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Absence of Apolipoprotein E is associated with exacerbation of prion pathology and promotes microglial neurodegenerative phenotype.
- Published in:
- Acta Neuropathologica Communications, 2021, v. 9, n. 1, p. 1, doi. 10.1186/s40478-021-01261-z
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- Publication type:
- Article
Apolipoprotein E4 Effects a Distinct Transcriptomic Profile and Dendritic Arbor Characteristics in Hippocampal Neurons Cultured in vitro.
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- Frontiers in Aging Neuroscience, 2022, v. 14, p. 1, doi. 10.3389/fnagi.2022.845291
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- Publication type:
- Article
The APOE4 Allele Exacerbates Pathology in a Mouse Model of Prion Disease.
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- Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2023, v. 19, p. 1, doi. 10.1002/alz.072559
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- Publication type:
- Article
Role of Peroxiredoxin 6 in the Development of Tau Pathology.
- Published in:
- Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2023, v. 19, p. 1, doi. 10.1002/alz.072575
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- Publication type:
- Article
Absence of Apolipoprotein E Exacerbates Prion Pathology and Promote Microglial Mediated Neurodegeneration.
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- Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2022, v. 18, n. 3, p. 1, doi. 10.1002/alz.060686
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- Publication type:
- Article
Peroxiredoxin 6 Regulates Glia Toxicity in Tau Mediated Neurodegeneration.
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- Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2022, v. 18, n. 3, p. 1, doi. 10.1002/alz.060472
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- Publication type:
- Article
P3‐187: ANTI‐PRION PROTEIN ANTIBODY 6D11 DISRUPTS RECYCLING PROPAGATION OF THE PRP<sup>SC</sup> CONFORMER AND RESTORES CELLULAR PROTEOSTASIS OF PRION PROTEIN.
- Published in:
- Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2019, v. 15, p. P1001, doi. 10.1016/j.jalz.2019.06.3216
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- Publication type:
- Article
P2‐056: TARGETING APP TRANSLATION FOR ALZHEIMER'S DISEASE THERAPY.
- Published in:
- Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2019, v. 15, p. P592, doi. 10.1016/j.jalz.2019.06.2463
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- Publication type:
- Article
P1‐173: PEROXIREDOXIN 6 GENE DOSAGE AFFECTS ASTROCYTIC AND MICROGLIA REACTIVITY AND MODULATES PATHOLOGICAL PHENOTYPE IN ALZHEIMER MODEL MICE.
- Published in:
- Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2019, v. 15, p. P303, doi. 10.1016/j.jalz.2019.06.728
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- Publication type:
- Article
CHARACTERIZATION OF A SMALL-MOLECULE APP TRANSLATION INHIBITOR FOR ALZHEIMER’S DISEASE PREVENTION AND THERAPY.
- Published in:
- Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2017, v. 13, p. P627, doi. 10.1016/j.jalz.2017.06.709
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- Publication type:
- Article
ANTI-PRP MAB 6D11 DISRUPTS CELLULAR TRAFFICKING OF PRPC AND PRPSC AND TARGETS PRPSC FOR LYSOSOMAL DEGRADATION.
- Published in:
- Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2017, v. 13, p. P333, doi. 10.1016/j.jalz.2017.06.054
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- Publication type:
- Article
APOLIPOPROTEIN E GENOTYPE DIFFERENTIALLY MODULATES EFFECTS OF ANTI-AB IMMUNOTHERAPY.
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- Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2016, v. 12, p. P381, doi. 10.1016/j.jalz.2016.06.716
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- Publication type:
- Article
Pyridin-2-ylmethylamine derivatives as novel inhibitors of aβ aggregation and toxicity
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- 2011
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- Publication type:
- Abstract
Therapeutic anti-Prion Monoclonal Antibody 6D11 Facilitates PrPsc Degradation in Prion Cell culture model
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- 2011
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- Publication type:
- Abstract
Therapeutic mechanisms of anti-prion monoclonal antibodies
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- 2010
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- Publication type:
- Abstract
Anti-aggregation peptide/peptoid chimeric oligomers exhibiting neuroprotective effects
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- 2010
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- Publication type:
- Abstract
Distinct expression pattern of molecular chaperones associated with accumulation of PrPSc in different mouse adapted scrapie strains
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- 2010
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- Publication type:
- Abstract
P2-212: Suppression of PrP<sup>Sc</sup> replication in follicular dendritic cells in vitro and in vivo by therapeutic 6D11 monoclonal antibody
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- 2008
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- Publication type:
- Abstract
P1-441: Increased parenchymal and vascular Aβ deposition in Alzheimer's disease transgenic mice with chronic hyperglycemia
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- 2008
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- Publication type:
- Abstract
P4-433: Therapeutically effective anti-prion protein monoclonal antibodies
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- 2006
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- Publication type:
- Abstract
P4-254: The apolipoprotein E/Aβ interaction as a novel therapeutic target for Alzheimer’s disease
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- 2006
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- Publication type:
- Abstract
P4-123: PrP<sup>Sc</sup> Aggregates in the ocular lens of symptomatic and pre-symptomatic prion infected mice
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- 2006
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- Publication type:
- Abstract
P4-433: Therapeutically effective anti-prion protein monoclonal antibodies
- Published in:
- 2006
- By:
- Publication type:
- Abstract
P4-254: The apolipoprotein E/Aβ interaction as a novel therapeutic target for Alzheimer’s disease
- Published in:
- 2006
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- Publication type:
- Abstract
P4-123: PrP<sup>Sc</sup> Aggregates in the ocular lens of symptomatic and pre-symptomatic prion infected mice
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- 2006
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- Publication type:
- Abstract
Blocking the apolipoprotein E/amyloid-B interaction reduces amyloid-B load in AD transgenic mice
- Published in:
- 2005
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- Publication type:
- Abstract
Reply: To PMID 24687915.
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- 2014
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- Publication type:
- Letter
Reply.
- Published in:
- Annals of Neurology, 2014, v. 76, n. 4, p. 630, doi. 10.1002/ana.24253
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- Publication type:
- Article
Modulation of amyloid precursor protein expression reduces β-amyloid deposition in a mouse model.
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- 2014
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- Publication type:
- journal article
Modulation of amyloid precursor protein expression reduces β-amyloid deposition in a mouse model.
- Published in:
- Annals of Neurology, 2014, v. 75, n. 5, p. 684, doi. 10.1002/ana.24149
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- Publication type:
- Article
Clearance and prevention of prion infection in cell culture by anti-PrP antibodies.
- Published in:
- European Journal of Neuroscience, 2006, v. 23, n. 10, p. 2635, doi. 10.1111/j.1460-9568.2006.04805.x
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- Publication type:
- Article
APOE Genotype Differentially Modulates Effects of Anti-Aβ, Passive Immunization in APP Transgenic Mice.
- Published in:
- Molecular Neurodegeneration, 2017, v. 12, p. 1, doi. 10.1186/s13024-017-0156-1
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- Publication type:
- Article
Anti-prion Protein Antibody 6D11 Restores Cellular Proteostasis of Prion Protein Through Disrupting Recycling Propagation of PrP<sup>Sc</sup> and Targeting PrP<sup>Sc</sup> for Lysosomal Degradation.
- Published in:
- Molecular Neurobiology, 2019, v. 56, n. 3, p. 2073, doi. 10.1007/s12035-018-1208-4
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- Publication type:
- Article
Peroxiredoxin 6 mediates protective function of astrocytes in Aβ proteostasis.
- Published in:
- Molecular Neurodegeneration, 2020, v. 15, n. 1, p. 1, doi. 10.1186/s13024-020-00401-8
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- Publication type:
- Article