Works matching AU Pathak, Medha M.

Results: 11

Visualizing PIEZO1 localization and activity in hiPSC-derived single cells and organoids with HaloTag technology.

Published in:

Nature Communications, 2025, v. 16, n. 1, p. 1, doi. 10.1038/s41467-025-59150-1

By:

Bertaccini, Gabriella A.;
Casanellas, Ignasi;
Evans, Elizabeth L.;
Nourse, Jamison L.;
Dickinson, George D.;
Liu, Gaoxiang;
Seal, Sayan;
Ly, Alan T.;
Holt, Jesse R.;
Wijerathne, Tharaka D.;
Yan, Shijun;
Hui, Elliot E.;
Lacroix, Jerome J.;
Panicker, Mitradas M.;
Upadhyayula, Srigokul;
Parker, Ian;
Pathak, Medha M.

Publication type:

Article

The twisted ion-permeation pathway of a resting voltage-sensing domain.

Published in:

Nature, 2007, v. 445, n. 7127, p. 546, doi. 10.1038/nature05396

By:

Tombola, Francesco;
Pathak, Medha M.;
Gorostiza, Pau;
Isacoff, Ehud Y.

Publication type:

Article

Mechanically activated ion channel Piezo1 modulates macrophage polarization and stiffness sensing.

Published in:

Nature Communications, 2021, v. 12, n. 1, p. 1, doi. 10.1038/s41467-021-23482-5

By:

Atcha, Hamza;
Jairaman, Amit;
Holt, Jesse R.;
Meli, Vijaykumar S.;
Nagalla, Raji R.;
Veerasubramanian, Praveen Krishna;
Brumm, Kyle T.;
Lim, Huy E.;
Othy, Shivashankar;
Cahalan, Michael D.;
Pathak, Medha M.;
Liu, Wendy F.

Publication type:

Article

Myosin-II mediated traction forces evoke localized Piezo1-dependent Ca<sup>2+</sup> flickers.

Published in:

Communications Biology, 2019, v. 2, n. 1, p. N.PAG, doi. 10.1038/s42003-019-0514-3

By:

Ellefsen, Kyle L.;
Holt, Jesse R.;
Chang, Alice C.;
Nourse, Jamison L.;
Arulmoli, Janahan;
Mekhdjian, Armen H.;
Abuwarda, Hamid;
Tombola, Francesco;
Flanagan, Lisa A.;
Dunn, Alexander R.;
Parker, Ian;
Pathak, Medha M.

Publication type:

Article

Spatiotemporal dynamics of PIEZO1 localization controls keratinocyte migration during wound healing.

Published in:

eLife, 2021, p. 1, doi. 10.7554/eLife.65415

By:

Holt, Jesse R.;
Wei-Zheng Zeng;
Evans, Elizabeth L.;
Seung-Hyun Woo;
Shang Ma;
Abuwarda, Hamid;
Loud, Meaghan;
Patapoutian, Ardem;
Pathak, Medha M.

Publication type:

Article

Membrane curvature governs the distribution of Piezo1 in live cells.

Published in:

Nature Communications, 2022, v. 13, n. 1, p. 1, doi. 10.1038/s41467-022-35034-6

By:

Yang, Shilong;
Miao, Xinwen;
Arnold, Steven;
Li, Boxuan;
Ly, Alan T.;
Wang, Huan;
Wang, Matthew;
Guo, Xiangfu;
Pathak, Medha M.;
Zhao, Wenting;
Cox, Charles D.;
Shi, Zheng

Publication type:

Article

Crosstalk Between CD11b and Piezo1 Mediates Macrophage Responses to Mechanical Cues.

Published in:

Frontiers in Immunology, 2021, v. 12, p. 1, doi. 10.3389/fimmu.2021.689397

By:

Atcha, Hamza;
Meli, Vijaykumar S.;
Davis, Chase T.;
Brumm, Kyle T.;
Anis, Sara;
Chin, Jessica;
Jiang, Kevin;
Pathak, Medha M.;
Liu, Wendy F.

Publication type:

Article

Mechanosensitive Ion Channel Piezo1 Regulates Diet-Induced Adipose Inflammation and Systemic Insulin Resistance.

Published in:

Frontiers in Endocrinology, 2019, p. N.PAG, doi. 10.3389/fendo.2019.00373

By:

Zhao, Can;
Sun, Qiushi;
Tang, Lingyi;
Cao, Yang;
Nourse, Jamison L.;
Pathak, Medha M.;
Lu, Xiang;
Yang, Qin

Publication type:

Article

Evidence for Functional Diversity between the Voltage-Gated Proton Channel Hv1 and Its Closest Related Protein HVRP1.

Published in:

PLoS ONE, 2014, v. 9, n. 8, p. 1, doi. 10.1371/journal.pone.0105926

By:

Kim, Iris H.;
Hevezi, Peter;
Varga, Csaba;
Pathak, Medha M.;
Hong, Liang;
Ta, Dennis;
Tran, Chau T.;
Zlotnik, Albert;
Soltesz, Ivan;
Tombola, Francesco

Publication type:

Article

Static stretch affects neural stem cell differentiation in an extracellular matrix-dependent manner.

Published in:

Scientific Reports, 2015, p. 8499, doi. 10.1038/srep08499

By:

Arulmoli, Janahan;
Pathak, Medha M.;
Tombola, Francesco;
McDonnell, Lisa P.;
Nourse, Jamison L.;
Earthman, James C.;
Flanagan, Lisa A.

Publication type:

Article

PIEZO1 regulates leader cell formation and cellular coordination during collective keratinocyte migration.

Published in:

PLoS Computational Biology, 2024, v. 20, n. 4, p. 1, doi. 10.1371/journal.pcbi.1011855

By:

Chen, Jinghao;
Holt, Jesse R.;
Evans, Elizabeth L.;
Lowengrub, John S.;
Pathak, Medha M.

Publication type:

Article