Works by Patat, Alain

Results: 38

A Study of the Potential Interaction Between Bazedoxifene and Atorvastatin in Healthy Postmenopausal Women.

Published in:

Clinical Pharmacology in Drug Development, 2018, v. 7, n. 8, p. 911, doi. 10.1002/cpdd.458

By:

McKeand, William;
Baird‐Bellaire, Susan;
Ermer, James;
Patat, Alain

Publication type:

Article

Pharmacokinetics and Safety of Bazedoxifene in Hepatically Impaired and Healthy Postmenopausal Women.

Published in:

Clinical Pharmacology in Drug Development, 2018, v. 7, n. 4, p. 365, doi. 10.1002/cpdd.438

By:

McKeand, William;
Baird‐Bellaire, Susan;
Ermer, James;
Patat, Alain

Publication type:

Article

Pharmacokinetic Drug Interaction Study of Bazedoxifene and Ibuprofen.

Published in:

Clinical Pharmacology in Drug Development, 2018, v. 7, n. 4, p. 358, doi. 10.1002/cpdd.433

By:

McKeand, William;
Baird‐Bellaire, Susan;
Ermer, James;
Patat, Alain

Publication type:

Article

Evaluation of opicapone on cardiac repolarization in a thorough QT/QTc study.

Published in:

Clinical Pharmacology in Drug Development, 2015, v. 4, n. 6, p. 454, doi. 10.1002/cpdd.188

By:

Pinto, Roberto;
l'Hostis, Philippe;
Patat, Alain;
Homery, Marie‐Claude;
Falcão, Amílcar;
Nunes, Teresa;
Rocha, José‐Francisco;
Soares‐da‐Silva, Patrício

Publication type:

Article

Pharmacodynamic profile of Zaleplon, a new non-benzodiazepine hypnotic agent.

Published in:

Human Psychopharmacology: Clinical & Experimental, 2001, v. 16, n. 5, p. 369, doi. 10.1002/hup.310

By:

Patat, Alain;
Paty, Isabelle;
Hindmarch, Ian

Publication type:

Article

Residual effects of zaleplon and zolpidem following middle of the night administration five hours to one hour before awakening.

Published in:

Human Psychopharmacology: Clinical & Experimental, 2001, v. 16, n. 2, p. 159, doi. 10.1002/hup.282

By:

Hindmarch, Ian;
Patat, Alain;
Stanley, Neil;
Paty, Isabelle;
Rigney, Una

Publication type:

Article

Clinical pharmacology of psychotropic drugs.

Published in:

Human Psychopharmacology: Clinical & Experimental, 2000, v. 15, n. 5, p. 361, doi. 10.1002/1099-1077(200007)15:5<361::AID-HUP205>3.0.CO;2-1

By:

Patat, Alain

Publication type:

Article

Effects of a new slow release formulation of caffeine on EEG, psychomotor and cognitive functions in sleep-deprived subjects.

Published in:

Human Psychopharmacology: Clinical & Experimental, 2000, v. 15, n. 3, p. 153, doi. 10.1002/(SICI)1099-1077(200004)15:3<153::AID-HUP154>3.0.CO;2-C

By:

Patat, Alain;
Rosenzweig, Pierre;
Enslen, Marc;
Trocherie, Suzanne;
Miget, Nathalie;
Bozon, Marie-Christine;
Allain, Hervé;
Gandon, Jean-Marc

Publication type:

Article

EEG, MAO-A inhibition, pharmacokinetics and safety of befloxatone in the elderly.

Published in:

Human Psychopharmacology: Clinical & Experimental, 1997, v. 12, n. 6, p. 557, doi. 10.1002/(SICI)1099-1077(199711/12)12:6<557::AID-HUP923>3.0.CO;2-P

By:

Patat, Alain;
Dubruc, Catherine;
Deschamp, Claire;
Durrieu, Geneviève;
Trocherie, Suzanne;
Cimarosti, Isabelle;
Allain, Hervé;
Rosenzweig, Pierre;
Gandon, Jean-Marc

Publication type:

Article

Lack of Amphetamine-Like Effects After Administration of Mefenorex in Normal Young Subjects.

Published in:

Human Psychopharmacology: Clinical & Experimental, 1996, v. 11, n. 4, p. 321, doi. 10.1002/(SICI)1099-1077(199607)11:4<321::AID-HUP803>3.0.CO;2-6

By:

Patat, Alain;
Cercle, Micakäel;
Trocherie, Suzanne;
Peytavin, Guylaine;
Potin, Christophe;
Allain, Hervé;
Gandon, Jean-Marc

Publication type:

Article

Effect of Drugs on Mnestic Performance: A Methodological Approach.

Published in:

Human Psychopharmacology: Clinical & Experimental, 1996, v. 11, n. 1, p. 11, doi. 10.1002/(SICI)1099-1077(199601)11:1<11::AID-HUP734>3.0.CO;2-K

By:

Allain, Hervé;
Lieury, Alain;
Belliard, Serge;
Caldwell, Maeve;
Patat, Alain;
Gandon, Jean-Marc

Publication type:

Article

The evaluation of potential pharmacokinetic interaction between sirolimus and tacrolimus in healthy volunteers.

Published in:

European Journal of Clinical Pharmacology, 2013, v. 69, n. 4, p. 835, doi. 10.1007/s00228-012-1407-2

By:

Tortorici, Michael;
Parks, Virginia;
Matschke, Kyle;
Korth-Bradley, Joan;
Patat, Alain

Publication type:

Article

Electroretinography and contrast sensitivity, complementary translational biomarkers of sensory deficits in the visual system of individuals with fragile X syndrome.

Published in:

Journal of Neurodevelopmental Disorders, 2021, v. 13, n. 1, p. 1, doi. 10.1186/s11689-021-09375-0

By:

Perche, Olivier;
Lesne, Fabien;
Patat, Alain;
Raab, Susanne;
Twyman, Roy;
Ring, Robert H.;
Briault, Sylvain

Publication type:

Article

A single-dose PK study of onapristone including the effect of food on absorption.

Published in:

Cancer Chemotherapy & Pharmacology, 2015, v. 76, n. 1, p. 171, doi. 10.1007/s00280-015-2754-3

By:

Rezai, Keyvan;
Chassard, Didier;
Denot, Caroline;
Proniuk, Stefan;
Zukiwski, Alexander;
Gilles, Erard;
Ramos, Haydeé;
Patat, Alain;
Bexon, Alice;
Lokiec, François

Publication type:

Article

Pharmacokinetics, safety, and tolerability of the 2‐ and 3‐direct‐acting antiviral combination of AL‐335, odalasvir, and simeprevir in healthy subjects.

Published in:

Pharmacology Research & Perspectives, 2018, v. 6, n. 3, p. 1, doi. 10.1002/prp2.395

By:

Kakuda, Thomas N.;
McClure, Matthew W.;
Westland, Christopher;
Vuong, Jennifer;
Homery, Marie‐Claude;
Poizat, Gwendoline;
Viguerie, Laure;
Denot, Caroline;
Patat, Alain;
Zhang, Qingling;
Hui, James;
Apelian, David;
Smith, David B.;
Chanda, Sushmita M.;
Fry, John

Publication type:

Article

Pharmacodynamic interactions of a solid formulation of sodium oxybate and ethanol in healthy volunteers.

Published in:

British Journal of Clinical Pharmacology, 2015, v. 80, n. 3, p. 480, doi. 10.1111/bcp.12632

By:

Pross, Nathalie;
Patat, Alain;
Vivet, Philippe;
Bidaut, Michelle;
Fauchoux, Nicolas

Publication type:

Article

Effects of 50mg amisulpride on EEG, psychomotor and cognitive functions in healthy sleep-deprived subjects.

Published in:

Fundamental & Clinical Pharmacology, 1999, v. 13, n. 5, p. 582, doi. 10.1111/j.1472-8206.1999.tb00365.x

By:

Patat, Alain;
Rosenzweig, Pierre;
Miget, Nathalie;
Allain, Hervé;
Gandon, Jean-Marc

Publication type:

Article

Effects of the glycine reuptake inhibitors bitopertin and RG7118 on glycine in cerebrospinal fluid: results of two proofs of mechanism studies in healthy volunteers.

Published in:

Psychopharmacology, 2016, v. 233, n. 13, p. 2429, doi. 10.1007/s00213-016-4317-7

By:

Hofmann, Carsten;
Pizzagalli, Flavia;
Boetsch, Christophe;
Alberati, Daniela;
Ereshefsky, Larry;
Jhee, Stanford;
Patat, Alain;
Boutouyrie-Dumont, Bruno;
Martin-Facklam, Meret

Publication type:

Article

Large-conductance calcium-activated potassium channel haploinsufficiency leads to sensory deficits in the visual system: a case report.

Published in:

2022

By:

Perche, Olivier;
Lesne, Fabien;
Patat, Alain;
Raab, Susanne;
Twyman, Roy;
Ring, Robert H.;
Briault, Sylvain

Publication type:

journal article

Safety, tolerability, and pharmacokinetics of AL-335 in healthy volunteers and hepatitis C virus-infected subjects.

Published in:

PLoS ONE, 2018, v. 13, n. 10, p. 1, doi. 10.1371/journal.pone.0204974

By:

McClure, Matthew W.;
Berliba, Elina;
Tsertsvadze, Tengiz;
Streinu-Cercel, Adrian;
Vijgen, Leen;
Astruc, Béatrice;
Patat, Alain;
Westland, Christopher;
Chanda, Sushmita;
Zhang, Qingling;
Kakuda, Thomas N.;
Vuong, Jennifer;
Khorlin, Nick;
Beigelman, Leonid;
Blatt, Lawrence M.;
Fry, John

Publication type:

Article

A safety grading scale to support dose escalation and define stopping rules for healthy subject first-entry-into-man studies.

Published in:

British Journal of Clinical Pharmacology, 2010, v. 70, n. 5, p. 736, doi. 10.1111/j.1365-2125.2010.03741.x

By:

Sibille, Michel;
Patat, Alain;
Caplain, Henri;
Donazzolo, Yves

Publication type:

Article

Safety, tolerability, pharmacokinetics and pharmacodynamics of ascending single and multiple doses of lecozotan in healthy young and elderly subjects.

Published in:

British Journal of Clinical Pharmacology, 2009, v. 67, n. 3, p. 299, doi. 10.1111/j.1365-2125.2008.03348.x

By:

Patat, Alain;
Parks, Virginia;
Raje, Sangeeta;
Plotka, Anna;
Chassard, Didier;
Coz, F. Le

Publication type:

Article

Lack of pharmacokinetic interaction between retigabine and phenobarbitone at steady-state in healthy subjects.

Published in:

British Journal of Clinical Pharmacology, 2003, v. 56, n. 1, p. 39, doi. 10.1046/j.1365-2125.2003.01825.x

By:

Ferron, Geraldine M.;
Patat, Alain;
Parks, Virginia;
Rolan, Paul;
Troy, Steven M.

Publication type:

Article

Noise-induced sleep maintenance insomnia: hypnotic and residual effects of zaleplon.

Published in:

British Journal of Clinical Pharmacology, 2002, v. 53, n. 2, p. 196, doi. 10.1046/j.-5251.2001.01520.x

By:

Stone, Barbara M;
Turner, Claire;
Mills, Sue L;
Paty, Isabelle;
Patat, Alain;
Darwish, Mona;
Danjou, Philippe

Publication type:

Article

Effect of Multiple Oral Doses of the Potent CYP3A4 Inhibitor Clarithromycin on the Pharmacokinetics of a Single Oral Dose of Vonoprazan: A Phase I, Open-Label, Sequential Design Study.

Published in:

Clinical Drug Investigation, 2017, v. 37, n. 3, p. 311, doi. 10.1007/s40261-016-0488-6

By:

Jenkins, Helen;
Jenkins, Richard;
Patat, Alain

Publication type:

Article

Absence of a Clinically Relevant Interaction Between Etanercept and Digoxin.

Published in:

Journal of Clinical Pharmacology, 2004, v. 44, n. 11, p. 1244, doi. 10.1177/0091270004268050

By:

Zhou, Honghui;
Parks, Virginia;
Patat, Alain;
Le Coz, Franck;
Simcoe, Donna;
Korth-Bradley, Joan

Publication type:

Article

Absence of a Pharmacokinetic Interaction between Etanercept and Warfarin.

Published in:

Journal of Clinical Pharmacology, 2004, v. 44, n. 5, p. 543

By:

Honghui Zhou;
Alain Patat;
Virginia Parks;
Mary Buckwalter;
Deborah Metzger;
Joan Korth-Bradley

Publication type:

Article

Absolute Bioavailability and Electroencephalographic Effects of Conventional and Extended-Release Formulations of Venlafaxine in Healthy Subjects.

Published in:

1998

By:

Patat, Alain;
Troy, Steven;
Burke, Jim;
Trocherie, Suzanne;
Danjou, Philippe;
Coz, Franck Le;
Allain, Hervé;
Gandon, Jean-Marc

Publication type:

Other

Effects of Befloxatone, a Reversible Selective Monoamine Oxidase-A Inhibitor, on Psychomotor Function and Memory in Healthy Subjects.

Published in:

1996

By:

Warot, Dominique;
Berlin, Ivan;
Patat, Alain;
Durrieu, Geneviève;
Zieleniuk, Isabelle;
Puech, Alain J.

Publication type:

Other

Pharmacodynamics and Pharmacokinetics of Two Dose Regimens of Befloxatone, a New Reversible and Selective Monoamine Oxidase Inhibitor, at Steady State in Healthy Volunteers.

Published in:

1996

By:

Patat, Alain;
Coz, Franck;
Dubruc, Catherine;
Gandon, Jean-Marc;
Durrieu, Geneviève;
Cimarosti, Isabelle;
Jezequel, Sylvie;
Curet, Olivier;
Zieleniuk, Isabelle;
Allain, Hervé;
Rosenzweig, Pierre

Publication type:

Other

Pressor Effect of Oral Tyramine During Treatment with Befloxatone, a New Reversible Monoamine Oxidase-A Inhibitor, in Healthy Subjects.

Published in:

1995

By:

Patat, Alain;
Berlin, Ivan;
Durrieu, Geneviève;
Armand, Pierre;
Fitoussi, Serge;
Molinier, Patricia;
Caille, Philippe

Publication type:

Other

Cognitive performance in elderly subjects after a single dose of befloxatone, a new reversible selective monoamine oxidase A inhibitor<sup>*</sup>.

Published in:

Clinical Pharmacology & Therapeutics, 1998, v. 64, n. 2, p. 211, doi. 10.1016/S0009-9236(98)90155-2

By:

Rosenzweig, Pierre;
Patat, Alain;
Zieleniuk, Isabelle;
Cimarosti, Isabelle;
Allain, Hervé;
Gandon, Jean-Marc

Publication type:

Article

Postural Instability and Consequent Falls and Hip Fractures Associated with Use of Hypnotics in the Elderly.

Published in:

Drugs & Aging, 2005, v. 22, n. 9, p. 749, doi. 10.2165/00002512-200522090-00004

By:

Allain, Hervé;
Bentué-Ferrer, Danièle;
Polard, Elisabeth;
Akwa, Yvette;
Patat, Alain

Publication type:

Article

Safety, Pharmacokinetic, and Pharmacodynamic Evaluations of PI-2301, a Potent Immunomodulator, in a First-in-Human, Single-Ascending-Dose Study in Healthy Volunteers.

Published in:

Journal of Clinical Pharmacology, 2011, v. 51, n. 5, p. 649, doi. 10.1177/0091270010373930

By:

Kovalchin, Joseph;
Krieger, Jeffrey;
Collins, Kathy;
Genova, Michelle;
Augustyniak, Michael;
Masci, Allyson;
Avril, Tony;
Gandon, Gwenola;
Patat, Alain;
Fauchoux, Nicolas;
Toutin, Claire;
Lacoste, Eric;
Patel, Uday;
Mascioli, Edward;
Zanelli, Eric

Publication type:

Article

Pharmacokinetics and Safety of a Single Intravenous Dose of the Antibiotic Tigecycline in Patients With Cirrhosis.

Published in:

Journal of Clinical Pharmacology, 2011, v. 51, n. 1, p. 93, doi. 10.1177/0091270010363477

By:

Korth-Bradley, Joan M.;
Baird-Bellaire, Susan J.;
Patat, Alain A.;
Troy, Steven M.;
Böhmer, Gabriele M.;
Gleiter, Christoph H.;
Buecheler, Reinhild;
Morgan, Marsha Y.

Publication type:

Article

Antiviral activity of danoprevir (ITMN-191/RG7227) in combination with pegylated interferon α-2a and ribavirin in patients with hepatitis C.

Published in:

2011

By:

Forestier N;
Larrey D;
Marcellin P;
Guyader D;
Patat A;
Rouzier R;
Smith PF;
Qin X;
Lim S;
Bradford W;
Porter S;
Seiwert SD;
Zeuzem S;
Forestier, Nicole;
Larrey, Dominique;
Marcellin, Patrick;
Guyader, Dominique;
Patat, Alain;
Rouzier, Regine;
Smith, Patrick F

Publication type:

journal article

Antiviral Activity of Danoprevir (ITMN-191/RG7227) in Combination With Pegylated Interferon α-2a and Ribavirin in Patients With Hepatitis C.

Published in:

2011

By:

Forestier, Nicole;
Larrey, Dominique;
Marcellin, Patrick;
Guyader, Dominique;
Patat, Alain;
Rouzier, Regine;
Smith, Patrick F.;
Qin, Xiaoli;
Lim, Sharlene;
Bradford, Williamson;
Porter, Steven;
Seiwert, Scott D.;
Zeuzem, Stefan

Publication type:

Abstract

Flumazenil antagonizes the central effects of zolpidem, an imidazopyridine hypnotic.

Published in:

Clinical Pharmacology & Therapeutics, 1994, v. 56, n. 4, p. 430, doi. 10.1038/clpt.1994.157

By:

Patat, Alain;
Naef, Marcus M;
Gessel, Elisabeth Van;
Forster, Alain;
Dubruc, Catherine;
Rosenzweig, Pierre

Publication type:

Article