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A short story on how chromophore is hydrolyzed from rhodopsin for recycling.
- Published in:
- BioEssays, 2023, v. 45, n. 9, p. 1, doi. 10.1002/bies.202300068
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- Publication type:
- Article
Structural basis for the allosteric modulation of rhodopsin by nanobody binding to its extracellular domain.
- Published in:
- Nature Communications, 2023, v. 14, n. 1, p. 1, doi. 10.1038/s41467-023-40911-9
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- Publication type:
- Article
Genome editing in the treatment of ocular diseases.
- Published in:
- Experimental & Molecular Medicine EMM, 2023, v. 55, n. 8, p. 1678, doi. 10.1038/s12276-023-01057-2
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- Publication type:
- Article
NEW APPROACH FOR DELIVERY OF GENE THERAPY TO CONES, USING MODIFIED RABIES VIRUS.
- Published in:
- Acta Neurobiologiae Experimentalis, 2023, v. 83, p. CXXIV
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- Publication type:
- Article
Investigating the Role of Rhodopsin F45L Mutation in Mouse Rod Photoreceptor Signaling and Survival.
- Published in:
- eNeuro, 2023, v. 10, n. 3, p. 1, doi. 10.1523/ENEURO.0330-22.2023
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- Publication type:
- Article
In vivo base editing rescues cone photoreceptors in a mouse model of early-onset inherited retinal degeneration.
- Published in:
- Nature Communications, 2022, v. 13, n. 1, p. 1, doi. 10.1038/s41467-022-29490-3
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- Publication type:
- Article
Stabilization of Meta‐I Rhodopsin Conformation by a Nanobody.
- Published in:
- FASEB Journal, 2022, v. 36, p. N.PAG, doi. 10.1096/fasebj.2022.36.S1.R2572
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- Publication type:
- Article
Visual System Hyperexcitability and Compromised V1 Receptive Field Properties in Early-Stage Retinitis Pigmentosa inMice.
- Published in:
- eNeuro, 2022, v. 9, n. 3, p. 1, doi. 10.1523/ENEURO.0107-22.2022
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- Publication type:
- Article
Regenerating Skeletal Muscle Compensates for the Impaired Macrophage Functions Leading to Normal Muscle Repair in Retinol Saturase Null Mice.
- Published in:
- Cells (2073-4409), 2022, v. 11, n. 8, p. 1333, doi. 10.3390/cells11081333
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- Publication type:
- Article
large animal model of RDH5-associated retinopathy recapitulates important features of the human phenotype.
- Published in:
- Human Molecular Genetics, 2022, v. 31, n. 8, p. 1263, doi. 10.1093/hmg/ddab316
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- Publication type:
- Article
In vivo base editing rescues cone photoreceptors in a mouse model of early-onset inherited retinal degeneration.
- Published in:
- Nature Communications, 2022, v. 13, n. 1, p. 1, doi. 10.1038/s41467-022-29490-3
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- Publication type:
- Article
Determinants shaping the nanoscale architecture of the mouse rod outer segment.
- Published in:
- eLife, 2022, p. 1, doi. 10.7554/eLife.72817
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- Publication type:
- Article
VCP/p97 inhibitor CB-5083 modulates muscle pathology in a mouse model of VCP inclusion body myopathy.
- Published in:
- 2022
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- Publication type:
- journal article
Straightforward Access to Terminally Disubstituted Electron‐Deficient Alkylidene Cyclopent‐2‐en‐4‐ones through Olefination with α‐Carbonyl and α‐Cyano Secondary Alkyl Sulfones.
- Published in:
- European Journal of Organic Chemistry, 2021, v. 2021, n. 48, p. 6725, doi. 10.1002/ejoc.202101258
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- Publication type:
- Article
How to Apply Fuzzy MISO PID in the Industry? An Empirical Study Case on Simulation of Crane Relocating Containers.
- Published in:
- 2020
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- Publication type:
- Letter
Homeostatic plasticity in the retina is associated with maintenance of night vision during retinal degenerative disease.
- Published in:
- eLife, 2020, p. 1, doi. 10.7554/eLife.59422
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- Publication type:
- Article
Single particle cryo‐EM of the complex between interphotoreceptor retinoid‐binding protein and a monoclonal antibody.
- Published in:
- FASEB Journal, 2020, v. 34, n. 10, p. 13918, doi. 10.1096/fj.202000796RR
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- Publication type:
- Article
Epigenetic hallmarks of age-related macular degeneration are recapitulated in a photosensitive mouse model.
- Published in:
- Human Molecular Genetics, 2020, v. 29, n. 15, p. 2611, doi. 10.1093/hmg/ddaa158
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- Publication type:
- Article
Melanopsin Carboxy-terminus phosphorylation plasticity and bulk negative charge, not strict site specificity, achieves phototransduction deactivation.
- Published in:
- PLoS ONE, 2020, v. 15, n. 4, p. 1, doi. 10.1371/journal.pone.0228121
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- Publication type:
- Article
Retinol Saturase Knock-Out Mice are Characterized by Impaired Clearance of Apoptotic Cells and Develop Mild Autoimmunity.
- Published in:
- Biomolecules (2218-273X), 2019, v. 9, n. 11, p. 737, doi. 10.3390/biom9110737
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- Publication type:
- Article
Stereospecific modulation of dimeric rhodopsin.
- Published in:
- FASEB Journal, 2019, v. 33, n. 8, p. 9526, doi. 10.1096/fj.201900443RR
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- Publication type:
- Article
Multicriteria Approach to Sustainable Transport Evaluation under Incomplete Knowledge: Electric Bikes Case Study.
- Published in:
- Sustainability (2071-1050), 2019, v. 11, n. 12, p. 3314, doi. 10.3390/su11123314
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- Publication type:
- Article
Retinal Gene Distribution and Functionality Implicated in Inherited Retinal Degenerations Can Reveal Disease-Relevant Pathways for Pharmacologic Intervention.
- Published in:
- Pharmaceuticals (14248247), 2019, v. 12, n. 2, p. 74, doi. 10.3390/ph12020074
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- Publication type:
- Article
Conditional deletion of Des1 in the mouse retina does not impair the visual cycle in cones.
- Published in:
- FASEB Journal, 2019, v. 33, n. 4, p. 5782, doi. 10.1096/fj.201802493R
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- Publication type:
- Article
Apo-Opsin Exists in Equilibrium Between a Predominant Inactive and a Rare Highly Active State.
- Published in:
- Journal of Neuroscience, 2019, v. 39, n. 2, p. 212, doi. 10.1523/JNEUROSCI.1980-18.2018
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- Publication type:
- Article
Structural biology of 11-cis-retinaldehyde production in the classical visual cycle.
- Published in:
- Biochemical Journal, 2018, v. 475, n. 20, p. 3171, doi. 10.1042/BCJ20180193
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- Publication type:
- Article
Insights into the pathogenesis of dominant retinitis pigmentosa associated with a D477G mutation in RPE65.
- Published in:
- Human Molecular Genetics, 2018, v. 27, n. 13, p. 2225, doi. 10.1093/hmg/ddy128
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- Publication type:
- Article
New GABA modulators protect photoreceptor cells from light-induced degeneration in mouse models.
- Published in:
- FASEB Journal, 2018, v. 32, n. 6, p. 3289, doi. 10.1096/fj.201701250R
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- Publication type:
- Article
Targeting G protein-coupled receptor signaling at the G protein level with a selective nanobody inhibitor.
- Published in:
- Nature Communications, 2018, v. 9, n. 1, p. 1, doi. 10.1038/s41467-018-04432-0
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- Publication type:
- Article
A novel small molecule chaperone of rod opsin and its potential therapy for retinal degeneration.
- Published in:
- Nature Communications, 2018, v. 9, n. 1, p. 1, doi. 10.1038/s41467-018-04261-1
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- Publication type:
- Article
Crowd sourcing difficult problems in protein science<sup>*</sup>.
- Published in:
- Protein Science: A Publication of the Protein Society, 2017, v. 26, n. 11, p. 2118, doi. 10.1002/pro.3247
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- Publication type:
- Article
Photoreceptor cells produce inflammatory products that contribute to retinal vascular permeability in a mouse model of diabetes.
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- Diabetologia, 2017, v. 60, n. 10, p. 2111, doi. 10.1007/s00125-017-4381-5
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- Publication type:
- Article
Rescue of mutant rhodopsin traffic by metformin-induced AMPK activation accelerates photoreceptor degeneration.
- Published in:
- Human Molecular Genetics, 2017, v. 26, n. 2, p. 305, doi. 10.1093/hmg/ddw387
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- Publication type:
- Article
Dynamic peptides of human TPP1 fulfill diverse functions in telomere maintenance.
- Published in:
- Nucleic Acids Research, 2016, v. 44, n. 21, p. 10467, doi. 10.1093/nar/gkw846
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- Publication type:
- Article
Transcriptome analysis reveals rod/cone photoreceptor specific signatures across mammalian retinas.
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- Human Molecular Genetics, 2016, v. 25, n. 20, p. 4376, doi. 10.1093/hmg/ddw268
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- Publication type:
- Article
The Molecular Mechanism of P2Y<sub>1</sub> Receptor Activation.
- Published in:
- Angewandte Chemie, 2016, v. 128, n. 35, p. 10487, doi. 10.1002/ange.201605147
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- Publication type:
- Article
The Molecular Mechanism of P2Y<sub>1</sub> Receptor Activation.
- Published in:
- Angewandte Chemie International Edition, 2016, v. 55, n. 35, p. 10331, doi. 10.1002/anie.201605147
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- Publication type:
- Article
Synergistically acting agonists and antagonists of G protein-coupled receptors prevent photoreceptor cell degeneration.
- Published in:
- Science Signaling, 2016, v. 9, n. 438, p. 1, doi. 10.1126/scisignal.aag0245
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- Publication type:
- Article
Mechanistic Studies on the Stereoselectivity of the Serotonin 5-HT<sub>1A</sub> Receptor.
- Published in:
- Angewandte Chemie, 2016, v. 128, n. 30, p. 8803, doi. 10.1002/ange.201603766
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- Publication type:
- Article
Mechanistic Studies on the Stereoselectivity of the Serotonin 5-HT<sub>1A</sub> Receptor.
- Published in:
- Angewandte Chemie International Edition, 2016, v. 55, n. 30, p. 8661, doi. 10.1002/anie.201603766
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- Publication type:
- Article
Dominant and recessive mutations in rhodopsin activate different cell death pathways.
- Published in:
- Human Molecular Genetics, 2016, v. 25, n. 13, p. 2801, doi. 10.1093/hmg/ddw137
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- Publication type:
- Article
The impact of microRNA gene regulation on the survival and function of mature cell types in the eye.
- Published in:
- FASEB Journal, 2016, v. 30, n. 1, p. 23, doi. 10.1096/fj.15-279745
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- Publication type:
- Article
Self-Assembly of a Multifunctional Lipid With Core-Shell Dendrimer DNA Nanoparticles Enhanced Efficient Gene Delivery at Low Charge Ratios into RPE Cells.
- Published in:
- Macromolecular Bioscience, 2015, v. 15, n. 12, p. 1663, doi. 10.1002/mabi.201500192
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- Publication type:
- Article
Retinol dehydrogenase 8 and ATP-binding cassette transporter 4 modulate dark adaptation of M-cones in mammalian retina.
- Published in:
- Journal of Physiology, 2015, v. 593, n. 22, p. 4923, doi. 10.1113/JP271285
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- Publication type:
- Article
Serum levels of lipid metabolites in age-related macular degeneration.
- Published in:
- FASEB Journal, 2015, v. 29, n. 11, p. 4579, doi. 10.1096/fj.15-275289
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- Publication type:
- Article
Robust Endoplasmic Reticulum-Associated Degradation of Rhodopsin Precedes Retinal Degeneration.
- Published in:
- Molecular Neurobiology, 2015, v. 52, n. 1, p. 679, doi. 10.1007/s12035-014-8881-8
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- Publication type:
- Article
Molecular pharmacodynamics of emixustat in protection against retinal degeneration.
- Published in:
- Journal of Clinical Investigation, 2015, v. 125, n. 7, p. 2781, doi. 10.1172/JCI80950
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- Publication type:
- Article
The Mechanism of Ligand-Induced Activation or Inhibition of μ- and κ-Opioid Receptors.
- Published in:
- Angewandte Chemie, 2015, v. 127, n. 26, p. 7670, doi. 10.1002/ange.201501742
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- Publication type:
- Article
The Mechanism of Ligand-Induced Activation or Inhibition of μ- and κ-Opioid Receptors.
- Published in:
- Angewandte Chemie International Edition, 2015, v. 54, n. 26, p. 7560, doi. 10.1002/anie.201501742
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- Publication type:
- Article
Protein misfolding and the pathogenesis of ABCA4-associated retinal degenerations.
- Published in:
- Human Molecular Genetics, 2015, v. 24, n. 11, p. 3220, doi. 10.1093/hmg/ddv073
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- Publication type:
- Article