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Synthesis of Glycosyl Phosphonates by Michael-Type Addition to 2-Nitroglycals.
- Published in:
- European Journal of Organic Chemistry, 2004, v. 2004, n. 19, p. 3959, doi. 10.1002/ejoc.200400266
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- Article
Antibacterial Aminoglycosides with a Modified Mode of Binding to the Ribosomal-RNA Decoding Site.
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- Angewandte Chemie International Edition, 2007, v. 46, n. 17, p. 2971, doi. 10.1002/anie.200790074
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- Article
Biodegradable Lipids Enabling Rapidly Eliminated Lipid Nanoparticles for Systemic Delivery of RNAi Therapeutics.
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- Molecular Therapy, 2013, v. 21, n. 8, p. 1570, doi. 10.1038/mt.2013.124
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- Article
Antibacterial Aminoglycosides with a Modified Mode of Binding to the Ribosomal-RNA Decoding SiteWe thank the NSERC and the Institut Universitaire de France for financial assistance provided to S.H. and E.W., respectively. Thanks are due to Lisa M. Risen for transcription/translation and MIC assays, and Dr. Kristen A. Sannes-Lowery for the KD determinations. We acknowledge the European Synchrotron Radiation Facility for provision of synchrotron radiation facilities, and we thank Stéphanie Monaco and Joanne McCarthy for assistance with the use of beamlines ID14-2 and ID14-4.
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- Angewandte Chemie, 2004, v. 116, n. 48, p. 6903
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- Article
O4‐05‐02: THE INVESTIGATIONAL STEREOPURE ANTISENSE OLIGONUCLEOTIDE WVE‐3972‐01 PREFERENTIALLY REDUCES G<sub>4</sub>C<sub>2</sub> REPEAT‐CONTAINING C9ORF72 TRANSCRIPTS: A POTENTIAL THERAPEUTIC APPROACH FOR THE TREATMENT OF FRONTOTEMPORAL DEMENTIA
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- Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2018, v. 14, p. P1411, doi. 10.1016/j.jalz.2018.06.2934
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- Article
Variant-selective stereopure oligonucleotides protect against pathologies associated with C9orf72-repeat expansion in preclinical models.
- Published in:
- Nature Communications, 2021, v. 12, n. 1, p. 1, doi. 10.1038/s41467-021-21112-8
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- Article
Crystal Structure of the Bacterial Ribosomal Decoding Site Complexed with a Synthetic Doubly Functionalized Paromomycin Derivative: a New Specific Binding Mode to an A-Minor Motif Enhances in vitro Antibacterial Activity.
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- ChemMedChem, 2007, v. 2, n. 11, p. 1631, doi. 10.1002/cmdc.200700113
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- Article
Control of backbone chemistry and chirality boost oligonucleotide splice switching activity.
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- Nucleic Acids Research, 2022, v. 50, n. 10, p. 5443, doi. 10.1093/nar/gkac018
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- Publication type:
- Article
Antibacterial Aminoglycosides with a Modified Mode of Binding to the Ribosomal-RNA Decoding SiteWe thank the NSERC and the Institut Universitaire de France for financial assistance provided to S.H. and E.W., respectively. Thanks are due to Lisa M. Risen for transcription/translation and MIC assays, and Dr. Kristen A. Sannes-Lowery for the KD determinations. We acknowledge the European Synchrotron Radiation Facility for provision of synchrotron radiation facilities, and we thank Stéphanie Monaco and Joanne McCarthy for assistance with the use of beamlines ID14-2 and ID14-4.
- Published in:
- Angewandte Chemie International Edition, 2004, v. 43, n. 48, p. 6735
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- Publication type:
- Article
WVE‐005, a stereopure antisense oligonucleotide for MAPT silencing in tauopathies.
- Published in:
- Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2022, v. 18, n. 10, p. 1, doi. 10.1002/alz.063730
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- Article