Works matching AU Pan, Jingxuan

Results: 47

PRMT1 Promotes the Self‐renewal of Leukemia Stem Cells by Regulating Protein Synthesis.

Published in:

Advanced Science, 2025, v. 12, n. 5, p. 1, doi. 10.1002/advs.202308586

By:

Zhou, Min;
Huang, Yi;
Xu, Ping;
Li, Shuyi;
Duan, Chen;
Lin, Xiaoying;
Bao, Shilai;
Zou, Waiyi;
Pan, Jingxuan;
Liu, Chang;
Jin, Yanli

Publication type:

Article

PRMT1 Promotes the Self‐renewal of Leukemia Stem Cells by Regulating Protein Synthesis.

Published in:

Advanced Science, 2025, v. 12, n. 5, p. 1, doi. 10.1002/advs.202308586

By:

Zhou, Min;
Huang, Yi;
Xu, Ping;
Li, Shuyi;
Duan, Chen;
Lin, Xiaoying;
Bao, Shilai;
Zou, Waiyi;
Pan, Jingxuan;
Liu, Chang;
Jin, Yanli

Publication type:

Article

Anthelmintic pyrvinium pamoate blocks Wnt/β-catenin and induces apoptosis in multiple myeloma cells.

Published in:

Oncology Letters, 2018, v. 15, n. 4, p. 5871, doi. 10.3892/ol.2018.8006

By:

Xu, Fang;
Zhu, Yingjie;
Lu, Yuhong;
Yu, Zhi;
Zhong, Jun;
Li, Yangqiu;
Pan, Jingxuan

Publication type:

Article

Anthelmintic niclosamide suppresses transcription of BCR-ABL fusion oncogene via disabling Sp1 and induces apoptosis in imatinib-resistant CML cells harboring T315I mutant.

Published in:

Cell Death & Disease, 2018, v. 9, n. 2, p. 1, doi. 10.1038/s41419-017-0075-7

By:

Jin, Bei;
Wang, Chengyan;
Shen, Yingying;
Pan, Jingxuan

Publication type:

Article

Combination chemotherapy including combretastatin A4 phosphate and paclitaxel is effective against anaplastic thyroid cancer in a nude mouse xenograft model.

Published in:

2007

By:

Yeung, Sai-Ching J;
She, Miaorong;
Yang, Huiling;
Pan, Jingxuan;
Sun, Lily;
Chaplin, David

Publication type:

journal article

Bcl-2-associated X protein is the main mediator of manumycin a-induced apoptosis in anaplastic thyroid cancer cells.

Published in:

2005

By:

Pan, Jingxuan;
Huang, Huizhi;
Sun, Lily;
Fang, Bingliang;
Yeung, Sai-Ching Jim

Publication type:

journal article

Cytochrome c release is upstream to activation of caspase-9, caspase-8, and caspase-3 in the enhanced apoptosis of anaplastic thyroid cancer cells induced by manumycin and paclitaxel.

Published in:

2001

By:

JINGXUAN PAN;
GUANGPU X;
SAI-CHING JIM YEUNG

Publication type:

journal article

Angiogenesis Inhibition in the in Vivo Antineoplastic Effect of Manumycin and Paclitaxel against Anaplastic Thyroid Carcinoma.

Published in:

2001

By:

GUANGPU XU;
JINGXUAN PAN;
MARTIN, CHARLES;
SAI-CHING JIM YEUNG

Publication type:

journal article

Tenovin-6-mediated inhibition of SIRT1/2 induces apoptosis in acute lymphoblastic leukemia (ALL) cells and eliminates ALL stem/progenitor cells.

Published in:

BMC Cancer, 2015, v. 15, n. 1, p. 1, doi. 10.1186/s12885-015-1282-1

By:

Yanli Jin;
Qi Cao;
Chun Chen;
Xin Du;
Bei Jin;
Jingxuan Pan

Publication type:

Article

Correction to: Pristimerin induces apoptosis in imatinib-resistant chronic myelogenous leukemia cells harboring T315I mutation by blocking NF-κB signaling and depleting Bcr-Abl.

Published in:

2021

By:

Lu, Zhongzheng;
Jin, Yanli;
Chen, Chun;
Li, Juan;
Cao, Qi;
Pan, Jingxuan

Publication type:

Correction Notice

Correction to: Ponatinib efficiently kills imatinib-resistant chronic eosinophilic leukemia cells harboring gatekeeper mutant T674I FIP1L1-PDGFRα: roles of Mcl-1 and β-catenin.

Published in:

2021

By:

Jin, Yanli;
Ding, Ke;
Li, Honglin;
Xue, Mengzhu;
Shi, Xiaoke;
Wang, Chengyan;
Pan, Jingxuan

Publication type:

Correction Notice

Correction to: Transcriptional inhibition by CDK7/9 inhibitor SNS-032 abrogates oncogene addiction and reduces liver metastasis in uveal melanoma.

Published in:

2021

By:

Zhang, Jing;
Liu, Shenglan;
Ye, Qianyun;
Pan, Jingxuan

Publication type:

Correction Notice

CHEK1 and circCHEK1_246aa evoke chromosomal instability and induce bone lesion formation in multiple myeloma.

Published in:

Molecular Cancer, 2021, v. 20, n. 1, p. 1, doi. 10.1186/s12943-021-01380-0

By:

Gu, Chunyan;
Wang, Wang;
Tang, Xiaozhu;
Xu, Tingting;
Zhang, Yanxin;
Guo, Mengjie;
Wei, Rongfang;
Wang, Yajun;
Jurczyszyn, Artur;
Janz, Siegfried;
Beksac, Meral;
Zhan, Fenghuang;
Seckinger, Anja;
Hose, Dirk;
Pan, Jingxuan;
Yang, Ye

Publication type:

Article

Le bilboquet, un badinage dangereux ? Une étude sur Le Bilboquet de Marivaux.

Published in:

Quetes Litteraires, 2023, p. 48, doi. 10.31743/ql.16858

By:

Jingxuan Pan

Publication type:

Article

Antitumor activity of niclosamide-mediated oxidative stress against acute lymphoblastic leukemia.

Published in:

Carcinogenesis, 2024, v. 45, n. 12, p. 940, doi. 10.1093/carcin/bgae035

By:

Yang, Jing;
Liu, Yong;
Du, Zefan;
Zhou, Qin;
Yang, Luo;
Ye, Qianyun;
Pan, Jingxuan;
Zou, Waiyi;
Chen, Chun;
Jin, Bei

Publication type:

Article

Functional Characterization of D9, a Novel Deazaneplanocin A (DZNep) Analog, in Targeting Acute Myeloid Leukemia (AML).

Published in:

PLoS ONE, 2015, v. 10, n. 4, p. 1, doi. 10.1371/journal.pone.0122983

By:

Jiang, Xia;
Lim, Cheryl Zi Hui;
Li, Zhimei;
Lee, Puay Leng;
Yatim, Siti Maryam J. M.;
Guan, Peiyong;
Li, Juntao;
Zhou, Jianbiao;
Pan, Jingxuan;
Chng, Wee-Joo;
Chai, Christina L. L.;
Yu, Qiang

Publication type:

Article

The Conformational Control Inhibitor of Tyrosine Kinases DCC-2036 Is Effective for Imatinib-Resistant Cells Expressing T674I FIP1L1-PDGFRα.

Published in:

PLoS ONE, 2013, v. 8, n. 8, p. 1, doi. 10.1371/journal.pone.0073059

By:

Shen, Yingying;
Shi, Xiaoke;
Pan, Jingxuan

Publication type:

Article

Correction to: Salinomycin effectively eliminates cancer stem-like cells and obviates hepatic metastasis in uveal melanoma.

Published in:

2021

By:

Zhou, Jingfeng;
Liu, Shenglan;
Wang, Yun;
Dai, Wei;
Zou, Hailin;
Wang, Shubo;
Zhang, Jing;
Pan, Jingxuan

Publication type:

Correction Notice

Verification of EZH2 as a druggable target in metastatic uveal melanoma.

Published in:

Molecular Cancer, 2020, v. 19, n. 1, p. 1, doi. 10.1186/s12943-020-01173-x

By:

Jin, Bei;
Zhang, Ping;
Zou, Hailin;
Ye, Huijing;
Wang, Yun;
Zhang, Jing;
Yang, Huasheng;
Pan, Jingxuan

Publication type:

Article

Salinomycin effectively eliminates cancer stem-like cells and obviates hepatic metastasis in uveal melanoma.

Published in:

Molecular Cancer, 2019, v. 18, n. 1, p. 1, doi. 10.1186/s12943-019-1068-1

By:

Zhou, Jingfeng;
Liu, Shenglan;
Wang, Yun;
Dai, Wei;
Zou, Hailin;
Wang, Shubo;
Zhang, Jing;
Pan, Jingxuan

Publication type:

Article

Transcriptional inhibition by CDK7/9 inhibitor SNS-032 abrogates oncogene addiction and reduces liver metastasis in uveal melanoma.

Published in:

Molecular Cancer, 2019, v. 18, n. 1, p. N.PAG, doi. 10.1186/s12943-019-1070-7

By:

Zhang, Jing;
Liu, Shenglan;
Ye, Qianyun;
Pan, Jingxuan

Publication type:

Article

GCNT2 induces epithelial‐mesenchymal transition and promotes migration and invasion in esophageal squamous cell carcinoma cells.

Published in:

Cell Biochemistry & Function, 2019, v. 37, n. 1, p. 42, doi. 10.1002/cbf.3371

By:

Peng, Fei;
He, Qi;
Cheng, Chao;
Pan, Jingxuan

Publication type:

Article

Pristimerin targeting NF‐κB pathway inhibits proliferation, migration, and invasion in esophageal squamous cell carcinoma cells.

Published in:

Cell Biochemistry & Function, 2018, v. 36, n. 4, p. 228, doi. 10.1002/cbf.3335

By:

Tu, Yuanqing;
Tan, Fuxing;
Zhou, Jingfeng;
Pan, Jingxuan

Publication type:

Article

Dual cyclin-dependent kinase 4/6 inhibition by PD-0332991 induces apoptosis and senescence in oesophageal squamous cell carcinoma cells.

Published in:

2017

By:

Chen, Liang;
Pan, Jingxuan

Publication type:

journal article

Super-enhancer landscape reveals leukemia stem cell reliance on X-box binding protein 1 as a therapeutic vulnerability.

Published in:

Science Translational Medicine, 2021, v. 13, n. 612, p. 1, doi. 10.1126/scitranslmed.abh3462

By:

Zhou, Jingfeng;
Wang, Shubo;
Nie, Danian;
Lai, Peilong;
Li, Yiqing;
Li, Yangqiu;
Jin, Yanli;
Pan, Jingxuan

Publication type:

Article

SAHA and S116836, a novel tyrosine kinase inhibitor, synergistically induce apoptosis in imatinib-resistant chronic myelogenous leukemia cells.

Published in:

Cancer Biology & Therapy, 2014, v. 15, n. 7, p. 951, doi. 10.4161/cbt.28931

By:

Qiangui Bu;
Lijing Cui;
Juan Li;
Xin Du;
Waiyi Zou;
Ke Ding;
Jingxuan Pan

Publication type:

Article

PQJS380.

Published in:

Cancer Biology & Therapy, 2014, v. 15, n. 1, p. 119, doi. 10.4161/cbt.27145

By:

Xiaohui Zhu;
Li Chen;
Sheng Jiang;
Chun Chen;
Yiwu Yao;
Dong Chen;
Hongman Xue;
Jingxuan Pan

Publication type:

Article

GDP366, a novel small molecule dual inhibitor of survivin and Op18, induces cell growth inhibition, cellular senescence and mitotic catastrophe in human cancer cells.

Published in:

Cancer Biology & Therapy, 2010, v. 9, n. 8, p. 640, doi. 10.4161/cbt.9.8.11269

By:

Xianping Shi;
Deping Wang;
Ke Ding;
Zhongzheng Lu;
Yanli Jin;
Jin Zhang;
Jingxuan Pan

Publication type:

Article

Triptolide abrogates oncogene FIP1L1-PDGFRα addiction and induces apoptosis in hypereosinophilic syndrome.

Published in:

Cancer Science, 2009, v. 100, n. 11, p. 2210, doi. 10.1111/j.1349-7006.2009.01283.x

By:

Jin, Yanli;
Chen, Qi;
Lu, Zhongzheng;
Chen, Bo;
Pan, Jingxuan

Publication type:

Article

Activity of triptolide against human mast cells harboring the kinase domain mutant KIT.

Published in:

Cancer Science, 2009, v. 100, n. 7, p. 1335, doi. 10.1111/j.1349-7006.2009.01159.x

By:

Jin, Yanli;
Chen, Qi;
Shi, Xianping;
Lu, Zhongzheng;
Cheng, Chao;
Lai, Yingrong;
Zheng, Qin;
Pan, Jingxuan

Publication type:

Article

Sensitivity of human cells bearing oncogenic mutant kit isoforms to the novel tyrosine kinase inhibitor INNO-406.

Published in:

Cancer Science, 2007, v. 98, n. 8, p. 1223, doi. 10.1111/j.1349-7006.2007.00516.x

By:

Pan, Jingxuan;
Quintás-Cardama, Alfonso;
Manshouri, Taghi;
Cortes, Jorge;
Kantarjian, Hagop;
Verstovsek, Srdan

Publication type:

Article

CHK1 targets spleen tyrosine kinase (L) for proteolysis in hepatocellular carcinoma.

Published in:

Journal of Clinical Investigation, 2012, v. 122, n. 6, p. 2165, doi. 10.1172/JCI61380

By:

Jian Hong;
Kaishun Hu;
Yunfei Yuan;
Yi Sang;
Qiangui Bu;
Guihua Chen;
Longjun Yang;
Binkui Li;
Pinzhu Huang;
Dongtai Chen;
Yi Liang;
Ruhua Zhang;
Jingxuan Pan;
Yi-Xin Zeng;
Tiebang Kang

Publication type:

Article

Class III-specific HDAC inhibitor Tenovin-6 induces apoptosis, suppresses migration and eliminates cancer stem cells in uveal melanoma.

Published in:

Scientific Reports, 2016, p. 22622, doi. 10.1038/srep22622

By:

Dai, Wei;
Zhou, Jingfeng;
Jin, Bei;
Pan, Jingxuan

Publication type:

Article

Differential impact of structurally different anti-diabetic drugs on proliferation and chemosensitivity of acute lymphoblastic leukemia cells.

Published in:

Cell Cycle, 2012, v. 11, n. 12, p. 2314, doi. 10.4161/cc.20770

By:

Jingxuan Pan;
Chun Chen;
Yanli Jin;
Fuentes-Mattei, Enrique;
Velazquez-Tores, Guermarie;
Benito, Juliana Maria;
Konopleva, Marina;
Andreeff, Michael;
Mong-Hong Lee;
Sai-Ching Jim Yeung

Publication type:

Article

Everolimus enhances the cytotoxicity of bendamustine in multiple myeloma cells through a network of pro-apoptotic and cell-cycle-progression regulatory proteins.

Published in:

Acta Biochimica et Biophysica Sinica, 2013, v. 45, n. 8, p. 683, doi. 10.1093/abbs/gmt054

By:

Lu, Bo;
Li, Juan;
Pan, Jingxuan;
Huang, Beihui;
Liu, Junru;
Zheng, Dong

Publication type:

Article

Targeting methyltransferase PRMT5 eliminates leukemia stem cells in chronic myelogenous leukemia.

Published in:

2016

By:

Yanli Jin;
Jingfeng Zhou;
Fang Xu;
Bei Jin;
Lijing Cui;
Yun Wang;
Xin Du;
Juan Li;
Peng Li;
Ruibao Ren;
Jingxuan Pan;
Jin, Yanli;
Zhou, Jingfeng;
Xu, Fang;
Jin, Bei;
Cui, Lijing;
Wang, Yun;
Du, Xin;
Li, Juan;
Li, Peng

Publication type:

journal article

Inhibitory effect of the anthelmintic drug pyrvinium pamoate on T315I BCR-ABL-positive CML cells.

Published in:

Molecular Medicine Reports, 2017, v. 16, n. 6, p. 9217, doi. 10.3892/mmr.2017.7685

By:

JING ZHANG;
YANLI JIN;
JINGXUAN PAN

Publication type:

Article

Cytokine-induced apoptosis inhibitor 1 inhibits the growth and proliferation of multiple myeloma.

Published in:

Molecular Medicine Reports, 2015, v. 12, n. 2, p. 2056, doi. 10.3892/mmr.2015.3656

By:

XIAOBO WANG;
JINGXUAN PAN;
JUAN LI

Publication type:

Article

Inhibitory effect of pyrvinium pamoate on uveal melanoma cells involves blocking of Wnt/β-catenin pathway.

Published in:

Acta Biochimica et Biophysica Sinica, 2017, v. 49, n. 10, p. 890, doi. 10.1093/abbs/gmx089

By:

Lei Zheng;
Yizhi Liu;
Jingxuan Pan

Publication type:

Article

Consensus statement on extracellular vesicles in liquid biopsy for advancing laboratory medicine.

Published in:

Clinical Chemistry & Laboratory Medicine, 2025, v. 63, n. 3, p. 465, doi. 10.1515/cclm-2024-0188

By:

Dong, Xingli;
Lin, Yusheng;
Li, Kai;
Liang, Gaofeng;
Huang, Xiaoyi;
Pan, Jingxuan;
Wang, Lu;
Zhang, Dongmei;
Liu, Tingjiao;
Wang, Tong;
Yan, Xiaomei;
Zhang, Long;
Li, Xiaowu;
Qu, Xiujuan;
Jia, Da;
Li, Yong;
Zhang, Hao

Publication type:

Article

Ponatinib efficiently kills imatinib-resistant chronic eosinophilic leukemia cells harboring gatekeeper mutant T674I FIP1L1-PDGFRα: roles of Mcl-1 and β-catenin.

Published in:

Molecular Cancer, 2014, v. 13, n. 1, p. 1, doi. 10.1186/1476-4598-13-17

By:

Yanli Jin;
Ke Ding;
Honglin Li;
Mengzhu Xue;
Xiaoke Shi;
Chengyan Wang;
Jingxuan Pan

Publication type:

Article

Pristimerin induces apoptosis in imatinib-resistantchronic myelogenous leukemia cells harboringT315I mutation by blocking NF-κB signaling anddepleting Bcr-Abl.

Published in:

Molecular Cancer, 2010, v. 9, p. 112, doi. 10.1186/1476-4598-9-112

By:

Zhongzheng Lu;
Yanli Jin;
Chun Chen;
Juan Li;
Qi Cao;
Jingxuan Pan

Publication type:

Article

Pristimerin effectively inhibits the malignant phenotypes of uveal melanoma cells by targeting NF-κB pathway.

Published in:

International Journal of Oncology, 2017, v. 51, n. 3, p. 887, doi. 10.3892/ijo.2017.4079

By:

BIAO ZHANG;
JING ZHANG;
JINGXUAN PAN

Publication type:

Article

Overcoming Gleevec-resistance by blocking oncogene addiction in malignant hematologic cells.

Published in:

2012

By:

Pan, Jingxuan

Publication type:

Abstract

Cellular mechanisms of combining innate immunity activation with PD-1/PD-L1 blockade in treatment of colorectal cancer.

Published in:

Molecular Cancer, 2024, v. 23, n. 1, p. 1, doi. 10.1186/s12943-024-02166-w

By:

Xie, Qi;
Liu, Xiaolin;
Liu, Rengyun;
Pan, Jingxuan;
Liang, Jing

Publication type:

Article

Effects of super-enhancers in cancer metastasis: mechanisms and therapeutic targets.

Published in:

Molecular Cancer, 2024, v. 23, n. 1, p. 1, doi. 10.1186/s12943-024-02033-8

By:

Liu, Shenglan;
Dai, Wei;
Jin, Bei;
Jiang, Feng;
Huang, Hao;
Hou, Wen;
Lan, Jinxia;
Jin, Yanli;
Peng, Weijie;
Pan, Jingxuan

Publication type:

Article

Activation of transmembrane receptor tyrosine kinase DDR1-STAT3 cascade by extracellular matrix remodeling promotes liver metastatic colonization in uveal melanoma.

Published in:

Signal Transduction & Targeted Therapy, 2021, v. 6, n. 1, p. 1, doi. 10.1038/s41392-021-00563-x

By:

Dai, Wei;
Liu, Shenglan;
Wang, Shubo;
Zhao, Li;
Yang, Xiao;
Zhou, Jingfeng;
Wang, Yun;
Zhang, Jing;
Zhang, Ping;
Ding, Ke;
Li, Yangqiu;
Pan, Jingxuan

Publication type:

Article