Works by Paus, Ralf

Results: 347

Preclinical Evidence That Mesoglycan Unfolds Complex Anti-Aging Effects in Photoaged Female Facial Skin.

Published in:

International Journal of Molecular Sciences, 2025, v. 26, n. 12, p. 5787, doi. 10.3390/ijms26125787

By:

Zeltzer, Assaf;
Keren, Aviad;
Paus, Ralf;
Gilhar, Amos

Publication type:

Article

Macrophages Contribute to the Cyclic Activation of Adult Hair Follicle Stem Cells.

Published in:

PLoS Biology, 2014, v. 12, n. 12, p. 1, doi. 10.1371/journal.pbio.1002002

By:

Castellana, Donatello;
Paus, Ralf;
Perez-Moreno, Mirna

Publication type:

Article

Melatonin: A Potential Regulator of DNA Methylation.

Published in:

Antioxidants, 2023, v. 12, n. 6, p. 1155, doi. 10.3390/antiox12061155

By:

Linowiecka, Kinga;
Slominski, Andrzej T.;
Reiter, Russel J.;
Böhm, Markus;
Steinbrink, Kerstin;
Paus, Ralf;
Kleszczyński, Konrad

Publication type:

Article

2,4,6-Octatrienoic acid is a novel promoter of melanogenesis and antioxidant defence in normal human melanocytes via PPAR-γ activation.

Published in:

Pigment Cell & Melanoma Research, 2011, v. 24, n. 4, p. 618, doi. 10.1111/j.1755-148X.2011.00887.x

By:

Flori, Enrica;
Mastrofrancesco, Arianna;
Kovacs, Daniela;
Ramot, Yuval;
Briganti, Stefania;
Bellei, Barbara;
Paus, Ralf;
Picardo, Mauro

Publication type:

Article

A neuroendocrinological perspective on human hair follicle pigmentation.

Published in:

Pigment Cell & Melanoma Research, 2011, v. 24, n. 1, p. 89, doi. 10.1111/j.1755-148X.2010.00808.x

By:

Paus, Ralf

Publication type:

Article

Dominant frontonasal dysplasia with ectodermal defects results from increased activity of ALX4.

Published in:

American Journal of Medical Genetics. Part A, 2023, v. 191, n. 12, p. 2806, doi. 10.1002/ajmg.a.63408

By:

Peled, Alon;
Sarig, Ofer;
Mohamad, Janan;
Eskin‐Schwartz, Marina;
Vodo, Dan;
Bochner, Ron;
Malchin, Natalya;
Isakov, Ofer;
Shomron, Noam;
Fainberg, Gilad;
Bertolini, Marta;
Paus, Ralf;
Sprecher, Eli

Publication type:

Article

Developmental timing of hair follicle and dorsal skin innervation in mice.

Published in:

Journal of Comparative Neurology, 2002, v. 448, n. 1, p. 28, doi. 10.1002/cne.10212

By:

Peters, Eva M.J.;
Botchkarev, Vladimir A.;
Müller-Röver, Sven;
Moll, Ingrid;
Rice, Frank L.;
Paus, Ralf

Publication type:

Article

Hair cycle-dependent plasticity of skin and hair follicle innervation in normal murine skin.

Published in:

Journal of Comparative Neurology, 1997, v. 386, n. 3, p. 379, doi. 10.1002/(SICI)1096-9861(19970929)386:3<379::AID-CNE4>3.0.CO;2-Z

By:

Botchkarev, Vladimir A.;
Eichmüller, Stefan;
Johansson, Olle;
Paus, Ralf

Publication type:

Article

A plaidoyer for the use of human skin xenotransplant mouse models in preclinical psoriasis research.

Published in:

Journal of the European Academy of Dermatology & Venereology, 2023, v. 37, n. 3, p. e406, doi. 10.1111/jdv.18644

By:

Gilhar, Amos;
Reich, Kristian;
Keren, Aviad;
Paus, Ralf

Publication type:

Article

The role of P-cadherin in skin biology and skin pathology: lessons from the hair follicle.

Published in:

Cell & Tissue Research, 2015, v. 360, n. 3, p. 761, doi. 10.1007/s00441-015-2114-y

By:

Samuelov, Liat;
Sprecher, Eli;
Paus, Ralf

Publication type:

Article

Deciphering the functions of the hair follicle infundibulum in skin physiology and disease.

Published in:

Cell & Tissue Research, 2014, v. 358, n. 3, p. 697, doi. 10.1007/s00441-014-1999-1

By:

Schneider, Marlon;
Paus, Ralf

Publication type:

Article

Data assimilation of synthetic data as a novel strategy for predicting disease progression in alopecia areata.

Published in:

Mathematical Medicine & Biology: A Journal of the IMA, 2021, v. 38, n. 3, p. 314, doi. 10.1093/imammb/dqab008

By:

Cogan, NG;
Bao, Feng;
Paus, Ralf;
Dobreva, Atanaska

Publication type:

Article

Analysing the dynamics of a model for alopecia areata as an autoimmune disorder of hair follicle cycling.

Published in:

Mathematical Medicine & Biology: A Journal of the IMA, 2018, v. 35, n. 3, p. 387, doi. 10.1093/imammb/dqx009

By:

Dobreva, Atanaska;
Paus, Ralf;
Cogan, N G

Publication type:

Article

A Cell Membrane-Level Approach to Cicatricial Alopecia Management: Is Caveolin-1 a Viable Therapeutic Target in Frontal Fibrosing Alopecia?

Published in:

Biomedicines, 2021, v. 9, n. 5, p. 572, doi. 10.3390/biomedicines9050572

By:

Jozic, Ivan;
Chéret, Jérémy;
Abujamra, Beatriz Abdo;
Miteva, Mariya;
Gherardini, Jennifer;
Paus, Ralf;
Dell'Agli, Mario

Publication type:

Article

Hydra and the hair follicle – An unconventional comparative biology approach to exploring the human holobiont.

Published in:

BioEssays, 2022, v. 44, n. 5, p. 1, doi. 10.1002/bies.202100233

By:

Lousada, Marta B.;
Lachnit, Tim;
Edelkamp, Janin;
Paus, Ralf;
Bosch, Thomas C. G.

Publication type:

Article

Mitochondrially localized MPZL3 emerges as a signaling hub of mammalian physiology.

Published in:

BioEssays, 2021, v. 43, n. 10, p. 1, doi. 10.1002/bies.202100126

By:

Wikramanayake, Tongyu C.;
Nicu, Carina;
Chéret, Jérémy;
Czyzyk, Traci A.;
Paus, Ralf

Publication type:

Article

A folliculocentric perspective of dandruff pathogenesis: Could a troublesome condition be caused by changes to a natural secretory mechanism?

Published in:

BioEssays, 2021, v. 43, n. 10, p. 1, doi. 10.1002/bies.202100005

By:

Limbu, Susan L.;
Purba, Talveen S.;
Harries, Matthew;
Wikramanayake, Tongyu C.;
Miteva, Mariya;
Bhogal, Ranjit K.;
O'Neill, Catherine A.;
Paus, Ralf

Publication type:

Article

Tissue-resident macrophages can be generated de novo in adult human skin from resident progenitor cells during substance P-mediated neurogenic inflammation ex vivo.

Published in:

PLoS ONE, 2020, v. 15, n. 1, p. 1, doi. 10.1371/journal.pone.0227817

By:

Gherardini, Jennifer;
Uchida, Youhei;
Hardman, Jonathan A.;
Chéret, Jérémy;
Mace, Kimberly;
Bertolini, Marta;
Paus, Ralf

Publication type:

Article

Hair Follicle Bulge Stem Cells Appear Dispensable for the Acute Phase of Wound Re-epithelialization.

Published in:

Stem Cells, 2016, v. 34, n. 5, p. 1377, doi. 10.1002/stem.2289

By:

Garcin, Clare L.;
Hardman, Matthew J.;
Ansell, David M.;
Paus, Ralf;
Headon, Denis J.

Publication type:

Article

Circadian Clock Genes Contribute to the Regulation of Hair Follicle Cycling.

Published in:

PLoS Genetics, 2009, v. 5, n. 7, p. 1, doi. 10.1371/journal.pgen.1000573

By:

Lin, Kevin K.;
Kumar, Vivek;
Geyfman, Mikhail;
Chudova, Darya;
Ihler, Alexander T.;
Smyth, Padhraic;
Paus, Ralf;
Takahashi, Joseph S.;
Andersen, Bogi

Publication type:

Article

Cannabidiol exerts sebostatic and antiinflammatory effects on human sebocytes.

Published in:

2014

By:

Oláh, Attila;
Tóth, Balázs I;
Borbíró, István;
Sugawara, Koji;
Szöllõsi, Attila G;
Czifra, Gabriella;
Pál, Balázs;
Ambrus, Lídia;
Kloepper, Jennifer;
Camera, Emanuela;
Ludovici, Matteo;
Picardo, Mauro;
Voets, Thomas;
Zouboulis, Christos C;
Paus, Ralf;
Bíró, Tamás

Publication type:

journal article

Cannabidiol exerts sebostatic and antiinflammatory effects on human sebocytes.

Published in:

Journal of Clinical Investigation, 2014, v. 124, n. 9, p. 3713, doi. 10.1172/JCI64628

By:

Oláh, Attila;
Tóth, Balázs I.;
Borbíró, István;
Sugawara, Koji;
Szöllõsi, Attila G.;
Czifra, Gabriella;
Pál, Balázs;
Ambrus, Lídia;
Kloepper, Jennifer;
Camera, Emanuela;
Ludovici, Matteo;
Picardo, Mauro;
Voets, Thomas;
Zouboulis, Christos C.;
Paus, Ralf;
Bíró, Tamás

Publication type:

Article

Lymphocytes, neuropeptides, and genes involved in alopecia areata.

Published in:

Journal of Clinical Investigation, 2007, v. 117, n. 8, p. 2019, doi. 10.1172/JCI31942

By:

Gilhar, Amos;
Paus, Ralf;
Kalish, Richard S.

Publication type:

Article

Frontiers in pruritus research: scratching the brain for more effective itch therapy.

Published in:

2006

By:

Paus, Ralf;
Schmelz, Martin;
Bíró, Tamás;
Steinhoff, Martin;
Bíró, Tamás

Publication type:

journal article

Application of Topical Sandalore® Increases Epidermal Dermcidin Synthesis in Organ-Cultured Human Skin ex vivo.

Published in:

Skin Pharmacology & Physiology, 2023, v. 36, n. 3, p. 117, doi. 10.1159/000528402

By:

Edelkamp, Janin;
Lousada, Marta B.;
Pinto, Daniela;
Chéret, Jérémy;
O'Sullivan, James D.B.;
Biundo, Antonio;
Jimenez, Francisco;
Funk, Wolfgang;
Roessing, Christian;
Rippmann, Volker;
Paus, Ralf;
Bertolini, Marta

Publication type:

Article

Vascular Endothelial Growth Factor Blockade Induces Dermal Endothelial Cell Apoptosis in a Clinically Relevant Skin Organ Culture Model.

Published in:

Skin Pharmacology & Physiology, 2020, v. 33, n. 3, p. 110, doi. 10.1159/000508344

By:

Luengas-Martinez, Andrea;
Hardman-Smart, Jonathan;
Rutkowski, David;
Purba, Talveen S.;
Paus, Ralf;
Young, Helen S.

Publication type:

Article

Mineralocorticoid Receptor Antagonists Stimulate Human Hair Growth ex vivo.

Published in:

Skin Pharmacology & Physiology, 2019, v. 32, n. 6, p. 344, doi. 10.1159/000501729

By:

Hundt, Jennifer E.;
Sass, Stephanie;
Funk, Wolfgang;
Bíró, Tamás;
Farman, Nicolette;
Langan, Ewan A.;
Paus, Ralf

Publication type:

Article

„Vernarbende” Alopezien Anmerkungen zur Klassifikation, Differentialdiagnose und Pathobiologie.

Published in:

Der Hautarzt, 1998, v. 49, n. 6, p. 462, doi. 10.1007/s001050050771

By:

Hermes, Barbara;
Paus, Ralf

Publication type:

Article

Adiponectin negatively regulates pigmentation, Wnt/β-catenin and HGF/c-Met signalling within human scalp hair follicles ex vivo.

Published in:

Archives of Dermatological Research, 2023, v. 315, n. 3, p. 603, doi. 10.1007/s00403-021-02291-2

By:

Nicu, Carina;
Jackson, Jennifer;
Shahmalak, Asim;
Pople, Jenny;
Ansell, David;
Paus, Ralf

Publication type:

Article

Towards developing an organotypic model for the preclinical study and manipulation of human hair matrix-dermal papilla interactions.

Published in:

Archives of Dermatological Research, 2022, v. 314, n. 5, p. 491, doi. 10.1007/s00403-020-02178-8

By:

Platt, Christopher I.;
Chéret, Jeremy;
Paus, Ralf

Publication type:

Article

Nestin<sup>+</sup> progenitor cells isolated from adult human sweat gland stroma promote reepithelialisation and may stimulate angiogenesis in wounded human skin ex vivo.

Published in:

Archives of Dermatological Research, 2019, v. 311, n. 4, p. 325, doi. 10.1007/s00403-019-01889-x

By:

Liao, Tian;
Lehmann, Janin;
Sternstein, Sabine;
Yay, Arzu;
Zhang, Guoyou;
Matthießen, Anna Emilia;
Schumann, Sandra;
Siemers, Frank;
Kruse, Charli;
Hundt, Jennifer E.;
Langan, Ewan A.;
Tiede, Stephan;
Paus, Ralf

Publication type:

Article

Dermal white adipose tissue undergoes major morphological changes during the spontaneous and induced murine hair follicle cycling: a reappraisal.

Published in:

Archives of Dermatological Research, 2018, v. 310, n. 5, p. 453, doi. 10.1007/s00403-018-1831-y

By:

Foster, April R.;
Nicu, Carina;
Schneider, Marlon R.;
Hinde, Eleanor;
Paus, Ralf

Publication type:

Article

N-methylspermidine, a stable spermidine analog, prolongs anagen and regulates epithelial stem cell functions in human hair follicles.

Published in:

Archives of Dermatological Research, 2015, v. 307, n. 9, p. 841, doi. 10.1007/s00403-015-1592-9

By:

Ramot, Yuval;
Marzani, Barbara;
Pinto, Daniela;
Kloepper, Jennifer;
Paus, Ralf

Publication type:

Article

Topical odorant application of the specific olfactory receptor OR2AT4 agonist, Sandalore<sup>®</sup>, improves telogen effluvium‐associated parameters.

Published in:

Journal of Cosmetic Dermatology, 2021, v. 20, n. 3, p. 784, doi. 10.1111/jocd.13608

By:

Jimenez, Francisco;
López, Esmeralda;
Bertolini, Marta;
Alam, Majid;
Chéret, Jérémy;
Westgate, Gill;
Rinaldi, Fabio;
Marzani, Barbara;
Paus, Ralf

Publication type:

Article

Re-Evaluating Cyclosporine A as a Hair Growth-Promoting Agent in Human Scalp Hair Follicles.

Published in:

Journal of Investigative Dermatology, 2015, v. 135, n. 8, p. 2129, doi. 10.1038/jid.2015.121

By:

Hawkshaw, Nathan J;
Haslam, Iain S;
Ansell, David M;
Shamalak, Asim;
Paus, Ralf

Publication type:

Article

The Peripheral Clock Regulates Human Pigmentation.

Published in:

Journal of Investigative Dermatology, 2015, v. 135, n. 4, p. 1053, doi. 10.1038/jid.2014.442

By:

Hardman, Jonathan A;
Tobin, Desmond J;
Haslam, Iain S;
Farjo, Nilofer;
Farjo, Bessam;
Al-Nuaimi, Yusur;
Grimaldi, Benedetto;
Paus, Ralf

Publication type:

Article

The Ciliopathy Gene Rpgrip1l Is Essential for Hair Follicle Development.

Published in:

Journal of Investigative Dermatology, 2015, v. 135, n. 3, p. 701, doi. 10.1038/jid.2014.483

By:

Chen, Jiang;
Laclef, Christine;
Moncayo, Alejandra;
Snedecor, Elizabeth R;
Yang, Ning;
Li, Li;
Takemaru, Ken-Ichi;
Paus, Ralf;
Schneider-Maunoury, Sylvie;
Clark, Richard A

Publication type:

Article

Mitochondrial Function in Murine Skin Epithelium Is Crucial for Hair Follicle Morphogenesis and Epithelial-Mesenchymal Interactions.

Published in:

Journal of Investigative Dermatology, 2015, v. 135, n. 3, p. 679, doi. 10.1038/jid.2014.475

By:

Kloepper, Jennifer E;
Baris, Olivier R;
Reuter, Karen;
Kobayashi, Ken;
Weiland, Daniela;
Vidali, Silvia;
Tobin, Desmond J;
Niemann, Catherin;
Wiesner, Rudolf J;
Paus, Ralf

Publication type:

Article

Testing Chemotherapeutic Agents in the Feather Follicle Identifies a Selective Blockade of Cell Proliferation and a Key Role for Sonic Hedgehog Signaling in Chemotherapy-Induced Tissue Damage.

Published in:

Journal of Investigative Dermatology, 2015, v. 135, n. 3, p. 690, doi. 10.1038/jid.2014.409

By:

Xie, Guojiang;
Wang, Hangwei;
Yan, Zhipeng;
Cai, Linyan;
Zhou, Guixuan;
He, Wanzhong;
Paus, Ralf;
Yue, Zhicao

Publication type:

Article

A Synthetic Sandalwood Odorant Induces Wound-Healing Processes in Human Keratinocytes via the Olfactory Receptor OR2AT4.

Published in:

Journal of Investigative Dermatology, 2014, v. 134, n. 11, p. 2823, doi. 10.1038/jid.2014.273

By:

Busse, Daniela;
Kudella, Philipp;
Grüning, Nana-Maria;
Gisselmann, Günter;
Ständer, Sonja;
Luger, Thomas;
Jacobsen, Frank;
Steinsträßer, Lars;
Paus, Ralf;
Gkogkolou, Paraskevi;
Böhm, Markus;
Hatt, Hanns;
Benecke, Heike

Publication type:

Article

NF-κB Activity Is Required for Anagen Maintenance in Human Hair Follicles In Vitro.

Published in:

Journal of Investigative Dermatology, 2014, v. 134, n. 7, p. 2036, doi. 10.1038/jid.2014.82

By:

Kloepper, Jennifer E;
Ernst, Nancy;
Krieger, Karsten;
Bodó, Enikő;
Bíró, Tamás;
Haslam, Iain S;
Schmidt-Ullrich, Ruth;
Paus, Ralf

Publication type:

Article

Advanced Inhibition of Undesired Human Hair Growth by PPARγ Modulation?

Published in:

Journal of Investigative Dermatology, 2014, v. 134, n. 4, p. 1128, doi. 10.1038/jid.2013.473

By:

Ramot, Yuval;
Mastrofrancesco, Arianna;
Herczeg-Lisztes, Erika;
Bíró, Tamás;
Picardo, Mauro;
Kloepper, Jennifer E;
Paus, Ralf

Publication type:

Article

A Meeting of Two Chronobiological Systems: Circadian Proteins Period1 and BMAL1 Modulate the Human Hair Cycle Clock.

Published in:

Journal of Investigative Dermatology, 2014, v. 134, n. 3, p. 610, doi. 10.1038/jid.2013.366

By:

Al-Nuaimi, Yusur;
Hardman, Jonathan A;
Bíró, Tamás;
Haslam, Iain S;
Philpott, Michael P;
Tóth, Balázs I.;
Farjo, Nilofer;
Farjo, Bessam;
Baier, Gerold;
Watson, Rachel E B;
Grimaldi, Benedetto;
Kloepper, Jennifer E;
Paus, Ralf

Publication type:

Article

Hypothalamic-Pituitary-Thyroid Axis Hormones Stimulate Mitochondrial Function and Biogenesis in Human Hair Follicles.

Published in:

Journal of Investigative Dermatology, 2014, v. 134, n. 1, p. 33, doi. 10.1038/jid.2013.286

By:

Vidali, Silvia;
Knuever, Jana;
Lerchner, Johannes;
Giesen, Melanie;
Bíró, Tamás;
Klinger, Matthias;
Kofler, Barbara;
Funk, Wolfgang;
Poeggeler, Burkhard;
Paus, Ralf

Publication type:

Article

Blocking Potassium Channels (Kv1.3): A New Treatment Option for Alopecia Areata?

Published in:

Journal of Investigative Dermatology, 2013, v. 133, n. 8, p. 2088, doi. 10.1038/jid.2013.141

By:

Gilhar, Amos;
Keren, Aviad;
Shemer, Avner;
Ullmann, Yehuda;
Paus, Ralf

Publication type:

Article

Topobiology of Human Pigmentation: P-Cadherin Selectively Stimulates Hair Follicle Melanogenesis.

Published in:

Journal of Investigative Dermatology, 2013, v. 133, n. 6, p. 1591, doi. 10.1038/jid.2013.18

By:

Samuelov, Liat;
Sprecher, Eli;
Sugawara, Koji;
Singh, Suman K;
Tobin, Desmond J;
Tsuruta, Daisuke;
Bíró, Tamás;
Kloepper, Jennifer E;
Paus, Ralf

Publication type:

Article

Loss of γδ T Cells Results in Hair Cycling Defects.

Published in:

Journal of Investigative Dermatology, 2013, v. 133, n. 6, p. 1666, doi. 10.1038/jid.2013.17

By:

Kloepper, Jennifer E;
Kawai, Kazuhiro;
Bertolini, Marta;
Kanekura, Takuro;
Paus, Ralf

Publication type:

Article

Antimicrobial Peptides (AMPs) from Fish Epidermis: Perspectives for Investigative Dermatology.

Published in:

Journal of Investigative Dermatology, 2013, v. 133, n. 5, p. 1140, doi. 10.1038/jid.2012.503

By:

Rakers, Sebastian;
Niklasson, Lars;
Steinhagen, Dieter;
Kruse, Charli;
Schauber, Jürgen;
Sundell, Kristina;
Paus, Ralf

Publication type:

Article

Autoimmune Disease Induction in a Healthy Human Organ: A Humanized Mouse Model of Alopecia Areata.

Published in:

Journal of Investigative Dermatology, 2013, v. 133, n. 3, p. 844, doi. 10.1038/jid.2012.365

By:

Gilhar, Amos;
Keren, Aviad;
Shemer, Avner;
d'Ovidio, Roberto;
Ullmann, Yehuda;
Paus, Ralf

Publication type:

Article

P-Cadherin Regulates Human Hair Growth and Cycling via Canonical Wnt Signaling and Transforming Growth Factor-β2.

Published in:

Journal of Investigative Dermatology, 2012, v. 132, n. 10, p. 2332, doi. 10.1038/jid.2012.171

By:

Samuelov, Liat;
Sprecher, Eli;
Tsuruta, Daisuke;
Bíró, Tamás;
Kloepper, Jennifer E;
Paus, Ralf

Publication type:

Article