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A Biomarker-based Biological Age in UK Biobank: Composition and Prediction of Mortality and Hospital Admissions.
Published in:
2021
By:
- Chan, Mei Sum;
- Arnold, Matthew;
- Offer, Alison;
- Hammami, Imen;
- Mafham, Marion;
- Armitage, Jane;
- Perera, Rafael;
- Parish, Sarah
Publication type:
journal article
A genome-wide association study in Europeans and South Asians identifies five new loci for coronary artery disease.
Published in:
Nature Genetics, 2011, v. 43, n. 4, p. 339, doi. 10.1038/ng.782
By:
- Peden, John F;
- Hopewell, Jemma C;
- Saleheen, Danish;
- Chambers, John C;
- Hager, Jorg;
- Soranzo, Nicole;
- Collins, Rory;
- Danesh, John;
- Elliott, Paul;
- Farrall, Martin;
- Stirrups, Kathy;
- Zhang, Weihua;
- Hamsten, Anders;
- Parish, Sarah;
- Lathrop, Mark;
- Watkins, Hugh;
- Clarke, Robert;
- Deloukas, Panos;
- Kooner, Jaspal S;
- Goel, Anuj
Publication type:
Article
Common variants at 30 loci contribute to polygenic dyslipidemia.
Published in:
Nature Genetics, 2009, v. 41, n. 1, p. 56, doi. 10.1038/ng.291
By:
- Kathiresan, Sekar;
- Willer, Cristen J.;
- Peloso, Gina M;
- Demissie, Serkalem;
- Musunuru, Kiran;
- Schadt, Eric E.;
- Kaplan, Lee;
- Bennett, Derrick;
- Li, Yun;
- Tanaka, Toshiko;
- Voight, Benjamin F.;
- Bonnycastle, Lori L.;
- Jackson, Anne U.;
- Crawford, Gabriel;
- Surti, Aarti;
- Guiducci, Candace;
- Burtt, Noel P.;
- Parish, Sarah;
- Clarke, Robert;
- Zelenika, Diana
Publication type:
Article
A comprehensive analysis of APOE genotype effects on human brain structure in the UK Biobank.
Published in:
Translational Psychiatry, 2024, v. 14, n. 1, p. 1, doi. 10.1038/s41398-024-02848-5
By:
- Heise, Verena;
- Offer, Alison;
- Whiteley, William;
- Mackay, Clare E.;
- Armitage, Jane M.;
- Parish, Sarah
Publication type:
Article
Thromboxane biosynthesis and future events in diabetes: the ASCEND trial.
Published in:
European Heart Journal, 2024, v. 45, n. 15, p. 1355, doi. 10.1093/eurheartj/ehad868
By:
- Petrucci, Giovanna;
- Buck, Georgina A;
- Rocca, Bianca;
- Parish, Sarah;
- Baigent, Colin;
- Hatem, Duaa;
- Mafham, Marion;
- Habib, Aida;
- Bowman, Louise;
- Armitage, Jane;
- Patrono, Carlo
Publication type:
Article
Effects of aspirin on dementia and cognitive function in diabetic patients: the ASCEND trial.
Published in:
European Heart Journal, 2022, v. 43, n. 21, p. 2010, doi. 10.1093/eurheartj/ehac179
By:
- Parish, Sarah;
- Mafham, Marion;
- Offer, Alison;
- Barton, Jill;
- Wallendszus, Karl;
- Stevens, William;
- Buck, Georgina;
- Haynes, Richard;
- Collins, Rory;
- Bowman, Louise;
- Armitage, Jane
Publication type:
Article
Independent risk factors for simvastatin-related myopathy and relevance to different types of muscle symptom.
Published in:
European Heart Journal, 2020, v. 41, n. 35, p. 3336, doi. 10.1093/eurheartj/ehaa574
By:
- Hopewell, Jemma C;
- Offer, Alison;
- Haynes, Richard;
- Bowman, Louise;
- Li, Jing;
- Chen, Fang;
- Bulbulia, Richard;
- Lathrop, Mark;
- Baigent, Colin;
- Landray, Martin J;
- Collins, Rory;
- Armitage, Jane;
- Parish, Sarah
Publication type:
Article
Comparison of the Accuracy and Completeness of Records of Serious Vascular Events in Routinely Collected Data vs Clinical Trial–Adjudicated Direct Follow-up Data in the UK: Secondary Analysis of the ASCEND Randomized Clinical Trial.
Published in:
JAMA Network Open, 2021, v. 4, n. 12, p. e2139748, doi. 10.1001/jamanetworkopen.2021.39748
By:
- Harper, Charlie;
- Mafham, Marion;
- Herrington, William;
- Staplin, Natalie;
- Stevens, William;
- Wallendszus, Karl;
- Haynes, Richard;
- Landray, Martin J.;
- Parish, Sarah;
- Bowman, Louise;
- Armitage, Jane
Publication type:
Article
The exon 1–8C/G SNP in the PSMA6 gene contributes only a small amount to the burden of myocardial infarction in 6946 cases and 2720 controls from a United Kingdom population.
Published in:
European Journal of Human Genetics, 2008, v. 16, n. 4, p. 480, doi. 10.1038/sj.ejhg.5201948
By:
- Bennett, Derrick A.;
- Peng Xu;
- Clarke, Robert;
- Zondervan, Krina;
- Parish, Sarah;
- Palmer, Alison;
- Cardon, Lon;
- Peto, Richard;
- Lathrop, Mark;
- Collins, Rory
Publication type:
Article
The joint effects of apolipoprotein B, apolipoprotein A1, LDL cholesterol, and HDL cholesterol on risk: 3510 cases of acute myocardial infarction and 9805 controls†.
Published in:
European Heart Journal, 2009, v. 30, n. 17, p. 2137
By:
- Parish, Sarah;
- Peto, Richard;
- Palmer, Alison;
- Clarke, Robert;
- Lewington, Sarah;
- Offer, Alison;
- Whitlock, Gary;
- Clark, Sarah;
- Youngman, Linda;
- Sleight, Peter;
- Collins, Rory
Publication type:
Article
Effects of homocysteine-lowering with folic acid plus vitamin B12 vs placebo on mortality and major morbidity in myocardial infarction survivors: a randomized trial.
Published in:
2010
By:
- Armitage JM;
- Bowman L;
- Clarke RJ;
- Wallendszus K;
- Bulbulia R;
- Rahimi K;
- Haynes R;
- Parish S;
- Sleight P;
- Peto R;
- Collins R;
- Study of the Effectiveness of Additional Reductions in Cholesterol and Homocysteine (SEARCH) Collaborative Group;
- Armitage, Jane M;
- Bowman, Louise;
- Clarke, Robert J;
- Wallendszus, Karl;
- Bulbulia, Richard;
- Rahimi, Kazem;
- Haynes, Richard;
- Parish, Sarah
Publication type:
journal article
Effect of low-dose aspirin on urinary 11-dehydro-thromboxane B2 in the ASCEND (A Study of Cardiovascular Events iN Diabetes) randomized controlled trial.
Published in:
Trials, 2023, v. 24, n. 1, p. 1, doi. 10.1186/s13063-023-07198-z
By:
- Parish, Sarah;
- Buck, Georgina;
- Aung, Theingi;
- Mafham, Marion;
- Clark, Sarah;
- Hill, Michael R.;
- Collins, Rory;
- Bowman, Louise;
- Armitage, Jane
Publication type:
Article
Gender differences in modifiable risk factors for hip fracture: 10‐year follow‐up of a prospective study of 0.5 million Chinese adults.
Published in:
Journal of Internal Medicine, 2022, v. 291, n. 4, p. 481, doi. 10.1111/joim.13429
By:
- Yao, Pang;
- Parish, Sarah;
- Bennett, Derrick A.;
- Du, Huaidong;
- Yang, Ling;
- Chen, Yiping;
- Guo, Yu;
- Yu, Canqing;
- Zhou, Gang;
- Lv, Jun;
- Li, Liming;
- Chen, Zhengming;
- Clarke, Robert
Publication type:
Article
Genetic associations of adult height with risk of cardioembolic and other subtypes of ischemic stroke: A mendelian randomization study in multiple ancestries.
Published in:
PLoS Medicine, 2022, v. 19, n. 4, p. 1, doi. 10.1371/journal.pmed.1003967
By:
- Linden, Andrew B.;
- Clarke, Robert;
- Hammami, Imen;
- Hopewell, Jemma C.;
- Guo, Yu;
- Whiteley, William N.;
- Lin, Kuang;
- Turnbull, Iain;
- Chen, Yiping;
- Yu, Canqing;
- Lv, Jun;
- Offer, Alison;
- Bennett, Derrick;
- Walters, Robin G.;
- Li, Liming;
- Chen, Zhengming;
- Parish, Sarah
Publication type:
Article
Genetic associations of adult height with risk of cardioembolic and other subtypes of ischemic stroke: A mendelian randomization study in multiple ancestries.
Published in:
2022
By:
- Linden, Andrew B;
- Clarke, Robert;
- Hammami, Imen;
- Hopewell, Jemma C;
- Guo, Yu;
- Whiteley, William N;
- Lin, Kuang;
- Turnbull, Iain;
- Chen, Yiping;
- Yu, Canqing;
- Lv, Jun;
- Offer, Alison;
- Bennett, Derrick;
- Walters, Robin G;
- Li, Liming;
- Chen, Zhengming;
- Parish, Sarah;
- China Kadoorie Biobank Collaborative Group
Publication type:
journal article
Assessment of the Role of Carotid Atherosclerosis in the Association Between Major Cardiovascular Risk Factors and Ischemic Stroke Subtypes.
Published in:
JAMA Network Open, 2019, v. 2, n. 5, p. e194873, doi. 10.1001/jamanetworkopen.2019.4873
By:
- Parish, Sarah;
- Arnold, Matthew;
- Clarke, Robert;
- Du, Huaidong;
- Wan, Eric;
- Kurmi, Om;
- Chen, Yiping;
- Guo, Yu;
- Bian, Zheng;
- Collins, Rory;
- Li, Liming;
- Chen, Zhengming
Publication type:
Article
Assessement of Vascular Event Prevention and Cognitive Function Among Older Adults With Preexisting Vascular Disease or Diabetes: A Secondary Analysis of 3 Randomized Clinical Trials.
Published in:
JAMA Network Open, 2019, v. 2, n. 3, p. e190223, doi. 10.1001/jamanetworkopen.2019.0223
By:
- Offer, Alison;
- Arnold, Matthew;
- Clarke, Robert;
- Bennett, Derrick;
- Bowman, Louise;
- Bulbulia, Richard;
- Haynes, Richard;
- Li, Jing;
- Hopewell, Jemma C.;
- Landray, Martin;
- Armitage, Jane;
- Collins, Rory;
- Parish, Sarah
Publication type:
Article
Burden of carotid artery atherosclerosis in Chinese adults: Implications for future risk of cardiovascular diseases.
Published in:
European Journal of Preventive Cardiology, 2017, v. 24, n. 6, p. 647, doi. 10.1177/2047487317689973
By:
- Clarke, Robert;
- Du, Huaidong;
- Kurmi, Om;
- Parish, Sarah;
- Yang, Meng;
- Arnold, Matthew;
- Guo, Yu;
- Bian, Zheng;
- Wang, Liang;
- Chen, Yuexin;
- Meijer, Rudy;
- Sansome, Sam;
- McDonnell, John;
- Collins, Rory;
- Li, Liming;
- Chen, Zhengming
Publication type:
Article
Carotid Intima-Media Thickness but Not Carotid Artery Plaque in Healthy Individuals Is Linked to Lean Body Mass.
Published in:
2019
By:
- Arnold, Matthew;
- Linden, Andrew;
- Clarke, Robert;
- Yu Guo;
- Huaidong Du;
- Zheng Bian;
- Wan, Eric;
- Meng Yang;
- Liang Wang;
- Yuexin Chen;
- Jianwei Chen;
- Huajun Long;
- Qijun Gu;
- Collins, Rory;
- Liming Li;
- Zhengming Chen;
- Parish, Sarah;
- Guo, Yu;
- Du, Huaidong;
- Bian, Zheng
Publication type:
journal article
A statin-dependent QTL for GATM expression is associated with statin-induced myopathy.
Published in:
Nature, 2013, v. 502, n. 7471, p. 377, doi. 10.1038/nature12508
By:
- Mangravite, Lara M.;
- Engelhardt, Barbara E.;
- Medina, Marisa W.;
- Smith, Joshua D.;
- Brown, Christopher D.;
- Chasman, Daniel I.;
- Mecham, Brigham H.;
- Howie, Bryan;
- Shim, Heejung;
- Naidoo, Devesh;
- Feng, QiPing;
- Rieder, Mark J.;
- Chen, Yii.-Der I.;
- Rotter, Jerome I.;
- Ridker, Paul M.;
- Hopewell, Jemma C.;
- Parish, Sarah;
- Armitage, Jane;
- Collins, Rory;
- Wilke, Russell A.
Publication type:
Article
Weight loss in a cardiovascular trial population identifies people at future risk of dementia.
Published in:
Alzheimer's & Dementia: Diagnosis, Assessment & Disease Monitoring, 2022, v. 14, n. 1, p. 1, doi. 10.1002/dad2.12352
By:
- van der Veere, Pieter;
- Hammami, Imen;
- Buck, Georgina;
- Greenland, Melanie;
- Offer, Alison;
- Nunn, Michelle;
- Whiteley, William;
- Bulbulia, Richard;
- Collins, Rory;
- Armitage, Jane;
- Mafham, Marion;
- Parish, Sarah
Publication type:
Article
Investigating modifications to participant information materials to improve recruitment into a large randomized trial.
Published in:
2019
By:
- The HPS2-THRIVE Collaborative Group;
- Haynes, Richard;
- Chen, Fang;
- Wincott, Elizabeth;
- Dayanandan, Rejive;
- Lay, Michael J.;
- Parish, Sarah;
- Bowman, Louise;
- Landray, Martin J.;
- Armitage, Jane;
- Collins, R.;
- Baigent, C.;
- Chen, Z.;
- Chen, Y.;
- Jiang, L.;
- Pedersen, T.;
- Rahimi, K.;
- Tobert, J.;
- Sleight, P.;
- Simpson, D.
Publication type:
journal article
Lymphotoxin-α Gene and Risk of Myocardial Infarction in 6,928 Cases and 2,712 Controls in the ISIS Case-Control Study.
Published in:
PLoS Genetics, 2006, v. 3, n. 1, p. e107, doi. 10.1371/journal.pgen.0020107
By:
- Clarke, Robert;
- Peng Xu;
- Bennett, Derrick;
- Lewington, Sarah;
- Zondervan, Krina;
- Parish, Sarah;
- Palmer, Alison;
- Clark, Sarah;
- Cardon, Lon;
- Peto, Richard;
- Lathrop, Mark;
- Collins, Rory
Publication type:
Article
Association of vitamin D with risk of type 2 diabetes: A Mendelian randomisation study in European and Chinese adults.
Published in:
2018
By:
- Lu, Ling;
- Bennett, Derrick A.;
- Millwood, Iona Y.;
- Parish, Sarah;
- McCarthy, Mark I.;
- Mahajan, Anubha;
- Lin, Xu;
- Bragg, Fiona;
- Guo, Yu;
- Holmes, Michael V.;
- Afzal, Shoaib;
- Nordestgaard, Børge G.;
- Bian, Zheng;
- Hill, Michael;
- Walters, Robin G.;
- Li, Liming;
- Chen, Zhengming;
- Clarke, Robert
Publication type:
journal article
Accuracy of heart failure ascertainment using routinely collected healthcare data: a systematic review and meta-analysis.
Published in:
Systematic Reviews, 2024, v. 13, n. 1, p. 1, doi. 10.1186/s13643-024-02477-5
By:
- Goonasekera, Michelle. A.;
- Offer, Alison;
- Karsan, Waseem;
- El-Nayir, Muram;
- Mallorie, Amy E.;
- Parish, Sarah;
- Haynes, Richard J.;
- Mafham, Marion M.
Publication type:
Article
Conventional and genetic associations of BMI with major vascular and non-vascular disease incidence and mortality in a relatively lean Chinese population: U-shaped relationship revisited.
Published in:
International Journal of Epidemiology, 2024, v. 53, n. 5, p. 1, doi. 10.1093/ije/dyae125
By:
- Iona, Andri;
- Bragg, Fiona;
- Fairhurst-Hunter, Zammy;
- Millwood, Iona Y;
- Wright, Neil;
- Lin, Kuang;
- Yang, Ling;
- Du, Huaidong;
- Chen, Yiping;
- Pei, Pei;
- Cheng, Liang;
- Schmidt, Dan;
- Avery, Daniel;
- Yu, Canqing;
- Lv, Jun;
- Clarke, Robert;
- Walters, Robin;
- Li, Liming;
- Parish, Sarah;
- Chen, Zhengming
Publication type:
Article
MTHFR and risk of stroke and heart disease in a low-folate population: a prospective study of 156 000 Chinese adults.
Published in:
International Journal of Epidemiology, 2023, v. 52, n. 6, p. 1862, doi. 10.1093/ije/dyad147
By:
- Bennett, Derrick A;
- Parish, Sarah;
- Millwood, Iona Y;
- Guo, Yu;
- Chen, Yiping;
- Turnbull, Iain;
- Yang, Ling;
- Lv, Jun;
- Yu, Canqing;
- Smith, George Davey;
- Wang, Yongjun;
- Wang, Yilong;
- Peto, Richard;
- Collins, Rory;
- Walters, Robin G;
- Li, Liming;
- Chen, Zhengming;
- Clarke, Robert;
- Group, the China Kadoorie Biobank (CKB) Study Collaborative
Publication type:
Article
Independent effects of adiposity measures on risk of atrial fibrillation in men and women: a study of 0.5 million individuals.
Published in:
2022
By:
- Camm, C Fielder;
- Lacey, Ben;
- Massa, M Sofia;
- Ende, Adam Von;
- Gajendragadkar, Parag;
- Stiby, Alexander;
- Valdes-Marquez, Elsa;
- Lewington, Sarah;
- Wijesurendra, Rohan;
- Parish, Sarah;
- Casadei, Barbara;
- Hopewell, Jemma C;
- Von Ende, Adam
Publication type:
journal article
A phenome-wide association study of a lipoprotein-associated phospholipase A2 loss-of-function variant in 90 000 Chinese adults.
Published in:
2016
By:
- Millwood, Iona Y.;
- Bennett, Derrick A.;
- Walters, Robin G.;
- Clarke, Robert;
- Waterworth, Dawn;
- Johnson, Toby;
- Yiping Chen;
- Ling Yang;
- Yu Guo;
- Zheng Bian;
- Hacker, Alex;
- Yeo, Astrid;
- Parish, Sarah;
- Hill, Michael R.;
- Chissoe, Stephanie;
- Peto, Richard;
- Cardon, Lon;
- Collins, Rory;
- Liming Li;
- Zhengming Chen
Publication type:
journal article
Fibrinogen and coronary heart disease: test of causality by ‘Mendelian randomization’.
Published in:
International Journal of Epidemiology, 2006, v. 35, n. 4, p. 935, doi. 10.1093/ije/dyl114
By:
- Bernard Keavney;
- John Danesh;
- Sarah Parish;
- Alison Palmer;
- Sarah Clark;
- Linda Youngman;
- Marc Delépine;
- Mark Lathrop;
- Richard Peto;
- Rory Collins
Publication type:
Article
Lipid-related genes and myocardial infarction in 4685 cases and 3460 controls: discrepancies between genotype, blood lipid concentrations, and coronary disease risk.
Published in:
International Journal of Epidemiology, 2004, v. 33, n. 5, p. 1002, doi. 10.1093/ije/dyh275
By:
- Bernard Keavney;
- Alison Palmer;
- Sarah Parish;
- Sarah Clark;
- Linda Youngman;
- John Danesh;
- Colin McKenzie;
- Marc Delépine;
- Mark Lathrop;
- Richard Peto;
- Rory Collins
Publication type:
Article
Effect of temperature and light on the stability of fat-soluble vitamins in whole blood over several days: implications for epidemiological studies.
Published in:
International Journal of Epidemiology, 2004, v. 33, n. 3, p. 518, doi. 10.1093/ije/dyh064
By:
- Sarah Clark;
- Linda D Youngman;
- Buki Chukwurah;
- Alison Palmer;
- Sarah Parish;
- Richard Peto;
- Rory Collins
Publication type:
Article
Stability of plasma analytes after delayed separation of whole blood: implications for epidemiological studies.
Published in:
2003
By:
- Clark, Sarah;
- Youngman, Linda D;
- Palmer, Alison;
- Parish, Sarah;
- Peto, Richard;
- Collins, Rory
Publication type:
journal article
Impact of common genetic variation on response to simvastatin therapy among 18 705 participants in the Heart Protection Study.
Published in:
European Heart Journal, 2013, v. 34, n. 13, p. 982
By:
- Hopewell, Jemma C.;
- Parish, Sarah;
- Offer, Alison;
- Link, Emma;
- Clarke, Robert;
- Lathrop, Mark;
- Armitage, Jane;
- Collins, Rory
Publication type:
Article
Homocysteine and Coronary Heart Disease: Meta-analysis of MTHFR Case-Control Studies, Avoiding Publication Bias.
Published in:
PLoS Medicine, 2012, v. 9, n. 2, p. 1
By:
- Clarke, Robert;
- Bennett, Derrick A.;
- Parish, Sarah;
- Verhoef, Petra;
- Dötsch-Klerk, Mariska;
- Lathrop, Mark;
- Xu, Peng;
- Nordestgaard, Børge G.;
- Holm, Hilma;
- Hopewell, Jemma C.;
- Saleheen, Danish;
- Tanaka, Toshihiro;
- Anand, Sonia S.;
- Chambers, John C.;
- Kleber, Marcus E.;
- Ouwehand, Willem H.;
- Yamada, Yoshiji;
- Elbers, Clara;
- Peters, Bas;
- Stewart, Alexandre F. R.
Publication type:
Article

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