Found: 8

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  • Inhibiting EZH2 targets atypical teratoid rhabdoid tumor by triggering viral mimicry via both RNA and DNA sensing pathways.

    Published in:
    Nature Communications, 2024, v. 15, n. 1, p. 1, doi. 10.1038/s41467-024-53515-8
    By:
    • Feng, Shengrui;
    • Marhon, Sajid A.;
    • Sokolowski, Dustin J.;
    • D'Costa, Alister;
    • Soares, Fraser;
    • Mehdipour, Parinaz;
    • Ishak, Charles;
    • Loo Yau, Helen;
    • Ettayebi, Ilias;
    • Patel, Parasvi S.;
    • Chen, Raymond;
    • Liu, Jiming;
    • Zuzarte, Philip C.;
    • Ho, King Ching;
    • Ho, Ben;
    • Ning, Shiyao;
    • Huang, Annie;
    • Arrowsmith, Cheryl H.;
    • Wilson, Michael D.;
    • Simpson, Jared T.
    Publication type:
    Article

  • The RNA m5C modification in R-loops as an off switch of Alt-NHEJ.

    Published in:
    Nature Communications, 2023, v. 14, n. 1, p. 1, doi. 10.1038/s41467-023-41790-w
    By:
    • Yang, Haibo;
    • Lachtara, Emily M.;
    • Ran, Xiaojuan;
    • Hopkins, Jessica;
    • Patel, Parasvi S.;
    • Zhu, Xueping;
    • Xiao, Yao;
    • Phoon, Laiyee;
    • Gao, Boya;
    • Zou, Lee;
    • Lawrence, Michael S.;
    • Lan, Li
    Publication type:
    Article

  • BRCA1 and Metastasis: Outcome of Defective DNA Repair.

    Published in:
    Cancers, 2022, v. 14, n. 1, p. 108, doi. 10.3390/cancers14010108
    By:
    • Krishnan, Rehna;
    • Patel, Parasvi S.;
    • Hakem, Razqallah
    Publication type:
    Article

  • Ubiquitin ligase RNF8 suppresses Notch signaling to regulate mammary development and tumorigenesis.

    Published in:
    2021
    By:
    • Li, Li;
    • Guturi, Kiran Kumar Naidu;
    • Gautreau, Brandon;
    • Patel, Parasvi S;
    • Saad, Amine;
    • Morii, Mayako;
    • Mateo, Francesca;
    • Palomero, Luis;
    • Barbour, Haithem;
    • Gomez, Antonio;
    • Ng, Deborah;
    • Kotlyar, Max;
    • Pastrello, Chiara;
    • Jackson, Hartland W;
    • Khokha, Rama;
    • Jurisica, Igor;
    • Affar, El Bachir;
    • Raught, Brian;
    • Sanchez, Otto;
    • Alaoui-Jamali, Moulay
    Publication type:
    journal article

  • RNF168 regulates R-loop resolution and genomic stability in BRCA1/2-deficient tumors.

    Published in:
    2021
    By:
    • Patel, Parasvi S.;
    • Abraham, Karan Joshua;
    • Naidu Guturi, Kiran Kumar;
    • Halaby, Marie-Jo;
    • Khan, Zahra;
    • Palomero, Luis;
    • Ho, Brandon;
    • Duan, Shili;
    • St-Germain, Jonathan;
    • Algouneh, Arash;
    • Mateo, Francesca;
    • El Ghamrasni, Samah;
    • Barbour, Haithem;
    • Barnes, Daniel R.;
    • Beesley, Jonathan;
    • Sanchez, Otto;
    • Berman, Hal K.;
    • Brown, Grant W.;
    • Affar, El Bachir;
    • Chenevix-Trench, Georgia
    Publication type:
    journal article

  • Ubiquitin ligase RNF8 suppresses Notch signaling to regulate mammary development and tumorigenesis.

    Published in:
    2018
    By:
    • Li Li;
    • Naidu Guturi, Kiran Kumar;
    • Gautreau, Brandon;
    • Patel, Parasvi S.;
    • Saad, Amine;
    • Morii, Mayako;
    • Mateo, Francesca;
    • Palomero, Luis;
    • Barbour, Haithem;
    • Gomez, Antonio;
    • Deborah Ng;
    • Kotlyar, Max;
    • Pastrello, Chiara;
    • Jackson, Hartland W.;
    • Khokha, Rama;
    • Jurisica, Igor;
    • Affar, El Bachir;
    • Raught, Brian;
    • Sanchez, Otto;
    • Alaoui-Jamali, Moulay
    Publication type:
    journal article

  • RNF8 ubiquitylation of XRN2 facilitates R-loop resolution and restrains genomic instability in BRCA1 mutant cells.

    Published in:
    Nucleic Acids Research, 2023, v. 51, n. 19, p. 10484, doi. 10.1093/nar/gkad733
    By:
    • Krishnan, Rehna;
    • Lapierre, Mariah;
    • Gautreau, Brandon;
    • Nixon, Kevin C J;
    • El Ghamrasni, Samah;
    • Patel, Parasvi S;
    • Hao, Jun;
    • Yerlici, V Talya;
    • Guturi, Kiran Kumar Naidu;
    • St-Germain, Jonathan;
    • Mateo, Francesca;
    • Saad, Amine;
    • Algouneh, Arash;
    • Earnshaw, Rebecca;
    • Shili, Duan;
    • Seitova, Alma;
    • Miller, Joshua;
    • Khosraviani, Negin;
    • Penn, Adam;
    • Ho, Brandon
    Publication type:
    Article

  • Excessive transcription-replication conflicts are a vulnerability of BRCA1-mutant cancers.

    Published in:
    Nucleic Acids Research, 2023, v. 51, n. 9, p. 4341, doi. 10.1093/nar/gkad172
    By:
    • Patel, Parasvi S;
    • Algouneh, Arash;
    • Krishnan, Rehna;
    • Reynolds, John J;
    • Nixon, Kevin C J;
    • Hao, Jun;
    • Lee, Jihoon;
    • Feng, Yue;
    • Fozil, Chehronai;
    • Stanic, Mia;
    • Yerlici, Talya;
    • Su, Peiran;
    • Soares, Fraser;
    • Liedtke, Elisabeth;
    • Prive, Gil;
    • Baider, Gary D;
    • Pujana, Miquel Angel;
    • Mekhail, Karim;
    • He, Housheng Hansen;
    • Hakem, Anne
    Publication type:
    Article