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DDX3 DEAD-box RNA helicase plays a central role in mitochondrial protein quality control in Leishmania.
- Published in:
- Cell Death & Disease, 2016, v. 7, n. 10, p. e2406, doi. 10.1038/cddis.2016.315
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- Publication type:
- Article
Drug resistance and treatment failure in leishmaniasis: A 21st century challenge.
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- PLoS Neglected Tropical Diseases, 2017, v. 11, n. 12, p. 1, doi. 10.1371/journal.pntd.0006052
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- Publication type:
- Article
Promastigote to amastigote differentiation of Leishmania is markedly delayed in the absence of PERK eIF2alpha kinase-dependent eIF2alpha phosphorylation.
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- Cellular Microbiology, 2011, v. 13, n. 7, p. 1059, doi. 10.1111/j.1462-5822.2011.01602.x
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- Publication type:
- Article
Increased transport of pteridines compensates for mutations in the high affinity folate transporter and contributes to methotrexate resistance in the protozoan parasite Leishmania tarentolae.
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- EMBO Journal, 1999, v. 18, n. 9, p. 2342, doi. 10.1093/emboj/18.9.2342
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- Publication type:
- Article
Disruption of the trypanothione reductase gene of Leishmania decreases its ability to survive oxidative stress in macrophages.
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- EMBO Journal, 1997, v. 16, n. 10, p. 2590, doi. 10.1093/emboj/16.10.2590
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- Publication type:
- Article
Organization and evolution of two SIDER retroposon subfamilies and their impact on the Leishmania genome.
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- BMC Genomics, 2009, v. 10, p. 1, doi. 10.1186/1471-2164-10-240
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- Publication type:
- Article
Genome-wide gene expression profiling analysis of Leishmania major and Leishmania infantum developmental stages reveals substantial differences between the two species.
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- BMC Genomics, 2008, v. 9, p. 1, doi. 10.1186/1471-2164-9-255
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- Publication type:
- Article
Altered expression of an RBP-associated arginine methyltransferase 7 in L eishmania major affects parasite infection.
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- Molecular Microbiology, 2014, v. 94, n. 5, p. 1085, doi. 10.1111/mmi.12819
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- Publication type:
- Article
An Alba-domain protein contributes to the stage-regulated stability of amastin transcripts in Leishmania.
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- Molecular Microbiology, 2014, v. 91, n. 3, p. 548, doi. 10.1111/mmi.12478
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- Publication type:
- Article
Selective inactivation of SIDER2 retroposon-mediated mRNA decay contributes to stage- and species-specific gene expression in Leishmania.
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- Molecular Microbiology, 2010, v. 77, n. 2, p. 471, doi. 10.1111/j.1365-2958.2010.07226.x
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- Publication type:
- Article
Parameters controlling the rate of gene targeting frequency in the protozoan parasite Leishmania.
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- Nucleic Acids Research, 1997, v. 25, n. Supplement, p. 4278, doi. 10.1093/nar/25.21.4278
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- Publication type:
- Article
Species-Specific Antimonial Sensitivity in Leishmania Is Driven by Post-Transcriptional Regulation of AQP1.
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- PLoS Neglected Tropical Diseases, 2015, v. 9, n. 2, p. 1, doi. 10.1371/journal.pntd.0003500
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- Publication type:
- Article
Species-Specific Antimonial Sensitivity in Leishmania Is Driven by Post-Transcriptional Regulation of AQP1.
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- PLoS Neglected Tropical Diseases, 2015, v. 9, n. 2, p. 1, doi. 10.1371/journal.pntd.0003500
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- Publication type:
- Article
Enhanced Protective Efficacy of Nonpathogenic Recombinant Leishmania tarentolae Expressing Cysteine Proteinases Combined with a Sand Fly Salivary Antigen.
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- PLoS Neglected Tropical Diseases, 2014, v. 8, n. 3, p. 1, doi. 10.1371/journal.pntd.0002751
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- Publication type:
- Article
Enhanced Protective Efficacy of Nonpathogenic Recombinant <i>Leishmania tarentolae</i> Expressing Cysteine Proteinases Combined with a Sand Fly Salivary Antigen.
- Published in:
- PLoS Neglected Tropical Diseases, 2014, v. 8, n. 3, p. 1, doi. 10.1371/journal.pntd.0002751
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- Publication type:
- Article
Development of Novel Prime-Boost Strategies Based on a Tri-Gene Fusion Recombinant L. tarentolae Vaccine against Experimental Murine Visceral Leishmaniasis.
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- PLoS Neglected Tropical Diseases, 2013, v. 7, n. 4, p. 1, doi. 10.1371/journal.pntd.0002174
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- Publication type:
- Article
Development of Novel Prime-Boost Strategies Based on a Tri-Gene Fusion Recombinant L. tarentolae Vaccine against Experimental Murine Visceral Leishmaniasis.
- Published in:
- PLoS Neglected Tropical Diseases, 2013, v. 7, n. 4, p. 1, doi. 10.1371/journal.pntd.0002174
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- Publication type:
- Article
Improving the prediction of mRNA extremities in the parasitic protozoan Leishmania.
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- BMC Bioinformatics, 2008, v. 9, p. 1, doi. 10.1186/1471-2105-9-158
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- Publication type:
- Article
The AAA + ATPase valosin-containing protein (VCP)/p97/Cdc48 interaction network in Leishmania.
- Published in:
- Scientific Reports, 2020, v. 10, n. 1, p. N.PAG, doi. 10.1038/s41598-020-70010-4
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- Publication type:
- Article
Novel Features of a PIWI-Like Protein Homolog in the Parasitic Protozoan Leishmania.
- Published in:
- PLoS ONE, 2012, v. 7, n. 12, p. 1, doi. 10.1371/journal.pone.0052612
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- Publication type:
- Article
Translational Control through eIF2alpha Phosphorylation during the Leishmania Differentiation Process.
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- PLoS ONE, 2012, v. 7, n. 5, p. 1, doi. 10.1371/journal.pone.0035085
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- Publication type:
- Article
Protection against Leishmania major challenge infection in mice vaccinated with live recombinant parasites expressing a cytotoxic gene.
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- 1998
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- Publication type:
- journal article
A combined proteomic and transcriptomic approach to the study of stage differentiation in Leishmania infantum.
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- Proteomics, 2006, v. 6, n. 12, p. 3567, doi. 10.1002/pmic.200500853
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- Publication type:
- Article
A proteomic approach to identify developmentally regulated proteins in Leishmania infantum.
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- Proteomics, 2002, v. 2, n. 8, p. 1007, doi. 10.1002/1615-9861(200208)2:8<1007::AID-PROT1007>3.0.CO;2-G
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- Publication type:
- Article
Valosin‐containing protein VCP/p97 is essential for the intracellular development of Leishmania and its survival under heat stress.
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- Cellular Microbiology, 2018, v. 20, n. 10, p. 1, doi. 10.1111/cmi.12867
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- Publication type:
- Article
Genetic depletion of the RNA helicase DDX3 leads to impaired elongation of translating ribosomes triggering co-translational quality control of newly synthesized polypeptides.
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- Nucleic Acids Research, 2021, v. 49, n. 16, p. 9459, doi. 10.1093/nar/gkab667
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- Publication type:
- Article
Genome sequencing of the lizard parasite Leishmania tarentolae reveals loss of genes associated to the intracellular stage of human pathogenic species.
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- Nucleic Acids Research, 2012, v. 40, n. 3, p. 1131, doi. 10.1093/nar/gkr834
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- Publication type:
- Article
Rapid decay of unstable Leishmania mRNAs bearing a conserved retroposon signature 3′-UTR motif is initiated by a site-specific endonucleolytic cleavage without prior deadenylation.
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- Nucleic Acids Research, 2010, v. 38, n. 17, p. 5867, doi. 10.1093/nar/gkq349
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- Publication type:
- Article
Akt Determines Cell Fate Through Inhibition of the PERK-eIF2α Phosphorylation Pathway.
- Published in:
- Science Signaling, 2011, v. 4, n. 192, p. 1, doi. 10.1126/scisignal.2001630
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- Publication type:
- Article
Identification of novel proteins and mRNAs differentially bound to the Leishmania Poly(A) Binding Proteins reveals a direct association between PABP1, the RNA-binding protein RBP23 and mRNAs encoding ribosomal proteins.
- Published in:
- PLoS Neglected Tropical Diseases, 2021, v. 15, n. 10, p. 1, doi. 10.1371/journal.pntd.0009899
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- Publication type:
- Article
RNA secondary structure and nucleotide composition of the conserved hallmark sequence of Leishmania SIDER2 retroposons are essential for endonucleolytic cleavage and mRNA degradation.
- Published in:
- PLoS ONE, 2017, v. 12, n. 7, p. 1, doi. 10.1371/journal.pone.0180678
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- Publication type:
- Article
Deadenylation-independent stage-specific mRNA degradation in Leishmania.
- Published in:
- Nucleic Acids Research, 2008, v. 36, n. 5, p. 1634, doi. 10.1093/nar/gkn019
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- Publication type:
- Article
Formation of linear inverted repeat amplicons following targeting of an essential gene in Leishmania.
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- Nucleic Acids Research, 2005, v. 33, n. 5, p. 1699, doi. 10.1093/nar/gki304
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- Publication type:
- Article
The ribosomal RNA gene promoter and adjacent cis‐acting DNA sequences govern plasmid DNA partitioning and stable inheritance in the parasitic protozoan Leishmania.
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- Nucleic Acids Research, 2004, v. 32, n. 9, p. 2925, doi. 10.1093/nar/gkh617
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- Publication type:
- Article
Modulation of gene expression in Leishmania drug resistant mutants as determined by targeted DNA microarrays.
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- Nucleic Acids Research, 2003, v. 31, n. 20, p. 5886, doi. 10.1093/nar/gkg806
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- Publication type:
- Article
Role of the locus and of the resistance gene on gene amplification frequency in methotrexate resistant Leishmania tarentolae.
- Published in:
- Nucleic Acids Research, 1999, v. 27, n. 18, p. 3653, doi. 10.1093/nar/27.18.3653
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- Publication type:
- Article
Characterization of a Leishmania donovani gene encoding a protein that closely resembles a type IB topoisomerase.
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- Nucleic Acids Research, 1999, v. 27, n. 13, p. 2745, doi. 10.1093/nar/27.13.2745
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- Publication type:
- Article
Coupling chemical mutagenesis to next generation sequencing for the identification of drug resistance mutations in Leishmania.
- Published in:
- Nature Communications, 2019, v. 10, n. 1, p. N.PAG, doi. 10.1038/s41467-019-13344-6
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- Publication type:
- Article
Novel strategy using live non-pathogenic Leishmania expressing selected parasite antigens as a candidate vaccine for leishmaniasis.
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- 2011
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- Publication type:
- Abstract
DC-SIGN-Mediated Transfer of HIV-1 Is Compromised by the Ability of Leishmania infantum to Exploit DC-SIGN as a Ligand.
- Published in:
- Journal of Infectious Diseases, 2005, v. 191, n. 10, p. 1665, doi. 10.1086/429673
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- Publication type:
- Article
Genome-Wide Stochastic Adaptive DNA Amplification at Direct and Inverted DNA Repeats in the Parasite <i>Leishmania</i>.
- Published in:
- PLoS Biology, 2014, v. 12, n. 5, p. 1, doi. 10.1371/journal.pbio.1001868
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- Publication type:
- Article
Distinctive features of the oropharyngeal microbiome in Inuit of Nunavik and correlations of mild to moderate bronchial obstruction with dysbiosis.
- Published in:
- Scientific Reports, 2023, v. 13, n. 1, p. 1, doi. 10.1038/s41598-023-43821-4
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- Publication type:
- Article
Distinctive features of the oropharyngeal microbiome in Inuit of Nunavik and correlations of mild to moderate bronchial obstruction with dysbiosis.
- Published in:
- Scientific Reports, 2023, v. 13, n. 1, p. 1, doi. 10.1038/s41598-023-43821-4
- By:
- Publication type:
- Article
A proteomic analysis of penicillin resistance in Streptococcus pneumoniae reveals a novel role for PstS, a subunit of the phosphate ABC transporter.
- Published in:
- Molecular Microbiology, 2005, v. 58, n. 5, p. 1430, doi. 10.1111/j.1365-2958.2005.04914.x
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- Publication type:
- Article
Differential Subcellular Localization of Leishmania Alba-Domain Proteins throughout the Parasite Development.
- Published in:
- PLoS ONE, 2015, v. 10, n. 9, p. 1, doi. 10.1371/journal.pone.0137243
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- Publication type:
- Article
Evaluation of Live Recombinant Nonpathogenic Leishmania tarentolae Expressing Cysteine Proteinase and A2 Genes as a Candidate Vaccine against Experimental Canine Visceral Leishmaniasis.
- Published in:
- PLoS ONE, 2015, v. 10, n. 7, p. 1, doi. 10.1371/journal.pone.0132794
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- Publication type:
- Article
Members of a Large Retroposon Family Are Determinants of Post-Transcriptional Gene Expression in Leishmania.
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- PLoS Pathogens, 2007, v. 3, n. 9, p. 1291, doi. 10.1371/journal.ppat.0030136
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- Publication type:
- Article