Works by Pae, Ae

Results: 61

Stereochemical control in diastereoselective reduction of α-substituted-β-ketoesters using a reductase purified from Kluyveromyces marxianus.

Published in:

Biotechnology Letters, 2002, v. 24, n. 20, p. 1695, doi. 10.1023/A:1020649316546

By:

Cha, Joo Hwan;
Pae, Ae Nim;
Choi, Kyung Il;
Cho, Yong Seo;
Kim, Wook Hyun;
Han, Ye Sun;
Yun, Hong-Chul;
Lee, Jongsoo;
Koh, Hun Yeong;
Lee, Eun

Publication type:

Article

Marine polyphenol phlorotannins promote non-rapid eye movement sleep in mice via the benzodiazepine site of the GABA receptor.

Published in:

Psychopharmacology, 2014, v. 231, n. 14, p. 2825, doi. 10.1007/s00213-014-3445-1

By:

Cho, Suengmok;
Yoon, Minseok;
Pae, Ae;
Jin, Young-Ho;
Cho, Nam-Chul;
Takata, Yohko;
Urade, Yoshihiro;
Kim, Sojin;
Kim, Jin-Soo;
Yang, Hyejin;
Kim, Jiyoung;
Kim, Jinkyoung;
Han, Jin-Kyu;
Shimizu, Makoto;
Huang, Zhi-Li

Publication type:

Article

NeuM: A Neuron‐Selective Probe Incorporates into Live Neuronal Membranes via Enhanced Clathrin‐Mediated Endocytosis in Primary Neurons.

Published in:

Angewandte Chemie International Edition, 2024, v. 63, n. 3, p. 1, doi. 10.1002/anie.202312942

By:

Sung, Yoonsik;
Gotina, Lizaveta;
Kim, Kyu Hyeon;
Lee, Jung Yeol;
Shin, Seulgi;
Aziz, Hira;
Kang, Dong Min;
Liu, Xiao;
Hong, Na‐Kyeong;
Lee, Hong‐Guen;
Lee, Jun‐Seok;
Ku, Hyeyeong;
Jeong, Cherlhyun;
Pae, Ae Nim;
Lim, Sungsu;
Chang, Young‐Tae;
Kim, Yun Kyung

Publication type:

Article

Synthesis and Evaluation of 2β-0xyimino and Alkenylpenicillanic Acid Sulfone Derivatives as β-Lactamase Inhibitors.

Published in:

Archiv der Pharmazie, 1999, v. 332, n. 1, p. 7, doi. 10.1002/(SICI)1521-4184(19991)332:1<7::AID-ARDP7>3.0.CO;2-M

By:

Cho, Young Seo;
Ha, Young Jin;
Kwon, Jin Sun;
Pae, Ae Nim;
Il Choi, Kyung;
Koh, Hun Yeong;
Chang, Moon Ho;
Yoon, Cheol-Min;
Lee, Gwan Sun

Publication type:

Article

Pharmacophore-Based Virtual Screening of Novel Competitive Inhibitors of the Neurodegenerative Disease Target Kynurenine-3-Monooxygenase.

Published in:

Molecules, 2021, v. 26, n. 11, p. 3314, doi. 10.3390/molecules26113314

By:

Gotina, Lizaveta;
Seo, Seon Hee;
Kim, Chae Won;
Lim, Sang Min;
Pae, Ae Nim

Publication type:

Article

Investigation of Molecular Details of Keap1-Nrf2 Inhibitors Using Molecular Dynamics and Umbrella Sampling Techniques.

Published in:

Molecules, 2019, v. 24, n. 22, p. 4085, doi. 10.3390/molecules24224085

By:

Londhe, Ashwini Machhindra;
Gadhe, Changdev Gorakshnath;
Lim, Sang Min;
Pae, Ae Nim;
Gemma, Sandra

Publication type:

Article

Synthesis and Biological Evaluation of Disubstituted Pyrimidines as Selective 5-HT2C Agonists.

Published in:

Molecules, 2019, v. 24, n. 18, p. 3234, doi. 10.3390/molecules24183234

By:

Kim, Juhyeon;
Kim, Yoon Jung;
Londhe, Ashwini M.;
Pae, Ae Nim;
Choo, Hyunah;
Kim, Hak Joong;
Min, Sun-Joon

Publication type:

Article

Identification of Optically Active Pyrimidine Derivatives as Selective 5-HT2C Modulators.

Published in:

Molecules, 2017, v. 22, n. 9, p. 1416, doi. 10.3390/molecules22091416

By:

Juhyeon Kim;
Hanbyeol Jo;
Hyunseung Lee;
Hyunah Choo;
Hak Joong Kim;
Ae Nim Pae;
Yong Seo Cho;
Sun-Joon Min

Publication type:

Article

Antioxidant and Anti-Inflammatory Activities of a Natural Compound, Shizukahenriol, through Nrf2 Activation.

Published in:

Molecules, 2015, v. 20, n. 9, p. 15989, doi. 10.3390/molecules200915989

By:

Jong-Hyun Park;
Ji Won Choi;
Eun Ji Ju;
Ae Nim Pae;
Ki Duk Park

Publication type:

Article

Remodeling of heterochromatin structure slows neuropathological progression and prolongs survival in an animal model of Huntington's disease.

Published in:

Acta Neuropathologica, 2017, v. 134, n. 5, p. 729, doi. 10.1007/s00401-017-1732-8

By:

Lee, Junghee;
Hwang, Yu;
Kim, Yunha;
Lee, Min;
Hyeon, Seung;
Lee, Soojin;
Kim, Dong;
Jang, Sung;
Im, Hyoenjoo;
Min, Sun-Joon;
Choo, Hyunah;
Pae, Ae;
Cho, Kyung;
Kowall, Neil;
Ryu, Hoon

Publication type:

Article

Molecular Characterization of Hepatitis C Virus for Developed Antiviral Agents Resistance Mutations and New Insights into in-silico Prediction Studies.

Published in:

Infection & Drug Resistance, 2020, v. 13, p. 4235, doi. 10.2147/IDR.S267809

By:

El-Sokkary, Mohamed M Adel;
Gotina, Lizaveta;
Al-Sanea, Mohammad M;
Pae, Ae Nim;
Elbargisy, Rehab Mohammed

Publication type:

Article

Structural hybridization for inhibitors of the interaction between NRF2 and Keap1.

Published in:

Bulletin of the Korean Chemical Society, 2022, v. 43, n. 9, p. 1088, doi. 10.1002/bkcs.12591

By:

Lee, Dong Heun;
Seo, Seon Hee;
Gotina, Lizaveta;
Pae, Ae Nim;
Lim, Sang Min

Publication type:

Article

A Novel Phenylsulfonamide Ameliorates the Cognitive Impairment in Mice Induced by Scopolamine.

Published in:

Bulletin of the Korean Chemical Society, 2018, v. 39, n. 7, p. 891, doi. 10.1002/bkcs.11486

By:

Kim, Sun Young;
Jung, Da Woon;
Yoon, Hong Bin;
Lee, Hwi‐Ho;
Lee, Jeong‐Hun;
Shin, Ji Sun;
Lim, Dami;
Kim, Hyoung Ja;
Pae, Ae Nim;
Park, Jeong Ho;
Ryu, Jong Hoon;
Lee, Kyung‐Tae;
Lee, Jae Yeol

Publication type:

Article

Synthesis and Biological Evaluation of Substituted Pyrazole Constrained Piperazine Derivative Library for Dopamine Receptor Antagonist.

Published in:

Bulletin of the Korean Chemical Society, 2016, v. 37, n. 12, p. 2076, doi. 10.1002/bkcs.11012

By:

Landge, Kamalkishor P.;
Song, Hyun Ju;
Lee, Jung Gook;
Chae, Sang Eun;
Pae, Ae Nim;
Park, Woo Kyu;
Sampath, Vasu;
Lee, Hee Yoon;
Koh, Hun Yeong

Publication type:

Article

Isoxazoline, Isoxazole, and Oxadiazole Derivatives as M1 Muscarinic Acetylcholine Receptor Agonists.

Published in:

Bulletin of the Korean Chemical Society, 2016, v. 37, n. 7, p. 1020, doi. 10.1002/bkcs.10811

By:

Muthusamy, Selvaraj;
Lee, Soo Min;
Huang, Minghua;
Cho, Nam-Chul;
Nam, Ghilsoo;
Pae, Ae Nim;
Rhim, Hyewhon;
Keum, Gyochang;
Choi, Kyung Il

Publication type:

Article

Synthesis and Biological Evaluation of 2-Phenylimino-5((5-phenylfuran-2-yl)methylene)thiazolidin-4-ones as IKK2 Inhibitors.

Published in:

Bulletin of the Korean Chemical Society, 2015, v. 36, n. 11, p. 2621, doi. 10.1002/bkcs.10528

By:

Kim, Hee Sook;
Shin, Min Jae;
Lee, Byungho;
Oh, Kwang-Seok;
Choo, Hyunah;
Pae, Ae Nim;
Roh, Eun Joo;
Nam, Ghilsoo

Publication type:

Article

Synthesis and In vivo Evaluation of 5-Methoxy-2-(phenylethynyl)quinoline (MPEQ) and [11C]MPEQ Targeting Metabotropic Glutamate Receptor 5 (mGluR5).

Published in:

Bulletin of the Korean Chemical Society, 2014, v. 35, n. 8, p. 2304, doi. 10.5012/bkcs.2014.35.8.2304

By:

Ji Young Kim;
Myung-Hee Son;
Kihang Choi;
Du-Jong Baek;
Min Kyung Ko;
Eun Jeong Lim;
Ae Nim Pae;
Gyochang Keum;
Jae Kyun Lee;
Yong Seo Cho;
Hyunah Choo;
Youn Woo Lee;
Byung Seok Moon;
Byung Cheol Lee;
Ho-Young Lee;
Sun-Joon Min

Publication type:

Article

Discovery of non-peptidic small molecule inhibitors of cyclophilin D as neuroprotective agents in Aβ-induced mitochondrial dysfunction.

Published in:

Journal of Computer-Aided Molecular Design, 2017, v. 31, n. 10, p. 929, doi. 10.1007/s10822-017-0067-9

By:

Park, Insun;
Londhe, Ashwini;
Lim, Ji;
Park, Beoung-Geon;
Jung, Seo;
Lee, Jae;
Lim, Sang;
No, Kyoung;
Lee, Jiyoun;
Pae, Ae

Publication type:

Article

In silico probing and biological evaluation of SETDB1/ESET-targeted novel compounds that reduce tri-methylated histone H3K9 (H3K9me3) level.

Published in:

Journal of Computer-Aided Molecular Design, 2017, v. 31, n. 10, p. 877, doi. 10.1007/s10822-017-0052-3

By:

Park, Insun;
Hwang, Yu;
Kim, TaeHun;
Viswanath, Ambily;
Londhe, Ashwini;
Jung, Seo;
Sim, Kyoung;
Min, Sun-Joon;
Lee, Ji;
Seong, Jihye;
Kim, Yun;
No, Kyoung;
Ryu, Hoon;
Pae, Ae

Publication type:

Article

Pharmacophore-based virtual screening, biological evaluation and binding mode analysis of a novel protease-activated receptor 2 antagonist.

Published in:

Journal of Computer-Aided Molecular Design, 2016, v. 30, n. 8, p. 625, doi. 10.1007/s10822-016-9937-9

By:

Cho, Nam-Chul;
Seo, Seoung-Hwan;
Kim, Dohee;
Shin, Ji-Sun;
Ju, Jeongmin;
Seong, Jihye;
Seo, Seon;
Lee, Iiyoun;
Lee, Kyung-Tae;
Kim, Yun;
No, Kyoung;
Pae, Ae

Publication type:

Article

GRP78‐targeted in‐silico virtual screening of novel anticancer agents.

Published in:

Chemical Biology & Drug Design, 2018, v. 92, n. 2, p. 1555, doi. 10.1111/cbdd.13322

By:

Viswanath, Ambily Nath Indu;
Lim, Ji Woong;
Seo, Seon Hee;
Lee, Jae Yeol;
Lim, Sang Min;
Pae, Ae Nim

Publication type:

Article

In silico-designed novel non-peptidic ABAD LD hot spot mimetics reverse Aβ-induced mitochondrial impairments in vitro.

Published in:

2017

By:

Viswanath, Ambily Nath Indu;
Kim, TaeHun;
Jung, Seo Yun;
Lim, Sang Min;
Pae, Ae Nim

Publication type:

Editorial

Design and synthesis of new 2-anilinoquinolines bearing N-methylpicolinamide moiety as potential antiproliferative agents.

Published in:

Chemical Biology & Drug Design, 2017, v. 89, n. 1, p. 98, doi. 10.1111/cbdd.12836

By:

El ‐ Damasy, Ashraf Kareem;
Seo, Seon Hee;
Cho, Nam ‐ Chul;
Pae, Ae Nim;
Kim, Eunice Eunkyeong;
Keum, Gyochang

Publication type:

Article

Identification of the first in silico-designed TREK1 antagonists that block channel currents dose dependently.

Published in:

Chemical Biology & Drug Design, 2016, v. 88, n. 6, p. 807, doi. 10.1111/cbdd.12810

By:

Viswanath, Ambily Nath Indu;
Jung, Seo Yun;
Hwang, Eun Mi;
Park, Ki Duk;
Lim, Sang Min;
Min, Sun ‐ Joon;
Cho, Yong Seo;
Pae, Ae Nim

Publication type:

Article

Novel Scaffold Identification of mGlu1 Receptor Negative Allosteric Modulators Using a Hierarchical Virtual Screening Approach.

Published in:

Chemical Biology & Drug Design, 2016, v. 87, n. 2, p. 239, doi. 10.1111/cbdd.12654

By:

Jang, Jae Wan;
Cho, Nam ‐ Chul;
Min, Sun ‐ Joon;
Cho, Yong Seo;
Park, Ki Duk;
Seo, Seon Hee;
No, Kyoung Tai;
Pae, Ae Nim

Publication type:

Article

Tubulin Inhibitor Identification by Bioactive Conformation Alignment Pharmacophore-Guided Virtual Screening.

Published in:

Chemical Biology & Drug Design, 2015, v. 86, n. 5, p. 998, doi. 10.1111/cbdd.12568

By:

Nagarajan, Shanthi;
Choi, Min Jeong;
Cho, Yong Seo;
Min, Sun ‐ Joon;
Keum, Gyochang;
Kim, Soo Jin;
Lee, Chang Sik;
Pae, Ae Nim

Publication type:

Article

Synthesis and In Vitro Antibacterial Activity of Novel 3-Azabicyclo[3.3.0]octanyl Oxazolidinones.

Published in:

Chemical Biology & Drug Design, 2012, v. 80, n. 3, p. 388, doi. 10.1111/j.1747-0285.2012.01404.x

By:

Bhattarai, Deepak;
Lee, Sun H.;
Seo, Seon H.;
Nam, Ghilsoo;
Kang, Soon B.;
Pae, Ae N.;
Kim, Eunice E.;
Oh, Taegwon;
Cho, Sang-Nae;
Keum, Gyochang

Publication type:

Article

Highly Potent, Selective, and Competitive Indole-Based MAO-B Inhibitors Protect PC12 Cells against 6-Hydroxydopamine- and Rotenone-Induced Oxidative Stress.

Published in:

Antioxidants, 2021, v. 10, n. 10, p. 1641, doi. 10.3390/antiox10101641

By:

Elsherbeny, Mohamed H.;
Kim, Jushin;
Gouda, Noha A.;
Gotina, Lizaveta;
Cho, Jungsook;
Pae, Ae Nim;
Lee, Kyeong;
Park, Ki Duk;
Elkamhawy, Ahmed;
Roh, Eun Joo

Publication type:

Article

Discovery of a Nanomolar Multikinase Inhibitor (KST016366): A New Benzothiazole Derivative with Remarkable Broad-Spectrum Antiproliferative Activity.

Published in:

ChemMedChem, 2016, v. 11, n. 15, p. 1587, doi. 10.1002/cmdc.201600224

By:

El‐Damasy, Ashraf Kareem;
Cho, Nam‐Chul;
Nam, Ghilsoo;
Pae, Ae Nim;
Keum, Gyochang

Publication type:

Article

Inside Cover: Screening, Synthesis, and In Vitro Evaluation of Vinyl Sulfones as Inhibitors of Complement-Dependent Cytotoxicity in Neuromyelitis Optica (ChemMedChem 4/2016).

Published in:

ChemMedChem, 2016, v. 11, n. 4, p. 352, doi. 10.1002/cmdc.201600046

By:

Ju, Eun Ji;
Yeon, Seul Ki;
Park, Jong‐Hyun;
Cheon, So Young;
Choi, Ji Won;
Ha, Taehwan;
Jang, Bo Ko;
Kim, Siwon;
Kang, Yong Gu;
Hwang, Hayoung;
Cho, Sung Jin;
Cheong, Eunji;
Bahn, Yong Sun;
Pae, Ae Nim;
Kim, Sung Min;
Park, Ki Duk

Publication type:

Article

Screening, Synthesis, and In Vitro Evaluation of Vinyl Sulfones as Inhibitors of Complement-Dependent Cytotoxicity in Neuromyelitis Optica.

Published in:

ChemMedChem, 2016, v. 11, n. 4, p. 377, doi. 10.1002/cmdc.201500546

By:

Ju, Eun Ji;
Yeon, Seul Ki;
Park, Jong‐Hyun;
Cheon, So Young;
Choi, Ji Won;
Ha, Taehwan;
Jang, Bo Ko;
Kim, Siwon;
Kang, Yong Gu;
Hwang, Hayoung;
Cho, Sung Jin;
Cheong, Eunji;
Bahn, Yong Sun;
Pae, Ae Nim;
Kim, Sung Min;
Park, Ki Duk

Publication type:

Article

Aβ modulates actin cytoskeleton via SHIP2-mediated phosphoinositide metabolism.

Published in:

Scientific Reports, 2019, v. 9, n. 1, p. N.PAG, doi. 10.1038/s41598-019-51914-2

By:

Lee, Hae Nim;
Sim, Kyoung Mi;
Kim, Hyunbin;
Ju, Jeongmin;
Pae, Ae Nim;
Park, Jae-Bong;
Ryu, Hoon;
Seong, Jihye

Publication type:

Article

Intermolecular Double Prins-Type Cyclization: A Facile and Efficient Synthesis of 1,6-Dioxecanes.

Published in:

Angewandte Chemie International Edition, 2009, v. 48, n. 34, p. 6190, doi. 10.1002/anie.200990178

By:

Ullapu, Punna Reddy;
Min, Sun-Joon;
Chavre, Satish N.;
Choo, Hyunah;
Lee, Jae Kyun;
Pae, Ae Nim;
Kim, Youseung;
Chang, Moon Ho;
Cho, Yong Seo

Publication type:

Article

Intermolecular Double Prins-Type Cyclization: A Facile and Efficient Synthesis of 1,6-Dioxecanes.

Published in:

Angewandte Chemie International Edition, 2009, v. 48, n. 12, p. 2196, doi. 10.1002/anie.200804576

By:

Ullapu, Punna Reddy;
Min, Sun-Joon;
Chavre, Satish N.;
Choo, Hyunah;
Lee, Jae Kyun;
Pae, Ae Nim;
Kim, Youseung;
Chang, Moon Ho;
Cho, Yong Seo

Publication type:

Article

Epigenetic regulation of cholinergic receptor M1 (CHRM1) by histone H3K9me3 impairs Ca signaling in Huntington's disease.

Published in:

Acta Neuropathologica, 2013, v. 125, n. 5, p. 727, doi. 10.1007/s00401-013-1103-z

By:

Lee, Junghee;
Hwang, Yu;
Shin, Jong-Yeon;
Lee, Won-Chul;
Wie, Jinhong;
Kim, Ki;
Lee, Min;
Hwang, Daehee;
Ratan, Rajiv;
Pae, Ae;
Kowall, Neil;
So, Insuk;
Kim, Jong-Il;
Ryu, Hoon

Publication type:

Article

Neuroprotective Effects of Ethanol Extract Polyscias guilfoylei (EEPG) Against Glutamate Induced Neurotoxicity in HT22 Cells.

Published in:

International Journal of Molecular Sciences, 2024, v. 25, n. 22, p. 12153, doi. 10.3390/ijms252212153

By:

Nguyen, Qui Ngoc Sang;
Yoo, Ki-Yeon;
Pham, Thi Thu Trang;
Selvaraj, Baskar;
Vu, Huong Thuy;
Le, Tam Thi;
Lee, Heesu;
Tran, Quang Luc;
Thuong, Phuong Thien;
Pae, Ae Nim;
Jung, Sang Hoon;
Lee, Jae Wook

Publication type:

Article

Neuroprotective Effects of Ethanol Extract of Polyscias fruticosa (EEPF) against Glutamate-Mediated Neuronal Toxicity in HT22 Cells.

Published in:

International Journal of Molecular Sciences, 2023, v. 24, n. 4, p. 3969, doi. 10.3390/ijms24043969

By:

Selvaraj, Baskar;
Le, Tam Thi;
Kim, Dae Won;
Jung, Bo Hyun;
Yoo, Ki-Yeon;
Ahn, Hong Ryul;
Thuong, Phuong Thien;
Tran, Thi Thu Thuy;
Pae, Ae Nim;
Jung, Sang Hoon;
Lee, Jae Wook

Publication type:

Article

IKKβ inhibitor identification: a multi-filter driven novel scaffold.

Published in:

BMC Bioinformatics, 2010, v. 11, p. 1

By:

Nagarajan, Shanthi;
Choo, Hyunah;
Cho, Yong Seo;
Shin, Kye Jung;
Oh, Kwang-Seok;
Lee, Byung Ho;
Pae, Ae Nim

Publication type:

Article

NeuM: A Neuron‐Selective Probe Incorporates into Live Neuronal Membranes via Enhanced Clathrin‐Mediated Endocytosis in Primary Neurons.

Published in:

Angewandte Chemie, 2024, v. 136, n. 3, p. 1, doi. 10.1002/ange.202312942

By:

Sung, Yoonsik;
Gotina, Lizaveta;
Kim, Kyu Hyeon;
Lee, Jung Yeol;
Shin, Seulgi;
Aziz, Hira;
Kang, Dong Min;
Liu, Xiao;
Hong, Na‐Kyeong;
Lee, Hong‐Guen;
Lee, Jun‐Seok;
Ku, Hyeyeong;
Jeong, Cherlhyun;
Pae, Ae Nim;
Lim, Sungsu;
Chang, Young‐Tae;
Kim, Yun Kyung

Publication type:

Article

Platycodin D, a natural component of Platycodon grandiflorum, prevents both lysosome- and TMPRSS2-driven SARS-CoV-2 infection by hindering membrane fusion.

Published in:

Experimental & Molecular Medicine EMM, 2021, v. 53, n. 5, p. 956, doi. 10.1038/s12276-021-00624-9

By:

Kim, Tai Young;
Jeon, Sangeun;
Jang, Youngho;
Gotina, Lizaveta;
Won, Joungha;
Ju, Yeon Ha;
Kim, Sunpil;
Jang, Minwoo Wendy;
Won, Woojin;
Park, Mingu Gordon;
Pae, Ae Nim;
Han, Sunkyu;
Kim, Seungtaek;
Lee, C. Justin

Publication type:

Article

CRISPR-mediated gene correction links the ATP7A M1311V mutations with amyotrophic lateral sclerosis pathogenesis in one individual.

Published in:

Communications Biology, 2020, v. 3, n. 1, p. 1, doi. 10.1038/s42003-020-0755-1

By:

Yun, Yeomin;
Hong, Sung-Ah;
Kim, Ka-Kyung;
Baek, Daye;
Lee, Dongsu;
Londhe, Ashwini M.;
Lee, Minhyung;
Yu, Jihyeon;
McEachin, Zachary T.;
Bassell, Gary J.;
Bowser, Robert;
Hales, Chadwick M.;
Cho, Sung-Rae;
Kim, Janghwan;
Pae, Ae Nim;
Cheong, Eunji;
Kim, Sangwoo;
Boulis, Nicholas M.;
Bae, Sangsu;
Ha, Yoon

Publication type:

Article

Development of Oxadiazole-Based ODZ10117 as a Small-Molecule Inhibitor of STAT3 for Targeted Cancer Therapy.

Published in:

Journal of Clinical Medicine, 2019, v. 8, n. 11, p. 1847, doi. 10.3390/jcm8111847

By:

Kim, Byung-Hak;
Lee, Haeri;
Song, Yeonghun;
Park, Joon-Suk;
Gadhe, Changdev G.;
Choi, Jiwon;
Lee, Chung-Gi;
Pae, Ae Nim;
Kim, Sanghee;
Ye, Sang-Kyu

Publication type:

Article

Development of an Aryloxazole Derivative as a Brain-Permeable Anti-Glioblastoma Agent.

Published in:

Pharmaceutics, 2019, v. 11, n. 10, p. 497, doi. 10.3390/pharmaceutics11100497

By:

Shin, Seulgi;
Lim, Sungsu;
Song, Ji Yeon;
Kim, Dohee;
Choi, Min Jeong;
Gadhe, Changdev G.;
Park, A Young;
Pae, Ae Nim;
Kim, Yun Kyung

Publication type:

Article

DA‐7503, a novel tau aggregation inhibitor, ameliorates tau pathology and reduces CSF tau in transgenic mouse models of Alzheimer's disease and primary tauopathies.

Published in:

Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2024, v. 20, n. S6, p. 1, doi. 10.1002/alz.084642

By:

Lee, Min Jung;
Choi, Song‐hyen;
Moon, Jun‐Hwan;
Lee, Hyangsoo;
Kim, Eunjin;
Lee, Dae Young;
Lim, Sungsu;
Kim, Yun Kyung;
Pae, Ae Nim

Publication type:

Article

Discovery of DA‐7503 as a Novel Tau‐targeted Therapeutic Candidate for the Treatment of Alzheimer's Disease.

Published in:

Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2022, v. 18, n. 10, p. 1, doi. 10.1002/alz.061119

By:

Pae, Ae Nim;
Lim, Sungsu;
Lim, Sang Min;
Lee, Hyangsoo;
Lee, Min Jung;
Kim, Yun Kyung

Publication type:

Article

Visualization of tau oligomers in TauP301L‐BiFC transgenic mice exhibits the progression of tauopathy.

Published in:

Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2022, v. 18, n. 3, p. 1, doi. 10.1002/alz.062847

By:

Lim, Sungsu;
Pae, Ae Nim;
Kim, Yun Kyung

Publication type:

Article

DISCOVERY OF NOVEL TSPO LIGANDS AS MODULATORS OF MITOCHONDRIAL FUNCTION: A POTENTIAL TREATMENT FOR ALZHEIMER’S DISEASE.

Published in:

Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2016, v. 12, p. P431, doi. 10.1016/j.jalz.2016.06.825

By:

Kim, TaeHun;
Park, Beung Gun;
Lee, Jiyoun;
Pae, Ae Nim

Publication type:

Article

Structural determinants for activation of the Tau kinase CDK5 by the serotonin receptor 5-HT7R.

Published in:

Cell Communication & Signaling, 2024, v. 22, n. 1, p. 1, doi. 10.1186/s12964-024-01612-y

By:

Ackmann, Jana;
Brüge, Alina;
Gotina, Lizaveta;
Lim, Sungsu;
Jahreis, Kathrin;
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Cho, Yong Seo;
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