Works by Parsons, Jason L.
Results: 44
Targeting Chk1 and Wee1 kinases enhances radiosensitivity of 2D and 3D head and neck cancer models to X-rays and low/high-LET protons.
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- Cell Death & Disease, 2025, v. 16, n. 1, p. 1, doi. 10.1038/s41419-025-07435-0
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- Article
Targeting OGG1 and PARG radiosensitises head and neck cancer cells to high-LET protons through complex DNA damage persistence.
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- Cell Death & Disease, 2024, v. 15, n. 2, p. 1, doi. 10.1038/s41419-024-06541-9
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- Article
DNA damage and repair dependencies of ionising radiation modalities.
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- Bioscience Reports, 2023, v. 43, n. 10, p. 1, doi. 10.1042/BSR20222586
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- Article
Current Insights into the Radiobiology of Boron Neutron Capture Therapy and the Potential for Further Improving Biological Effectiveness.
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- Cells (2073-4409), 2024, v. 13, n. 24, p. 2065, doi. 10.3390/cells13242065
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- Article
Targeting Acid Ceramidase to Improve the Radiosensitivity of Rectal Cancer.
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- Cells (2073-4409), 2020, v. 9, n. 12, p. 2693, doi. 10.3390/cells9122693
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- Article
The Biochemical Role of the Human NEIL1 and NEIL3 DNA Glycosylases on Model DNA Replication Forks.
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- Genes, 2019, v. 10, n. 4, p. 315, doi. 10.3390/genes10040315
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- Article
Autophagy is the main driver of radioresistance of HNSCC cells in mild hypoxia.
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- Journal of Cellular & Molecular Medicine, 2024, v. 28, n. 12, p. 1, doi. 10.1111/jcmm.18482
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- Article
Ubiquitin ligase ARF-BP1/Mule modulates base excision repair.
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- EMBO Journal, 2009, v. 28, n. 20, p. 3207, doi. 10.1038/emboj.2009.243
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- Article
NTH1 Is a New Target for Ubiquitylation-Dependent Regulation by TRIM26 Required for the Cellular Response to Oxidative Stress.
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- Molecular & Cellular Biology, 2018, v. 38, n. 12, p. 1, doi. 10.1128/MCB.00616-17
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- Article
Base Excision Repair, a Pathway Regulated by Posttranslational Modifications.
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- Molecular & Cellular Biology, 2016, v. 36, n. 10, p. 1426, doi. 10.1128/MCB.00030-16
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- Article
Cell death mechanisms in head and neck cancer cells in response to low and high-LET radiation.
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- Expert Reviews in Molecular Medicine, 2022, v. 24, p. 1, doi. 10.1017/erm.2021.31
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- Article
The radiobiology of HPV-positive and HPV-negative head and neck squamous cell carcinoma.
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- Expert Reviews in Molecular Medicine, 2020, v. 22, p. 1, doi. 10.1017/erm.2020.4
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- Article
Monitoring regulation of DNA repair activities of cultured cells in-gel using the comet assay.
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- Frontiers in Genetics, 2014, v. 5, p. 1, doi. 10.3389/fgene.2014.00232
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- Article
The Cellular Response to Complex DNA Damage Induced by Ionising Radiation.
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- International Journal of Molecular Sciences, 2023, v. 24, n. 5, p. 4920, doi. 10.3390/ijms24054920
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- Article
TRIM26 Maintains Cell Survival in Response to Oxidative Stress through Regulating DNA Glycosylase Stability.
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- International Journal of Molecular Sciences, 2022, v. 23, n. 19, p. 11613, doi. 10.3390/ijms231911613
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- Article
FLASH Radiotherapy: Current Knowledge and Future Insights Using Proton-Beam Therapy.
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- International Journal of Molecular Sciences, 2020, v. 21, n. 18, p. 6492, doi. 10.3390/ijms21186492
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- Article
Most DNA repair defects do not modify the relationship between relative biological effectiveness and linear energy transfer in CRISPR‐edited cells.
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- Medical Physics, 2024, v. 51, n. 1, p. 591, doi. 10.1002/mp.16764
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- Article
DNA polymerase δ-dependent repair of DNA single strand breaks containing 3′-end proximal lesions.
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- Nucleic Acids Research, 2007, v. 35, n. 4, p. 1054, doi. 10.1093/nar/gkl1115
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- Article
NEIL1 excises 3′ end proximal oxidative DNA lesions resistant to cleavage by NTH1 and OGG1.
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- Nucleic Acids Research, 2005, v. 33, n. 15, p. 4849, doi. 10.1093/nar/gki816
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- Article
Isolation of a small molecule inhibitor of DNA base excision repair.
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- Nucleic Acids Research, 2005, v. 33, n. 15, p. 4711, doi. 10.1093/nar/gki781
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- Article
APE1-dependent repair of DNA single-strand breaks containing 3′-end 8-oxoguanine.
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- Nucleic Acids Research, 2005, v. 33, n. 7, p. 2204, doi. 10.1093/nar/gki518
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- Article
APE1 is the major 3′-phosphoglycolate activity in human cell extracts.
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- Nucleic Acids Research, 2004, v. 32, n. 12, p. 3531, doi. 10.1093/nar/gkh676
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- Article
XRCC1–DNA polymerase β interaction is required for efficient base excision repair.
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- Nucleic Acids Research, 2004, v. 32, n. 8, p. 2550, doi. 10.1093/nar/gkh567
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- Article
microRNA‐184 is induced by store‐operated calcium entry and regulates early keratinocyte differentiation.
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- Journal of Cellular Physiology, 2020, v. 235, n. 10, p. 6854, doi. 10.1002/jcp.29579
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- Article
Inhibition of key DNA double strand break repair protein kinases enhances radiosensitivity of head and neck cancer cells to X-ray and proton irradiation.
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- Cell Death Discovery, 2024, v. 10, n. 1, p. 1, doi. 10.1038/s41420-024-02059-3
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- Article
Effectiveness of PARP inhibition in enhancing the radiosensitivity of 3D spheroids of head and neck squamous cell carcinoma.
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- Frontiers in Oncology, 2022, v. 12, p. 1, doi. 10.3389/fonc.2022.940377
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- Article
USP9X Is Required to Maintain Cell Survival in Response to High-LET Radiation.
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- Frontiers in Oncology, 2021, v. 11, p. 1, doi. 10.3389/fonc.2021.671431
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- Article
HDAC Inhibitors Can Enhance Radiosensitivity of Head and Neck Cancer Cells Through Suppressing DNA Repair.
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- Cancers, 2024, v. 16, n. 23, p. 4108, doi. 10.3390/cancers16234108
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- Article
The Potential for Targeting G 2 /M Cell Cycle Checkpoint Kinases in Enhancing the Efficacy of Radiotherapy.
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- Cancers, 2024, v. 16, n. 17, p. 3016, doi. 10.3390/cancers16173016
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- Article
Overcoming the Impact of Hypoxia in Driving Radiotherapy Resistance in Head and Neck Squamous Cell Carcinoma.
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- Cancers, 2022, v. 14, n. 17, p. 4130, doi. 10.3390/cancers14174130
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- Article
Targeting DNA Double-Strand Break Repair Enhances Radiosensitivity of HPV-Positive and HPV-Negative Head and Neck Squamous Cell Carcinoma to Photons and Protons.
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- Cancers, 2020, v. 12, n. 6, p. 1490, doi. 10.3390/cancers12061490
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- Article
Inhibition of ATM Increases the Radiosensitivity of Uveal Melanoma Cells to Photons and Protons.
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- Cancers, 2020, v. 12, n. 6, p. 1388, doi. 10.3390/cancers12061388
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- Article
The Radiobiological Effects of Proton Beam Therapy: Impact on DNA Damage and Repair.
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- Cancers, 2019, v. 11, n. 7, p. 946, doi. 10.3390/cancers11070946
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- Article
Base excision repair and its implications to cancer therapy.
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- Essays in Biochemistry, 2020, v. 64, n. 5, p. 831, doi. 10.1042/EBC20200013
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- Article
End-damage-specific proteins facilitate recruitment or stability of X-ray cross-complementing protein 1 at the sites of DNA single-strand break repair.
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- FEBS Journal, 2005, v. 272, n. 22, p. 5753, doi. 10.1111/j.1742-4658.2005.04962.x
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- Article
Poly(ADP-ribose) polymerase-1 protects excessive DNA strand breaks from deterioration during repair in human cell extracts.
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- FEBS Journal, 2005, v. 272, n. 8, p. 2012, doi. 10.1111/j.1742-4658.2005.04628.x
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- Article
HECTD1 promotes base excision repair in nucleosomes through chromatin remodelling.
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- Nucleic Acids Research, 2020, v. 48, n. 3, p. 1301, doi. 10.1093/nar/gkz1129
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- Article
Ubiquitylation-dependent regulation of NEIL1 by Mule and TRIM26 is required for the cellular DNA damage response.
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- Nucleic Acids Research, 2017, v. 45, n. 2, p. 726, doi. 10.1093/nar/gkw959
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- Article
ARF induction in response to DNA strand breaks is regulated by PARP1.
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- Nucleic Acids Research, 2014, v. 42, n. 4, p. 2320, doi. 10.1093/nar/gkt1185
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- Article
Phosphorylation of PNKP by ATM prevents its proteasomal degradation and enhances resistance to oxidative stress.
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- Nucleic Acids Research, 2012, v. 40, n. 22, p. 11404, doi. 10.1093/nar/gks909
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- Article
Ubiquitin ligase UBR3 regulates cellular levels of the essential DNA repair protein APE1 and is required for genome stability.
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- Nucleic Acids Research, 2012, v. 40, n. 2, p. 701, doi. 10.1093/nar/gkr744
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- Article
USP7/HAUSP stimulates repair of oxidative DNA lesions.
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- Nucleic Acids Research, 2011, v. 39, n. 7, p. 2604, doi. 10.1093/nar/gkq1210
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- Article
Impact of copper on the induction and repair of oxidative DNA damage, poly(ADP-ribosyl)ation and PARP-1 activity.
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- Molecular Nutrition & Food Research, 2007, v. 51, n. 2, p. 201, doi. 10.1002/mnfr.200600107
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- Article
Factors affecting the radiation response in glioblastoma.
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- Neuro-Oncology Advances, 2022, v. 4, n. 1, p. 1, doi. 10.1093/noajnl/vdac156
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- Article