Works matching AU Papatheodorou, Panagiotis

Results: 25

The antimicrobial peptide Angie 5 inhibits TcdA and TcdB from Clostridioides difficile.

Published in:

Cellular & Molecular Life Sciences, 2025, v. 82, n. 1, p. 1, doi. 10.1007/s00018-025-05799-2

By:

Lietz, Stefanie;
Sokolowski, Lena-Marie;
Lindner, Katrin;
Rodríguez, Armando A.;
Ständker, Ludger;
Vogel, Verena;
Spellerberg, Barbara;
Stenger, Steffen;
Alpízar-Pedraza, Daniel;
Ernst, Katharina;
Papatheodorou, Panagiotis;
Barth, Holger

Publication type:

Article

The Antibiotic Bacitracin Protects Human Intestinal Epithelial Cells and Stem Cell-Derived Intestinal Organoids from Clostridium difficile Toxin TcdB.

Published in:

Stem Cells International, 2019, p. 1, doi. 10.1155/2019/4149762

By:

Zhu, Ziyu;
Schnell, Leonie;
Müller, Bastian;
Müller, Martin;
Papatheodorou, Panagiotis;
Barth, Holger

Publication type:

Article

The enzyme subunit SubA of Shiga toxin-producing E. coli strains demonstrates comparable intracellular transport and cytotoxic activity as the holotoxin SubAB in HeLa and HCT116 cells in vitro.

Published in:

Archives of Toxicology, 2021, v. 95, n. 3, p. 975, doi. 10.1007/s00204-020-02965-2

By:

Sessler, Katharina;
Papatheodorou, Panagiotis;
Wondany, Fanny;
Krause, Maike;
Noettger, Sabrina;
Bernhard, Denise;
Michaelis, Jens;
Schmidt, Herbert;
Barth, Holger

Publication type:

Article

The Compound U18666A Inhibits the Intoxication of Cells by Clostridioides difficile Toxins TcdA and TcdB.

Published in:

Frontiers in Microbiology, 2021, v. 12, p. 1, doi. 10.3389/fmicb.2021.784856

By:

Papatheodorou, Panagiotis;
Kindig, Selina;
Badilla-Lobo, Adriana;
Fischer, Stephan;
Durgun, Ebru;
Thuraisingam, Tharani;
Witte, Alexander;
Song, Shuo;
Aktories, Klaus;
Chaves-Olarte, Esteban;
Rodríguez, César;
Barth, Holger

Publication type:

Article

Human α-Defensin-5 Efficiently Neutralizes Clostridioides difficile Toxins TcdA, TcdB, and CDT.

Published in:

Frontiers in Pharmacology, 2020, v. 11, p. N.PAG, doi. 10.3389/fphar.2020.01204

By:

Korbmacher, Michael;
Fischer, Stephan;
Landenberger, Marc;
Papatheodorou, Panagiotis;
Aktories, Klaus;
Barth, Holger

Publication type:

Article

Exploring the inhibitory potential of the antiarrhythmic drug amiodarone against Clostridioides difficile toxins TcdA and TcdB.

Published in:

Gut Microbes, 2023, v. 15, n. 2, p. 1, doi. 10.1080/19490976.2023.2256695

By:

Schumacher, Judith;
Nienhaus, Astrid;
Heber, Sebastian;
Matylitsky, Jauheni;
Chaves-Olarte, Esteban;
Rodríguez, César;
Barth, Holger;
Papatheodorou, Panagiotis

Publication type:

Article

Inhibition of Clostridioides difficile Toxins TcdA and TcdB by Ambroxol.

Published in:

Frontiers in Pharmacology, 2022, v. 12, p. 1, doi. 10.3389/fphar.2021.809595

By:

Heber, Sebastian;
Barthold, Lara;
Baier, Jan;
Papatheodorou, Panagiotis;
Fois, Giorgio;
Frick, Manfred;
Barth, Holger;
Fischer, Stephan

Publication type:

Article

The enteropathogenic Escherichia coli (EPEC) Map effector is imported into the mitochondrial matrix by the TOM/Hsp70 system and alters organelle morphology.

Published in:

Cellular Microbiology, 2006, v. 8, n. 4, p. 677, doi. 10.1111/j.1462-5822.2005.00660.x

By:

Papatheodorou, Panagiotis;
Domańska, Grażyna;
Öxle, Marius;
Mathieu, Johannes;
Selchow, Olaf;
Kenny, Brendan;
Rassow, Joachim

Publication type:

Article

Lu/BCAM Adhesion Glycoprotein Is a Receptor for Escherichia coli Cytotoxic Necrotizing Factor 1 (CNF1).

Published in:

PLoS Pathogens, 2014, v. 10, n. 1, p. 1, doi. 10.1371/journal.ppat.1003884

By:

Piteau, Marianne;
Papatheodorou, Panagiotis;
Schwan, Carsten;
Schlosser, Andreas;
Aktories, Klaus;
Schmidt, Gudula

Publication type:

Article

Pasteurella Multocida Toxin Prevents Osteoblast Differentiation by Transactivation of the MAP-Kinase Cascade via the Gαq/11 - p63RhoGEF - RhoA Axis

Published in:

PLoS Pathogens, 2013, v. 9, n. 5, p. 1, doi. 10.1371/journal.ppat.1003385

By:

Siegert, Peter;
Schmidt, Gudula;
Papatheodorou, Panagiotis;
Wieland, Thomas;
Aktories, Klaus;
Orth, Joachim H. C.

Publication type:

Article

Helicobacter pylori VacA Toxin/Subunit p34: Targeting of an Anion Channel to the Inner Mitochondrial Membrane.

Published in:

PLoS Pathogens, 2010, v. 6, n. 4, p. 1, doi. 10.1371/journal.ppat.1000878

By:

Domańska, Grazyna;
Motz, Christian;
Meinecke, Michael;
Harsman, Anke;
Papatheodorou, Panagiotis;
Reljic, Boris;
Dian-Lothrop, Elke A.;
Galmiche, Antoine;
Kepp, Oliver;
Becker, Lars;
Günnewig, Kathrin;
Wagner, Richard;
Rassow, Joachim

Publication type:

Article

Inflammation-attenuating effect of carbon dioxide versus room-air environment in a rat laparotomy model: Inflammation-attenuating effect of CO2: P. Ypsilantis et al.

Published in:

Surgical Endoscopy & Other Interventional Techniques, 2025, v. 39, n. 1, p. 376, doi. 10.1007/s00464-024-11388-4

By:

Ypsilantis, Petros;
Stylianaki, Ioanna;
Papachristou, Fotini;
Papatheodorou, Panagiotis;
Svoronos, Christos;
Spyridakis, Konstantinos;
Margaritis, Michael;
Ypsilantou, Ifigenia;
Ypsilantis, Konstantinos;
Papaioannou, Nikolaos;
Karayiannakis, Anastasios;
Pitiakoudis, Michael

Publication type:

Article

Structural determinants for membrane insertion, pore formation and translocation of Clostridium difficile toxin B.

Published in:

Molecular Microbiology, 2012, v. 84, n. 6, p. 1189, doi. 10.1111/j.1365-2958.2012.08078.x

By:

Genisyuerek, Selda;
Papatheodorou, Panagiotis;
Guttenberg, Gregor;
Schubert, Rolf;
Benz, Roland;
Aktories, Klaus

Publication type:

Article

Structural determinants for membrane insertion, pore formation and translocation of Clostridium difficile toxin B.

Published in:

Molecular Microbiology, 2011, v. 79, n. 6, p. 1643, doi. 10.1111/j.1365-2958.2011.07549.x

By:

Genisyuerek, Selda;
Papatheodorou, Panagiotis;
Guttenberg, Gregor;
Schubert, Rolf;
Benz, Roland;
Aktories, Klaus

Publication type:

Article

The Clostridium botulinum C2 Toxin Subunit C2IIa Delivers Enzymes with Positively Charged N-Termini into the Cytosol of Target Cells.

Published in:

Toxins, 2023, v. 15, n. 6, p. 390, doi. 10.3390/toxins15060390

By:

Heber, Sebastian;
Borho, Joscha;
Stadler, Nicole;
Wondany, Fanny;
König, Irina;
Michaelis, Jens;
Papatheodorou, Panagiotis;
Barth, Holger;
Fellermann, Maximilian

Publication type:

Article

Domperidone Protects Cells from Intoxication with Clostridioides difficile Toxins by Inhibiting Hsp70-Assisted Membrane Translocation.

Published in:

Toxins, 2023, v. 15, n. 6, p. 384, doi. 10.3390/toxins15060384

By:

Braune-Yan, Maria;
Jia, Jinfang;
Wahba, Mary;
Schmid, Johannes;
Papatheodorou, Panagiotis;
Barth, Holger;
Ernst, Katharina

Publication type:

Article

The chaperone Hsp90 and PPIases of the cyclophilin and FKBP families facilitate membrane translocation of P hotorhabdus luminescens ADP-ribosyltransferases.

Published in:

Cellular Microbiology, 2014, v. 16, n. 4, p. 490, doi. 10.1111/cmi.12228

By:

Lang, Alexander E.;
Ernst, Katharina;
Lee, Haram;
Papatheodorou, Panagiotis;
Schwan, Carsten;
Barth, Holger;
Aktories, Klaus

Publication type:

Article

Human Serum Albumin Is an Essential Component of the Host Defense Mechanism Against Clostridium difficile Intoxication.

Published in:

2018

By:

Masi, Alessandra di;
Leboffe, Loris;
Polticelli, Fabio;
Tonon, Federica;
Zennaro, Cristina;
Caterino, Marianna;
Stano, Pasquale;
Fischer, Stephan;
Hägele, Marlen;
Müller, Martin;
di Masi, Alessandra;
Kleger, Alexander;
Papatheodorou, Panagiotis;
Nocca, Giuseppina;
Arcovito, Alessandro;
Gori, Andrea;
Ruoppolo, Margherita;
Barth, Holger;
Petrosillo, Nicola;
Ascenzi, Paolo

Publication type:

journal article

Human peptide α‐defensin‐1 interferes with Clostridioides difficile toxins TcdA, TcdB, and CDT.

Published in:

FASEB Journal, 2020, v. 34, n. 5, p. 6244, doi. 10.1096/fj.201902816R

By:

Fischer, Stephan;
Ückert, Anna‐Katharina;
Landenberger, Marc;
Papatheodorou, Panagiotis;
Hoffmann‐Richter, Carola;
Mittler, Ann‐Katrin;
Ziener, Ulrich;
Hägele, Marlen;
Schwan, Carsten;
Müller, Martin;
Kleger, Alexander;
Benz, Roland;
Popoff, Michel R.;
Aktories, Klaus;
Barth, Holger

Publication type:

Article

Revisiting an old antibiotic: bacitracin neutralizes binary bacterial toxins and protects cells from intoxication.

Published in:

FASEB Journal, 2019, v. 33, n. 4, p. 5755, doi. 10.1096/fj.201802453R

By:

Schnell, Leonie;
Felix, Ina;
Müller, Bastian;
Sadi, Mirko;
von Bank, Franziska;
Papatheodorou, Panagiotis;
Popoff, Michel R.;
Aktories, Klaus;
Waltenberger, Eva;
Benz, Roland;
Weichbrodt, Conrad;
Fauler, Michael;
Frick, Manfred;
Barth, Holger

Publication type:

Article

Cytotoxicity of Clostridium difficile toxins A and B requires an active and functional SREBP-2 pathway.

Published in:

FASEB Journal, 2019, v. 33, n. 4, p. 4883, doi. 10.1096/fj.201801440R

By:

Papatheodorou, Panagiotis;
Shuo Song;
López-Ureña, Diana;
Witte, Alexander;
Marques, Felícia;
Ost, Gerhard Stefan;
Schorch, Björn;
Chaves-Olarte, Esteban;
Aktories, Klaus

Publication type:

Article

Inhibition of Clostridioides difficile toxins TcdA and TcdB by the amiodarone derivative dronedarone.

Published in:

Naunyn-Schmiedeberg's Archives of Pharmacology, 2024, v. 397, n. 12, p. 9877, doi. 10.1007/s00210-024-03248-8

By:

Matylitsky, Jauheni;
Krieg, Anica;
Schumacher, Judith;
Borho, Joscha;
Barth, Holger;
Papatheodorou, Panagiotis

Publication type:

Article

Trauma-toxicology: concepts, causes, complications.

Published in:

Naunyn-Schmiedeberg's Archives of Pharmacology, 2024, v. 397, n. 5, p. 2935, doi. 10.1007/s00210-023-02845-3

By:

Barth, Holger;
Worek, Franz;
Steinritz, Dirk;
Papatheodorou, Panagiotis;
Huber-Lang, Markus

Publication type:

Article

Toxin B Variants from Clostridium difficile Strains VPI 10463 and NAP1/027 Share Similar Substrate Profile and Cellular Intoxication Kinetics but Use Different Host Cell Entry Factors.

Published in:

Toxins, 2019, v. 11, n. 6, p. 348, doi. 10.3390/toxins11060348

By:

López-Ureña, Diana;
Orozco-Aguilar, Josué;
Chaves-Madrigal, Yendry;
Ramírez-Mata, Andrea;
Villalobos-Jimenez, Amanda;
Ost, Stefan;
Quesada-Gómez, Carlos;
Rodríguez, César;
Papatheodorou, Panagiotis;
Chaves-Olarte, Esteban

Publication type:

Article

Clostridial Glucosylating Toxins Enter Cells via Clathrin-Mediated Endocytosis.

Published in:

PLoS ONE, 2010, v. 5, n. 5, p. 1, doi. 10.1371/journal.pone.0010673

By:

Papatheodorou, Panagiotis;
Zamboglou, Constantinos;
Genisyuerek, Selda;
Guttenberg, Gregor;
Aktories, Klaus

Publication type:

Article

Works matching AU Papatheodorou, Panagiotis

The antimicrobial peptide Angie 5 inhibits TcdA and TcdB from Clostridioides difficile.

The Antibiotic Bacitracin Protects Human Intestinal Epithelial Cells and Stem Cell-Derived Intestinal Organoids from Clostridium difficile Toxin TcdB.

The enzyme subunit SubA of Shiga toxin-producing E. coli strains demonstrates comparable intracellular transport and cytotoxic activity as the holotoxin SubAB in HeLa and HCT116 cells in vitro.

The Compound U18666A Inhibits the Intoxication of Cells by Clostridioides difficile Toxins TcdA and TcdB.

Human α-Defensin-5 Efficiently Neutralizes Clostridioides difficile Toxins TcdA, TcdB, and CDT.

Exploring the inhibitory potential of the antiarrhythmic drug amiodarone against Clostridioides difficile toxins TcdA and TcdB.

Inhibition of Clostridioides difficile Toxins TcdA and TcdB by Ambroxol.

The enteropathogenic Escherichia coli (EPEC) Map effector is imported into the mitochondrial matrix by the TOM/Hsp70 system and alters organelle morphology.

Lu/BCAM Adhesion Glycoprotein Is a Receptor for <i>Escherichia coli</i> Cytotoxic Necrotizing Factor 1 (CNF1).

<i>Pasteurella Multocida</i> Toxin Prevents Osteoblast Differentiation by Transactivation of the MAP-Kinase Cascade via the Gα<sub>q/11</sub> - p63RhoGEF - RhoA Axis

Helicobacter pylori VacA Toxin/Subunit p34: Targeting of an Anion Channel to the Inner Mitochondrial Membrane.

Inflammation-attenuating effect of carbon dioxide versus room-air environment in a rat laparotomy model: Inflammation-attenuating effect of CO2: P. Ypsilantis et al.

Structural determinants for membrane insertion, pore formation and translocation of Clostridium difficile toxin B.

Structural determinants for membrane insertion, pore formation and translocation of Clostridium difficile toxin B.

The Clostridium botulinum C2 Toxin Subunit C2IIa Delivers Enzymes with Positively Charged N-Termini into the Cytosol of Target Cells.

Domperidone Protects Cells from Intoxication with Clostridioides difficile Toxins by Inhibiting Hsp70-Assisted Membrane Translocation.

The chaperone Hsp90 and PPIases of the cyclophilin and FKBP families facilitate membrane translocation of P hotorhabdus luminescens ADP-ribosyltransferases.

Human Serum Albumin Is an Essential Component of the Host Defense Mechanism Against Clostridium difficile Intoxication.

Human peptide α‐defensin‐1 interferes with Clostridioides difficile toxins TcdA, TcdB, and CDT.

Revisiting an old antibiotic: bacitracin neutralizes binary bacterial toxins and protects cells from intoxication.

Cytotoxicity of Clostridium difficile toxins A and B requires an active and functional SREBP-2 pathway.

Inhibition of Clostridioides difficile toxins TcdA and TcdB by the amiodarone derivative dronedarone.

Trauma-toxicology: concepts, causes, complications.

Toxin B Variants from Clostridium difficile Strains VPI 10463 and NAP1/027 Share Similar Substrate Profile and Cellular Intoxication Kinetics but Use Different Host Cell Entry Factors.

Clostridial Glucosylating Toxins Enter Cells via Clathrin-Mediated Endocytosis.