Works by Patrick T. Caswell

Results: 24

Combinatorial mathematical modelling approaches to interrogate rear retraction dynamics in 3D cell migration.

Published in:

PLoS Computational Biology, 2021, v. 17, n. 3, p. 1, doi. 10.1371/journal.pcbi.1008213

By:

Hetmanski, Joseph H. R.;
Jones, Matthew C.;
Chunara, Fatima;
Schwartz, Jean-Marc;
Caswell, Patrick T.

Publication type:

Article

Correction to: JIP3 localises to exocytic vesicles and focal adhesions in the growth cones of differentiated PC12 cells.

Published in:

2018

By:

Caswell, Patrick T.;
Dickens, Martin

Publication type:

Correction Notice

JIP3 localises to exocytic vesicles and focal adhesions in the growth cones of differentiated PC12 cells.

Published in:

Molecular & Cellular Biochemistry, 2018, v. 444, n. 1/2, p. 1, doi. 10.1007/s11010-017-3222-7

By:

Caswell, Patrick T.;
Dickens, Martin

Publication type:

Article

RCP-driven α5β1 recycling suppresses Rac and promotes RhoA activity via the RacGAP1-IQGAP1 complex.

Published in:

Journal of Cell Biology, 2013, v. 202, n. 6, p. 917, doi. 10.1083/jcb.201302041

By:

Jacquemet, Guillaume;
Green, David M.;
Bridgewater, Rebecca E.;
Von Kriegsheim, Alexander;
Humphries, Martin J.;
Norman, Jim C.;
Caswell, Patrick T.

Publication type:

Article

Diacylglycerol kinase α controls RCP-dependent integrin traficking to promote invasive migration.

Published in:

Journal of Cell Biology, 2012, v. 196, n. 2, p. 277, doi. 10.1083/jcb.201109112

By:

Rainero, Elena;
Caswell, Patrick T.;
Muller, Patricia A. J.;
Grindlay, Joan;
McCaffrey, Mary W.;
Zhang, Qifeng;
Wakelam, Michael J. O.;
Vousden, Karen H.;
Graziani, Andrea;
Norman, Jim C.

Publication type:

Article

Rab-coupling protein coordinates recycling of α5β1 integrin and EGFR1 to promote cell migration in 3D microenvironments.

Published in:

Journal of Cell Biology, 2008, v. 183, n. 1, p. 143, doi. 10.1083/jcb.200804140

By:

Caswell, Patrick T.;
Chan, May;
Lindsay, Andrew J.;
McCaffrey, Mary W.;
Boettiger, David;
Norman, Jim C.

Publication type:

Article

αvβ3 and α5β1 integrin recycling pathways dictate downstream Rho kinase signaling to regulate persistent cell migration.

Published in:

Journal of Cell Biology, 2007, v. 177, n. 3, p. 515, doi. 10.1083/jcb.200609004

By:

White, Dominic P.;
Caswell, Patrick T.;
Norman, Jim C.

Publication type:

Article

Endocytic recycling is central to circadian collagen fibrillogenesis and disrupted in fibrosis.

Published in:

eLife, 2025, p. 1, doi. 10.7554/eLife.95842

By:

Joan Chang;
Pickard, Adam;
Herrera, Jeremy A.;
O'Keefe, Sarah;
Garva, Richa;
Hartshorn, Matthew;
Hoyle, Anna;
Dingle, Lewis;
Knox, John;
Jowitt, Thomas A.;
Coy, Madeleine;
Wong, Jason;
Reid, Adam;
Yinhui Lu;
Zeltz, Cédric;
Venkateswaran, Rajamiyer V.;
Caswell, Patrick T.;
High, Stephen;
Gullberg, Donald;
Kadler, Karl E.

Publication type:

Article

Neuropilin-1/GIPC1 Signaling Regulates 51 Integrin Traffic and Function in Endothelial Cells.

Published in:

PLoS Biology, 2009, v. 7, n. 1, p. e1000025, doi. 10.1371/journal.pbio.1000025

By:

Valdembri, Donatella;
Caswell, Patrick T.;
Anderson, Kurt I.;
Schwarz, Juliane P.;
König, Ireen;
Astanina, Elena;
Caccavari, Francesca;
Norman, Jim C.;
Humphries, Martin J.;
Bussolino, Federico;
Serini, Guido

Publication type:

Article

A combinatorial culture strategy to develop pseudomyxoma peritonei organoid models.

Published in:

Journal of Surgical Oncology, 2024, v. 130, n. 6, p. 1213, doi. 10.1002/jso.27850

By:

Varinelli, Luca;
Di Bella, Marzia;
Guaglio, Marcello;
Battistessa, Davide;
Pisati, Federica;
Cavalleri, Tommaso;
Milione, Massimo;
Martínez‐Quintanilla, Jordi;
Caswell, Patrick T.;
Baratti, Dario;
Kusamura, Shigeki;
Deraco, Marcello;
Gariboldi, Manuela

Publication type:

Article

Rationalizing Rac1 and RhoA GTPase signaling: A mathematical approach.

Published in:

Small GTPases, 2018, v. 9, n. 3, p. 224, doi. 10.1080/21541248.2016.1218406

By:

Hetmanski, Joseph H. R.;
Schwartz, Jean-Marc;
Caswell, Patrick T.

Publication type:

Article

PKD1/PKCµ promotes avß3 integrin recycling and delivery to nascent focal adhesions.

Published in:

EMBO Journal, 2004, v. 23, n. 13, p. 2531, doi. 10.1038/sj.emboj.7600267

By:

Woods, Alison J.;
White, Dominic P.;
Caswell, Patrick T.;
Norman, Jim C.

Publication type:

Article

A MAPK-Driven Feedback Loop Suppresses Rac Activity to Promote RhoA-Driven Cancer Cell Invasion.

Published in:

PLoS Computational Biology, 2016, v. 12, n. 5, p. 1, doi. 10.1371/journal.pcbi.1004909

By:

Hetmanski, Joseph H. R.;
Zindy, Egor;
Schwartz, Jean-Marc;
Caswell, Patrick T.

Publication type:

Article

ARF3 weights the balance for prostate cancer metastasis.

Published in:

Journal of Cell Biology, 2023, v. 222, n. 4, p. 1, doi. 10.1083/jcb.202303037

By:

Caswell, Patrick T.

Publication type:

Article

α5β1 integrin recycling promotes Arp2/3-independent cancer cell invasion via the formin FHOD3.

Published in:

Journal of Cell Biology, 2015, v. 210, n. 6, p. 1013, doi. 10.1083/jcb.201502040

By:

Paul, Nikki R.;
Allen, Jennifer L.;
Chapman, Anna;
Morlan-Mairal, Maria;
Zindy, Egor;
Jacquemet, Guillaume;
Fernandez del Ama, Laura;
Ferizovic, Nermina;
Green, David M.;
Howe, Jonathan D.;
Ehler, Elisabeth;
Hurlstone, Adam;
Caswell, Patrick T.

Publication type:

Article

Vesicle trafficking pathways that direct cell migration in 3D matrices and in vivo.

Published in:

Traffic, 2018, v. 19, n. 12, p. 899, doi. 10.1111/tra.12605

By:

Wilson, Beverley J.;
Allen, Jennifer L.;
Caswell, Patrick T.

Publication type:

Article

VEGFR1 (Flt1) Regulates Rab4 Recycling to Control Fibronectin Polymerization and Endothelial Vessel Branching.

Published in:

Traffic, 2009, v. 10, n. 6, p. 754, doi. 10.1111/j.1600-0854.2009.00898.x

By:

Jones, Matthew C.;
Caswell, Patrick T.;
Moran-Jones, Kim;
Roberts, Marnie;
Barry, Simon T.;
Gampel, Alexandra;
Mellor, Harry;
Norman, Jim C.

Publication type:

Article

On demand expression control of endogenous genes with DExCon, DExogron and LUXon reveals differential dynamics of Rab11 family members.

Published in:

eLife, 2022, p. 1, doi. 10.7554/eLife.76651

By:

Gemperle, Jakub;
Harrison, Thomas S.;
Flett, Chloe;
Adamson, Antony D.;
Caswell, Patrick T.

Publication type:

Article

Phosphorylation of Rab-coupling protein by LMTK3 controls Rab14-dependent EphA2 trafficking to promote cell:cell repulsion.

Published in:

Nature Communications, 2017, v. 8, n. 3, p. 14646, doi. 10.1038/ncomms14646

By:

Gundry, Christine;
Marco, Sergi;
Rainero, Elena;
Miller, Bryan;
Dornier, Emmanuel;
Mitchell, Louise;
Caswell, Patrick T.;
Campbell, Andrew D.;
Hogeweg, Anna;
Sansom, Owen J.;
Morton, Jennifer P.;
Norman, Jim C.

Publication type:

Article

Integrins: masters and slaves of endocytic transport.

Published in:

Nature Reviews Molecular Cell Biology, 2009, v. 10, n. 12, p. 843, doi. 10.1038/nrm2799

By:

Caswell, Patrick T.;
Vadrevu, Suryakiran;
Norman, Jim C.

Publication type:

Article

Integrin Trafficking and the Control of Cell Migration.

Published in:

Traffic, 2006, v. 7, n. 1, p. 14, doi. 10.1111/j.1600-0854.2005.00362.x

By:

Caswell, Patrick T.;
Norman, Jim C.

Publication type:

Article

Epigenetic inactivation of protein kinase D1 in gastric cancer and its role in gastric cancer cell migration and invasion.

Published in:

Carcinogenesis, 2008, v. 29, n. 3, p. 629

By:

Mirang Kim;
Hay-Ran Jang;
Jeong-Hwan Kim;
Seung-Moo Noh;
Kyu-Sang Song;
June-Sik Cho;
Hyun-Yong Jeong;
Jim C. Norman;
Patrick T. Caswell;
Gyeong Hoon Kang;
Seon-Young Kim;
Hyang-Sook Yoo;
Yong Sung Kim

Publication type:

Article

Modelling GTPase dynamics to understand RhoA-driven cancer cell invasion.

Published in:

Biochemical Society Transactions, 2016, v. 44, n. 6, p. 1695, doi. 10.1042/BST20160184

By:

Hetmanski, Joseph H.R.;
Schwartz, Jean-Marc;
Caswell, Patrick T.

Publication type:

Article

Rab11 and Its Effector Rab Coupling Protein Contribute to the Trafficking of β1 Integrins during Axon Growth in Adult Dorsal Root Ganglion Neurons and PC12 Cells.

Published in:

Journal of Neuroscience, 2010, v. 30, n. 35, p. 11654, doi. 10.1523/JNEUROSCI.2425-10.2010

By:

Eva, Richard;
Dassie, Elisa;
Caswell, Patrick T.;
Dick, Gunnar;
Ffrench-Constant, Charles;
Norman, Jim C.;
Fawcett, James W.

Publication type:

Article