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Combination treatment strategy for pancreatic cancer involving the novel HDAC inhibitor MPT0E028 with a MEK inhibitor beyond K-Ras status.
- Published in:
- Clinical Epigenetics, 2019, v. 11, n. 1, p. N.PAG, doi. 10.1186/s13148-019-0681-6
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- Article
The anticancer effects of MPT0G211, a novel HDAC6 inhibitor, combined with chemotherapeutic agents in human acute leukemia cells.
- Published in:
- Clinical Epigenetics, 2018, v. 10, n. 1, p. N.PAG, doi. 10.1186/s13148-018-0595-8
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- Publication type:
- Article
Potential Effects of CXCL9 and CCL20 on Cardiac Fibrosis in Patients with Myocardial Infarction and Isoproterenol-Treated Rats.
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- Journal of Clinical Medicine, 2019, v. 8, n. 5, p. 659, doi. 10.3390/jcm8050659
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- Publication type:
- Article
Heteronemin, a Spongean Sesterterpene, Induces Cell Apoptosis and Autophagy in Human Renal Carcinoma Cells.
- Published in:
- BioMed Research International, 2015, v. 2015, p. 1, doi. 10.1155/2015/738241
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- Publication type:
- Article
Bradykinin-induced phosphoinositide hydrolysis and Ca2+ mobilization in canine cultured tracheal epithelial cells.
- Published in:
- 1999
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- Publication type:
- journal article
Lanatoside C, a cardiac glycoside, acts through protein kinase Cδ to cause apoptosis of human hepatocellular carcinoma cells.
- Published in:
- Scientific Reports, 2017, p. 46134, doi. 10.1038/srep46134
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- Publication type:
- Article
The apoptotic mechanisms of MT-6, a mitotic arrest inducer, in human ovarian cancer cells.
- Published in:
- Scientific Reports, 2017, p. 46149, doi. 10.1038/srep46149
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- Publication type:
- Article
MPT0G066, a novel anti-mitotic drug, induces JNK-independent mitotic arrest, JNK-mediated apoptosis, and potentiates antineoplastic effect of cisplatin in ovarian cancer.
- Published in:
- Scientific Reports, 2016, p. 31664, doi. 10.1038/srep31664
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- Publication type:
- Article
LTP-1, a novel antimitotic agent and Stat3 inhibitor, inhibits human pancreatic carcinomas in vitro and in vivo.
- Published in:
- Scientific Reports, 2016, p. 27794, doi. 10.1038/srep27794
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- Publication type:
- Article
MT-4 Suppresses Resistant Ovarian Cancer Growth through Targeting Tubulin and HSP27.
- Published in:
- PLoS ONE, 2015, v. 10, n. 4, p. 1, doi. 10.1371/journal.pone.0123819
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- Article
NPRL-Z-1, as a New Topoisomerase II Poison, Induces Cell Apoptosis and ROS Generation in Human Renal Carcinoma Cells.
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- PLoS ONE, 2014, v. 9, n. 11, p. 1, doi. 10.1371/journal.pone.0112220
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- Publication type:
- Article
Moscatilin inhibits migration and metastasis of human breast cancer MDA-MB-231 cells through inhibition of Akt and Twist signaling pathway.
- Published in:
- Journal of Molecular Medicine, 2013, v. 91, n. 3, p. 347, doi. 10.1007/s00109-012-0945-5
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- Publication type:
- Article
Gene Expression Signature-Based Approach Identifies Antifungal Drug Ciclopirox As a Novel Inhibitor of HMGA2 in Colorectal Cancer.
- Published in:
- Biomolecules (2218-273X), 2019, v. 9, n. 11, p. 688, doi. 10.3390/biom9110688
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- Publication type:
- Article
DYZ-2-90, a Novel Neo-tanshinlactone Ring-Opened Compound, Induces ERK-Mediated Mitotic Arrest and Subsequent Apoptosis by Activating JNK in Human Colorectal Cancer Cells.
- Published in:
- ChemBioChem, 2012, v. 13, n. 11, p. 1663, doi. 10.1002/cbic.201200191
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- Publication type:
- Article
Baicalein attenuates intimal hyperplasia after rat carotid balloon injury through arresting cell-cycle progression and inhibiting ERK, Akt, and NF-κB activity in vascular smooth-muscle cells.
- Published in:
- Naunyn-Schmiedeberg's Archives of Pharmacology, 2008, v. 378, n. 6, p. 579, doi. 10.1007/s00210-008-0328-1
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- Publication type:
- Article
Denbinobin induces apoptosis by apoptosis-inducing factor releasing and DNA damage in human colorectal cancer HCT-116 cells.
- Published in:
- Naunyn-Schmiedeberg's Archives of Pharmacology, 2008, v. 378, n. 5, p. 447, doi. 10.1007/s00210-008-0324-5
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- Publication type:
- Article
Elucidation of susceptible factors to endoplasmic reticulum stress-mediated anticancer activity in human hepatocellular carcinoma.
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- Naunyn-Schmiedeberg's Archives of Pharmacology, 2008, v. 377, n. 2, p. 167, doi. 10.1007/s00210-007-0249-4
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- Publication type:
- Article
The Protective Effect of Alstonia scholaris R. Br. on Hepatotoxin-induced Acute Liver Damage.
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- American Journal of Chinese Medicine, 1996, v. 24, n. 2, p. 153, doi. 10.1142/S0192415X96000207
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- Publication type:
- Article
Radiation-induced VEGF-C expression and endothelial cell proliferation in lung cancer.
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- Strahlentherapie und Onkologie, 2014, v. 190, n. 12, p. 1154, doi. 10.1007/s00066-014-0708-z
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- Publication type:
- Article
Radiation-induced VEGF-C expression and endothelial cell proliferation in lung cancer.
- Published in:
- 2014
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- Publication type:
- journal article
Depletion of 4E-BP1 and regulation of autophagy lead to YXM110-induced anticancer effects.
- Published in:
- Carcinogenesis, 2013, v. 34, n. 9, p. 2050, doi. 10.1093/carcin/bgt146
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- Publication type:
- Article
A site-moiety map and virtual screening approach for discovery of novel 5-LOX inhibitors.
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- Scientific Reports, 2020, v. 10, n. 1, p. 1, doi. 10.1038/s41598-020-67420-9
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- Publication type:
- Article
Investigating the potential effects of selective histone deacetylase 6 inhibitor ACY1215 on infarct size in rats with cardiac ischemia-reperfusion injury.
- Published in:
- BMC Pharmacology & Toxicology, 2020, v. 21, n. 1, p. 1, doi. 10.1186/s40360-020-0400-0
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- Publication type:
- Article
A Novel Dual HDAC6 and Tubulin Inhibitor, MPT0B451, Displays Anti-tumor Ability in Human Cancer Cells in Vitro and in Vivo.
- Published in:
- Frontiers in Pharmacology, 2018, p. 1, doi. 10.3389/fphar.2018.00205
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- Publication type:
- Article
MPT0G413, A Novel HDAC6-Selective Inhibitor, and Bortezomib Synergistically Exert Anti-tumor Activity in Multiple Myeloma Cells.
- Published in:
- Frontiers in Oncology, 2019, p. N.PAG, doi. 10.3389/fonc.2019.00249
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- Publication type:
- Article
Thrombin induces expression of twist and cell motility via the hypoxia-inducible factor-1α translational pathway in colorectal cancer cells.
- Published in:
- Journal of Cellular Physiology, 2011, v. 226, n. 4, p. 1060, doi. 10.1002/jcp.22428
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- Publication type:
- Article
In vitro and in vivo anti-tumour effects of MPT0B014, a novel derivative aroylquinoline, and in combination with erlotinib in human non-small-cell lung cancer cells.
- Published in:
- British Journal of Pharmacology, 2014, v. 171, n. 1, p. 122, doi. 10.1111/bph.12427
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- Publication type:
- Article
EGFL6 promotes colorectal cancer cell growth and mobility and the anti‐cancer property of anti-EGFL6 antibody.
- Published in:
- Cell & Bioscience, 2021, v. 11, n. 1, p. 1, doi. 10.1186/s13578-021-00561-0
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- Publication type:
- Article
Astragalus membranaceus–Derived Anti-Programmed Death-1 Monoclonal Antibodies with Immunomodulatory Therapeutic Effects against Tumors.
- Published in:
- BioMed Research International, 2020, p. 1, doi. 10.1155/2020/3415471
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- Publication type:
- Article
Anticancer Study of a Novel Pan-HDAC Inhibitor MPT0G236 in Colorectal Cancer Cells.
- Published in:
- International Journal of Molecular Sciences, 2023, v. 24, n. 16, p. 12588, doi. 10.3390/ijms241612588
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- Publication type:
- Article
QS-ZYX-1-61 induces apoptosis through topoisomerase II in human non-small-cell lung cancer A549 cells.
- Published in:
- Cancer Science, 2012, v. 103, n. 1, p. 80, doi. 10.1111/j.1349-7006.2011.02103.x
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- Publication type:
- Article
A novel dual HDAC and HSP90 inhibitor, MPT0G449, downregulates oncogenic pathways in human acute leukemia in vitro and in vivo.
- Published in:
- Oncogenesis, 2021, v. 10, n. 5, p. 1, doi. 10.1038/s41389-021-00331-0
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- Publication type:
- Article
An ensemble machine learning model generates a focused screening library for the identification of CDK8 inhibitors.
- Published in:
- Protein Science: A Publication of the Protein Society, 2024, v. 33, n. 6, p. 1, doi. 10.1002/pro.5007
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- Article
In silico identification of a novel Cdc2‐like kinase 2 (CLK2) inhibitor in triple negative breast cancer.
- Published in:
- Protein Science: A Publication of the Protein Society, 2024, v. 33, n. 6, p. 1, doi. 10.1002/pro.5004
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- Publication type:
- Article