Works by Park, Sang‐Youel

Results: 33

Antitumor Effects of Esculetin, a Natural Coumarin Derivative, against Canine Mammary Gland Tumor Cells by Inducing Cell Cycle Arrest and Apoptosis.

Published in:

Veterinary Sciences, 2023, v. 10, n. 2, p. 84, doi. 10.3390/vetsci10020084

By:

Choi, Jawun;
Yoo, Min-Jae;
Park, Sang-Youel;
Seol, Jae-Won

Publication type:

Article

Anti-cancer effect of palmatine through inhibition of the PI3K/AKT pathway in canine mammary gland tumor CMT-U27 cells.

Published in:

BMC Veterinary Research, 2023, v. 19, n. 1, p. 1, doi. 10.1186/s12917-023-03782-2

By:

Yoo, Min-Jae;
Choi, Jawun;
Jang, Ye-ji;
Park, Sang-Youel;
Seol, Jae-Won

Publication type:

Article

Inhibition of autophagy flux by sertraline attenuates TRAIL resistance in lung cancer via death receptor 5 upregulation.

Published in:

International Journal of Molecular Medicine, 2020, v. 46, n. 2, p. 795, doi. 10.3892/ijmm.2020.4635

By:

Zinnah, Kazi Mohammad Ali;
Seol, Jae-Won;
Park, Sang-Youel

Publication type:

Article

Downregulation of c-FLIP and upregulation of DR-5 by cantharidin sensitizes TRAIL-mediated apoptosis in prostate cancer cells via autophagy flux.

Published in:

International Journal of Molecular Medicine, 2020, v. 46, n. 1, p. 280, doi. 10.3892/ijmm.2020.4566

By:

Nazim, Uddin Md;
Yin, Honghua;
Park, Sang-Youel

Publication type:

Article

Attenuation of autophagy flux by 6-shogaol sensitizes human liver cancer cells to TRAIL-induced apoptosis via p53 and ROS.

Published in:

International Journal of Molecular Medicine, 2019, v. 43, n. 2, p. 701

By:

Nazim, Uddin MD.;
Park, Sang-Youel

Publication type:

Article

Sensitizing TRAIL-resistant A549 lung cancer cells and enhancing TRAIL-induced apoptosis with the antidepressant amitriptyline.

Published in:

Oncology Reports, 2021, v. 46, n. 1, p. N.PAG

By:

Zinnah, K.M.A.;
Park, Sang-Youel

Publication type:

Article

Neferine treatment enhances the TRAIL-induced apoptosis of human prostate cancer cells via autophagic flux and the JNK pathway.

Published in:

International Journal of Oncology, 2020, v. 56, n. 5, p. 1152, doi. 10.3892/ijo.2020.5012

By:

Nazim, Uddin Md;
Yin, Honghua;
Park, Sang-Youel

Publication type:

Article

Luteolin sensitizes human liver cancer cells to TRAIL-induced apoptosis via autophagy and JNK-mediated death receptor 5 upregulation.

Published in:

International Journal of Oncology, 2019, v. 54, n. 2, p. 665

By:

Nazim, Uddin Md.;
Park, Sang-Youel

Publication type:

Article

Gingerol-Induced Hypoxia-Inducible Factor 1 Alpha Inhibits Human Prion Peptide-Mediated Neurotoxicity.

Published in:

Phytotherapy Research, 2013, v. 27, n. 8, p. 1185, doi. 10.1002/ptr.4842

By:

Jeong, Jae‐Kyo;
Moon, Myung‐Hee;
Park, Yang‐Gyu;
Lee, Ju‐Hee;
Lee, You‐Jin;
Seol, Jae‐Won;
Park, Sang‐Youel

Publication type:

Article

Prion peptide-mediated calcium level alteration governs neuronal cell damage through AMPK-autophagy flux.

Published in:

Cell Communication & Signaling, 2020, v. 18, n. 1, p. 1, doi. 10.1186/s12964-020-00590-1

By:

Moon, Ji-Hong;
Park, Sang-Youel

Publication type:

Article

AMPK Activation Mediated by Hinokitiol Inhibits Adipogenic Differentiation of Mesenchymal Stem Cells through Autophagy Flux.

Published in:

International Journal of Endocrinology, 2018, p. 1, doi. 10.1155/2018/2014192

By:

Lee, Ju-Hee;
Jeong, Jae-Kyo;
Park, Sang-Youel

Publication type:

Article

CCL2, but not its receptor, is essential to restrict immune privileged central nervous system-invasion of Japanese encephalitis virus via regulating accumulation of CD11b+ Ly-6Chi monocytes.

Published in:

Immunology, 2016, v. 149, n. 2, p. 186, doi. 10.1111/imm.12626

By:

Kim, Jin Hyoung;
Patil, Ajit Mahadev;
Choi, Jin Young;
Kim, Seong Bum;
Uyangaa, Erdenebileg;
Hossain, Ferdaus Mohd Altaf;
Park, Sang‐Youel;
Lee, John Hwa;
Kim, Koanhoi;
Eo, Seong Kug

Publication type:

Article

Activated protein C (APC) can increase bone anabolism via a protease-activated receptor (PAR)1/2 dependent mechanism.

Published in:

Journal of Orthopaedic Research, 2014, v. 32, n. 12, p. 1549, doi. 10.1002/jor.22726

By:

Shen, Kaitlin;
Murphy, Ciara M.;
Chan, Ben;
Kolind, Mille;
Cheng, Tegan L.;
Mikulec, Kathy;
Peacock, Lauren;
Xue, Meilang;
Park, Sang‐Youel;
Little, David G.;
Jackson, Chris J.;
Schindeler, Aaron

Publication type:

Article

CCR5 ameliorates Japanese encephalitis via dictating the equilibrium of regulatory CD4(+)Foxp3(+) T and IL-17(+)CD4(+) Th17 cells.

Published in:

2016

By:

Jin Hyoung Kim;
Patil, Ajit Mahadev;
Jin Young Choi;
Seong Bum Kim;
Uyangaa, Erdenebelig;
Hossain, Ferdaus Mohd Altaf;
Sang-Youel Park;
John Hwa Lee;
Seong Kug Eo;
Kim, Jin Hyoung;
Choi, Jin Young;
Kim, Seong Bum;
Park, Sang-Youel;
Lee, John Hwa;
Eo, Seong Kug

Publication type:

journal article

Blockage of indoleamine 2,3-dioxygenase regulates Japanese encephalitis via enhancement of type I/II IFN innate and adaptive T-cell responses.

Published in:

2016

By:

Seong Bum Kim;
Jin Young Choi;
Erdenebileg Uyangaa;
Ajit Mahadev Patil;
Ferdaus Mohd Altaf Hossain;
Jin Hur;
Sang-Youel Park;
John-Hwa Lee;
Koanhoi Kim;
Seong Kug Eo;
Kim, Seong Bum;
Choi, Jin Young;
Uyangaa, Erdenebileg;
Patil, Ajit Mahadev;
Hossain, Ferdaus Mohd Altaf;
Hur, Jin;
Park, Sang-Youel;
Lee, John-Hwa;
Kim, Koanhoi;
Eo, Seong Kug

Publication type:

journal article

Amelioration of Japanese encephalitis by blockage of 4-1BB signaling is coupled to divergent enhancement of type I/II IFN responses and Ly-6C(hi) monocyte differentiation.

Published in:

2015

By:

Seong Bum Kim;
Jin Young Choi;
Jin Hyoung Kim;
Erdenebelig Uyangaa;
Patil, Ajit Mahadev;
Sang-Youel Park;
John Hwa Lee;
Koanhoi Kim;
Young Woo Han;
Seong Kug Eo;
Kim, Seong Bum;
Choi, Jin Young;
Kim, Jin Hyoung;
Uyangaa, Erdenebelig;
Park, Sang-Youel;
Lee, John Hwa;
Kim, Koanhoi;
Han, Young Woo;
Eo, Seong Kug

Publication type:

journal article

Cardiac glycoside sensitized hepatocellular carcinoma cells to TRAIL via ROS generation, p38MAPK, mitochondrial transition, and autophagy mediation.

Published in:

Molecular Carcinogenesis, 2019, v. 58, n. 11, p. 2040, doi. 10.1002/mc.23096

By:

Rasheduzzaman, Mohammad;
Yin, Honghua;
Park, Sang‐Youel

Publication type:

Article

Impaired Autophagic Flux by Citalopram Inhibits DR5 Degradation and Increases TRAIL‐Mediated Apoptosis.

Published in:

Journal of Clinical Pharmacy & Therapeutics, 2025, v. 2025, p. 1, doi. 10.1155/jcpt/7538839

By:

Zinnah, K. M. A.;
Munna, Ali Newaz;
Seol, Jae-Won;
Park, Sang-Youel;
Jiao, Peirong

Publication type:

Article

Synergistic Anti-Cancer Effects of ERB-041 and Genistein through Estrogen Receptor Suppression-Mediated PI3K/AKT Pathway Downregulation in Canine Mammary Gland Tumor Cells.

Published in:

International Journal of Molecular Sciences, 2024, v. 25, n. 5, p. 2466, doi. 10.3390/ijms25052466

By:

Yoo, Min-Jae;
Jang, Ye-Ji;
Park, Sang-Youel;
Choi, Ja-Wun;
Seol, Jae-Won

Publication type:

Article

Author Correction: Bisphosphonate enhances TRAIL sensitivity to human osteosarcoma cells via death receptor 5 upregulation.

Published in:

2018

By:

Moon, Myung-Hee;
Jeong, Jae-Kyo;
Seo, Jae-Suk;
Seol, Jae-Won;
Lee, You-Jin;
Xue, Meilang;
Jackson, Christopher J.;
Park, Sang-Youel

Publication type:

Correction Notice

Author Correction: Bisphosphonate enhances TRAIL sensitivity to human osteosarcoma cells via death receptor 5 upregulation.

Published in:

Experimental & Molecular Medicine EMM, 2018, v. 50, n. 8, p. 1, doi. 10.1038/s12276-018-0127-9

By:

Moon, Myung-Hee;
Jeong, Jae-Kyo;
Seo, Jae-Suk;
Seol, Jae-Won;
Lee, You-Jin;
Xue, Meilang;
Jackson, Christopher J.;
Park, Sang-Youel

Publication type:

Article

Inhibition of Autophagy by Captopril Attenuates Prion Peptide-Mediated Neuronal Apoptosis via AMPK Activation.

Published in:

Molecular Neurobiology, 2019, v. 56, n. 6, p. 4192, doi. 10.1007/s12035-018-1370-8

By:

Moon, Ji-Hong;
Jeong, Jae-Kyo;
Hong, Jeong-Min;
Seol, Jae-Won;
Park, Sang-Youel

Publication type:

Article

Optimizing autophagy modulation for enhanced TRAIL‐mediated therapy: Unveiling the superiority of late‐stage inhibition over early‐stage inhibition to overcome therapy resistance in cancer.

Published in:

Basic & Clinical Pharmacology & Toxicology, 2025, v. 136, n. 1, p. 1, doi. 10.1111/bcpt.14110

By:

Zinnah, Kazi Mohammad Ali;
Munna, Ali Newaz;
Park, Sang‐Youel

Publication type:

Article

CD11chi Dendritic Cells Regulate Ly-6Chi Monocyte Differentiation to Preserve Immune-privileged CNS in Lethal Neuroinflammation.

Published in:

Scientific Reports, 2015, v. 5, n. 1, p. 17548, doi. 10.1038/srep17548

By:

Kim, Jin Hyoung;
Choi, Jin Young;
Kim, Seong Bum;
Uyangaa, Erdenebelig;
Patil, Ajit Mahadev;
Han, Young Woo;
Park, Sang-Youel;
Lee, John Hwa;
Kim, Koanhoi;
Eo, Seong Kug

Publication type:

Article

Calcineurin Activation by Prion Protein Induces Neurotoxicity via Mitochondrial Reactive Oxygen Species.

Published in:

Oxidative Medicine & Cellular Longevity, 2021, p. 1, doi. 10.1155/2021/5572129

By:

Moon, Ji-Hong;
Hong, Jeong-Min;
Park, Sang-Youel

Publication type:

Article

Melatonin inhibits Japanese encephalitis virus replication and neurotoxicity via calcineurin-autophagy pathways.

Published in:

BMC Neuroscience, 2023, v. 24, n. 1, p. 1, doi. 10.1186/s12868-023-00832-1

By:

Moon, Ji-Hong;
Hong, Jeong-Min;
Seol, Jae-Won;
Park, Byung-Yong;
Eo, Seong Kug;
Park, Sang-Youel

Publication type:

Article

Endogenous MMP-9 and not MMP-2 promotes rheumatoid synovial fibroblast survival, inflammation and cartilage degradation.

Published in:

2014

By:

Xue, Meilang;
McKelvey, Kelly;
Shen, Kaitlin;
Minhas, Nikita;
March, Lyn;
Park, Sang-Youel;
Jackson, Christopher J.

Publication type:

Journal Article

Endogenous MMP-9 and not MMP-2 promotes rheumatoid synovial fibroblast survival, inflammation and cartilage degradation.

Published in:

Rheumatology, 2014, v. 53, n. 12, p. 2270, doi. 10.1093/rheumatology/keu254

By:

Xue, Meilang;
McKelvey, Kelly;
Shen, Kaitlin;
Minhas, Nikita;
March, Lyn;
Park, Sang-Youel;
Jackson, Christopher J.

Publication type:

Article

The antidiabetic drug troglitazone protects against PrP (106–126)-induced neurotoxicity via the PPARγ-autophagy pathway in neuronal cells.

Published in:

Molecular Medicine Reports, 2021, v. 23, n. 6, p. N.PAG, doi. 10.3892/mmr.2021.12069

By:

Moon, Ji-Hong;
Hong, Jeong-Min;
Park, Sang-Youel

Publication type:

Article

Autophagy flux inhibition mediated by celastrol sensitized lung cancer cells to TRAIL-induced apoptosis via regulation of mitochondrial transmembrane potential and reactive oxygen species.

Published in:

Molecular Medicine Reports, 2019, v. 19, n. 2, p. 984

By:

Nazim, Uddin Md;
Yin, Honghua;
Park, Sang-Youel

Publication type:

Article

Melatonin regulates the autophagic flux via activation of alpha-7 nicotinic acetylcholine receptors.

Published in:

Journal of Pineal Research, 2015, v. 59, n. 1, p. 24, doi. 10.1111/jpi.12235

By:

Jeong, Jae‐Kyo;
Park, Sang‐Youel

Publication type:

Article

Melatonin-mediated β-catenin activation protects neuron cells against prion protein-induced neurotoxicity.

Published in:

Journal of Pineal Research, 2014, v. 57, n. 4, p. 427, doi. 10.1111/jpi.12182

By:

Jeong, Jae‐Kyo;
Lee, Ju‐Hee;
Moon, Ji‐Hong;
Lee, You‐Jin;
Park, Sang‐Youel

Publication type:

Article

Melatonin-induced autophagy protects against human prion protein-mediated neurotoxicity.

Published in:

Journal of Pineal Research, 2012, v. 53, n. 2, p. 138, doi. 10.1111/j.1600-079X.2012.00980.x

By:

Jeong, Jae-Kyo;
Moon, Myung-Hee;
Lee, You-Jin;
Seol, Jae-Won;
Park, Sang-Youel

Publication type:

Article

Works by Park, Sang‐Youel

Antitumor Effects of Esculetin, a Natural Coumarin Derivative, against Canine Mammary Gland Tumor Cells by Inducing Cell Cycle Arrest and Apoptosis.

Anti-cancer effect of palmatine through inhibition of the PI3K/AKT pathway in canine mammary gland tumor CMT-U27 cells.

Inhibition of autophagy flux by sertraline attenuates TRAIL resistance in lung cancer via death receptor 5 upregulation.

Downregulation of c-FLIP and upregulation of DR-5 by cantharidin sensitizes TRAIL-mediated apoptosis in prostate cancer cells via autophagy flux.

Attenuation of autophagy flux by 6-shogaol sensitizes human liver cancer cells to TRAIL-induced apoptosis via p53 and ROS.

Sensitizing TRAIL-resistant A549 lung cancer cells and enhancing TRAIL-induced apoptosis with the antidepressant amitriptyline.

Neferine treatment enhances the TRAIL-induced apoptosis of human prostate cancer cells via autophagic flux and the JNK pathway.

Luteolin sensitizes human liver cancer cells to TRAIL-induced apoptosis via autophagy and JNK-mediated death receptor 5 upregulation.

Gingerol-Induced Hypoxia-Inducible Factor 1 Alpha Inhibits Human Prion Peptide-Mediated Neurotoxicity.

Prion peptide-mediated calcium level alteration governs neuronal cell damage through AMPK-autophagy flux.

AMPK Activation Mediated by Hinokitiol Inhibits Adipogenic Differentiation of Mesenchymal Stem Cells through Autophagy Flux.

CCL2, but not its receptor, is essential to restrict immune privileged central nervous system-invasion of Japanese encephalitis virus via regulating accumulation of CD11b<sup>+</sup> Ly-6C<sup>hi</sup> monocytes.

Activated protein C (APC) can increase bone anabolism via a protease-activated receptor (PAR)1/2 dependent mechanism.

CCR5 ameliorates Japanese encephalitis via dictating the equilibrium of regulatory CD4(+)Foxp3(+) T and IL-17(+)CD4(+) Th17 cells.

Blockage of indoleamine 2,3-dioxygenase regulates Japanese encephalitis via enhancement of type I/II IFN innate and adaptive T-cell responses.

Amelioration of Japanese encephalitis by blockage of 4-1BB signaling is coupled to divergent enhancement of type I/II IFN responses and Ly-6C(hi) monocyte differentiation.

Cardiac glycoside sensitized hepatocellular carcinoma cells to TRAIL via ROS generation, p38MAPK, mitochondrial transition, and autophagy mediation.

Impaired Autophagic Flux by Citalopram Inhibits DR5 Degradation and Increases TRAIL‐Mediated Apoptosis.

Synergistic Anti-Cancer Effects of ERB-041 and Genistein through Estrogen Receptor Suppression-Mediated PI3K/AKT Pathway Downregulation in Canine Mammary Gland Tumor Cells.

Author Correction: Bisphosphonate enhances TRAIL sensitivity to human osteosarcoma cells via death receptor 5 upregulation.

Author Correction: Bisphosphonate enhances TRAIL sensitivity to human osteosarcoma cells via death receptor 5 upregulation.

Inhibition of Autophagy by Captopril Attenuates Prion Peptide-Mediated Neuronal Apoptosis via AMPK Activation.

Optimizing autophagy modulation for enhanced TRAIL‐mediated therapy: Unveiling the superiority of late‐stage inhibition over early‐stage inhibition to overcome therapy resistance in cancer.

CD11c<sup>hi</sup> Dendritic Cells Regulate Ly-6C<sup>hi</sup> Monocyte Differentiation to Preserve Immune-privileged CNS in Lethal Neuroinflammation.

Calcineurin Activation by Prion Protein Induces Neurotoxicity via Mitochondrial Reactive Oxygen Species.

Melatonin inhibits Japanese encephalitis virus replication and neurotoxicity via calcineurin-autophagy pathways.

Endogenous MMP-9 and not MMP-2 promotes rheumatoid synovial fibroblast survival, inflammation and cartilage degradation.

Endogenous MMP-9 and not MMP-2 promotes rheumatoid synovial fibroblast survival, inflammation and cartilage degradation.

The antidiabetic drug troglitazone protects against PrP (106–126)-induced neurotoxicity via the PPARγ-autophagy pathway in neuronal cells.

Autophagy flux inhibition mediated by celastrol sensitized lung cancer cells to TRAIL-induced apoptosis via regulation of mitochondrial transmembrane potential and reactive oxygen species.

Melatonin regulates the autophagic flux via activation of alpha-7 nicotinic acetylcholine receptors.

Melatonin-mediated β-catenin activation protects neuron cells against prion protein-induced neurotoxicity.

Melatonin-induced autophagy protects against human prion protein-mediated neurotoxicity.