Works by Pelletier, Joelle N

Results: 33

Selectively weakened binding of methotrexate by human dihydrofolate reductase allows rapid ex vivo selection of mammalian cells.

Published in:

Journal of Molecular Recognition, 2011, v. 24, n. 2, p. 188, doi. 10.1002/jmr.1037

By:

Volpato, Jordan P.;
Mayotte, Nadine;
Fossati, Elena;
Guerrero, Vanessa;
Sauvageau, Guy;
Pelletier, Joelle N.

Publication type:

Article

Sequence-activity relationships guide directed evolution.

Published in:

Nature Biotechnology, 2007, v. 25, n. 3, p. 297, doi. 10.1038/nbt0307-297

By:

Pelletier, Joelle N;
Lortie, Robert

Publication type:

Article

A RACHITT for our toolbox.

Published in:

Nature Biotechnology, 2001, v. 19, n. 4, p. 314, doi. 10.1038/86681

By:

Pelletier, Joelle N.

Publication type:

Article

An in vivo library-versus-library selection of optimized protein?protein interactions.

Published in:

Nature Biotechnology, 1999, v. 17, n. 7, p. 683, doi. 10.1038/10897

By:

Pelletier, Joelle N.;
Arndt, Katja M.;
Plückthun, Andreas;
Michnick, Stephen W.

Publication type:

Article

The bioorganic chemistry of transglutaminase — from mechanism to inhibition and engineering.

Published in:

Canadian Journal of Chemistry, 2008, v. 86, n. 4, p. 271, doi. 10.1139/V08-024

By:

Keillor, Jeffrey W.;
Chica, Roberto A.;
Chabot, Nicolas;
Vinci, Valerio;
Pardin, Christophe;
Fortin, Emanuelle;
Gillet, Steve M.F.G.;
Nakano, Yukiko;
Kaartinen, Mari T.;
Pelletier, Joelle N.;
Lubell, William D.

Publication type:

Article

Methods for enzyme library creation: Which one will you choose?: A guide for novices and experts to introduce genetic diversity.

Published in:

BioEssays, 2021, v. 43, n. 8, p. 1, doi. 10.1002/bies.202100052

By:

Alejaldre, Lorea;
Pelletier, Joelle N.;
Quaglia, Daniela

Publication type:

Article

Infection Rate and Risk Factors of SARS-CoV-2 Infection in Retail Workers at the Onset of the COVID-19 Pandemic, Quebec, Canada.

Published in:

Infectious Disease Reports, 2024, v. 16, n. 6, p. 1240, doi. 10.3390/idr16060098

By:

Santerre, Kim;
Thériault, Mathieu;
Brousseau, Nicholas;
Langlois, Marc-André;
Arnold, Corey;
Pelletier, Joelle N.;
Gilbert, Caroline;
Masson, Jean-François;
Baz, Mariana;
Boudreau, Denis;
Trottier, Sylvie

Publication type:

Article

Crystallization of the bifunctional methylenetetrahydrofolate dehydrogenase/methenyltetrahydrofolate cyclohydrolase domain of the human trifunctional enzyme.

Published in:

Proteins, 1996, v. 26, n. 4, p. 479, doi. 10.1002/(SICI)1097-0134(199612)26:4<479::AID-PROT9>3.0.CO;2-6

By:

Allaire, Marc;
Li, Yunge;
Mejia, Narciso R.;
Pelletier, Joelle N.;
MacKenzie, Robert E.;
Cygler, Miroslaw

Publication type:

Article

Discovery of Highly Trimethoprim-Resistant DfrB Dihydrofolate Reductases in Diverse Environmental Settings Suggests an Evolutionary Advantage Unrelated to Antibiotic Resistance.

Published in:

Antibiotics (2079-6382), 2022, v. 11, n. 12, p. 1768, doi. 10.3390/antibiotics11121768

By:

Cellier-Goetghebeur, Stella;
Lafontaine, Kiana;
Lemay-St-Denis, Claudèle;
Tsamo, Princesse;
Bonneau-Burke, Alexis;
Copp, Janine N.;
Pelletier, Joelle N.

Publication type:

Article

The Bacterial Genomic Context of Highly Trimethoprim-Resistant DfrB Dihydrofolate Reductases Highlights an Emerging Threat to Public Health.

Published in:

Antibiotics (2079-6382), 2021, v. 10, n. 4, p. 433, doi. 10.3390/antibiotics10040433

By:

Lemay-St-Denis, Claudèle;
Diwan, Sarah-Slim;
Pelletier, Joelle N.

Publication type:

Article

Enzyme engineering: A synthetic biology approach for more effective library generation and automated high-throughput screening.

Published in:

PLoS ONE, 2017, v. 12, n. 2, p. 1, doi. 10.1371/journal.pone.0171741

By:

Quaglia, Daniela;
Ebert, Maximilian C. C. J. C.;
Mugford, Paul F.;
Pelletier, Joelle N.

Publication type:

Article

Engineered, highly reactive substrates of microbial transglutaminase enable protein labeling within various secondary structure elements.

Published in:

Protein Science: A Publication of the Protein Society, 2017, v. 26, n. 11, p. 2268, doi. 10.1002/pro.3286

By:

Rachel, Natalie M.;
Quaglia, Daniela;
Lévesque, Éric;
Charette, André B.;
Pelletier, Joelle N.

Publication type:

Article

Asymmetric mutations in the tetrameric R67 dihydrofolate reductase reveal high tolerance to active-site substitutions.

Published in:

Protein Science: A Publication of the Protein Society, 2015, v. 24, n. 4, p. 495, doi. 10.1002/pro.2602

By:

Ebert, Maximilian C. C. J. C.;
Morley, Krista L.;
Volpato, Jordan P.;
Schmitzer, Andreea R.;
Pelletier, Joelle N.

Publication type:

Article

High tolerance to simultaneous active-site mutations in TEM-1 β-lactamase: Distinct mutational paths provide more generalized β-lactam recognition.

Published in:

Protein Science: A Publication of the Protein Society, 2009, v. 18, n. 1, p. 147, doi. 10.1002/pro.25

By:

De Wals, Pierre-Yves;
Doucet, Nicolas;
Pelletier, Joelle N.

Publication type:

Article

Tissue transglutaminase acylation: Proposed role of conserved active site Tyr and Trp residues revealed by molecular modeling of peptide substrate binding.

Published in:

Protein Science: A Publication of the Protein Society, 2004, v. 13, n. 4, p. 979, doi. 10.1110/ps.03433304

By:

Chica, Roberto A.;
Gagnon, Paul;
Keillor, Jeffrey W.;
Pelletier, Joelle N.

Publication type:

Article

The Structural Dynamics of Engineered β-Lactamases Vary Broadly on Three Timescales yet Sustain Native Function.

Published in:

Scientific Reports, 2019, v. 9, n. 1, p. N.PAG, doi. 10.1038/s41598-019-42866-8

By:

Gobeil, Sophie M. C.;
Ebert, Maximillian C. C. J. C.;
Park, Jaeok;
Gagné, Donald;
Doucet, Nicolas;
Berghuis, Albert M.;
Pleiss, Jürgen;
Pelletier, Joelle N.

Publication type:

Article

Longitudinal determination of seroprevalence and immune response to SARS-CoV-2 in a population of food and retail workers through decentralized testing and transformation of ELISA datasets.

Published in:

PLoS ONE, 2024, v. 19, n. 12, p. 1, doi. 10.1371/journal.pone.0314499

By:

Djaïleb, Abdelhadi;
Parker, Megan-Faye;
Lavallée, Étienne;
Stuible, Matthew;
Durocher, Yves;
Thériault, Mathieu;
Santerre, Kim;
Gilbert, Caroline;
Boudreau, Denis;
Baz, Mariana;
Masson, Jean-Francois;
Langlois, Marc-André;
Trottier, Sylvie;
Quaglia, Daniela;
Pelletier, Joelle N.

Publication type:

Article

Trimethoprim resistance in surface and wastewater is mediated by contrasting variants of the dfrB gene.

Published in:

ISME Journal: Multidisciplinary Journal of Microbial Ecology, 2023, v. 17, n. 9, p. 1455, doi. 10.1038/s41396-023-01460-7

By:

Kneis, David;
Lemay-St-Denis, Claudèle;
Cellier-Goetghebeur, Stella;
Elena, Alan X.;
Berendonk, Thomas U.;
Pelletier, Joelle N.;
Heß, Stefanie

Publication type:

Article

Simulated annealing exploration of an active-site tyrosine in TEM-1β-lactamase suggests the existence of alternate conformations.

Published in:

Proteins, 2007, v. 69, n. 2, p. 340, doi. 10.1002/prot.21485

By:

Doucet, Nicolas;
Pelletier, Joelle N.

Publication type:

Article

Biotechnological Applications of Transglutaminases.

Published in:

Biomolecules (2218-273X), 2013, v. 3, n. 4, p. 870, doi. 10.3390/biom3040870

By:

Rachel, Natalie M.;
Pelletier, Joelle N.

Publication type:

Article

Impact of SARS-CoV-2 vaccination and of seasonal variations on the innate immune inflammatory response.

Published in:

Frontiers in Immunology, 2025, p. 1, doi. 10.3389/fimmu.2024.1513717

By:

Jarras, Hend;
Blais, Isalie;
Goyer, Benjamin;
Bazié, Wilfried W.;
Rabezanahary, Henintsoa;
Thériault, Mathieu;
Santerre, Kim;
Langlois, Marc-André;
Masson, Jean-François;
Pelletier, Joelle N.;
Brousseau, Nicholas;
Boudreau, Denis;
Trottier, Sylvie;
Baz, Mariana;
Gilbert, Caroline

Publication type:

Article

Holistic engineering of Cal-A lipase chain-length selectivity identifies triglyceride binding hot-spot.

Published in:

PLoS ONE, 2019, v. 14, n. 1, p. 1, doi. 10.1371/journal.pone.0210100

By:

Quaglia, Daniela;
Alejaldre, Lorea;
Ouadhi, Sara;
Rousseau, Olivier;
Pelletier, Joelle N.

Publication type:

Article

Chimeric β-Lactamases: Global Conservation of Parental Function and Fast Time-Scale Dynamics with Increased Slow Motions.

Published in:

PLoS ONE, 2012, v. 7, n. 12, p. 1, doi. 10.1371/journal.pone.0052283

By:

Clouthier, Christopher M.;
Morin, Sé bastien;
Gobeil, Sophie M. C.;
Doucet, Nicolas;
Blanchet, Jonathan;
Nguyen, Elisabeth;
Gagné, Stéphane M.;
Pelletier, Joelle N.

Publication type:

Article

Cross-reactivity of antibodies from non-hospitalized COVID-19 positive individuals against the native, B.1.351, B.1.617.2, and P.1 SARS-CoV-2 spike proteins.

Published in:

Scientific Reports, 2021, v. 11, n. 1, p. 1, doi. 10.1038/s41598-021-00844-z

By:

Hojjat Jodaylami, Maryam;
Djaïleb, Abdelhadi;
Ricard, Pierre;
Lavallée, Étienne;
Cellier-Goetghebeur, Stella;
Parker, Megan-Faye;
Coutu, Julien;
Stuible, Matthew;
Gervais, Christian;
Durocher, Yves;
Desautels, Florence;
Cayer, Marie-Pierre;
de Grandmont, Marie Joëlle;
Rochette, Samuel;
Brouard, Danny;
Trottier, Sylvie;
Boudreau, Denis;
Pelletier, Joelle N.;
Masson, Jean-Francois

Publication type:

Article

Author Correction: Cross-reactivity of antibodies from non-hospitalized COVID-19 positive individuals against the native, B.1.351, B.1.617.2, and P.1 SARS-CoV-2 spike proteins.

Published in:

2021

By:

Hojjat Jodaylami, Maryam;
Djaïleb, Abdelhadi;
Ricard, Pierre;
Lavallée, Étienne;
Cellier-Goetghebeur, Stella;
Parker, Megan-Faye;
Coutu, Julien;
Stuible, Matthew;
Gervais, Christian;
Durocher, Yves;
Desautels, Florence;
Cayer, Marie-Pierre;
de Grandmont, Marie Joëlle;
Rochette, Samuel;
Brouard, Danny;
Trottier, Sylvie;
Boudreau, Denis;
Pelletier, Joelle N.;
Masson, Jean-Francois

Publication type:

Correction Notice

Cross-reactivity of antibodies from non-hospitalized COVID-19 positive individuals against the native, B.1.351, B.1.617.2, and P.1 SARS-CoV-2 spike proteins.

Published in:

Scientific Reports, 2021, v. 11, n. 1, p. 1, doi. 10.1038/s41598-021-00844-z

By:

Hojjat Jodaylami, Maryam;
Djaïleb, Abdelhadi;
Ricard, Pierre;
Lavallée, Étienne;
Cellier-Goethebeur, Stella;
Parker, Megan-Faye;
Coutu, Julien;
Stuible, Matthew;
Gervais, Christian;
Durocher, Yves;
Desautels, Florence;
Cayer, Marie-Pierre;
de Grandmont, Marie Joëlle;
Rochette, Samuel;
Brouard, Danny;
Trottier, Sylvie;
Boudreau, Denis;
Pelletier, Joelle N.;
Masson, Jean-Francois

Publication type:

Article

Indigo Formation and Rapid NADPH Consumption Provide Robust Prediction of Raspberry Ketone Synthesis by Engineered Cytochrome P450 BM3.

Published in:

ChemCatChem, 2020, v. 12, n. 3, p. 837, doi. 10.1002/cctc.201901974

By:

Rousseau, Olivier;
Ebert, Maximilian C. C. J. C.;
Quaglia, Daniela;
Fendri, Ali;
Parisien, Adem H.;
Besna, Jonathan N.;
Iyathurai, Saathanan;
Pelletier, Joelle N.

Publication type:

Article

Integrating dynamics into enzyme engineering.

Published in:

PEDS: Protein Engineering, Design & Selection, 2022, v. 35, p. 1, doi. 10.1093/protein/gzac015

By:

Lemay-St-Denis, Claudèle;
Doucet, Nicolas;
Pelletier, Joelle N

Publication type:

Article

Combinatorial exploration of the catalytic site of a drug-resistant dihydrofolate reductase: creating alternative functional configurations.

Published in:

PEDS: Protein Engineering, Design & Selection, 2004, v. 17, n. 11, p. 809, doi. 10.1093/protein/gzh090

By:

Andreea R. Schmitzer;
Franois Lpine;
Joelle N. Pelletier

Publication type:

Article

Investigation of Classical Organic and Ionic Liquid Cosolvents for Early-Stage Screening in Fragment-Based Inhibitor Design with Unrelated Bacterial and Human Dihydrofolate Reductases.

Published in:

Assay & Drug Development Technologies, 2017, v. 15, n. 4, p. 141, doi. 10.1089/adt.2016.768

By:

Toulouse, Jacynthe L.;
Abraham, Sarah M. J.;
Kadnikova, Natalia;
Bastien, Dominic;
Gauchot, Vincent;
Schmitzer, Andreea R.;
Pelletier, Joelle N.

Publication type:

Article

Investigation of Classical Organic and Ionic Liquid Cosolvents for Early-Stage Screening in Fragment-Based Inhibitor Design with Unrelated Bacterial and Human Dihydrofolate Reductases.

Published in:

Assay & Drug Development Technologies, 2017, v. 15, n. 4, p. 141, doi. 10.1089/adt.2016.768

By:

Toulouse, Jacynthe L.;
Abraham, Sarah M. J.;
Kadnikova, Natalia;
Bastien, Dominic;
Gauchot, Vincent;
Schmitzer, Andreea R.;
Pelletier, Joelle N.

Publication type:

Article

Assessment of the longitudinal humoral response in non-hospitalized SARS-CoV-2-positive individuals at decentralized sites: Outcomes and concordance.

Published in:

Frontiers in Immunology, 2023, v. 14, p. 1, doi. 10.3389/fimmu.2022.1052424

By:

Djaïleb, Abdelhadi;
Lavallée, Étienne;
Parker, Megan-Faye;
Cayer, Marie-Pierre;
Desautels, Florence;
de Grandmont, Marie Joëlle;
Stuible, Matthew;
Gervais, Christian;
Durocher, Yves;
Trottier, Sylvie;
Boudreau, Denis;
Masson, Jean-Francois;
Brouard, Danny;
Pelletier, Joelle N.

Publication type:

Article

15N, 13C and 1H backbone resonance assignments of an artificially engineered TEM-1/PSE-4 class A β-lactamase chimera and its deconvoluted mutant.

Published in:

Biomolecular NMR Assignments, 2016, v. 10, n. 1, p. 93, doi. 10.1007/s12104-015-9645-8

By:

Gobeil, Sophie M. C.;
Gagné, Donald;
Doucet, Nicolas;
Pelletier, Joelle N.

Publication type:

Article