Works by Panek, Dawid

Results: 9

Multifunctional, Fluorene‐Based Modulator of Cholinergic and GABAergic Neurotransmission as a Novel Drug Candidate for Palliative Treatment of Alzheimer's Disease.

Published in:

Angewandte Chemie International Edition, 2025, v. 64, n. 6, p. 1, doi. 10.1002/anie.202420510

By:

Panek, Dawid;
Pasieka, Anna;
Jończyk, Jakub;
Gawlińska, Milena;
Zaręba, Paula;
Siwek, Agata;
Wolak, Małgorzata;
Mordyl, Barbara;
Głuch‐Lutwin, Monika;
Latacz, Gniewomir;
Brazzolotto, Xavier;
Chantegreil, Fabien;
Nachon, Florian;
Zdarova Karasova, Jana;
Pejchal, Jaroslav;
Mzik, Martin;
Sestak, Vit;
Prchal, Lukas;
Odvarkova, Jitka;
Soukup, Ondrej

Publication type:

Article

Multidirectional in vitro and in cellulo studies as a tool for identification of multi-target-directed ligands aiming at symptoms and causes of Alzheimer's disease.

Published in:

Journal of Enzyme Inhibition & Medicinal Chemistry, 2020, v. 35, n. 1, p. 1944, doi. 10.1080/14756366.2020.1835882

By:

Szałaj, Natalia;
Godyń, Justyna;
Jończyk, Jakub;
Pasieka, Anna;
Panek, Dawid;
Wichur, Tomasz;
Więckowski, Krzysztof;
Zaręba, Paula;
Bajda, Marek;
Pislar, Anja;
Malawska, Barbara;
Sabate, Raimon;
Więckowska, Anna

Publication type:

Article

DESIGN, SYNTHESIS AND BIOLOGICAL EVALUATION OF NOVEL BENZYLAMINE DERIVATIVES WITH HYDROXYETHYLAMINE PHARMACOPHORIC MOIETY AS MULTIFUNCTIONAL COMPOUNDS TARGETING CHOLINESTERASE, BETA-SECRETASE AND BETA-AMYLOID AGGREGATION.

Published in:

Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2017, v. 13, p. P280, doi. 10.1016/j.jalz.2017.06.171

By:

Malawska, Barbara;
Panek, Dawid;
Wieckowska, Anna;
Jonczyk, Jakub;
Godyn, Justyna;
Bajda, Marek;
Knez, Damijan;
Gobec, Stanislav

Publication type:

Article

Multifunctional, Fluorene‐Based Modulator of Cholinergic and GABAergic Neurotransmission as a Novel Drug Candidate for Palliative Treatment of Alzheimer's Disease.

Published in:

Angewandte Chemie, 2025, v. 137, n. 6, p. 1, doi. 10.1002/ange.202420510

By:

Panek, Dawid;
Pasieka, Anna;
Jończyk, Jakub;
Gawlińska, Milena;
Zaręba, Paula;
Siwek, Agata;
Wolak, Małgorzata;
Mordyl, Barbara;
Głuch‐Lutwin, Monika;
Latacz, Gniewomir;
Brazzolotto, Xavier;
Chantegreil, Fabien;
Nachon, Florian;
Zdarova Karasova, Jana;
Pejchal, Jaroslav;
Mzik, Martin;
Sestak, Vit;
Prchal, Lukas;
Odvarkova, Jitka;
Soukup, Ondrej

Publication type:

Article

Anti‐Alzheimer's multitarget‐directed ligands with serotonin 5‐HT<sub>6</sub> antagonist, butyrylcholinesterase inhibitory, and antioxidant activity.

Published in:

Archiv der Pharmazie, 2019, v. 352, n. 7, p. N.PAG, doi. 10.1002/ardp.201900041

By:

Marcinkowska, Monika;
Bucki, Adam;
Panek, Dawid;
Siwek, Agata;
Fajkis, Nikola;
Bednarski, Marek;
Zygmunt, Małgorzata;
Godyń, Justyna;
Del Rio Valdivieso, Alvaro;
Kotańska, Magdalena;
Kołaczkowski, Marcin;
Więckowska, Anna

Publication type:

Article

Connecting GSK-3β Inhibitory Activity with IKK-β or ROCK-1 Inhibition to Target Tau Aggregation and Neuroinflammation in Alzheimer's Disease—Discovery, In Vitro and In Cellulo Activity of Thiazole-Based Inhibitors.

Published in:

Molecules, 2024, v. 29, n. 11, p. 2616, doi. 10.3390/molecules29112616

By:

Góral, Izabella;
Wichur, Tomasz;
Sługocka, Emilia;
Godyń, Justyna;
Szałaj, Natalia;
Zaręba, Paula;
Głuch-Lutwin, Monika;
Mordyl, Barbara;
Panek, Dawid;
Więckowska, Anna

Publication type:

Article

Structure-Guided Design of N -Methylpropargylamino-Quinazoline Derivatives as Multipotent Agents for the Treatment of Alzheimer's Disease.

Published in:

International Journal of Molecular Sciences, 2023, v. 24, n. 11, p. 9124, doi. 10.3390/ijms24119124

By:

Svobodova, Barbora;
Pulkrabkova, Lenka;
Panek, Dawid;
Misiachna, Anna;
Kolcheva, Marharyta;
Andrys, Rudolf;
Handl, Jiri;
Capek, Jan;
Nyvltova, Pavlina;
Rousar, Tomas;
Prchal, Lukas;
Hepnarova, Vendula;
Hrabinova, Martina;
Muckova, Lubica;
Tosnerova, Daniela;
Karabanovich, Galina;
Finger, Vladimir;
Soukup, Ondrej;
Horak, Martin;
Korabecny, Jan

Publication type:

Article

Synthesis, Molecular Modelling and Biological Evaluation of Novel Heterodimeric, Multiple Ligands Targeting Cholinesterases and Amyloid Beta.

Published in:

Molecules, 2016, v. 21, n. 4, p. 410, doi. 10.3390/molecules21040410

By:

Hebda, Michalina;
Bajda, Marek;
Więckowska, Anna;
Szałaj, Natalia;
Pasieka, Anna;
Panek, Dawid;
Godyń, Justyna;
Wichur, Tomasz;
Knez, Damijan;
Gobec, Stanislav;
Malawska, Barbara

Publication type:

Article

MOLECULAR MODELING IN SEARCH OF NEW, MULTI-TARGET LIGANDS AGAINST ALZHEIMER'S DISEASE. EXPLORING THE BIOCHEMICAL MULTIVERSE.

Published in:

Military Medical Science Letters / Vojenské zdravotnické Listy, 2018, v. 87, p. 75

By:

Jończyk, Jakub;
Panek, Dawid;
Więckowska, Anna;
Godyń, Justyna;
Bajda, Marek;
Wichur, Tomasz;
Pasieka, Anna;
Knez, Damijan;
Pišlar, Anja;
Korabecny, Jan;
Soukup, Ondrej;
Sepsova, Vendula;
Sabaté, Raimon;
Kos, Janko;
Gobec, Stanislav;
Malawska, Barbara

Publication type:

Article