Works matching AU Pace, Betty S.

Results: 33

Simvastatin-Mediated Nrf2 Activation Induces Fetal Hemoglobin and Antioxidant Enzyme Expression to Ameliorate the Phenotype of Sickle Cell Disease.

Published in:

Antioxidants, 2024, v. 13, n. 3, p. 337, doi. 10.3390/antiox13030337

By:

Xi, Caixia;
Palani, Chithra;
Takezaki, Mayuko;
Shi, Huidong;
Horuzsko, Anatolij;
Pace, Betty S.;
Zhu, Xingguo

Publication type:

Article

FK228 Analogues Induce Fetal Hemoglobin in Human Erythroid Progenitors.

Published in:

Anemia (20901267), 2012, p. 1, doi. 10.1155/2012/428137

By:

Makala, Levi;
Di Maro, Salvatore;
Tzu-Fang Lou;
Sivanand, Sharanya;
Jung-Mo Ahn;
Pace, Betty S.

Publication type:

Article

Sickle Cell Disease: Genetics, Cellular and Molecular Mechanisms, and Therapies.

Published in:

Anemia (20901267), 2012, p. 1, doi. 10.1155/2012/143594

By:

Pace, Betty S.;
Ofori-Acquah, Solomon F.;
Peterson, Kenneth R.

Publication type:

Article

Salubrinal induces fetal hemoglobin expression via the stress-signaling pathway in human sickle erythroid progenitors and sickle cell disease mice.

Published in:

PLoS ONE, 2022, v. 17, n. 5, p. 1, doi. 10.1371/journal.pone.0261799

By:

Lopez, Nicole H.;
Li, Biaoru;
Palani, Chithra;
Siddaramappa, Umapathy;
Takezaki, Mayuko;
Xu, Hongyan;
Zhi, Wenbo;
Pace, Betty S.

Publication type:

Article

Endothelial ENaC-α Restrains Oxidative Stress in Lung Capillaries in Murine Pneumococcal Pneumonia–associated Acute Lung Injury.

Published in:

American Journal of Respiratory Cell & Molecular Biology, 2025, v. 72, n. 4, p. 429, doi. 10.1165/rcmb.2023-0440OC

By:

Romero, Maritza J.;
Yue, Qian;
Ahn, Won Mo;
Hamacher, Jürg;
Zaidi, Yusra;
Haigh, Stephen;
Sridhar, Supriya;
Gonzales, Joyce;
Hudel, Martina;
Huo, Yuqing;
Verin, Alexander D.;
Pace, Betty S.;
Stansfield, Brian K.;
Maishan, Mazharul;
Neptune, Enid R.;
Enkhbaatar, Perenlei;
Su, Yunchao;
Chakraborty, Trinad;
Gonsalvez, Graydon;
Hummler, Edith

Publication type:

Article

Enhancing diversity in the hematology biomedical research workforce: A mentoring program to improve the odds of career success for early stage investigators.

Published in:

American Journal of Hematology, 2017, v. 92, n. 12, p. 1275, doi. 10.1002/ajh.24899

By:

Pace, Betty S.;
Makala, Levi H.;
Sarkar, Rita;
Liu, Li;
Takezaki, Mayuko;
Mohandas, Narla;
Dixon, Glorias;
Werner, Ellen M.;
Jeffe, Donna B.;
Rice, Treva K.;
Maihle, Nita J.;
González, Juan

Publication type:

Article

Biomechanical and biochemical regulation of cathepsin K expression in endothelial cells converge at AP-1 and NF-κB.

Published in:

Biological Chemistry, 2016, v. 397, n. 5, p. 459, doi. 10.1515/hsz-2015-0244

By:

Keegan, Philip M.;
Anbazhakan, Suhaas;
Kang, Baolin;
Pace, Betty S.;
Platt, Manu O.

Publication type:

Article

Understanding mechanisms of γ‐globin gene regulation to develop strategies for pharmacological fetal hemoglobin induction.

Published in:

Developmental Dynamics, 2006, v. 235, n. 7, p. 1727

By:

Betty S. Pace;
Sima Zein

Publication type:

Article

Krüppel-like Factor 4 activates HBG gene expression in primary erythroid cells.

Published in:

British Journal of Haematology, 2011, v. 154, n. 2, p. 248, doi. 10.1111/j.1365-2141.2011.08710.x

By:

Kalra, Inderdeep S.;
Alam, Md M.;
Choudhary, Pankaj K.;
Pace, Betty S.

Publication type:

Article

NRF2 mediates γ-globin gene regulation through epigenetic modifications in a β-YAC transgenic mouse model.

Published in:

Experimental Biology & Medicine, 2020, v. 245, n. 15, p. 1308, doi. 10.1177/1535370220945305

By:

Zhu, Xingguo;
Xi, Caixia;
Ward, Alexander;
Takezaki, Mayuko;
Shi, Huidong;
Peterson, Kenneth R;
Pace, Betty S

Publication type:

Article

Feature article: δ-Aminolevulinate induces fetal hemoglobin expression by enhancing cellular heme biosynthesis.

Published in:

Experimental Biology & Medicine, 2019, v. 244, n. 14, p. 1220, doi. 10.1177/1535370219872995

By:

Liu, Li;
Zhu, Xingguo;
Yu, Alexander;
Ward, Christina M;
Pace, Betty S

Publication type:

Article

Mechanisms of NRF2 activation to mediate fetal hemoglobin induction and protection against oxidative stress in sickle cell disease.

Published in:

Experimental Biology & Medicine, 2019, v. 244, n. 2, p. 171, doi. 10.1177/1535370219825859

By:

Zhu, Xingguo;
Oseghale, Aluya R.;
Nicole, Lopez H.;
Li, Biaoru;
Pace, Betty S.

Publication type:

Article

Original Research: A case-control genome-wide association study identifies genetic modifiers of fetal hemoglobin in sickle cell disease.

Published in:

Experimental Biology & Medicine, 2016, v. 241, n. 7, p. 706, doi. 10.1177/1535370216642047

By:

Liu, Li;
Pertsemlidis, Alexander;
Ding, Liang-Hao;
Story, Michael D.;
Steinberg, Martin H.;
Sebastiani, Paola;
Hoppe, Carolyn;
Ballas, Samir K.;
Pace, Betty S.

Publication type:

Article

Sickle cell disease severity: an introduction.

Published in:

Experimental Biology & Medicine, 2016, v. 241, n. 7, p. 677, doi. 10.1177/1535370216641880

By:

Pace, Betty S.;
Goodman, Steven R.

Publication type:

Article

Minireview: Multiomic candidate biomarkers for clinical manifestations of sickle cell severity: Early steps to precision medicine.

Published in:

Experimental Biology & Medicine, 2016, v. 241, n. 7, p. 772, doi. 10.1177/1535370216640150

By:

Goodman, Steven R.;
Pace, Betty S.;
Hansen, Kirk C.;
D’alessandro, Angelo;
Xia, Yang;
Daescu, Ovidiu;
Glatt, Stephen J.

Publication type:

Article

Original Research: Stable expression of miR-34a mediates fetal hemoglobin induction in K562 cells.

Published in:

Experimental Biology & Medicine, 2016, v. 241, n. 7, p. 719, doi. 10.1177/1535370216636725

By:

Ward, Christina M.;
Li, Biaoru;
Pace, Betty S.

Publication type:

Article

Cell signaling pathways involved in drug-mediated fetal hemoglobin induction: Strategies to treat sickle cell disease.

Published in:

Experimental Biology & Medicine, 2015, v. 240, n. 8, p. 1050, doi. 10.1177/1535370215596859

By:

Pace, Betty S.;
Liu, Li;
Li, Biaoru;
Makala, Levi H.

Publication type:

Article

Stroke in a child with hemoglobin SC disease: a case report describing use of hydroxyurea after transfusion therapy.

Published in:

2017

By:

Fridly, Diana;
Wilder, Caroline;
Leila Jerome Clay, E.;
Gilbert, Bruce;
Pace, Betty S.

Publication type:

Case Study

The histone deacetylase inhibitor CT-101 flips the switch to fetal hemoglobin expression in sickle cell disease mice.

Published in:

PLoS ONE, 2025, v. 20, n. 5, p. 1, doi. 10.1371/journal.pone.0323550

By:

Takezaki, Mayuko;
Li, Biaoru;
Xu, Hongyan;
Patel, Nikhil;
Lucas, Rudolf;
Cerbone, Ryan E.;
Koti, Sivanagireddy;
Hendrick, Clifford L.;
Junker, Louis H.;
Pace, Betty S.

Publication type:

Article

Ethanol Exposure Induces Neonatal Neurodegeneration by Enhancing CB1R Exon1 Histone H4K8 Acetylation and Up-regulating CB1R Function causing Neurobehavioral Abnormalities in Adult Mice.

Published in:

International Journal of Neuropsychopharmacology, 2015, v. 18, n. 5, p. 1, doi. 10.1093/ijnp/pyu028

By:

Subbanna, Shivakumar;
Nagre, Nagaraja N.;
Umapathy, Nagavedi S.;
Pace, Betty S.;
Basavarajappa, Balapal S.

Publication type:

Article

Targeting Genetic Modifiers of HBG Gene Expression in Sickle Cell Disease: The miRNA Option.

Published in:

2022

By:

Starlard-Davenport, Athena;
Gu, Qingqing;
Pace, Betty S.

Publication type:

Literature Review

Author Correction: Machine learning-based approaches for identifying human blood cells harboring CRISPR-mediated fetal chromatin domain ablations.

Published in:

2024

By:

Li, Yi;
Zaheri, Shadi;
Nguyen, Khai;
Liu, Li;
Hassanipour, Fatemeh;
Pace, Betty S.;
Bleris, Leonidas

Publication type:

Correction Notice

Exploring epigenetic and microRNA approaches for γ-globin gene regulation.

Published in:

Experimental Biology & Medicine, 2021, v. 246, n. 22, p. 2347, doi. 10.1177/15353702211028195

By:

Starlard-Davenport, Athena;
Fitzgerald, Ashley;
Pace, Betty S

Publication type:

Article

Sickle cell disease: progress towards combination drug therapy.

Published in:

British Journal of Haematology, 2021, v. 194, n. 2, p. 240, doi. 10.1111/bjh.17312

By:

Pace, Betty S.;
Starlard‐Davenport, Athena;
Kutlar, Abdullah

Publication type:

Article

MIR29B mediates epigenetic mechanisms of HBG gene activation.

Published in:

British Journal of Haematology, 2019, v. 186, n. 1, p. 91, doi. 10.1111/bjh.15870

By:

Starlard‐Davenport, Athena;
Smith, Alana;
Vu, Luan;
Li, Biaoru;
Pace, Betty S.

Publication type:

Article

Assessing Patterns of Telehealth Use Among People with Sickle Cell Disease Enrolled in Medicaid During the Start of the COVID-19 Pandemic.

Published in:

Telemedicine & e-Health, 2024, v. 30, n. 7, p. e1971, doi. 10.1089/tmj.2023.0422

By:

Reeves, Sarah L.;
Plegue, Melissa;
Patel, Pooja N.;
Paulukonis, Susan T.;
Horiuchi, Sophia S.;
Zhou, Mei;
Attell, Brandon K.;
Pace, Betty S.;
Snyder, Angela B.;
Plaxco, Allison P.;
Mukhopadhyay, Ayesha;
Smeltzer, Matthew P.;
Ellimoottil, Chandy S.;
Hulihan, Mary

Publication type:

Article

Novel Inducers of Fetal Globin Identified through High Throughput Screening (HTS) Are Active In Vivo in Anemic Baboons and Transgenic Mice.

Published in:

PLoS ONE, 2015, v. 10, n. 12, p. 1, doi. 10.1371/journal.pone.0144660

By:

Boosalis, Michael S.;
Sangerman, Jose I.;
White, Gary L.;
Wolf, Roman F.;
Shen, Ling;
Dai, Yan;
White, Emily;
Makala, Levi H.;
Li, Biaoru;
Pace, Betty S.;
Nouraie, Mehdi;
Faller, Douglas V.;
Perrine, Susan P.

Publication type:

Article

A Cell-Based High-Throughput Screen for Novel Chemical Inducers of Fetal Hemoglobin for Treatment of Hemoglobinopathies.

Published in:

PLoS ONE, 2014, v. 9, n. 9, p. 1, doi. 10.1371/journal.pone.0107006

By:

Peterson, Kenneth R.;
Costa, Flávia C.;
Fedosyuk, Halyna;
Neades, Renee Y.;
Chazelle, Allen M.;
Zelenchuk, Lesya;
Fonteles, Andrea H.;
Dalal, Parmita;
Roy, Anuradha;
Chaguturu, Rathnam;
Li, Biaoru;
Pace, Betty S.

Publication type:

Article

Characterization of Transcription Factor Networks Involved in Umbilical Cord Blood CD34<sup>+</sup> Stem Cells-Derived Erythropoiesis.

Published in:

PLoS ONE, 2014, v. 9, n. 9, p. 1, doi. 10.1371/journal.pone.0107133

By:

Li, Biaoru;
Ding, Lianghao;
Yang, Chinrang;
Kang, Baolin;
Liu, Li;
Story, Michael D.;
Pace, Betty S.

Publication type:

Article

Regulation of Gγ-Globin Gene by ATF2 and Its Associated Proteins through the cAMP-Response Element.

Published in:

PLoS ONE, 2013, v. 8, n. 11, p. 1, doi. 10.1371/journal.pone.0078253

By:

Liu, Li;
Karmakar, Subhradip;
Dhar, Ruby;
Mahajan, Milind;
Choudhury, Alina;
Weissman, Sherman;
Pace, Betty S.

Publication type:

Article

Innovations in Drug Discovery for Sickle Cell Disease Targeting Oxidative Stress and NRF2 Activation—A Short Review.

Published in:

International Journal of Molecular Sciences, 2025, v. 26, n. 9, p. 4192, doi. 10.3390/ijms26094192

By:

Starlard-Davenport, Athena;
Palani, Chithra D.;
Zhu, Xingguo;
Pace, Betty S.

Publication type:

Article

Effects of N-acetylcysteine on dense cell formation in sickle cell disease.

Published in:

American Journal of Hematology, 2003, v. 73, n. 1, p. 26, doi. 10.1002/ajh.10321

By:

Betty S. Pace;
Archil Shartava;
Ardie Pack-Mabien;
Mudhari Mulekar;
Alfredo Ardia;
Steven R. Goodman

Publication type:

Article

Mechanism for fetal hemoglobin induction by hydroxyurea in sickle cell erythroid progenitors.

Published in:

American Journal of Hematology, 2000, v. 65, n. 3, p. 227, doi. 10.1002/1096-8652(200011)65:3<227::AID-AJH9>3.0.CO;2-V

By:

Baliga, B. Surendra;
Pace, Betty S.;
Chen, Hsueh-Hua;
Shah, Arvind K.;
Yang, Yih-Ming

Publication type:

Article