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Safe eradication of large established tumors using neovasculature‐targeted tumor necrosis factor‐based therapies.
Published in:
EMBO Molecular Medicine, 2020, v. 12, n. 2, p. N.PAG, doi. 10.15252/emmm.201911223
By:
- Huyghe, Leander;
- Van Parys, Alexander;
- Cauwels, Anje;
- Van Lint, Sandra;
- De Munter, Stijn;
- Bultinck, Jennyfer;
- Zabeau, Lennart;
- Hostens, Jeroen;
- Goethals, An;
- Vanderroost, Nele;
- Verhee, Annick;
- Uzé, Gilles;
- Kley, Niko;
- Peelman, Frank;
- Vandekerckhove, Bart;
- Brouckaert, Peter;
- Tavernier, Jan
Publication type:
Article
The Small GTPase Arf6: An Overview of Its Mechanisms of Action and of Its Role in Host–Pathogen Interactions and Innate Immunity.
Published in:
International Journal of Molecular Sciences, 2019, v. 20, n. 9, p. 2209, doi. 10.3390/ijms20092209
By:
- Van Acker, Tim;
- Tavernier, Jan;
- Peelman, Frank
Publication type:
Article
Straightforward Protein-Protein Interaction Interface Mapping via Random Mutagenesis and Mammalian Protein Protein Interaction Trap (MAPPIT).
Published in:
International Journal of Molecular Sciences, 2019, v. 20, n. 9, p. 2058, doi. 10.3390/ijms20092058
By:
- Vyncke, Laurens;
- Masschaele, Delphine;
- Tavernier, Jan;
- Peelman, Frank
Publication type:
Article
Definition of the interacting interfaces of Apobec3G and HIV-1 Vif using MAPPIT mutagenesis analysis.
Published in:
Nucleic Acids Research, 2010, v. 38, n. 6, p. 1902, doi. 10.1093/nar/gkp1154
By:
- Lavens, Delphine;
- Peelman, Frank;
- Van der Heyden, José;
- Uyttendaele, Isabel;
- Catteeuw, Dominiek;
- Verhee, Annick;
- Van Schoubroeck, Bertrand;
- Kurth, Julia;
- Hallenberger, Sabine;
- Clayton, Reginald;
- Tavernier, Jan
Publication type:
Article
Structural basis of the proinflammatory signaling complex mediated by TSLP.
Published in:
Nature Structural & Molecular Biology, 2014, v. 21, n. 4, p. 375, doi. 10.1038/nsmb.2794
By:
- Verstraete, Kenneth;
- van Schie, Loes;
- Vyncke, Laurens;
- Bloch, Yehudi;
- Tavernier, Jan;
- Pauwels, Ewald;
- Peelman, Frank;
- Savvides, Savvas N
Publication type:
Article
Random Mutagenesis MAPPIT Analysis Identifies Binding Sites for Vif and Gag in Both Cytidine Deaminase Domains of Apobec3G.
Published in:
PLoS ONE, 2012, v. 7, n. 9, p. 1, doi. 10.1371/journal.pone.0044143
By:
- Uyttendaele, Isabel;
- Lavens, Delphine;
- Catteeuw, Dominiek;
- Lemmens, Irma;
- Bovijn, Celia;
- Tavernier, Jan;
- Peelman, Frank;
- Fraternali, Franca
Publication type:
Article
HyperISGylation of Old World Monkey ISG15 in Human.
Published in:
PLoS ONE, 2008, v. 3, n. 6, p. 1, doi. 10.1371/journal.pone.0002427
By:
- Pattyn, Els;
- Verhee, Annick;
- Uyttendaele, Isabel;
- Piessevaux, Julie;
- Timmerman, Evy;
- Gevaert, Kris;
- Vandekerckhove, Joë l.;
- Peelman, Frank;
- Tavernier, Jan
Publication type:
Article
Biallelic RXFP2 variants lead to congenital bilateral cryptorchidism and male infertility, supporting a role of RXFP2 in spermatogenesis.
Published in:
Human Reproduction, 2024, v. 39, n. 10, p. 2353, doi. 10.1093/humrep/deae195
By:
- Syryn, Hannes;
- Velde, Julie Van de;
- Clercq, Griet De;
- Verdin, Hannah;
- Dheedene, Annelies;
- Peelman, Frank;
- Sinclair, Andrew;
- Ayers, Katie L;
- Bathgate, Ross A D;
- Cools, Martine;
- Baere, Elfride De
Publication type:
Article
Leptin's metabolic and immune functions can be uncoupled at the ligand/receptor interaction level.
Published in:
Cellular & Molecular Life Sciences, 2015, v. 72, n. 3, p. 629, doi. 10.1007/s00018-014-1697-x
By:
- Zabeau, Lennart;
- Jensen, Cathy;
- Seeuws, Sylvie;
- Venken, Koen;
- Verhee, Annick;
- Catteeuw, Dominiek;
- Loo, Geert;
- Chen, Hui;
- Walder, Ken;
- Hollis, Jacob;
- Foote, Simon;
- Morris, Margaret;
- Heyden, José;
- Peelman, Frank;
- Oldfield, Brian;
- Rubio, Justin;
- Elewaut, Dirk;
- Tavernier, Jan
Publication type:
Article
Structure and antagonism of the receptor complex mediated by human TSLP in allergy and asthma.
Published in:
Nature Communications, 2017, v. 8, n. 4, p. 14937, doi. 10.1038/ncomms14937
By:
- Verstraete, Kenneth;
- Peelman, Frank;
- Braun, Harald;
- Lopez, Juan;
- Van Rompaey, Dries;
- Dansercoer, Ann;
- Vandenberghe, Isabel;
- Pauwels, Kris;
- Tavernier, Jan;
- Lambrecht, Bart N.;
- Hammad, Hamida;
- De Winter, Hans;
- Beyaert, Rudi;
- Lippens, Guy;
- Savvides, Savvas N.
Publication type:
Article
Specific targeting of IL-1β activity to CD8+ T cells allows for safe use as a vaccine adjuvant.
Published in:
NPJ Vaccines, 2020, v. 5, n. 1, p. 1, doi. 10.1038/s41541-020-00211-5
By:
- Van Den Eeckhout, Bram;
- Van Hoecke, Lien;
- Burg, Elianne;
- Van Lint, Sandra;
- Peelman, Frank;
- Kley, Niko;
- Uzé, Gilles;
- Saelens, Xavier;
- Tavernier, Jan;
- Gerlo, Sarah
Publication type:
Article
The Biologist's Guide to the Glucocorticoid Receptor's Structure.
Published in:
Cells (2073-4409), 2023, v. 12, n. 12, p. 1636, doi. 10.3390/cells12121636
By:
- Deploey, Nick;
- Van Moortel, Laura;
- Rogatsky, Inez;
- Peelman, Frank;
- De Bosscher, Karolien
Publication type:
Article
Functional characterization of the first missense variant in CEP78, a founder allele associated with cone‐rod dystrophy, hearing loss, and reduced male fertility.
Published in:
Human Mutation, 2020, v. 41, n. 5, p. 998, doi. 10.1002/humu.23993
By:
- Ascari, Giulia;
- Peelman, Frank;
- Farinelli, Pietro;
- Rosseel, Toon;
- Lambrechts, Nina;
- Wunderlich, Kirsten A.;
- Wagner, Matias;
- Nikopoulos, Konstantinos;
- Martens, Pernille;
- Balikova, Irina;
- Derycke, Lara;
- Holtappels, Gabriële;
- Krysko, Olga;
- Van Laethem, Thalia;
- De Jaegere, Sarah;
- Guillemyn, Brecht;
- De Rycke, Riet;
- De Bleecker, Jan;
- Creytens, David;
- Van Dorpe, Jo
Publication type:
Article
The N‐terminal p.(Ser38Cys) TIMP3 mutation underlying Sorsby fundus dystrophy is a founder mutation disrupting an intramolecular disulfide bond.
Published in:
Human Mutation, 2019, v. 40, n. 5, p. 539, doi. 10.1002/humu.23713
By:
- Naessens, Sarah;
- Zaeytijd, Julie;
- Syx, Delfien;
- Vandenbroucke, Roosmarijn E.;
- Smeets, Frédéric;
- Cauwenbergh, Caroline;
- Leroy, Bart P.;
- Peelman, Frank;
- Coppieters, Frauke
Publication type:
Article
High prevalence of mutations in LCAT in patients with low HDL cholesterol levels in the Netherlands: Identification and characterization of eight novel mutations.
Published in:
Human Mutation, 2011, v. 32, n. 11, p. 1290, doi. 10.1002/humu.21578
By:
- Holleboom, Adriaan G.;
- Kuivenhoven, Jan A.;
- Peelman, Frank;
- Schimmel, Alinda W.;
- Peter, Jorge;
- Defesche, Joep C.;
- Kastelein, John J.P.;
- Hovingh, G. Kees;
- Stroes, Erik S.;
- Motazacker, Mohammad Mahdi
Publication type:
Article
MAPPIT analysis of TLR adaptor complexes
Published in:
FEBS Letters, 2007, v. 581, n. 4, p. 629, doi. 10.1016/j.febslet.2007.01.026
By:
- Ulrichts, Peter;
- Peelman, Frank;
- Beyaert, Rudi;
- Tavernier, Jan
Publication type:
Article
The ins and outs of leptin receptor activation
Published in:
FEBS Letters, 2003, v. 546, n. 1, p. 45, doi. 10.1016/S0014-5793(03)00440-X
By:
- Zabeau, Lennart;
- Lavens, Delphine;
- Peelman, Frank;
- Eyckerman, Sven;
- Vandekerckhove, Joël;
- Tavernier, Jan
Publication type:
Article
RNF41 interacts with the VPS52 subunit of the GARP and EARP complexes.
Published in:
PLoS ONE, 2017, v. 12, n. 5, p. 1, doi. 10.1371/journal.pone.0178132
By:
- Masschaele, Delphine;
- De Ceuninck, Leentje;
- Wauman, Joris;
- Defever, Dieter;
- Stenner, Frank;
- Lievens, Sam;
- Peelman, Frank;
- Tavernier, Jan
Publication type:
Article
Definition of the interacting interfaces of Apobec3G and HIV-1 Vif using MAPPIT mutagenesis analysis.
Published in:
2010
By:
- Lavens, Delphine;
- Peelman, Frank;
- Van der Heyden, José;
- Uyttendaele, Isabel;
- Catteeuw1,2,, Dominiek;
- Van Schouwbroeck, Bertrand;
- Kurth, Julia;
- Hallenberger, Sabine;
- Clayton, Reginald;
- Tavernier, Jan
Publication type:
Abstract
Antagonizing leptin: current status and future directions.
Published in:
Biological Chemistry, 2014, v. 395, n. 5, p. 599, doi. 10.1515/hsz-2013-0283
By:
- Zabeau, Lennart;
- Peelman, Frank;
- Tavernier, Jan
Publication type:
Article

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