Works by Paschen, Wulf

Results: 38

Novel Modification of Potassium Chloride Induced Cardiac Arrest Model for Aged Mice.

Published in:

Aging & Disease, 2018, v. 9, n. 1, p. 31, doi. 10.14336/AD.2017.0221

By:

Huaqin Liu;
Zhui Yu;
Ying Li;
Bin Xu;
Baihui Yan;
Paschen, Wulf;
Warner, David S.;
Wei Yang;
Huaxin Sheng

Publication type:

Article

Small ubiquitin‐like modifier 2 (SUMO2) is critical for memory processes in mice.

Published in:

FASEB Journal, 2020, v. 34, n. 11, p. 14750, doi. 10.1096/fj.202000850RR

By:

Yu, Shu;
Galeffi, Francesca;
Rodriguiz, Ramona M.;
Wang, Zhuoran;
Shen, Yuntian;
Lyu, Jingjun;
Li, Ran;
Bernstock, Joshua D.;
Johnson, Kory R.;
Liu, Shuai;
Sheng, Huaxin;
Turner, Dennis A.;
Wetsel, William C.;
Paschen, Wulf;
Yang, Wei

Publication type:

Article

Small ubiquitin-like modifier 1-3 is activated in human astrocytic brain tumors and is required for glioblastoma cell survival.

Published in:

Cancer Science, 2013, v. 104, n. 1, p. 70, doi. 10.1111/cas.12047

By:

Yang, Wei;
Wang, Liangli;
Roehn, Gabriele;
Pearlstein, Robert D.;
Ali‐Osman, Francis;
Pan, Hongjie;
Goldbrunner, Roland;
Krantz, Matthew;
Harms, Christoph;
Paschen, Wulf

Publication type:

Article

SUMOylation in brain ischemia: Patterns, targets, and translational implications.

Published in:

Journal of Cerebral Blood Flow & Metabolism, 2018, v. 38, n. 1, p. 5, doi. 10.1177/0271678X17742260

By:

Bernstock, Joshua D.;
Yang, Wei;
Ye, Daniel G.;
Shen, Yuntian;
Pluchino, Stefano;
Lee, Yang-Ja;
Hallenbeck, John M.;
Paschen, Wulf

Publication type:

Article

Is age a key factor contributing to the disparity between success of neuroprotective strategies in young animals and limited success in elderly stroke patients? Focus on protein homeostasis.

Published in:

Journal of Cerebral Blood Flow & Metabolism, 2017, v. 37, n. 10, p. 3318, doi. 10.1177/0271678X17723783

By:

Wei Yang;
Paschen, Wulf

Publication type:

Article

Activation of the ATF6 branch of the unfolded protein response in neurons improves stroke outcome.

Published in:

Journal of Cerebral Blood Flow & Metabolism, 2017, v. 37, n. 3, p. 1069, doi. 10.1177/0271678X16650218

By:

Zhui Yu;
Huaxin Sheng;
Shuai Liu;
Shengli Zhao;
Glembotski, Christopher C.;
Warner, David S.;
Paschen, Wulf;
Wei Yang

Publication type:

Article

Unfolded protein response in brain ischemia: A timely update.

Published in:

Journal of Cerebral Blood Flow & Metabolism, 2016, v. 36, n. 12, p. 2044, doi. 10.1177/0271678X16674488

By:

Wei Yang;
Paschen, Wulf

Publication type:

Article

O-linked β-N-acetylglucosamine modification of proteins is activated in post-ischemic brains of young but not aged mice: Implications for impaired functional recovery from ischemic stress.

Published in:

Journal of Cerebral Blood Flow & Metabolism, 2016, v. 36, n. 2, p. 393, doi. 10.1177/0271678X15608393

By:

Shuai Liu;
Huaxin Sheng;
Zhui Yu;
Wulf Paschen;
Wei Yang

Publication type:

Article

Characterization of the ubiquitin-modified proteome regulated by transient forebrain ischemia.

Published in:

Journal of Cerebral Blood Flow & Metabolism, 2014, v. 34, n. 3, p. 425, doi. 10.1038/jcbfm.2013.210

By:

Iwabuchi, Masahiro;
Sheng, Huaxin;
Thompson, JWill;
Wang, Liangli;
Dubois, Laura G;
Gooden, David;
Moseley, MArthur;
Paschen, Wulf;
Yang, Wei

Publication type:

Article

SUMO2/3 conjugation is an endogenous neuroprotective mechanism.

Published in:

Journal of Cerebral Blood Flow & Metabolism, 2011, v. 31, n. 11, p. 2152, doi. 10.1038/jcbfm.2011.112

By:

Datwyler, Anna Lena;
Lättig-Tünnemann, Gisela;
Yang, Wei;
Paschen, Wulf;
Lee, Sabrina Lin Lin;
Dirnagl, Ulrich;
Endres, Matthias;
Harms, Christoph

Publication type:

Article

Deep hypothermia markedly activates the small ubiquitin-like modifier conjugation pathway; implications for the fate of cells exposed to transient deep hypothermic cardiopulmonary bypass.

Published in:

Journal of Cerebral Blood Flow & Metabolism, 2009, v. 29, n. 5, p. 886, doi. 10.1038/jcbfm.2009.16

By:

Wei Yang;
Qing Ma;
Mackensen, G. Burkhard;
Paschen, Wulf

Publication type:

Article

Transient focal cerebral ischemia induces a dramatic activation of small ubiquitin-like modifier conjugation.

Published in:

Journal of Cerebral Blood Flow & Metabolism, 2008, v. 28, n. 5, p. 892, doi. 10.1038/sj.jcbfm.9600601

By:

Wei Yang;
Huaxin Sheng;
Warner, David S.;
Paschen, Wulf

Publication type:

Article

Transient global cerebral ischemia induces a massive increase in protein sumoylation.

Published in:

Journal of Cerebral Blood Flow & Metabolism, 2008, v. 28, n. 2, p. 269, doi. 10.1038/sj.jcbfm.9600523

By:

Wei Yang;
Huaxin Sheng;
Warner, David S.;
Paschen, Wulf

Publication type:

Article

Shutdown of Translation: Lethal or Protective? Unfolded Protein Response Versus Apoptosis.

Published in:

Journal of Cerebral Blood Flow & Metabolism, 2003, v. 23, n. 7, p. 773, doi. 10.1097/01.WCB.0000075009.47474.F9

By:

Wulf Paschen

Publication type:

Article

Transient Cerebral Ischemia Activates Processing of xbp1 Messenger RNA Indicative of Endoplasmic Reticulum Stress.

Published in:

Journal of Cerebral Blood Flow & Metabolism, 2003, v. 23, n. 4, p. 449, doi. 10.1097/01.WCB.0000054216.21675.AC

By:

Wulf Paschen;
Christoph Aufenberg;
Svenja Hotop;
Thorsten Mengesdorf

Publication type:

Article

Disturbances of the Functioning of Endoplasmic Reticulum: A Key Mechanism Underlying Neuronal Cell Injury?

Published in:

Journal of Cerebral Blood Flow & Metabolism, 1999, v. 19, n. 1, p. 1, doi. 10.1097/00004647-199901000-00001

By:

Paschen, Wulf;
Doutheil, Jens

Publication type:

Article

RNA Editing of Glutamate Receptor Subunits GluR2, GluR5, and GluR6 in Transient Cerebral Ischemia in the Rat.

Published in:

Journal of Cerebral Blood Flow & Metabolism, 1996, v. 16, n. 4, p. 548, doi. 10.1097/00004647-199607000-00004

By:

Paschen, Wulf;
Schmitt, Justina;
Uto, Akira

Publication type:

Article

SUMO2 is essential while SUMO3 is dispensable for mouse embryonic development.

Published in:

EMBO Reports, 2014, v. 15, n. 8, p. 878, doi. 10.15252/embr.201438534

By:

Wang, Liangli;
Wansleeben, Carolien;
Zhao, Shengli;
Miao, Pei;
Paschen, Wulf;
Yang, Wei

Publication type:

Article

Neuron-specific Sumo1-3 knockdown in mice impairs episodic and fear memories.

Published in:

Journal of Psychiatry & Neuroscience, 2014, v. 39, n. 4, p. 259, doi. 10.1503/jpn.130148

By:

Liangli Wang;
Rodriguiz, Ramona M.;
Wetsel, William C.;
Huaxin Sheng;
Shengli Zhao;
Xiaozhi Liu;
Paschen, Wulf;
Wei Yang

Publication type:

Article

GADD34 protein levels increase after transient ischemia in the cortex but not in the CA1 subfield: implications for post-ischemic recovery of protein synthesis in ischemia-resistant cells.

Published in:

Journal of Neurochemistry, 2004, v. 90, n. 3, p. 694, doi. 10.1111/j.1471-4159.2004.02555.x

By:

Paschen, Wulf;
Hayashi, Takeshi;
Saito, Atsushi;
Chan, Pak H.

Publication type:

Article

Brain trauma induces X-box protein 1 processing indicative of activation of the endoplasmic reticulum unfolded protein response.

Published in:

Journal of Neurochemistry, 2004, v. 88, n. 4, p. 983, doi. 10.1046/j.1471-4159.2003.02218.x

By:

Paschen, Wulf;
Yatsiv, Ido;
Shoham, Shai;
Shohami, Esther

Publication type:

Article

Brain trauma induces X-box protein 1 processing indicative of activation of the endoplasmic reticulum unfolded protein response.

Published in:

Journal of Neurochemistry, 2004, v. 88, n. 3, p. 983, doi. 10.1046/j.1471-4159.2003.02218.x

By:

Paschen, Wulf;
Yatsiv, Ido;
Shoham, Shai;
Shohami, Esther

Publication type:

Article

Conditions associated with ER dysfunction activate homer 1a expression.

Published in:

Journal of Neurochemistry, 2003, v. 86, n. 5, p. 1108, doi. 10.1046/j.1471-4159.2003.01884.x

By:

Paschen, Wulf;
Mengesdorf, Thorsten

Publication type:

Article

Effect of Transient Focal Ischemia of Mouse Brain on Energy State and NAD Levels.

Published in:

Journal of Neurochemistry, 2000, v. 75, n. 4, p. 1675, doi. 10.1046/j.1471-4159.2000.0751675.x

By:

Paschen, Wulf;
Oláh, Laszlo;
Mies, Günter

Publication type:

Article

Temporal Analysis of Changes in Neuronal c- fos mRNA Levels Induced by Depletion of Endoplasmic Reticulum Calcium Stores: Effect of Clamping Cytoplasmic Calcium Activity at Resting Levels.

Published in:

Journal of Neurochemistry, 1997, v. 69, n. 6, p. 2538, doi. 10.1046/j.1471-4159.1997.69062538.x

By:

Gissel, Cornelia;
Doutheil, Jens;
Paschen, Wulf

Publication type:

Article

Depletion of Neuronal Endoplasmic Reticulum Calcium Stores by Thapsigargin: Effect on Protein Synthesis.

Published in:

Journal of Neurochemistry, 1996, v. 67, n. 4, p. 1735, doi. 10.1046/j.1471-4159.1996.67041735.x

By:

Paschen, Wulf;
Doutheil, Jens;
Gissel, Cornelia;
Treiman, Marek

Publication type:

Article

Comparison of In Vitro Ischemia-Induced Disturbances in Energy Metabolism and Protein Synthesis in the Hippocampus of Rats and Gerbils.

Published in:

Journal of Neurochemistry, 1995, v. 65, n. 4, p. 1692, doi. 10.1046/j.1471-4159.1995.65041692.x

By:

Paschen, Wulf;
Djuricic, Bogdan

Publication type:

Article

RNA Editing of the Glutamate Receptor Subunits GluR2 and GluR6 in Human Brain Tissue.

Published in:

Journal of Neurochemistry, 1994, v. 63, n. 5, p. 1596, doi. 10.1046/j.1471-4159.1994.63051596.x

By:

Paschen, Wulf;
Hedreen, John C.;
Ross, Christopher A.

Publication type:

Article

Polyamine Metabolism in Experimental Brain Tumors of Rat.

Published in:

Journal of Neurochemistry, 1993, v. 60, n. 2, p. 417, doi. 10.1111/j.1471-4159.1993.tb03167.x

By:

Ernestus, Ralf-Ingo;
Röhn, Gabriele;
Hossmann, Konstantin-Alexander;
Paschen, Wulf

Publication type:

Article

Cerebral Polyamine Metabolism in Reversible Hypoglycemia of Rat: Relationship to Energy Metabolites and Calcium.

Published in:

Journal of Neurochemistry, 1991, v. 57, n. 1, p. 204, doi. 10.1111/j.1471-4159.1991.tb02117.x

By:

Paschen, Wulf;
Bengtsson, Finn;
Röhn, Gabriele;
Bonnekoh, Petra;
Siesjö, Bo;
Hossmann, Konstantin-Alexander

Publication type:

Article

Aging Is Associated With Impaired Activation of Protein Homeostasis-Related Pathways After Cardiac Arrest in Mice.

Published in:

2018

By:

Yuntian Shen;
Baihui Yan;
Qiang Zhao;
Zhuoran Wang;
Jiangbo Wu;
Jiafa Ren;
Wei Wang;
Shu Yu;
Huaxin Sheng;
Crowley, Steven D.;
Fei Ding;
Paschen, Wulf;
Wei Yang;
Shen, Yuntian;
Yan, Baihui;
Zhao, Qiang;
Wang, Zhuoran;
Wu, Jiangbo;
Ren, Jiafa;
Wang, Wei

Publication type:

journal article

Moderate hypothermia induces marked increase in levels and nuclear accumulation of SUMO2/3-conjugated proteins in neurons.

Published in:

Journal of Neurochemistry, 2012, v. 123, n. 3, p. 349, doi. 10.1111/j.1471-4159.2012.07916.x

By:

Wang, Liangli;
Ma, Qing;
Yang, Wei;
Mackensen, G. Burkhard;
Paschen, Wulf

Publication type:

Article

Cerebral ischemia/stroke and small ubiquitin-like modifier (SUMO) conjugation – a new target for therapeutic intervention?

Published in:

Journal of Neurochemistry, 2008, v. 106, n. 3, p. 989, doi. 10.1111/j.1471-4159.2008.05404.x

By:

Yang, Wei;
Sheng, Huaxin;
Homi, H. Mayumi;
Warner, David S.;
Paschen, Wulf

Publication type:

Article

SUMO proteomics to decipher the SUMO-modified proteome regulated by various diseases.

Published in:

Proteomics, 2015, v. 15, n. 5/6, p. 1181, doi. 10.1002/pmic.201400298

By:

Yang, Wei;
Paschen, Wulf

Publication type:

Article

Ornithine Decarboxylase Activity and Putrescine Levels in Reversible Cerebral Ischemia of Mongolian Gerbils: effect of Barbiturate.

Published in:

Journal of Cerebral Blood Flow & Metabolism, 1990, v. 10, n. 2, p. 236, doi. 10.1038/jcbfm.1990.40

By:

Paschen, Wulf;
Hallmayer, Joachim;
Mies, Günter;
Röhn, Gabriele

Publication type:

Article

Endoplasmic Reticulum Stress.

Published in:

Annals of the New York Academy of Sciences, 2007, v. 1113, p. 58, doi. 10.1196/annals.1391.007

By:

BÁNHEGYI, GÁBOR;
BAUMEISTER, PETER;
BENEDETTI, ANGELO;
DONG, DEZHENG;
FU, YONG;
LEE, AMY S.;
LI, JIANZE;
MAO, CHANGHUI;
MARGITTAI, ÉVA;
NI, MIN;
PASCHEN, WULF;
PICCIRELLA, SIMONA;
SENESI, SILVIA;
SITIA, ROBERTO;
WANG, MIAO;
YANG, WEI

Publication type:

Article

The requirement of SUMO2/3 for SENP2 mediated extraembryonic and embryonic development.

Published in:

Developmental Dynamics, 2020, v. 249, n. 2, p. 237, doi. 10.1002/dvdy.125

By:

Yu, H‐M Ivy;
Hsu, Trunee;
Maruyama, Eri O;
Paschen, Wulf;
Yang, Wei;
Hsu, Wei

Publication type:

Article

Metabolic Imaging in Microregions of Tumors and Normal Tissues With Bioluminescence and Photon Counting.

Published in:

JNCI: Journal of the National Cancer Institute, 1988, v. 80, n. 11, p. 842

By:

Mueller-klieser, Wolfgang;
Walenta, Stefana;
Paschen, Wulf;
Kallinowski, Friedrich;
Vaupel, Peter

Publication type:

Article