Found: 4

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  • A General Strategy for Targeting Drugs to Bone.

    Published in:
    Angewandte Chemie International Edition, 2015, v. 54, n. 48, p. 14575, doi. 10.1002/anie.201507064
    By:
    • Jahnke, Wolfgang;
    • Bold, Guido;
    • Marzinzik, Andreas L.;
    • Ofner, Silvio;
    • Pellé, Xavier;
    • Cotesta, Simona;
    • Bourgier, Emmanuelle;
    • Lehmann, Sylvie;
    • Henry, Chrystelle;
    • Hemmig, René;
    • Stauffer, Frédéric;
    • Hartwieg, J. Constanze D.;
    • Green, Jonathan R.;
    • Rondeau, Jean‐Michel
    Publication type:
    Article

  • Gezielte Anreicherung von Wirkstoffen am Knochen am Beispiel von allosterischen FPPS-Inhibitoren.

    Published in:
    Angewandte Chemie, 2015, v. 127, n. 48, p. 14783, doi. 10.1002/ange.201507064
    By:
    • Jahnke, Wolfgang;
    • Bold, Guido;
    • Marzinzik, Andreas L.;
    • Ofner, Silvio;
    • Pellé, Xavier;
    • Cotesta, Simona;
    • Bourgier, Emmanuelle;
    • Lehmann, Sylvie;
    • Henry, Chrystelle;
    • Hemmig, René;
    • Stauffer, Frédéric;
    • Hartwieg, J. Constanze D.;
    • Green, Jonathan R.;
    • Rondeau, Jean ‐ Michel
    Publication type:
    Article

  • Discovery of Novel Allosteric Non-Bisphosphonate Inhibitors of Farnesyl Pyrophosphate Synthase by Integrated Lead Finding.

    Published in:
    ChemMedChem, 2015, v. 10, n. 11, p. 1884, doi. 10.1002/cmdc.201500338
    By:
    • Marzinzik, Andreas L.;
    • Amstutz, René;
    • Bold, Guido;
    • Bourgier, Emmanuelle;
    • Cotesta, Simona;
    • Glickman, J. Fraser;
    • Götte, Marjo;
    • Henry, Christelle;
    • Lehmann, Sylvie;
    • Hartwieg, J. Constanze D.;
    • Ofner, Silvio;
    • Pellé, Xavier;
    • Roddy, Thomas P.;
    • Rondeau, Jean‐Michel;
    • Stauffer, Frédéric;
    • Stout, Steven J.;
    • Widmer, Armin;
    • Zimmermann, Johann;
    • Zoller, Thomas;
    • Jahnke, Wolfgang
    Publication type:
    Article

  • Allosteric non-bisphosphonate FPPS inhibitors identified by fragment-based discovery.

    Published in:
    Nature Chemical Biology, 2010, v. 6, n. 9, p. 660, doi. 10.1038/nchembio.421
    By:
    • Jahnke, Wolfgang;
    • Rondeau, Jean-Michel;
    • Cotesta, Simona;
    • Marzinzik, Andreas;
    • Pellé, Xavier;
    • Geiser, Martin;
    • Strauss, André;
    • Götte, Marjo;
    • Bitsch, Francis;
    • Hemmig, René;
    • Henry, Chrystèle;
    • Lehmann, Sylvie;
    • Glickman, J Fraser;
    • Roddy, Thomas P;
    • Stout, Steven J;
    • Green, Jonathan R
    Publication type:
    Article