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Preclinical evaluation of proteolytic targeting of LCK as a therapeutic approach in T cell acute lymphoblastic leukemia.
- Published in:
- Science Translational Medicine, 2022, v. 14, n. 659, p. 1, doi. 10.1126/scitranslmed.abo5228
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- Publication type:
- Article
Using plasma topotecan pharmacokinetics to estimate topotecan exposure in cerebrospinal fluid of children with medulloblastoma.
- Published in:
- Neuro-Oncology, 2006, v. 8, n. 2, p. 89, doi. 10.1215/15228517-2005-004
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- Publication type:
- Article
Pharmacokinetically guided dosing of oral sorafenib in pediatric hepatocellular carcinoma: A simulation study.
- Published in:
- CTS: Clinical & Translational Science, 2021, v. 14, n. 6, p. 2152, doi. 10.1111/cts.13069
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- Publication type:
- Article
Identification of small molecules that mitigate vincristine‐induced neurotoxicity while sensitizing leukemia cells to vincristine.
- Published in:
- CTS: Clinical & Translational Science, 2021, v. 14, n. 4, p. 1490, doi. 10.1111/cts.13012
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- Publication type:
- Article
Changes in body mass index, height, and weight in children during and after therapy for acute lymphoblastic leukemia.
- Published in:
- 2018
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- Publication type:
- journal article
Bone mineral density in children with acute lymphoblastic leukemia.
- Published in:
- 2018
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- Publication type:
- journal article
Resumption of high-dose methotrexate after acute kidney injury and glucarpidase use in pediatric oncology patients.
- Published in:
- Cancer (0008543X), 2012, v. 118, n. 17, p. 4321, doi. 10.1002/cncr.27378
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- Publication type:
- Article
Modeling Mechanisms of In Vivo Variability in Methotrexate Accumulation and Folate Pathway Inhibition in Acute Lymphoblastic Leukemia Cells.
- Published in:
- PLoS Computational Biology, 2010, v. 6, n. 12, p. 1, doi. 10.1371/journal.pcbi.1001019
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- Publication type:
- Article
Activity of the Multikinase Inhibitor Sorafenib in Combination With Cytarabine in Acute Myeloid Leukemia.
- Published in:
- JNCI: Journal of the National Cancer Institute, 2011, v. 103, n. 11, p. 893, doi. 10.1093/jnci/djr107
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- Publication type:
- Article
The SWI/SNF Chromatin-Remodeling Complex and Glucocorticoid Resistance in Acute Lymphoblastic Leukemia.
- Published in:
- JNCI: Journal of the National Cancer Institute, 2008, v. 100, n. 24, p. 1792, doi. 10.1093/jnci/djn416
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- Publication type:
- Article
Asparaginase combined with discontinuous dexamethasone improves antileukemic efficacy without increasing osteonecrosis in preclinical models.
- Published in:
- PLoS ONE, 2019, v. 14, n. 5, p. 1, doi. 10.1371/journal.pone.0216328
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- Publication type:
- Article
Adalimumab Clearance, Rather Than Trough Level, May Have Greatest Relevance to Crohn's Disease Therapeutic Outcomes Assessed Clinically and Endoscopically.
- Published in:
- Journal of Crohn's & Colitis, 2024, v. 18, n. 2, p. 212, doi. 10.1093/ecco-jcc/jjad140
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- Publication type:
- Article
Association between obesity and neurocognitive function in survivors of childhood acute lymphoblastic leukemia treated only with chemotherapy.
- Published in:
- Cancer (0008543X), 2021, v. 127, n. 17, p. 3202, doi. 10.1002/cncr.33624
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- Publication type:
- Article
Phase 1 study of bendamustine in combination with clofarabine, etoposide, and dexamethasone in pediatric patients with relapsed or refractory hematologic malignancies.
- Published in:
- Cancer (0008543X), 2021, v. 127, n. 12, p. 2074, doi. 10.1002/cncr.33465
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- Publication type:
- Article
Safety, pharmacokinetics, and pharmacodynamics of panobinostat in children, adolescents, and young adults with relapsed acute myeloid leukemia.
- Published in:
- Cancer (0008543X), 2020, v. 126, n. 21, p. 4800, doi. 10.1002/cncr.33156
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- Publication type:
- Article
Incidence of hip and knee osteonecrosis and their associations with bone mineral density in children with acute lymphoblastic leukaemia.
- Published in:
- British Journal of Haematology, 2020, v. 189, n. 4, p. e177, doi. 10.1111/bjh.16589
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- Publication type:
- Article
Treosulfan Exposure Predicts Thalassemia‐Free Survival in Patients with Beta Thalassemia Major Undergoing Allogeneic Hematopoietic Cell Transplantation.
- Published in:
- Clinical Pharmacology & Therapeutics, 2024, v. 115, n. 1, p. 116, doi. 10.1002/cpt.3078
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- Publication type:
- Article
Application of a highly specific and sensitive fluorescent HPLC method for topotecan lactone in whole blood.
- Published in:
- Biomedical Chromatography, 2009, v. 23, n. 7, p. 707, doi. 10.1002/bmc.1173
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- Publication type:
- Article
Ommaya reservoir use in pediatric ALL and NHL: a review at St. Jude Children's Research Hospital.
- Published in:
- Cancer Chemotherapy & Pharmacology, 2024, v. 93, n. 6, p. 617, doi. 10.1007/s00280-024-04653-9
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- Publication type:
- Article
Pharmacokinetics and safety of bendamustine in the BEABOVP regimen for the treatment of pediatric patients with Hodgkin lymphoma.
- Published in:
- Cancer Chemotherapy & Pharmacology, 2023, v. 92, n. 1, p. 1, doi. 10.1007/s00280-023-04540-9
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- Publication type:
- Article
Pharmacodynamics of cerebrospinal fluid asparagine after asparaginase.
- Published in:
- Cancer Chemotherapy & Pharmacology, 2021, v. 88, n. 4, p. 655, doi. 10.1007/s00280-021-04315-0
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- Publication type:
- Article
Pharmacokinetics of alemtuzumab in pediatric patients undergoing ex vivo T-cell-depleted haploidentical hematopoietic cell transplantation.
- Published in:
- Cancer Chemotherapy & Pharmacology, 2020, v. 86, n. 6, p. 711, doi. 10.1007/s00280-020-04160-7
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- Publication type:
- Article
Pharmacokinetics, immunogenicity, and safety of weekly dosing of brentuximab vedotin in pediatric patients with Hodgkin lymphoma.
- Published in:
- 2016
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- Publication type:
- journal article
Population pharmacokinetics of Daunorubicin in adult patients with acute myeloid leukemia.
- Published in:
- 2016
- By:
- Publication type:
- journal article
Sorafenib metabolism, transport, and enterohepatic recycling: physiologically based modeling and simulation in mice.
- Published in:
- 2016
- By:
- Publication type:
- journal article
Model Informed Precision Dosing Tool Forecasts Trough Infliximab and Associates with Disease Status and Tumor Necrosis Factor-Alpha Levels of Inflammatory Bowel Diseases.
- Published in:
- Journal of Clinical Medicine, 2022, v. 11, n. 12, p. 3316, doi. 10.3390/jcm11123316
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- Publication type:
- Article
Limited sampling strategies for accurate determination of extended half‐life factor VIII pharmacokinetics in severe haemophilia A patients.
- Published in:
- Haemophilia, 2021, v. 27, n. 3, p. 408, doi. 10.1111/hae.14288
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- Publication type:
- Article
Pharmacokinetic basis for dosing high‐dose methotrexate in infants and young children with malignant brain tumours.
- Published in:
- British Journal of Clinical Pharmacology, 2020, v. 86, n. 2, p. 362, doi. 10.1111/bcp.14160
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- Publication type:
- Article
Expression of SMARCB1 modulates steroid sensitivity in human lymphoblastoid cells: identification of a promoter snp that alters PARP1 binding and SMARCB1 expression.
- Published in:
- Human Molecular Genetics, 2007, v. 16, n. 19, p. 2261, doi. 10.1093/hmg/ddm178
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- Publication type:
- Article
Population PK/PD Model of Homocysteine Concentrations after High-Dose Methotrexate Treatment in Patients with Acute Lymphoblastic Leukemia.
- Published in:
- PLoS ONE, 2012, v. 7, n. 9, p. 1, doi. 10.1371/journal.pone.0046015
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- Publication type:
- Article
Higher plasma asparaginase activity after intramuscular than intravenous Erwinia asparaginase.
- Published in:
- 2020
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- Publication type:
- journal article
Asparaginase formulation impacts hypertriglyceridemia during therapy for acute lymphoblastic leukemia.
- Published in:
- 2020
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- Publication type:
- journal article
Hypersensitivity reaction to high-dose methotrexate and successful rechallenge in a pediatric patient with osteosarcoma.
- Published in:
- Pediatric Blood & Cancer, 2014, v. 61, n. 2, p. 373, doi. 10.1002/pbc.24741
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- Publication type:
- Article
In Vivo Response to Methotrexate Forecasts Outcome of Acute Lymphoblastic Leukemia and Has a Distinct Gene Expression Profile.
- Published in:
- PLoS Medicine, 2008, v. 5, n. 4, p. e83, doi. 10.1371/journal.pmed.0050083
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- Publication type:
- Article
Pharmacogenomics of intracellular methotrexate polyglutamates in patients' leukemia cells in vivo.
- Published in:
- 2020
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- Publication type:
- journal article
Folate pathway gene expression differs in subtypes of acute lymphoblastic leukemia and influences methotrexate pharmacodynamics.
- Published in:
- 2005
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- Publication type:
- journal article
Erratum to: Between-course targeting of methotrexate exposure using pharmacokinetically guided dosage adjustments.
- Published in:
- 2013
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- Publication type:
- Correction notice
Development and validation of limited sampling models for topotecan lactone pharmacokinetic studies in children.
- Published in:
- Cancer Chemotherapy & Pharmacology, 2006, v. 57, n. 4, p. 475, doi. 10.1007/s00280-005-0062-z
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- Publication type:
- Article
Development of a pharmacokinetic limited sampling model for temozolomide and its active metabolite MTIC.
- Published in:
- 2005
- By:
- Publication type:
- journal article
Interferon-gamma pharmacokinetics and pharmacodynamics in patients with colorectal cancer.
- Published in:
- Cancer Chemotherapy & Pharmacology, 2004, v. 53, n. 3, p. 253
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- Publication type:
- Article
Population pharmacokinetics of temozolomide and metabolites in infants and children with primary central nervous system tumors.
- Published in:
- 2003
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- Publication type:
- journal article
Apoptosome activation, an important molecular instigator in 6-mercaptopurine induced Leydig cell death.
- Published in:
- Scientific Reports, 2015, p. 16488, doi. 10.1038/srep16488
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- Publication type:
- Article
The Combination of Predictive Factors of Pharmacokinetic Origin Associates with Enhanced Disease Control during Treatment of Pediatric Crohn's Disease with Infliximab.
- Published in:
- Pharmaceutics, 2023, v. 15, n. 10, p. 2408, doi. 10.3390/pharmaceutics15102408
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- Publication type:
- Article
Pharmacokinetics and Pharmacodynamics of Treosulfan in Patients With Thalassemia Major Undergoing Allogeneic Hematopoietic Stem Cell Transplantation.
- Published in:
- Clinical Pharmacology & Therapeutics, 2018, v. 104, n. 3, p. 575, doi. 10.1002/cpt.988
- By:
- Publication type:
- Article
MicroRNAs Form Triplexes with Double Stranded DNA at Sequence-Specific Binding Sites; a Eukaryotic Mechanism via which microRNAs Could Directly Alter Gene Expression.
- Published in:
- PLoS Computational Biology, 2016, v. 12, n. 2, p. 1, doi. 10.1371/journal.pcbi.1004744
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- Publication type:
- Article