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Potent acyl-CoA synthetase 10 inhibitors kill Plasmodium falciparum by disrupting triglyceride formation.
Published in:
Nature Communications, 2023, v. 14, n. 1, p. 1, doi. 10.1038/s41467-023-36921-2
By:
- Bopp, Selina;
- Pasaje, Charisse Flerida A.;
- Summers, Robert L.;
- Magistrado-Coxen, Pamela;
- Schindler, Kyra A.;
- Corpas-Lopez, Victoriano;
- Yeo, Tomas;
- Mok, Sachel;
- Dey, Sumanta;
- Smick, Sebastian;
- Nasamu, Armiyaw S.;
- Demas, Allison R.;
- Milne, Rachel;
- Wiedemar, Natalie;
- Corey, Victoria;
- Gomez-Lorenzo, Maria De Gracia;
- Franco, Virginia;
- Early, Angela M.;
- Lukens, Amanda K.;
- Milner, Danny
Publication type:
Article
Selective expression of variant surface antigens enables Plasmodium falciparum to evade immune clearance in vivo.
Published in:
Nature Communications, 2022, v. 13, n. 1, p. 1, doi. 10.1038/s41467-022-31741-2
By:
- Chew, Marvin;
- Ye, Weijian;
- Omelianczyk, Radoslaw Igor;
- Pasaje, Charisse Flerida;
- Hoo, Regina;
- Chen, Qingfeng;
- Niles, Jacquin C.;
- Chen, Jianzhu;
- Preiser, Peter
Publication type:
Article
Lack of association of RAD51 genetic variations with hepatitis B virus clearance and occurrence of hepatocellular carcinoma in a Korean population.
Published in:
Journal of Medical Virology, 2011, v. 83, n. 11, p. 1892, doi. 10.1002/jmv.22122
By:
- Pasaje, Charisse Flerida A.;
- Kim, Jeong-Hyun;
- Park, Byung-Lae;
- Cheong, Hyun Sub;
- Bae, Joon Seol;
- Park, Tae-Joon;
- Lee, Jin-Sol;
- Kim, Yongha;
- Lee, Hyo-Suk;
- Koh, InSong;
- Kim, Yoon Jun;
- Shin, Hyoung Doo
Publication type:
Article
Phosphatidylinositol 3-phosphate and Hsp70 protect Plasmodium falciparum from heat-induced cell death.
Published in:
eLife, 2020, p. 1, doi. 10.7554/eLife.56773
By:
- Kuan-Yi Lu;
- Pasaje, Charisse Flerida A.;
- Srivastava, Tamanna;
- Loiselle, David R.;
- Niles, Jacquin C.;
- Derbyshire, Emily
Publication type:
Article
UBE3C genetic variations as potent markers of nasal polyps in Korean asthma patients.
Published in:
Journal of Human Genetics, 2011, v. 56, n. 11, p. 797, doi. 10.1038/jhg.2011.104
By:
- Pasaje, Charisse Flerida A;
- Kim, Jeong-Hyun;
- Park, Byung-Lae;
- Park, Jong-Sook;
- Uh, Soo-Taek;
- Kim, Mi-Kyeong;
- Park, Choon-Sik;
- Shin, Hyoung Doo
Publication type:
Article
Genetic association analysis of TAP1 and TAP2 polymorphisms with aspirin exacerbated respiratory disease and its FEV1 decline.
Published in:
Journal of Human Genetics, 2011, v. 56, n. 9, p. 652, doi. 10.1038/jhg.2011.75
By:
- Kim, Jeong-Hyun;
- Park, Byung-Lae;
- Pasaje, Charisse Flerida A;
- Bae, Joon Seol;
- Park, Jong Sook;
- Park, Sung Woo;
- Uh, Soo-Taek;
- Kim, Mi-Kyeong;
- Choi, Inseon S;
- Cho, Sang Heon;
- Choi, Byoung Whui;
- Park, Choon-Sik;
- Shin, Hyoung Doo
Publication type:
Article
Genome-wide association analysis of copy number variations in subarachnoid aneurysmal hemorrhage.
Published in:
Journal of Human Genetics, 2010, v. 55, n. 11, p. 726, doi. 10.1038/jhg.2010.97
By:
- Bae, Joon Seol;
- Cheong, Hyun Sub;
- Park, Byung Lae;
- Kim, Lyoung Hyo;
- Park, Tae Joon;
- Kim, Jason Yongha;
- Pasaje, Charisse Flerida A;
- Lee, Jin Sol;
- Cui, Tailin;
- Inoue, Ituro;
- Shin, Hyoung Doo
Publication type:
Article
Preclinical characterization and target validation of the antimalarial pantothenamide MMV693183.
Published in:
Nature Communications, 2022, v. 13, n. 1, p. 1, doi. 10.1038/s41467-022-29688-5
By:
- de Vries, Laura E.;
- Jansen, Patrick A. M.;
- Barcelo, Catalina;
- Munro, Justin;
- Verhoef, Julie M. J.;
- Pasaje, Charisse Flerida A.;
- Rubiano, Kelly;
- Striepen, Josefine;
- Abla, Nada;
- Berning, Luuk;
- Bolscher, Judith M.;
- Demarta-Gatsi, Claudia;
- Henderson, Rob W. M.;
- Huijs, Tonnie;
- Koolen, Karin M. J.;
- Tumwebaze, Patrick K.;
- Yeo, Tomas;
- Aguiar, Anna C. C.;
- Angulo-Barturen, Iñigo;
- Churchyard, Alisje
Publication type:
Article
Functional genomics of RAP proteins and their role in mitoribosome regulation in Plasmodium falciparum.
Published in:
Nature Communications, 2022, v. 13, n. 1, p. 1, doi. 10.1038/s41467-022-28981-7
By:
- Hollin, Thomas;
- Abel, Steven;
- Falla, Alejandra;
- Pasaje, Charisse Flerida A.;
- Bhatia, Anil;
- Hur, Manhoi;
- Kirkwood, Jay S.;
- Saraf, Anita;
- Prudhomme, Jacques;
- De Souza, Amancio;
- Florens, Laurence;
- Niles, Jacquin C.;
- Le Roch, Karine G.
Publication type:
Article
A conserved complex of microneme proteins mediates rhoptry discharge in Toxoplasma.
Published in:
EMBO Journal, 2023, v. 42, n. 23, p. 1, doi. 10.15252/embj.2022113155
By:
- Valleau, Dylan;
- Sidik, Saima M;
- Godoy, Luiz C;
- Acevedo‐Sánchez, Yamilex;
- Pasaje, Charisse Flerida A;
- Huynh, My‐Hang;
- Carruthers, Vern B;
- Niles, Jacquin C;
- Lourido, Sebastian
Publication type:
Article
Contribution of the OBSCN Nonsynonymous Variants to Aspirin Exacerbated Respiratory Disease Susceptibility in Korean Population.
Published in:
DNA & Cell Biology, 2012, v. 31, n. 6, p. 1001, doi. 10.1089/dna.2011.1436
By:
- Kim, Jeong-Hyun;
- Park, Byung-Lae;
- Pasaje, Charisse Flerida A.;
- Kim, Yongha;
- Bae, Joon Seol;
- Park, Jong Sook;
- Uh, Soo-Taek;
- Kim, Yong-Hoon;
- Kim, Mi-Kyeong;
- Choi, Inseon S.;
- Cho, Sang Heon;
- Choi, Byoung Whui;
- Koh, InSong;
- Park, Choon-Sik;
- Shin, Hyoung Doo
Publication type:
Article
Positive Association between Aspirin-Intolerant Asthma and Genetic Polymorphisms of FSIP1: a Case-Case Study.
Published in:
BMC Pulmonary Medicine, 2010, v. 10, p. 34, doi. 10.1186/1471-2466-10-34
By:
- Jason Yongha Kim;
- Jeong Hyun Kim;
- Tae Joon Park;
- Joon Seol Bae;
- Jin Sol Lee;
- Pasaje, Charisse Flerida;
- Byung Lae Park;
- Hyun Sub Cheong;
- Jong-Sook Park;
- Sung-Woo Park;
- Soo-Taek Uh;
- Mi-Kyeong Kim;
- Choi, Inseon S.;
- Sang Heon Cho;
- Byoung Whui Choi;
- Choon-Sik Park;
- Hyoung Doo Shin
Publication type:
Article
TGFBR3 Polymorphisms and Its Haplotypes Associated with Chronic Hepatitis B Virus Infection and Age of Hepatocellular Carcinoma Occurrence.
Published in:
Digestive Diseases, 2011, v. 29, n. 3, p. 278, doi. 10.1159/000327559
By:
- Kim, Jeong-Hyun;
- Yu, Su Jong;
- Park, Byung-Lae;
- Cheong, Hyun Sub;
- Pasaje, Charisse Flerida A.;
- Bae, Joon Seol;
- Lee, Hyo-Suk;
- Shin, Hyoung Doo;
- Kim, Yoon Jun
Publication type:
Article
No associations of polymorphisms in ADPRT with hepatitis B virus clearance and hepatocellular carcinoma occurrence in a Korean population.
Published in:
Hepatology Research, 2011, v. 41, n. 3, p. 250, doi. 10.1111/j.1872-034X.2010.00772.x
By:
- Lee, Jin Sol;
- Kim, Jeong-Hyun;
- Park, Byung-Lae;
- Cheong, Hyun Sub;
- Koh, InSong;
- Kim, Jason Yong-ha;
- Park, Tae Joon;
- Pasaje, Charisse Flerida;
- Bae, Joon Seol;
- Lee, Hyo-Suk;
- Kim, Yoon Jun;
- Shin, Hyoung Doo
Publication type:
Article
Selective inhibition of apicoplast tryptophanyl-tRNA synthetase causes delayed death in Plasmodium falciparum.
Published in:
Scientific Reports, 2016, p. 27531, doi. 10.1038/srep27531
By:
- Pasaje, Charisse Flerida A.;
- Cheung, Vanessa;
- Kennedy, Kit;
- Lim, Erin E.;
- Baell, Jonathan B.;
- Griffin, Michael D. W.;
- Ralph, Stuart A.
Publication type:
Article
Loss of ATF2 Function Leads to Cranial Motoneuron Degeneration during Embryonic Mouse Development.
Published in:
PLoS ONE, 2011, v. 6, n. 4, p. 1, doi. 10.1371/journal.pone.0019091
By:
- Joon Seol Bae;
- Hyun Sub Cheong;
- Ji-Hong Kim;
- Byung Lae Park;
- Jeong-Hyun Kim;
- Tae Joon Park;
- Jason Yongha Kim;
- Pasaje, Charisse Flerida A.;
- Jin Sol Lee;
- Yun-Ju Park;
- Miey Park;
- Chan Park;
- InSong Koh;
- Yeun-Jun Chung;
- Jong-Young Lee;
- Hyoung Doo Shin
Publication type:
Article
The Genetic Effect of Copy Number Variations on the Risk of Type 2 Diabetes in a Korean Population.
Published in:
PLoS ONE, 2011, v. 6, n. 4, p. 1, doi. 10.1371/journal.pone.0019091
By:
- Joon Seol Bae;
- Hyun Sub Cheong;
- Ji-Hong Kim;
- Byung Lae Park;
- Jeong-Hyun Kim;
- Tae Joon Park;
- Jason Yongha Kim;
- Pasaje, Charisse Flerida A.;
- Jin Sol Lee;
- Yun-Ju Park;
- Miey Park;
- Chan Park;
- InSong Koh;
- Yeun-Jun Chung;
- Jong-Young Lee;
- Hyoung Doo Shin
Publication type:
Article
Genome-Wide Profiling of Structural Genomic Variations in Korean HapMap Individuals.
Published in:
PLoS ONE, 2010, v. 5, n. 7, p. 1, doi. 10.1371/journal.pone.0011417
By:
- Bae, Joon Seol;
- Cheong, Hyun Sub;
- Park, Byung Lae;
- Kim, Lyoung Hyo;
- Han, Chang Soo;
- Park, Tae Joon;
- Kim, Jason Yongha;
- Pasaje, Charisse Flerida A.;
- Lee, Jin Sol;
- Shin, Hyoung Doo
Publication type:
Article
Possible Association of SLC22A2 Polymorphisms with Aspirin-Intolerant Asthma.
Published in:
International Archives of Allergy & Immunology, 2011, v. 155, n. 4, p. 395, doi. 10.1159/000321267
By:
- Park, Tae-Joon;
- Kim, Jeong-Hyun;
- Bae, Joon-Seol;
- Park, Byung-Lae;
- Cheong, Hyun Sub;
- Chun, Ji-Yong;
- Lee, Jin-Sol;
- Kim, Jason Yongha;
- Pasaje, Charisse Flerida;
- Cho, Sang Heon;
- Uh, Soo-Taek;
- Kim, Mi-Kyeong;
- Choi, Inseon S.;
- Koh, In Song;
- Park, Choon-Sik;
- Shin, Hyoung Doo
Publication type:
Article
Association of SLC6A12 variants with aspirin-intolerant asthma in a Korean population.
Published in:
Annals of Human Genetics, 2010, v. 74, n. 4, p. 326, doi. 10.1111/j.1469-1809.2010.00584.x
By:
- Pasaje, Charisse Flerida A.;
- Jeong-Hyun Kim;
- Byung-Lae Park;
- Hyun Sub Cheong;
- Ji-Yong Chun;
- Tae-Joon Park;
- Jin-Sol Lee;
- Yongha Kim;
- Joon Seol Bae;
- Jong Sook Park;
- Sang-Hyuk Yoon;
- Soo-Taek Uh;
- Jae-Sung Choi;
- Yong-Hoon Kim;
- Mi-Kyeong Kim;
- Choi, Inseon S.;
- Sang Heon Cho;
- Byoung Whui Choi;
- Choon-Sik Park;
- Hyoung Doo Shin
Publication type:
Article
Lack of association between PRNP M129V polymorphism and multiple sclerosis, mild cognitive impairment, alcoholism and schizophrenia in a Korean population.
Published in:
Disease Markers, 2010, v. 28, n. 5, p. 315, doi. 10.1155/2010/196538
By:
- Ihn-Geun Choi;
- Sung-Il Woo;
- Ho Jin Kim;
- Dai-Jin Kim;
- Byung Lae Park;
- Hyun Sub Cheong;
- Pasaje, Charisse Flerida A.;
- Tae Joon Park;
- Joon Seol Bae;
- Young Gyu Chai;
- Hyoung Doo Shin
Publication type:
Article
HLA-DRA polymorphisms associated with risk of nasal polyposis in asthmatic patients.
Published in:
American Journal of Rhinology & Allergy, 2012, v. 26, n. 1, p. 12, doi. 10.2500/ajra.2012.26.3692
By:
- Kim, Jeong-Hyun;
- Park, Byung-Lae;
- Cheong, Hyun Sub;
- Pasaje, Charisse Flerida A.;
- Bae, Joon Seol;
- Park, Jong Sook;
- Uh, Soo-Taek;
- Kim, Yong-Hoon;
- Kim, Mi-Kyeong;
- Choi, Inseon S.;
- Choi, Byoung Whui;
- Park, Choon-Sik;
- Shin, Hyoung Doo
Publication type:
Article
Genetic analysis of complement component 9 (C9) polymorphisms with clearance of hepatitis B virus infection.
Published in:
2011
By:
- Bae, Joon;
- Pasaje, Charisse;
- Park, Byung;
- Cheong, Hyun;
- Kim, Jeong-Hyun;
- Park, Tae;
- Kim, Jason;
- Lee, Jin;
- Koh, In;
- Lee, Hyo-Suk;
- Kim, Yoon;
- Shin, Hyoung;
- Bae, Joon Seol;
- Pasaje, Charisse Flerida A;
- Park, Byung Lae;
- Cheong, Hyun Sub;
- Park, Tae Joon;
- Kim, Jason Yongha;
- Lee, Jin Sol;
- Koh, In Song
Publication type:
journal article
An integrated platform for genome engineering and gene expression perturbation in Plasmodium falciparum.
Published in:
Scientific Reports, 2021, v. 11, n. 1, p. 1, doi. 10.1038/s41598-020-77644-4
By:
- Nasamu, Armiyaw S.;
- Falla, Alejandra;
- Pasaje, Charisse Flerida A.;
- Wall, Bridget A.;
- Wagner, Jeffrey C.;
- Ganesan, Suresh M.;
- Goldfless, Stephen J.;
- Niles, Jacquin C.
Publication type:
Article
Advances in malaria pharmacology and the online guide to MALARIA PHARMACOLOGY: IUPHAR review 38.
Published in:
British Journal of Pharmacology, 2023, v. 180, n. 15, p. 1899, doi. 10.1111/bph.16144
By:
- Armstrong, Jane F.;
- Campo, Brice;
- Alexander, Stephen P. H.;
- Arendse, Lauren B.;
- Cheng, Xiu;
- Davenport, Anthony P.;
- Faccenda, Elena;
- Fidock, David A.;
- Godinez‐Macias, Karla P.;
- Harding, Simon D.;
- Kato, Nobutaka;
- Lee, Marcus C. S.;
- Luth, Madeline R.;
- Mazitschek, Ralph;
- Mittal, Nimisha;
- Niles, Jacquin C.;
- Okombo, John;
- Ottilie, Sabine;
- Pasaje, Charisse Flerida A.;
- Probst, Alexandra S.
Publication type:
Article
Effect of Diffuse Panbronchiolitis Critical Region 1 Polymorphisms on the Risk of Aspirin-Exacerbated Respiratory Disease in Korean Asthmatics.
Published in:
Respiratory Care, 2012, v. 57, n. 5, p. 758, doi. 10.4187/respcare.01480
By:
- Lee, Jin Sol;
- Bae, Joon Seol;
- Kim, Jeong-Hyun;
- Kim, Jason Yongha;
- Park, Tae Joon;
- Pasaje, Charisse Flerida A.;
- Park, Byung-Lae;
- Cheong, Hyun Sub;
- Uh, Soo-Taek;
- Park, Jong-Sook;
- Park, Choon-Sik;
- Shin, Hyoung Doo
Publication type:
Article
Artemisinin kills malaria parasites by damaging proteins and inhibiting the proteasome.
Published in:
Nature Communications, 2018, v. 9, n. 1, p. 1, doi. 10.1038/s41467-018-06221-1
By:
- Bridgford, Jessica L.;
- Xie, Stanley C.;
- Cobbold, Simon A.;
- Pasaje, Charisse Flerida A.;
- Herrmann, Susann;
- Yang, Tuo;
- Gillett, David L.;
- Dick, Lawrence R.;
- Ralph, Stuart A.;
- Dogovski, Con;
- Spillman, Natalie J.;
- Tilley, Leann
Publication type:
Article
The anticancer human mTOR inhibitor sapanisertib potently inhibits multiple Plasmodium kinases and life cycle stages.
Published in:
Science Translational Medicine, 2022, v. 14, n. 667, p. 1, doi. 10.1126/scitranslmed.abo7219
By:
- Arendse, Lauren B.;
- Murithi, James M.;
- Qahash, Tarrick;
- Pasaje, Charisse Flerida A.;
- Godoy, Luiz C.;
- Dey, Sumanta;
- Gibhard, Liezl;
- Ghidelli-Disse, Sonja;
- Drewes, Gerard;
- Bantscheff, Marcus;
- Lafuente-Monasterio, Maria J.;
- Fienberg, Stephen;
- Wambua, Lynn;
- Gachuhi, Samuel;
- Coertzen, Dina;
- van der Watt, Mariëtte;
- Reader, Janette;
- Aswat, Ayesha S.;
- Erlank, Erica;
- Venter, Nelius
Publication type:
Article
The antimalarial MMV688533 provides potential for single-dose cures with a high barrier to Plasmodium falciparum parasite resistance.
Published in:
Science Translational Medicine, 2021, v. 13, n. 603, p. 1, doi. 10.1126/scitranslmed.abg6013
By:
- Murithi, James M.;
- Pascal, Cécile;
- Bath, Jade;
- Boulenc, Xavier;
- Gnädig, Nina F.;
- Pasaje, Charisse Flerida A.;
- Rubiano, Kelly;
- Yeo, Tomas;
- Mok, Sachel;
- Klieber, Sylvie;
- Desert, Paul;
- Jiménez-Díaz, María Belén;
- Marfurt, Jutta;
- Rouillier, Mélanie;
- Cherkaoui-Rbati, Mohammed H.;
- Gobeau, Nathalie;
- Wittlin, Sergio;
- Uhlemann, Anne-Catrin;
- Price, Ric N.;
- Wirjanata, Grennady
Publication type:
Article
Identification of copy number variations and common deletion polymorphisms in cattle.
Published in:
BMC Genomics, 2010, v. 11, p. 232, doi. 10.1186/1471-2164-11-232
By:
- Joon Seol Bae;
- Hyun Sub Cheong;
- Lyoung Hyo Kim;
- Suk NamGung;
- Tae Joon Park;
- Ji-Yong Chun;
- Jason Yongha Kim;
- Pasaje, Charisse Flerida A.;
- Jin Sol Lee;
- Hyoung Doo Shin
Publication type:
Article
Association of CACNG6 polymorphisms with aspirin-intolerance asthmatics in a Korean population.
Published in:
BMC Medical Genetics, 2010, v. 11, p. 138, doi. 10.1186/1471-2350-11-138
By:
- Jin Sol Lee;
- Jeong-Hyun Kim;
- Joon Seol Bae;
- Jason Yongha Kim;
- Tae Joon Park;
- Pasaje, Charisse Flerida;
- Byung-Lae Park;
- Hyun Sub Cheong;
- Soo-Taek Uh;
- Jong-Sook Park;
- An-Soo Jang;
- Mi-Kyeong Kim;
- Choi, Inseon S.;
- Choon-Sik Park;
- Hyoung Doo Shin
Publication type:
Article

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