Works by Pavlov, Evgeny V.

Results: 28

Depletion of mitochondrial inorganic polyphosphate (polyP) in mammalian cells causes metabolic shift from oxidative phosphorylation to glycolysis.

Published in:

Biochemical Journal, 2021, v. 478, n. 8, p. 1631, doi. 10.1042/BCJ20200975

By:

Solesio, Maria E.;
Lihan Xie;
McIntyre, Brendan;
Ellenberger, Mathew;
Mitaishvili, Erna;
Bhadra-Lobo, Siddharth;
Bettcher, Lisa F.;
Bazil, Jason N.;
Raftery, Daniel;
Jakob, Ursula;
Pavlov, Evgeny V.

Publication type:

Article

Tamoxifen-induced knockdown of the mitochondrial calcium uniporter in Thy1-expressing neurons protects mice from hypoxic/ischemic brain injury.

Published in:

Cell Death & Disease, 2018, v. 9, n. 6, p. 1, doi. 10.1038/s41419-018-0607-9

By:

Nichols, Matthew;
Pavlov, Evgeny V.;
Robertson, George S.

Publication type:

Article

From ATP synthase dimers to C-ring conformational changes: unified model of the mitochondrial permeability transition pore.

Published in:

Cell Death & Disease, 2017, v. 8, n. 12, p. 1, doi. 10.1038/s41419-017-0042-3

By:

Amodeo, Giuseppe Federico;
Solesio, Maria E.;
Pavlov, Evgeny V.

Publication type:

Article

Inorganic polyphosphate regulates neuronal excitability through modulation of voltage-gated channels.

Published in:

Molecular Brain, 2014, v. 7, n. 1, p. 1, doi. 10.1186/1756-6606-7-42

By:

Stotz, Stephanie C.;
Scott, Lucas O. M.;
Drummond-Main, Christopher;
Avchalumov, Yosef;
Girotto, Fernando;
Davidsen, Jö rn;
Gómez-Gárcia, Maria Rosario;
Rho, Jong M.;
Pavlov, Evgeny V.;
Colicos, Michael A.

Publication type:

Article

Mitochondrial inorganic polyphosphate is required to maintain proteostasis within the organelle.

Published in:

Frontiers in Cell & Developmental Biology, 2024, p. 1, doi. 10.3389/fcell.2024.1423208

By:

Da Costa, Renata T.;
Urquiza, Pedro;
Perez, Matheus M.;
YunGuang Du;
Mei Li Khong;
Haiyan Zheng;
Guitart-Mampel, Mariona;
Elustondo, Pia A.;
Scoma, Ernest R.;
Hambardikar, Vedangi;
Ueberheide, Beatrix;
Tanner, Julian A.;
Cohen, Alejandro;
Pavlov, Evgeny V.;
Haynes, Cole M.;
Solesio, Maria E.

Publication type:

Article

Polyhydroxybutyrate Targets Mammalian Mitochondria and Increases Permeability of Plasmalemmal and Mitochondrial Membranes.

Published in:

PLoS ONE, 2013, v. 8, n. 9, p. 1, doi. 10.1371/journal.pone.0075812

By:

Elustondo, Pia A.;
Angelova, Plamena R.;
Kawalec, Michał;
Michalak, Michał;
Kurcok, Piotr;
Abramov, Andrey Y.;
Pavlov, Evgeny V.

Publication type:

Article

Distinct mPTP activation mechanisms in ischaemia-reperfusion: contributions of Ca<sup>2+</sup>, ROS, pH, and inorganic polyphosphate.

Published in:

Cardiovascular Research, 2015, v. 106, n. 2, p. 237, doi. 10.1093/cvr/cvv097

By:

Seidlmayer, Lea K.;
Juettner, Vanessa V.;
Kettlewell, Sarah;
Pavlov, Evgeny V.;
Blatter, Lothar A.;
Dedkova, Elena N.

Publication type:

Article

TRPM8 as the rapid testosterone signaling receptor: Implications in the regulation of dimorphic sexual and social behaviors.

Published in:

FASEB Journal, 2020, v. 34, n. 8, p. 10887, doi. 10.1096/fj.202000794R

By:

Mohandass, Adithya;
Krishnan, Vivek;
Gribkova, Ekaterina D.;
Asuthkar, Swapna;
Baskaran, Padmamalini;
Nersesyan, Yelena;
Hussain, Zahir;
Wise, Leslie M.;
George, Robert E.;
Stokes, Nadarra;
Alexander, Brenda M.;
Cohen, Alejandro M.;
Pavlov, Evgeny V.;
Llano, Daniel A.;
Zhu, Michael X.;
Thyagarajan, Baskaran;
Zakharian, Eleonora

Publication type:

Article

Adenosine A2A receptor (A2AR) stimulation enhances mitochondrial metabolism and mitigates reactive oxygen species‐mediated mitochondrial injury.

Published in:

FASEB Journal, 2020, v. 34, n. 4, p. 5027, doi. 10.1096/fj.201902459R

By:

Castro, Cristina M.;
Corciulo, Carmen;
Solesio, Maria E.;
Liang, Fengxia;
Pavlov, Evgeny V.;
Cronstein, Bruce N.

Publication type:

Article

Calculation of ion currents across the inner membrane of functionally intact mitochondria.

Published in:

Channels (19336950), 2013, v. 7, n. 6, p. 1, doi. 10.4161/chan.26290

By:

Kane, Daniel A;
Pavlov, Evgeny V

Publication type:

Article

α-synuclein Oligomers Interact With ATP Synthase and Open the Permeability Transition Pore in Parkinson's Disease.

Published in:

Nature Communications, 2018, v. 9, n. 1, p. 1, doi. 10.1038/s41467-018-04422-2

By:

Ludtmann, Marthe H.R.;
Angelova, Plamena R.;
Horrocks, Mathew H.;
Choi, Minee L.;
Rodrigues, Margarida;
Baev, Artyom Y.;
Berezhnov, Alexey V.;
Zhi Yao;
Little, Daniel;
Banushi, Blerida;
Al-Menhali, Afnan Saleh;
Ranasinghe, Rohan T.;
Whiten, Daniel R.;
Yapom, Ratsuda;
Dolt, Karamjit Singh;
Devine, Michael J.;
Gissen, Paul;
Kunath, Tilo;
Jaganjac, Morana;
Pavlov, Evgeny V.

Publication type:

Article

The cell-permeable mitochondrial calcium uniporter inhibitor Ru265 preserves cortical neuron respiration after lethal oxygen glucose deprivation and reduces hypoxic/ischemic brain injury.

Published in:

Journal of Cerebral Blood Flow & Metabolism, 2020, v. 40, n. 6, p. 1172, doi. 10.1177/0271678X20908523

By:

Novorolsky, Robyn J;
Nichols, Matthew;
Kim, Jong S;
Pavlov, Evgeny V;
J Woods, Joshua;
Wilson, Justin J;
Robertson, George S

Publication type:

Article

Global ablation of the mitochondrial calcium uniporter increases glycolysis in cortical neurons subjected to energetic stressors.

Published in:

Journal of Cerebral Blood Flow & Metabolism, 2017, v. 37, n. 8, p. 3027, doi. 10.1177/0271678X16682250

By:

Nichols, Matthew;
Elustondo, Pia A.;
Warford, Jordan;
Thirumaran, Aruloli;
Pavlov, Evgeny V.;
Robertson, George S.

Publication type:

Article

Insoluble tau aggregates induce neuronal death through modification of membrane ion conductance, activation of voltage‐gated calcium channels and NADPH oxidase.

Published in:

FEBS Journal, 2021, v. 288, n. 1, p. 127, doi. 10.1111/febs.15340

By:

Esteras, Noemi;
Kundel, Franziska;
Amodeo, Giuseppe F.;
Pavlov, Evgeny V.;
Klenerman, David;
Abramov, Andrey Y.

Publication type:

Article

Inorganic polyphosphate controls cyclophilin B‐mediated collagen folding in osteoblast‐like cells.

Published in:

FEBS Journal, 2020, v. 287, n. 20, p. 4500, doi. 10.1111/febs.15249

By:

Khong, Mei Li;
Li, Lina;
Solesio, Maria E.;
Pavlov, Evgeny V.;
Tanner, Julian A.

Publication type:

Article

C subunit of the ATP synthase is an amyloidogenic calcium dependent channel-forming peptide with possible implications in mitochondrial permeability transition.

Published in:

Scientific Reports, 2021, v. 11, n. 1, p. 1, doi. 10.1038/s41598-021-88157-z

By:

Amodeo, Giuseppe Federico;
Lee, Brenda Yasie;
Krilyuk, Natalya;
Filice, Carina Teresa;
Valyuk, Denis;
Otzen, Daniel Erik;
Noskov, Sergey;
Leonenko, Zoya;
Pavlov, Evgeny V.

Publication type:

Article

The mitochondrial permeability transition phenomenon elucidated by cryo-EM reveals the genuine impact of calcium overload on mitochondrial structure and function.

Published in:

Scientific Reports, 2021, v. 11, n. 1, p. 1, doi. 10.1038/s41598-020-80398-8

By:

Strubbe-Rivera, Jasiel O.;
Schrad, Jason R.;
Pavlov, Evgeny V.;
Conway, James F.;
Parent, Kristin N.;
Bazil, Jason N.

Publication type:

Article

Inorganic polyphosphate (polyP) as an activator and structural component of the mitochondrial permeability transition pore.

Published in:

Biochemical Society Transactions, 2016, v. 44, n. 1, p. 7, doi. 10.1042/BST20150206

By:

Solesio, Maria E.;
Elustondo, Pia A.;
Zakharian, Eleonora;
Pavlov, Evgeny V.

Publication type:

Article

Mitochondrial Function Is Compromised in Cortical Bone Osteocytes of Long‐Lived Growth Hormone Receptor Null Mice.

Published in:

Journal of Bone & Mineral Research, 2019, v. 34, n. 1, p. 106, doi. 10.1002/jbmr.3573

By:

Liu, Zhongbo;
Solesio, Maria E;
Schaffler, Mitchell B;
Frikha‐Benayed, Dorra;
Rosen, Clifford J;
Werner, Haim;
Kopchick, John J;
Pavlov, Evgeny V;
Abramov, Andrey Y;
Yakar, Shoshana

Publication type:

Article

Investigation of Properties of the Mitochondrial Permeability Transition Pore Using Whole-Mitoplast Patch-Clamp Technique.

Published in:

DNA & Cell Biology, 2023, v. 42, n. 8, p. 481, doi. 10.1089/dna.2023.0171

By:

Neginskaya, Maria A.;
Pavlov, Evgeny V.

Publication type:

Article

A novel, high conductance channel of mitochondria linked to apoptosis in mammalian cells and Bax....

Published in:

Journal of Cell Biology, 2001, v. 155, n. 5, p. 725, doi. 10.1083/jcb.200107057

By:

Pavlov, Evgeny V.;
Priault, Muriel;
Pietkiewicz, Dawn;
Cheng, Emily H.-Y.;
Antonsson, Bruno;
Manon, Stephen;
Korsmeyer, Stanley J.;
Mannella, Carmen A.;
Kinnally, Kathleen W.

Publication type:

Article

Refractive Index Imaging Reveals That Elimination of the ATP Synthase C Subunit Does Not Prevent the Adenine Nucleotide Translocase-Dependent Mitochondrial Permeability Transition.

Published in:

Cells (2073-4409), 2023, v. 12, n. 15, p. 1950, doi. 10.3390/cells12151950

By:

Neginskaya, Maria A.;
Morris, Sally E.;
Pavlov, Evgeny V.

Publication type:

Article

Mitochondrial Permeability Transition: A Pore Intertwines Brain Aging and Alzheimer's Disease.

Published in:

Cells (2073-4409), 2021, v. 10, n. 3, p. 649, doi. 10.3390/cells10030649

By:

Jia, Kun;
Du, Heng;
Bernardi, Paolo;
Pavlov, Evgeny V.

Publication type:

Article

Genetic Approach to Elucidate the Role of Cyclophilin D in Traumatic Brain Injury Pathology.

Published in:

Cells (2073-4409), 2021, v. 10, n. 2, p. 199, doi. 10.3390/cells10020199

By:

Readnower, Ryan D.;
Hubbard, William Brad;
Kalimon, Olivia J.;
Geddes, James W.;
Sullivan, Patrick G.;
Bernadi, Paolo;
Pavlov, Evgeny V.

Publication type:

Article

Mitochondrial Cyclosporine A-Independent Palmitate/Ca 2+ -Induced Permeability Transition Pore (PA-mPT Pore) and Its Role in Mitochondrial Function and Protection against Calcium Overload and Glutamate Toxicity.

Published in:

Cells (2073-4409), 2021, v. 10, n. 1, p. 125, doi. 10.3390/cells10010125

By:

Mironova, Galina D.;
Pavlov, Evgeny V.

Publication type:

Article

Formation of High-Conductive C Subunit Channels upon Interaction with Cyclophilin D.

Published in:

International Journal of Molecular Sciences, 2021, v. 22, n. 20, p. 11022, doi. 10.3390/ijms222011022

By:

Amodeo, Giuseppe Federico;
Krilyuk, Natalya;
Pavlov, Evgeny V.

Publication type:

Article

Effects of lithium isotopes on sodium/lithium co-transport and calcium efflux through the sodium/calcium/lithium exchanger in mitochondria.

Published in:

Frontiers in Physiology, 2024, p. 01, doi. 10.3389/fphys.2024.1354091

By:

Bukhteeva, Irina;
Rahman, Fasih A.;
Kendall, Brian;
Duncan, Robin E.;
Quadrilatero, Joe;
Pavlov, Evgeny V.;
Gingras, Michel J. P.;
Leonenko, Zoya

Publication type:

Article

Carbonic anhydrase inhibition selectively prevents amyloid β neurovascular mitochondrial toxicity.

Published in:

Aging Cell, 2018, v. 17, n. 4, p. 1, doi. 10.1111/acel.12787

By:

Solesio, María E.;
Peixoto, Pablo M.;
Debure, Ludovic;
Madamba, Stephen M.;
de Leon, Mony J.;
Wisniewski, Thomas;
Pavlov, Evgeny V.;
Fossati, Silvia

Publication type:

Article