Found: 4

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  • Mitochondrial complex IV defects induce metabolic and signaling perturbations that expose potential vulnerabilities in HCT116 cells .

    Published in:
    FEBS Open Bio, 2022, v. 12, n. 5, p. 959, doi. 10.1002/2211-5463.13398
    By:
    • Uchenunu, Oro;
    • Zhdanov, Alexander V.;
    • Hutton, Phillipe;
    • Jovanovic, Predrag;
    • Ye Wang;
    • Andreev, Dmitry E.;
    • Hulea, Laura;
    • Papadopoli, David J.;
    • Avizonis, Daina;
    • Baranov, Pavel V.;
    • Pollak, Michael N.;
    • Papkovsky, Dmitri B.;
    • Topisirovic, Ivan
    Publication type:
    Article

  • Adaptive translational reprogramming of metabolism limits the response to targeted therapy in BRAF<sup>V600</sup> melanoma.

    Published in:
    Nature Communications, 2022, v. 13, n. 1, p. 1, doi. 10.1038/s41467-022-28705-x
    By:
    • Smith, Lorey K.;
    • Parmenter, Tiffany;
    • Kleinschmidt, Margarete;
    • Kusnadi, Eric P.;
    • Kang, Jian;
    • Martin, Claire A.;
    • Lau, Peter;
    • Patel, Riyaben;
    • Lorent, Julie;
    • Papadopoli, David;
    • Trigos, Anna;
    • Ward, Teresa;
    • Rao, Aparna D.;
    • Lelliott, Emily J.;
    • Sheppard, Karen E.;
    • Goode, David;
    • Hicks, Rodney J.;
    • Tiganis, Tony;
    • Simpson, Kaylene J.;
    • Larsson, Ola
    Publication type:
    Article

  • Copper bioavailability is a KRAS-specific vulnerability in colorectal cancer.

    Published in:
    Nature Communications, 2020, v. 11, n. 1, p. 1, doi. 10.1038/s41467-020-17549-y
    By:
    • Aubert, Léo;
    • Nandagopal, Neethi;
    • Steinhart, Zachary;
    • Lavoie, Geneviève;
    • Nourreddine, Sami;
    • Berman, Jacob;
    • Saba-El-Leil, Marc K.;
    • Papadopoli, David;
    • Lin, Sichun;
    • Hart, Traver;
    • Macleod, Graham;
    • Topisirovic, Ivan;
    • Gaboury, Louis;
    • Fahrni, Christoph J.;
    • Schramek, Daniel;
    • Meloche, Sylvain;
    • Angers, Stephane;
    • Roux, Philippe P.
    Publication type:
    Article

  • PRDM15 is a key regulator of metabolism critical to sustain B-cell lymphomagenesis.

    Published in:
    Nature Communications, 2020, v. 11, n. 1, p. 1, doi. 10.1038/s41467-020-17064-0
    By:
    • Mzoughi, Slim;
    • Fong, Jia Yi;
    • Papadopoli, David;
    • Koh, Cheryl M.;
    • Hulea, Laura;
    • Pigini, Paolo;
    • Di Tullio, Federico;
    • Andreacchio, Giuseppe;
    • Hoppe, Michal Marek;
    • Wollmann, Heike;
    • Low, Diana;
    • Caldez, Matias J.;
    • Peng, Yanfen;
    • Torre, Denis;
    • Zhao, Julia N.;
    • Uchenunu, Oro;
    • Varano, Gabriele;
    • Motofeanu, Corina-Mihaela;
    • Lakshmanan, Manikandan;
    • Teo, Shun Xie
    Publication type:
    Article