Works matching AU Parchment, Ralph E.

Results: 26

PARP Inhibitor Applicability: Detailed Assays for Homologous Recombination Repair Pathway Components.

Published in:

OncoTargets & Therapy, 2022, v. 15, p. 165, doi. 10.2147/OTT.S278092

By:

Coyne, Geraldine O'Sullivan;
Karlovich, Chris;
Wilsker, Deborah;
Voth, Andrea Regier;
Parchment, Ralph E;
Chen, Alice P;
Doroshow, James H

Publication type:

Article

Novel antibody reagents for characterization of drug- and tumor microenvironment-induced changes in epithelial-mesenchymal transition and cancer stem cells.

Published in:

PLoS ONE, 2018, v. 13, n. 6, p. 1, doi. 10.1371/journal.pone.0199361

By:

Navas, Tony;
Pfister, Thomas D.;
Colantonio, Simona;
Aziz, Amina;
Dieckman, Lynda;
Saul, Richard G.;
Kaczmarczyk, Jan;
Borgel, Suzanne;
Alcoser, Sergio Y.;
Hollingshead, Melinda G.;
Lee, Young H.;
Bottaro, Donald P.;
Hiltke, Tara;
Whiteley, Gordon;
Takebe, Naoko;
Kinders, Robert J.;
Parchment, Ralph E.;
Tomaszewski, Joseph E.;
Doroshow, James H.

Publication type:

Article

Effects of amitriptyline and fluoxetine upon the in vitro proliferation of tumor cell lines.

Published in:

Journal of Experimental Therapeutics & Oncology, 2003, v. 3, n. 4, p. 169, doi. 10.1046/j.1359-4117.2003.01091.x

By:

Volpe, Donna A.;
Ellison, Christopher D.;
Parchment, Ralph E.;
Grieshaber, Charles K.;
Faustino, Patrick J.

Publication type:

Article

Development and Validation of an Immunoassay for Quantification of Topoisomerase I in Solid Tumor Tissues.

Published in:

PLoS ONE, 2012, v. 7, n. 12, p. 1, doi. 10.1371/journal.pone.0050494

By:

Pfister, Thomas D.;
Hollingshead, Melinda;
Kinders, Robert J.;
Zhang, Yiping;
Evrard, Yvonne A.;
Ji, Jiuping;
Khin, Sonny A.;
Borgel, Suzanne;
Stotler, Howard;
Carter, John;
Divelbiss, Raymond;
Kummar, Shivaani;
Pommier, Yves;
Parchment, Ralph E.;
Tomaszewski, Joseph E.;
Doroshow, James H.

Publication type:

Article

Modeling Pharmacodynamic Response to the Poly(ADPRibose) Polymerase Inhibitor ABT-888 in Human Peripheral Blood Mononuclear Cells.

Published in:

PLoS ONE, 2011, v. 6, n. 10, p. 1, doi. 10.1371/journal.pone.0026152

By:

Ji, Jiuping;
Kinders, Robert J.;
Zhang, Yiping;
Rubinstein, Larry;
Kummar, Shivaani;
Parchment, Ralph E.;
Tomaszewski, Joseph E.;
Doroshow, James H.

Publication type:

Article

Pharmacodynamic effects of the PARP inhibitor talazoparib (MDV3800, BMN 673) in patients with BRCA-mutated advanced solid tumors.

Published in:

Cancer Chemotherapy & Pharmacology, 2024, v. 93, n. 3, p. 177, doi. 10.1007/s00280-023-04600-0

By:

Mittra, Arjun;
Coyne, Geraldine H. O' Sullivan;
Zlott, Jennifer;
Kummar, Shivaani;
Meehan, Robert;
Rubinstein, Lawrence;
Juwara, Lamin;
Wilsker, Deborah;
Ji, Jiuping;
Miller, Brandon;
Navas, Tony;
Ferry-Galow, Katherine V.;
Voth, Andrea Regier;
Chang, Ting-Chia;
Jiwani, Shahanawaz;
Parchment, Ralph E.;
Doroshow, James H.;
Chen, Alice P.

Publication type:

Article

Intravenous 5-fluoro-2'-deoxycytidine administered with tetrahydrouridine increases the proportion of p16-expressing circulating tumor cells in patients with advanced solid tumors.

Published in:

2020

By:

Coyne, Geraldine O.'Sullivan;
Wang, Lihua;
Zlott, Jennifer;
Juwara, Lamin;
Covey, Joseph M.;
Beumer, Jan H.;
Cristea, Mihaela C.;
Newman, Edward M.;
Koehler, Stephen;
Nieva, Jorge J.;
Garcia, Agustin A.;
Gandara, David R.;
Miller, Brandon;
Khin, Sonny;
Miller, Sarah B.;
Steinberg, Seth M.;
Rubinstein, Larry;
Parchment, Ralph E.;
Kinders, Robert J.;
Piekarz, Richard L.

Publication type:

journal article

In vitro comparison of O4-benzylfolate modulated, BCNU-induced toxicity in human bone marrow using CFU-GM and tumor cell lines.

Published in:

2010

By:

Behrsing HP;
Furniss MJ;
Robillard KA;
Tomaszewski JE;
Parchment RE;
Behrsing, Holger Peter;
Furniss, Michael J;
Robillard, Kristine A;
Tomaszewski, Joseph E;
Parchment, Ralph E

Publication type:

journal article

In vitro comparison of O4-benzylfolate modulated, BCNU-induced toxicity in human bone marrow using CFU-GM and tumor cell lines.

Published in:

Cancer Chemotherapy & Pharmacology, 2010, v. 65, n. 6, p. 1083, doi. 10.1007/s00280-009-1113-7

By:

Behrsing, Holger Peter;
Furniss, Michael J.;
Robillard, Kristine A.;
Tomaszewski, Joseph E.;
Parchment, Ralph E.

Publication type:

Article

Metabolic profile of XK469 (2( R)-[4-(7-chloro-2-quinoxalinyl)oxyphenoxy]-propionic acid; NSC698215) in patients and in vitro: low potential for active or toxic metabolites or for drug–drug interactions.

Published in:

Cancer Chemotherapy & Pharmacology, 2005, v. 56, n. 4, p. 351, doi. 10.1007/s00280-004-0962-3

By:

Anderson, Lawrence W.;
Collins, Jerry M.;
Klecker, Raymond W.;
Katki, Aspandiar G.;
Parchment, Ralph E.;
Boinpally, Ramesh R.;
LoRusso, Patricia M.;
Ivy, S. Percy

Publication type:

Article

Bioavailability and pharmacokinetics of the investigational anticancer agent XK469 (NSC 698215) in rats following oral and intravenous administration.

Published in:

2005

By:

Boinpally, Ramesh;
Sen-Lin Zhou;
LoRusso, Patricia;
Parchment, Ralph;
Boinpally, Ramesh R;
Zhou, Sen-Lin;
LoRusso, Patricia M;
Parchment, Ralph E

Publication type:

journal article

In vitro and in vivo effects of acetyldinaline on murine megakaryocytopoiesis.

Published in:

2004

By:

Volpe, Donna A.;
LoRusso, Patricia M.;
Foster, Brenda J.;
Parchment, Ralph E.

Publication type:

journal article

Pharmacokinetics and tissue distribution of cryptophycin 52 (C-52) epoxide and cryptophycin 55 (C-55) chlorohydrin in mice with subcutaneous tumors.

Published in:

Cancer Chemotherapy & Pharmacology, 2003, v. 52, n. 1, p. 25, doi. 10.1007/s00280-003-0621-0

By:

Boinpally, Ramesh R.;
Polin, Lisa;
Zhou, Sen-Lin;
Jasti, Bhaskara R.;
Wiegand, Richard A.;
White, Kathryn;
Kushner, Juiwanna;
Horwitz, Jerome P.;
Corbett, Thomas H.;
Parchment, Ralph E.

Publication type:

Article

Antibody-independent capture of circulating tumor cells of non-epithelial origin with the ApoStream<sup>®</sup> system.

Published in:

PLoS ONE, 2017, v. 12, n. 4, p. 1, doi. 10.1371/journal.pone.0175414

By:

Balasubramanian, Priya;
Kinders, Robert J.;
Kummar, Shivaani;
Gupta, Vishal;
Hasegawa, David;
Menachery, Anoop;
Lawrence, Scott M.;
Wang, Lihua;
Ferry-Galow, Katherine;
Davis, Darren;
Parchment, Ralph E.;
Tomaszewski, Joseph E.;
Doroshow, James H.

Publication type:

Article

Phosphorylated fraction of H2AX as a measurement for DNA damage in cancer cells and potential applications of a novel assay.

Published in:

PLoS ONE, 2017, v. 12, n. 2, p. 1, doi. 10.1371/journal.pone.0171582

By:

Ji, Jiuping;
Zhang, Yiping;
Redon, Christophe E.;
Reinhold, William C.;
Chen, Alice P.;
Fogli, Laura K.;
Holbeck, Susan L.;
Parchment, Ralph E.;
Hollingshead, Melinda;
Tomaszewski, Joseph E.;
Dudon, Quentin;
Pommier, Yves;
Doroshow, James H.;
Bonner, William M.

Publication type:

Article

Roles for In Vitro Myelotoxicity Tests in Preclinical Drug Development and Clinical Trial Planning.

Published in:

Toxicologic Pathology, 1993, v. 21, n. 2, p. 241, doi. 10.1177/019262339302100217

By:

Parchment, Ralph E.;
Huang, Mau;
Erickson-Miller, Connie L.

Publication type:

Article

The statistics of phase 0 trials.

Published in:

Statistics in Medicine, 2010, v. 29, n. 10, p. 1072, doi. 10.1002/sim.3840

By:

Rubinstein, Larry V.;
Steinberg, Seth M.;
Kummar, Shivaani;
Kinders, Robert;
Parchment, Ralph E.;
Murgo, Anthony J.;
Tomaszewski, Joseph E.;
Doroshow, James H.

Publication type:

Article

In Vitro Human Tissue Models in Risk Assessment: Report of a Consensus-Building Workshop.

Published in:

Toxicological Sciences, 2001, v. 59, n. 1, p. 17, doi. 10.1093/toxsci/59.1.17

By:

MacGregor, James T.;
Collins, Jerry M.;
Sugiyama, Yuichi;
Tyson, Charles A.;
Dean, Jack;
Smith, Lewis;
Andersen, Melvin;
Curren, Rodger D.;
Houston, J. Brian;
Kadlubar, Fred F.;
Kedderis, Gregory L.;
Krishnan, Kannan;
Li, Albert P.;
Parchment, Ralph E.;
Thummel, Kenneth;
Tomaszewski, Joseph E.;
Ulrich, Roger;
Vickers, Alison E. M.;
Wrighton, Steven A.

Publication type:

Article

Compressing drug development timelines in oncology using phase '0' trials.

Published in:

2007

By:

Kummar, Shivaani;
Kinders, Robert;
Rubinstein, Larry;
Parchment, Ralph E.;
Murgo, Anthony J.;
Collins, Jerry;
Pickeral, Oxana;
Low, Jennifer;
Steinberg, Seth M.;
Gutierrez, Martin;
Yang, Sherry;
Helman, Lee;
Wiltrout, Robert;
Tomaszewski, Joseph E.;
Doroshow, James H.

Publication type:

review

Glycosyltransferases as probes for non-reducing terminal monosaccharide residues on nitrocellulose immobilized glycoproteins: The β (1-4) galactosyltransferase model.

Published in:

Electrophoresis, 1987, v. 8, n. 9, p. 421, doi. 10.1002/elps.1150080910

By:

Parchment, Ralph E.;
Shaper, Joel H.

Publication type:

Article

Loss of ubiquitin-specific peptidase 18 destabilizes 14-3-3ζ protein and represses lung cancer metastasis.

Published in:

Cancer Biology & Therapy, 2022, v. 23, n. 1, p. 265, doi. 10.1080/15384047.2022.2054242

By:

Chen, Zibo;
Zheng, Lin;
Chen, Yulong;
Liu, Xiuxia;
Kawakami, Masanori;
Mustachio, Lisa Maria;
Roszik, Jason;
Ferry-Galow, Katherine V.;
Parchment, Ralph E.;
Liu, Xin;
Andresson, Thorkell;
Duncan, Gerard;
Kurie, Jonathan M.;
Rodriguez-Canales, Jaime;
Liu, Xi;
Dmitrovsky, Ethan

Publication type:

Article

Combination therapy with pazopanib and tivantinib modulates VEGF and c-MET levels in refractory advanced solid tumors.

Published in:

Investigational New Drugs, 2021, v. 39, n. 6, p. 1577, doi. 10.1007/s10637-021-01138-x

By:

Kummar, Shivaani;
Srivastava, Apurva K.;
Navas, Tony;
Cecchi, Fabiola;
Lee, Young H.;
Bottaro, Donald P.;
Park, Sook Ryun;
Do, Khanh T.;
Jeong, Woondong;
Johnson, Barry C.;
Voth, Andrea R.;
Rubinstein, Larry;
Wright, John J.;
Parchment, Ralph E.;
Doroshow, James H.;
Chen, Alice P.

Publication type:

Article

Phase II trial of fenretinide in advanced renal carcinoma.

Published in:

Investigational New Drugs, 2005, v. 23, n. 2, p. 179, doi. 10.1007/s10637-005-5864-7

By:

Ulka Vaishampayan;
Lance K. Heilbrun;
Ralph E. Parchment;
Vikash Jain;
James Zwiebel;
Ramesh R. Boinpally;
Patricia LoRusso;
Maha Hussain

Publication type:

Article

In Vitro Exposure of Precision-Cut Lung Slices to 2-(4-Amino-3-Methylphenyl)-5-Fluorobenzothiazole Lysylamide Dihydrochloride (NSC 710305, Phortress) Increases Inflammatory Cytokine Content and Tissue Damage.

Published in:

Toxicological Sciences, 2013, v. 131, n. 2, p. 470, doi. 10.1093/toxsci/kfs319

By:

Behrsing, Holger P.;
Furniss, Michael J.;
Davis, Myrtle;
Tomaszewski, Joseph E.;
Parchment, Ralph E.

Publication type:

Article

In vivo-in vitro correlation of myelotoxicity of 9-methoxypyrazoloacridine (NSC-366140, PD115934)...

Published in:

JNCI: Journal of the National Cancer Institute, 1994, v. 86, n. 4, p. 273, doi. 10.1093/jnci/86.4.273

By:

Parchment, Ralph E.;
Volpe, Donna A.

Publication type:

Article

Association of changes in expression of HDAC and SIRT genes after drug treatment with cancer cell line sensitivity to kinase inhibitors.

Published in:

Epigenetics, 2024, v. 19, n. 1, p. 1, doi. 10.1080/15592294.2024.2309824

By:

Krushkal, Julia;
Zhao, Yingdong;
Roney, Kyle;
Zhu, Weimin;
Brooks, Alan;
Wilsker, Deborah;
Parchment, Ralph E.;
McShane, Lisa M.;
Doroshow, James H.

Publication type:

Article