Works by Pasero, Philippe

Results: 51

Defining replication origin efficiency using DNA fiber assays.

Published in:

Chromosome Research, 2010, v. 18, n. 1, p. 91, doi. 10.1007/s10577-009-9098-y

By:

Tuduri, Sandie;
Tourrière, Hélène;
Pasero, Philippe

Publication type:

Article

DDR Inc., one business, two associates.

Published in:

Current Genetics, 2019, v. 65, n. 2, p. 445, doi. 10.1007/s00294-018-0908-7

By:

Moriel-Carretero, María;
Pasero, Philippe;
Pardo, Benjamin

Publication type:

Article

DNA polymerase η modulates replication fork progression and DNA damage responses in platinum-treated human cells.

Published in:

Scientific Reports, 2013, p. 1, doi. 10.1038/srep03277

By:

Sokol, Anna M.;
Cruet-Hennequart, Séverine;
Pasero, Philippe;
Carty, Michael P.

Publication type:

Article

MRE11 and TREX1 control senescence by coordinating replication stress and interferon signaling.

Published in:

Nature Communications, 2024, v. 15, n. 1, p. 1, doi. 10.1038/s41467-024-49740-w

By:

Técher, Hervé;
Gopaul, Diyavarshini;
Heuzé, Jonathan;
Bouzalmad, Nail;
Leray, Baptiste;
Vernet, Audrey;
Mettling, Clément;
Moreaux, Jérôme;
Pasero, Philippe;
Lin, Yea-Lih

Publication type:

Article

DNA repair pathways in human multiple myeloma.

Published in:

Cell Cycle, 2013, v. 12, n. 17, p. 2760, doi. 10.4161/cc.25951

By:

Gourzones-Dmitriev, Claire;
Kassambara, Alboukadel;
Sahota, Surinder;
Rème, Thierry;
Moreaux, Jérôme;
Bourquard, Pascal;
Hose, Dirk;
Pasero, Philippe;
Constantinou, Angelos;
Klein, Bernard

Publication type:

Article

The Smc5/6 complex is required for dissolution of DNA-mediated sister chromatid linkages.

Published in:

Nucleic Acids Research, 2010, v. 38, n. 19, p. 6502, doi. 10.1093/nar/gkq546

By:

Bermúdez-López, Marcelino;
Ceschia, Audrey;
de Piccoli, Giacomo;
Colomina, Neus;
Pasero, Philippe;
Aragón, Luis;
Torres-Rosell, Jordi

Publication type:

Article

γ-Aminobutyric Acid-Induced Monocytic Reactive Oxygen Species Impair CD4 Restoration in Treated Adults With HIV-1.

Published in:

Journal of Infectious Diseases, 2025, v. 231, n. 5, p. 1246, doi. 10.1093/infdis/jiaf058

By:

Younas, Mehwish;
Gimenez, Sandrine;
Lin, Yea-Lih;
Mettling, Clément;
Maiorano, Domenico;
Reynes, Jacques;
Pasero, Philippe;
Rondard, Philippe;
Psomas, Christina K;
Corbeau, Pierre

Publication type:

Article

Hair follicle stem cell replication stress drives IFI16/STING-dependent inflammation in hidradenitis suppurativa.

Published in:

2020

By:

Orvain, Cindy;
Yea-Lih Lin;
Jean-Louis, Francette;
Hocini, Hakim;
Hersant, Barbara;
Bennasser, Yamina;
Ortonne, Nicolas;
Hotz, Claire;
Wolkenstein, Pierre;
Boniotto, Michele;
Tisserand, Pascaline;
Lefebvre, Cécile;
Lelièvre, Jean-Daniel;
Benkirane, Monsef;
Pasero, Philippe;
Lévy, Yves;
Hüe, Sophie;
Lin, Yea-Lih

Publication type:

journal article

i-BLESS is an ultra-sensitive method for detection of DNA double-strand breaks.

Published in:

Communications Biology, 2018, v. 1, n. 1, p. N.PAG, doi. 10.1038/s42003-018-0165-9

By:

Biernacka, Anna;
Zhu, Yingjie;
Skrzypczak, Magdalena;
Forey, Romain;
Pardo, Benjamin;
Grzelak, Marta;
Nde, Jules;
Mitra, Abhishek;
Kudlicki, Andrzej;
Crosetto, Nicola;
Pasero, Philippe;
Rowicka, Maga;
Ginalski, Krzysztof

Publication type:

Article

Multiplexed-Based Assessment of DNA Damage Response to Chemotherapies Using Cell Imaging Cytometry.

Published in:

International Journal of Molecular Sciences, 2022, v. 23, n. 10, p. 5701, doi. 10.3390/ijms23105701

By:

Vezzio-Vié, Nadia;
Kong-Hap, Marie-Alice;
Combès, Eve;
Andrade, Augusto Faria;
Del Rio, Maguy;
Pasero, Philippe;
Theillet, Charles;
Gongora, Céline;
Pourquier, Philippe

Publication type:

Article

Rtt101 and Mms1 in budding yeast form a CUL4<sup>DDB1</sup>-like ubiquitin ligase that promotes replication through damaged DNA.

Published in:

EMBO Reports, 2008, v. 9, n. 10, p. 1034, doi. 10.1038/embor.2008.155

By:

Zaidi, Iram Waris;
Rabut, Gwénaël;
Poveda, Ana;
Scheel, Hartmut;
Malmström, Johan;
Ulrich, Helle;
Hofmann, Kay;
Pasero, Philippe;
Peter, Matthias;
Luke, Brian

Publication type:

Article

A journey into the nucleus. Conference on Nuclear Structure and Dynamics.

Published in:

EMBO Reports, 2008, v. 9, n. 3, p. 228, doi. 10.1038/embor.2008.18

By:

Solovei, Irina;
Pasero, Philippe;
Visa, Neus

Publication type:

Article

High-resolution, ultrasensitive and quantitative DNA double-strand break labeling in eukaryotic cells using i-BLESS.

Published in:

Nature Protocols, 2021, v. 16, n. 2, p. 1034, doi. 10.1038/s41596-020-00448-3

By:

Biernacka, Anna;
Skrzypczak, Magdalena;
Zhu, Yingjie;
Pasero, Philippe;
Rowicka, Maga;
Ginalski, Krzysztof

Publication type:

Article

RNase H2 degrades toxic RNA:DNA hybrids behind stalled forks to promote replication restart.

Published in:

EMBO Journal, 2023, v. 42, n. 23, p. 1, doi. 10.15252/embj.2022113104

By:

Heuzé, Jonathan;
Kemiha, Samira;
Barthe, Antoine;
Vilarrubias, Alba Torán;
Aouadi, Elyès;
Aiello, Umberto;
Libri, Domenico;
Lin, Yea‐Lih;
Lengronne, Armelle;
Poli, Jérôme;
Pasero, Philippe

Publication type:

Article

A sterol‐PI(4)P exchanger modulates the Tel1/ATM axis of the DNA damage response.

Published in:

EMBO Journal, 2023, v. 42, n. 15, p. 1, doi. 10.15252/embj.2022112684

By:

Ovejero, Sara;
Kumanski, Sylvain;
Soulet, Caroline;
Azarli, Julie;
Pardo, Benjamin;
Santt, Olivier;
Constantinou, Angelos;
Pasero, Philippe;
Moriel‐Carretero, María

Publication type:

Article

Mrc1 and Rad9 cooperate to regulate initiation and elongation of DNA replication in response to DNA damage.

Published in:

EMBO Journal, 2018, v. 37, n. 21, p. N.PAG, doi. 10.15252/embj.201899319

By:

Bacal, Julien;
Moriel‐Carretero, María;
Pardo, Benjamin;
Barthe, Antoine;
Sharma, Sushma;
Chabes, Andrei;
Lengronne, Armelle;
Pasero, Philippe

Publication type:

Article

New Topoisomerase I mutations are associated with resistance to camptothecin.

Published in:

Molecular Cancer, 2011, v. 10, n. 1, p. 64, doi. 10.1186/1476-4598-10-64

By:

Gongora, Céline;
Vezzio-Vie, Nadia;
Tuduri, Sandie;
Denis, Vincent;
Causse, Annick;
Auzanneau, Céline;
Collod-Beroud, Gwenaëlle;
Coquelle, Arnaud;
Pasero, Philippe;
Pourquier, Philippe;
Martineau, Pierre;
Rio, Maguy Del

Publication type:

Article

Synergistic effect of inhibiting CHK2 and DNA replication on cancer cell growth.

Published in:

eLife, 2025, p. 1, doi. 10.7554/eLife.104718

By:

Coquel, Flavie;
Sing-Zong Ho;
Keng-Chang Tsai;
Chun-Yen Yang;
Aze, Antoine;
Devin, Julie;
Ting-Hsiang Chang;
Marie Kong-Hap;
Bioteau, Audrey;
Moreaux, Jerome;
Maiorano, Domenico;
Pourquier, Philippe;
Wen-Chin Yang;
Yea-Lih Lin;
Pasero, Philippe

Publication type:

Article

Common DNA structural features exhibited by eukaryotic ribosomal gene promoters.

Published in:

Nucleic Acids Research, 1996, v. 24, n. 12, p. 2204, doi. 10.1093/nar/24.12.2204

By:

Marilley, Monique;
Pasero, Philippe

Publication type:

Article

Does interference between replication and transcription contribute to genomic instability in cancer cells?

Published in:

Cell Cycle, 2010, v. 9, n. 10, p. 1886, doi. 10.4161/cc.9.10.11539

By:

Tuduri, Sandie;
Crabbe, Laure;
Tourrière, Hélène;
Coquelle, Arnaud;
Pasero, Philippe

Publication type:

Article

Upregulation of Error-Prone DNA Polymerases β and κ Slows Down Fork Progression Without Activating the Replication Checkpoint.

Published in:

Cell Cycle, 2007, v. 6, n. 4, p. 471, doi. 10.4161/cc.6.4.3857

By:

Pillaire, Marie-Jeanne;
Betous, Rémy;
Conti, Chiara;
Czaplicki, Jerzy;
Pasero, Philippe;
Bensimon, Aaron;
Cazaux, Christophe;
Hoffmann, Jean-Sébastien

Publication type:

Article

Multiple Roles of Replication Forks in S Phase Checkpoints.

Published in:

Cell Cycle, 2003, v. 2, n. 6, p. 568, doi. 10.4161/cc.2.6.577

By:

Pasero, Philippe;
Shimada, Kenji;
Dunck, Bernard P.

Publication type:

Article

Nuclear DNA replication and repair in parasites of the genus Leishmania : Exploiting differences to develop innovative therapeutic approaches.

Published in:

Critical Reviews in Microbiology, 2017, v. 43, n. 2, p. 156, doi. 10.1080/1040841X.2016.1188758

By:

Uzcanga, Graciela;
Lara, Eliana;
Gutiérrez, Fernanda;
Beaty, Doyle;
Beske, Timo;
Teran, Rommy;
Navarro, Juan-Carlos;
Pasero, Philippe;
Benítez, Washington;
Poveda, Ana

Publication type:

Article

Histone H3 Lysine 56 Acetylation and the Response to DNA Replication Fork Damage.

Published in:

Molecular & Cellular Biology, 2012, v. 32, n. 1, p. 6, doi. 10.1128/MCB.05415-11

By:

Wurtele, Hugo;
Kaiser, Gitte Schalck;
Bacal, Julien;
St-Hilaire, Edlie;
Lee, Eun-Hye;
Tsao, Sarah;
Dorn, Jonas;
Maddox, Paul;
Lisby, Michael;
Pasero, Philippe;
Verreault, Alain

Publication type:

Article

Phosphorylation of Slx4 by Mec1 and Tel1 Regulates the Single-Strand Annealing Mode of DNA Repair in Budding Yeast.

Published in:

Molecular & Cellular Biology, 2007, v. 27, n. 18, p. 15, doi. 10.1128/MCB.00135-07

By:

Flott, Sonja;
Alabert, Constance;
Toh, Geraldine W.;
Toth, Rachel;
Sugawara, Neal;
Campbell, David G.;
Haber, James E.;
Pasero, Philippe;
Rouse, John

Publication type:

Article

New histone supply regulates replication fork speed and PCNA unloading.

Published in:

Journal of Cell Biology, 2014, v. 204, n. 1, p. 29, doi. 10.1083/jcb.201305017

By:

Mejlvang, Jakob;
Yunpeng Feng;
Alabert, Constance;
Neelsen, Kai J.;
Jasencakova, Zuzana;
Xiaobei Zhao;
Lees, Michael;
Sandelin, Albin;
Pasero, Philippe;
Lopes, Massimo;
Groth, Anja

Publication type:

Article

Rrm3 and Pif1 division of labor during replication through leading and lagging strand G-quadruplex.

Published in:

Nucleic Acids Research, 2024, v. 52, n. 4, p. 1753, doi. 10.1093/nar/gkad1205

By:

Varon, Mor;
Dovrat, Daniel;
Heuzé, Jonathan;
Tsirkas, Ioannis;
Singh, Saurabh P;
Pasero, Philippe;
Galletto, Roberto;
Aharoni, Amir

Publication type:

Article

Senataxin resolves RNA:DNA hybrids forming at DNA double-strand breaks to prevent translocations.

Published in:

Nature Communications, 2018, v. 9, n. 1, p. 1, doi. 10.1038/s41467-018-02894-w

By:

Cohen, Sarah;
Puget, Nadine;
Yea-Lih Lin;
Clouaire, Thomas;
Aguirrebengoa, Marion;
Rocher, Vincent;
Pasero, Philippe;
Canitrot, Yvan;
Legube, Gaëlle

Publication type:

Article

Transcription/Replication Conflicts in Tumorigenesis and Their Potential Role as Novel Therapeutic Targets in Multiple Myeloma.

Published in:

Cancers, 2021, v. 13, n. 15, p. 3755, doi. 10.3390/cancers13153755

By:

Dutrieux, Laure;
Lin, Yea-Lih;
Lutzmann, Malik;
Rodriguez, Raphaël;
Cogné, Michel;
Pasero, Philippe;
Moreaux, Jérôme

Publication type:

Article

DNA repair in diffuse large B-cell lymphoma: a molecular portrait.

Published in:

British Journal of Haematology, 2015, v. 169, n. 2, p. 296, doi. 10.1111/bjh.13206

By:

Bret, Caroline;
Klein, Bernard;
Cartron, Guillaume;
Schved, Jean‐François;
Constantinou, Angelos;
Pasero, Philippe;
Moreaux, Jérôme

Publication type:

Article

dNTP pools determine fork progression and origin usage under replication stress.

Published in:

EMBO Journal, 2012, v. 31, n. 4, p. 883, doi. 10.1038/emboj.2011.470

By:

Poli, Jérôme;
Tsaponina, Olga;
Crabbé, Laure;
Keszthelyi, Andrea;
Pantesco, Véronique;
Chabes, Andrei;
Lengronne, Armelle;
Pasero, Philippe

Publication type:

Article

RNAi-based screening identifies the Mms22L-Nfkbil2 complex as a novel regulator of DNA replication in human cells.

Published in:

EMBO Journal, 2010, v. 29, n. 24, p. 4210, doi. 10.1038/emboj.2010.304

By:

Piwko, Wojciech;
Olma, Michael H;
Held, Michael;
Bianco, Julien N;
Pedrioli, Patrick G A;
Hofmann, Kay;
Pasero, Philippe;
Gerlich, Daniel W;
Peter, Matthias

Publication type:

Article

The MRX complex stabilizes the replisome independently of the S phase checkpoint during replication stress.

Published in:

EMBO Journal, 2009, v. 28, n. 8, p. 1142, doi. 10.1038/emboj.2009.60

By:

Tittel-Elmer, Mireille;
Alabert, Constance;
Pasero, Philippe;
Cobb, Jennifer A.

Publication type:

Article

Differential regulation of homologous recombination at DNA breaks and replication forks by the Mrc1 branch of the S-phase checkpoint.

Published in:

EMBO Journal, 2009, v. 28, n. 8, p. 1131, doi. 10.1038/emboj.2009.75

By:

Alabert, Constance;
Bianco, Julien N.;
Pasero, Philippe

Publication type:

Article

An essential role for Orc6 in DNA replication through maintenance of pre-replicative complexes.

Published in:

EMBO Journal, 2006, v. 25, n. 21, p. 5150, doi. 10.1038/sj.emboj.7601391

By:

Semple, Jeffrey W.;
Da-Silva, Lance F.;
Jervis, Eric J.;
Ah-Kee, Jennifer;
Al-Attar, Hyder;
Kummer, Lutz;
Heikkila, John J.;
Pasero, Philippe;
Duncker, Bernard P.

Publication type:

Article

Nucleotide-resolution DNA double-strand break mapping by next-generation sequencing.

Published in:

Nature Methods, 2013, v. 10, n. 4, p. 361, doi. 10.1038/nmeth.2408

By:

Crosetto, Nicola;
Mitra, Abhishek;
Silva, Maria Joao;
Bienko, Magda;
Dojer, Norbert;
Wang, Qi;
Karaca, Elif;
Chiarle, Roberto;
Skrzypczak, Magdalena;
Ginalski, Krzysztof;
Pasero, Philippe;
Rowicka, Maga;
Dikic, Ivan

Publication type:

Article

Analysis of replication profiles reveals key role of RFC-Ctf18 in yeast replication stress response.

Published in:

Nature Structural & Molecular Biology, 2010, v. 17, n. 11, p. 1391, doi. 10.1038/nsmb.1932

By:

Crabbé, Laure;
Thomas, Aubin;
Pantesco, Véronique;
De Vos, John;
Pasero, Philippe;
Lengronne, Armelle

Publication type:

Article

Involvement of a chromatin remodeling complex in damage tolerance during DNA replication.

Published in:

Nature Structural & Molecular Biology, 2009, v. 16, n. 11, p. 1167, doi. 10.1038/nsmb.1686

By:

Falbo, Karina B.;
Alabert, Constance;
Katou, Yuki;
Wu, Su;
Han, Junhong;
Wehr, Tammy;
Xiao, Jing;
He, Xiangwei;
Zhang, Zhiguo;
Shi, Yang;
Shirahige, Katsu;
Pasero, Philippe;
Shen, Xuetong

Publication type:

Article

RECQ helicases are deregulated in hematological malignancies in association with a prognostic value.

Published in:

Biomarker Research, 2016, v. 4, p. 1, doi. 10.1186/s40364-016-0057-4

By:

Viziteu, Elena;
Kassambara, Alboukadel;
Pasero, Philippe;
Klein, Bernard;
Moreaux, Jerome

Publication type:

Article

Topoisomerase I suppresses genomic instability by preventing interference between replication and transcription.

Published in:

2010

By:

Tuduri, Sandie;
Crabbé, Laure;
Conti, Chiara;
Tourrière, Hélène;
Holtgreve-Grez, Heidi;
Jauch, Anna;
Pantesco, Véronique;
De Vos, John;
Thomas, Aubin;
Theillet, Charles;
Pommier, Yves;
Tazi, Jamal;
Coquelle, Arnaud;
Pasero, Philippe

Publication type:

Correction Notice

Topoisomerase I suppresses genomic instability by preventing interference between replication and transcription.

Published in:

Nature Cell Biology, 2009, v. 11, n. 11, p. 1315, doi. 10.1038/ncb1984

By:

Tuduri, Sandie;
Crabbé, Laure;
Conti, Chiara;
Tourrière, Hélène;
Holtgreve-Grez, Heidi;
Jauch, Anna;
Pantesco, Véronique;
De Vos, John;
Thomas, Aubin;
Theillet, Charles;
Pommier, Yves;
Tazi, Jamal;
Coquelle, Arnaud;
Pasero, Philippe

Publication type:

Article

Resolution of R-loops by INO80 promotes DNA replication and maintains cancer cell proliferation and viability.

Published in:

Nature Communications, 2020, v. 11, n. 1, p. N.PAG, doi. 10.1038/s41467-020-18306-x

By:

Prendergast, Lisa;
McClurg, Urszula L.;
Hristova, Rossitsa;
Berlinguer-Palmini, Rolando;
Greener, Sarah;
Veitch, Katie;
Hernandez, Inmaculada;
Pasero, Philippe;
Rico, Daniel;
Higgins, Jonathan M. G.;
Gospodinov, Anastas;
Papamichos-Chronakis, Manolis

Publication type:

Article

Topoisomerase 1 prevents replication stress at R-loop-enriched transcription termination sites.

Published in:

Nature Communications, 2020, v. 11, n. 1, p. 1, doi. 10.1038/s41467-020-17858-2

By:

Promonet, Alexy;
Padioleau, Ismaël;
Liu, Yaqun;
Sanz, Lionel;
Biernacka, Anna;
Schmitz, Anne-Lyne;
Skrzypczak, Magdalena;
Sarrazin, Amélie;
Mettling, Clément;
Rowicka, Maga;
Ginalski, Krzysztof;
Chedin, Frédéric;
Chen, Chun-Long;
Lin, Yea-Lih;
Pasero, Philippe

Publication type:

Article

Ethanol exposure increases mutation rate through error-prone polymerases.

Published in:

Nature Communications, 2020, v. 11, n. 1, p. 1, doi. 10.1038/s41467-020-17447-3

By:

Voordeckers, Karin;
Colding, Camilla;
Grasso, Lavinia;
Pardo, Benjamin;
Hoes, Lore;
Kominek, Jacek;
Gielens, Kim;
Dekoster, Kaat;
Gordon, Jonathan;
Van der Zande, Elisa;
Bircham, Peter;
Swings, Toon;
Michiels, Jan;
Van Loo, Peter;
Nuyts, Sandra;
Pasero, Philippe;
Lisby, Michael;
Verstrepen, Kevin J.

Publication type:

Article

Topoisomerase I prevents transcription-replication conflicts at transcription termination sites.

Published in:

Molecular & Cellular Oncology, 2021, v. 8, n. 1, p. 1, doi. 10.1080/23723556.2020.1843951

By:

Liu, Yaqun;
Lin, Yea-Lih;
Pasero, Philippe;
Chen, Chun-Long

Publication type:

Article

Overexpression of the Fork Protection Complex: a strategy to tolerate oncogene-induced replication stress in cancer cells.

Published in:

Molecular & Cellular Oncology, 2019, v. 6, n. 4, p. N.PAG, doi. 10.1080/23723556.2019.1607455

By:

Pasero, Philippe;
Tourrière, Hélène

Publication type:

Article

Homologous recombination and Mus81 promote replication completion in response to replication fork blockage.

Published in:

EMBO Reports, 2020, v. 21, n. 7, p. 1, doi. 10.15252/embr.201949367

By:

Pardo, Benjamin;
Moriel‐Carretero, María;
Vicat, Thibaud;
Aguilera, Andrés;
Pasero, Philippe

Publication type:

Article

Closing the MCM cycle at replication termination sites.

Published in:

EMBO Reports, 2014, v. 15, n. 12, p. 1226, doi. 10.15252/embr.201439774

By:

Lengronne, Armelle;
Pasero, Philippe

Publication type:

Article

Combined inhibition of Wee1 and Chk1 as a therapeutic strategy in multiple myeloma.

Published in:

Frontiers in Oncology, 2023, p. 1, doi. 10.3389/fonc.2023.1271847

By:

Bruyer, Angélique;
Dutrieux, Laure;
de Boussac, Hugues;
Martin, Thibaut;
Chemlal, Djamila;
Robert, Nicolas;
Requirand, Guilhem;
Cartron, Guillaume;
Vincent, Laure;
Herbaux, Charles;
Lutzmann, Malik;
Bret, Caroline;
Pasero, Philippe;
Moreaux, Jérôme;
Ovejero, Sara

Publication type:

Article

qDSB-Seq is a general method for genome-wide quantification of DNA double-strand breaks using sequencing.

Published in:

Nature Communications, 2019, v. 10, n. 1, p. 1, doi. 10.1038/s41467-019-10332-8

By:

Yingjie Zhu;
Biernacka, Anna;
Pardo, Benjamin;
Dojer, Norbert;
Forey, Romain;
Skrzypczak, Magdalena;
Fongang, Bernard;
Nde, Jules;
Yousefi, Razie;
Pasero, Philippe;
Ginalski, Krzysztof;
Rowicka, Maga

Publication type:

Article