mitochondrial metabolism affects tumor initiating cells and inhibits tumorigenesis of non-small cell lung cancer by inducing mtDNA damage.

Published in:

Cellular & Molecular Life Sciences, 2022, v. 79, n. 8, p. 1, doi. 10.1007/s00018-022-04453-5

By:

Deng, Haibin;
Gao, Yanyun;
Trappetti, Verdiana;
Hertig, Damian;
Karatkevich, Darya;
Losmanova, Tereza;
Urzi, Christian;
Ge, Huixiang;
Geest, Gerrit Adriaan;
Bruggmann, Remy;
Djonov, Valentin;
Nuoffer, Jean-Marc;
Vermathen, Peter;
Zamboni, Nicola;
Riether, Carsten;
Ochsenbein, Adrian;
Peng, Ren-Wang;
Kocher, Gregor Jan;
Schmid, Ralph Alexander;
Dorn, Patrick

Publication type:

Article