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Identification of novel myelodysplastic syndromes prognostic subgroups by integration of inflammation, cell-type composition, and immune signatures in the bone marrow.
- Published in:
- eLife, 2024, p. 1, doi. 10.7554/eLife.97096
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- Publication type:
- Article
The Effects of Severe Hypoxia on Glycolytic Flux and Enzyme Activity in a Model of Solid Tumors.
- Published in:
- Journal of Cellular Biochemistry, 2016, v. 117, n. 8, p. 1890, doi. 10.1002/jcb.25488
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- Publication type:
- Article
Phospholipase C beta1 (PI‐PLCbeta1)/Cyclin D3/protein kinase C (PKC) alpha signaling modulation during iron‐induced oxidative stress in myelodysplastic syndromes (MDS).
- Published in:
- FASEB Journal, 2020, v. 34, n. 11, p. 15400, doi. 10.1096/fj.202000933RR
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- Publication type:
- Article
Combining gene mutation with gene expression data improves outcome prediction in myelodysplastic syndromes.
- Published in:
- Nature Communications, 2015, v. 6, n. 1, p. 5901, doi. 10.1038/ncomms6901
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- Publication type:
- Article
BCL-2 Inhibitor ABT-737 Effectively Targets Leukemia-Initiating Cells with Differential Regulation of Relevant Genes Leading to Extended Survival in a NRAS/BCL-2 Mouse Model of High Risk-Myelodysplastic Syndrome.
- Published in:
- International Journal of Molecular Sciences, 2021, v. 22, n. 19, p. 10658, doi. 10.3390/ijms221910658
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- Publication type:
- Article
Identification of acquired somatic mutations in the gene encoding chromatin-remodeling factor ATRX in the a-thalassemia myelodysplasia syndrome (ATMDS).
- Published in:
- Nature Genetics, 2003, v. 34, n. 4, p. 446, doi. 10.1038/ng1213
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- Publication type:
- Article
Disruption of SF3B1 results in deregulated expression and splicing of key genes and pathways in myelodysplastic syndrome hematopoietic stem and progenitor cells.
- Published in:
- Leukemia (08876924), 2015, v. 29, n. 8, p. 1798, doi. 10.1038/leu.2015.178
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- Publication type:
- Article
Disruption of SF3B1 results in deregulated expression and splicing of key genes and pathways in myelodysplastic syndrome hematopoietic stem and progenitor cells.
- Published in:
- Leukemia (08876924), 2015, v. 29, n. 5, p. 1092, doi. 10.1038/leu.2014.331
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- Publication type:
- Article
Whole-exome sequencing in del(5q) myelodysplastic syndromes in transformation to acute myeloid leukemia.
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- Leukemia (08876924), 2014, v. 28, n. 5, p. 1148, doi. 10.1038/leu.2013.381
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- Publication type:
- Article
Activation of the mTOR signaling pathway by L-leucine in 5q- syndrome and other RPS14-deficient erythroblasts.
- Published in:
- Leukemia (08876924), 2013, v. 27, n. 8, p. 1760, doi. 10.1038/leu.2013.20
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- Publication type:
- Article
Effects of L-leucine in 5q- syndrome and other RPS14-deficient erythroblasts.
- Published in:
- Leukemia (08876924), 2012, v. 26, n. 9, p. 2154, doi. 10.1038/leu.2012.82
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- Publication type:
- Article
High-density single nucleotide polymorphism array analysis and ASXL1 gene mutation screening in chronic myeloid leukemia during disease progression.
- Published in:
- Leukemia (08876924), 2010, v. 24, n. 6, p. 1139, doi. 10.1038/leu.2010.65
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- Publication type:
- Article
Frequent mutation of the polycomb-associated gene ASXL1 in the myelodysplastic syndromes and in acute myeloid leukemia.
- Published in:
- 2010
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- Publication type:
- Letter
Deregulated gene expression pathways in myelodysplastic syndrome hematopoietic stem cells.
- Published in:
- Leukemia (08876924), 2010, v. 24, n. 4, p. 756, doi. 10.1038/leu.2010.31
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- Publication type:
- Article
Cell-specific proteome analyses of human bone marrow reveal molecular features of age-dependent functional decline.
- Published in:
- Nature Communications, 2018, v. 9, n. 1, p. 1, doi. 10.1038/s41467-018-06353-4
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- Publication type:
- Article
Silencing of ASXL1 impairs the granulomonocytic lineage potential of human CD34<sup>+</sup> progenitor cells.
- Published in:
- British Journal of Haematology, 2013, v. 160, n. 6, p. 842, doi. 10.1111/bjh.12217
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- Publication type:
- Article
Marked down-regulation of nucleophosmin-1 is associated with advanced del(5q) myelodysplastic syndrome.
- Published in:
- British Journal of Haematology, 2011, v. 155, n. 2, p. 272, doi. 10.1111/j.1365-2141.2011.08672.x
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- Publication type:
- Article
Gene expression profiling of erythroblasts from refractory anaemia with ring sideroblasts (RARS) and effects of G-CSF.
- Published in:
- British Journal of Haematology, 2010, v. 149, n. 6, p. 844, doi. 10.1111/j.1365-2141.2010.08174.x
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- Publication type:
- Article
Marked downregulation of the granulopoiesis regulator LEF1 is associated with disease progression in the myelodysplastic syndromes.
- Published in:
- British Journal of Haematology, 2009, v. 146, n. 1, p. 86, doi. 10.1111/j.1365-2141.2009.07720.x
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- Publication type:
- Article
Haploinsufficiency of RPS14 in 5q− syndrome is associated with deregulation of ribosomal- and translation-related genes.
- Published in:
- British Journal of Haematology, 2008, v. 142, n. 1, p. 57, doi. 10.1111/j.1365-2141.2008.07178.x
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- Publication type:
- Article
Gene expression profiling of CD34<sup>+</sup> cells in patients with the 5q− syndrome.
- Published in:
- British Journal of Haematology, 2007, v. 139, n. 4, p. 578, doi. 10.1111/j.1365-2141.2007.06833.x
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- Publication type:
- Article
Low expression of the putative tumour suppressor gene gravin in chronic myeloid leukaemia, myelodysplastic syndromes and acute myeloid leukaemia.
- Published in:
- British Journal of Haematology, 2004, v. 126, n. 4, p. 508, doi. 10.1111/j.1365-2141.2004.05067.x
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- Publication type:
- Article
Gene expression profiling in the myelodysplastic syndromes using cDNA microarray technology.
- Published in:
- British Journal of Haematology, 2004, v. 125, n. 5, p. 576, doi. 10.1111/j.1365-2141.2004.04958.x
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- Publication type:
- Article
The molecular pathogenesis of the myelodysplastic syndromes.
- Published in:
- European Journal of Haematology, 2015, v. 95, n. 1, p. 3, doi. 10.1111/ejh.12515
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- Publication type:
- Article
Mutation Patterns of 16 Genes in Primary and Secondary Acute Myeloid Leukemia (AML) with Normal Cytogenetics.
- Published in:
- PLoS ONE, 2012, v. 7, n. 8, p. 1, doi. 10.1371/journal.pone.0042334
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- Publication type:
- Article
Meta-Analysis of Microarray Studies Reveals a Novel Hematopoietic Progenitor Cell Signature and Demonstrates Feasibility of Inter-Platform Data Integration.
- Published in:
- PLoS ONE, 2008, v. 3, n. 8, p. 1, doi. 10.1371/journal.pone.0002965
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- Publication type:
- Article
The Role of the Iron Transporter ABCB7 in Refractory Anemia with Ring Sideroblasts.
- Published in:
- PLoS ONE, 2008, v. 3, n. 4, p. 1, doi. 10.1371/journal.pone.0001970
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- Publication type:
- Article
Downregulation of Protection of Telomeres 1 expression in myelodysplastic syndromes with 7q deletion.
- Published in:
- British Journal of Haematology, 2016, v. 173, n. 1, p. 161, doi. 10.1111/bjh.13574
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- Publication type:
- Article
CSNK1A1 mutations and gene expression analysis in myelodysplastic syndromes with del(5q).
- Published in:
- British Journal of Haematology, 2015, v. 171, n. 2, p. 210, doi. 10.1111/bjh.13563
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- Publication type:
- Article
Mutations in SETBP1 are recurrent in myelodysplastic syndromes and often coexist with cytogenetic markers associated with disease progression.
- Published in:
- British Journal of Haematology, 2013, v. 163, n. 2, p. 235, doi. 10.1111/bjh.12491
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- Publication type:
- Article
High and low, but not intermediate, PRAME expression levels are poor prognostic markers in myelodysplastic syndrome at disease presentation.
- Published in:
- British Journal of Haematology, 2013, v. 162, n. 2, p. 282, doi. 10.1111/bjh.12352
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- Publication type:
- Article
Application of CRISPR/Cas9 genome editing to the study and treatment of disease.
- Published in:
- Archives of Toxicology, 2015, v. 89, n. 7, p. 1023, doi. 10.1007/s00204-015-1504-y
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- Publication type:
- Article
The U2AF1S34F mutation induces lineage-specific splicing alterations in myelodysplastic syndromes.
- Published in:
- 2017
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- Publication type:
- journal article
The U2AF1S34F mutation induces lineage-specific splicing alterations in myelodysplastic syndromes.
- Published in:
- 2017
- By:
- Publication type:
- journal article
Activation of targetable inflammatory immune signaling is seen in myelodysplastic syndromes with SF3B1 mutations.
- Published in:
- eLife, 2022, p. 1, doi. 10.7554/eLife.78136
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- Publication type:
- Article
Molecular analysis of the TFR2 gene: Report of a novel polymorphism (1878C>T).
- Published in:
- Human Mutation, 2000, v. 16, n. 6, p. 532, doi. 10.1002/1098-1004(200012)16:6<532::AID-HUMU17>3.0.CO;2-V
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- Publication type:
- Article
A novel polymorphism (219G>A) in the transferrin receptor gene.
- Published in:
- Human Mutation, 2000, v. 15, n. 4, p. 389, doi. 10.1002/(SICI)1098-1004(200004)15:4<389::AID-HUMU28>3.0.CO;2-H
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- Publication type:
- Article
Generalized mixed‐effects random forest: A flexible approach to predict university student dropout.
- Published in:
- Statistical Analysis & Data Mining, 2021, v. 14, n. 3, p. 241, doi. 10.1002/sam.11505
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- Publication type:
- Article
Reduced translation of GATA1 in Diamond-Blackfan anemia.
- Published in:
- Nature Medicine, 2014, v. 20, n. 7, p. 703, doi. 10.1038/nm.3630
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- Publication type:
- Article
Expression of CDKN1C in the bone marrow of patients with myelodysplastic syndrome and secondary acute myeloid leukemia is associated with poor survival after conventional chemotherapy.
- Published in:
- International Journal of Cancer, 2016, v. 139, n. 6, p. 1402, doi. 10.1002/ijc.30181
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- Publication type:
- Article
A miRNA screening identifies miR-192-5p as associated with response to azacitidine and lenalidomide therapy in myelodysplastic syndromes.
- Published in:
- Clinical Epigenetics, 2023, v. 15, n. 1, p. 1, doi. 10.1186/s13148-023-01441-9
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- Publication type:
- Article