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GM-CSF Upregulated in Rheumatoid Arthritis Reverses Cognitive Impairment and Amyloidosis in Alzheimer Mice.
- Published in:
- Journal of Alzheimer's Disease, 2010, v. 21, n. 2, p. 507, doi. 10.3233/JAD-2010-091471
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- Publication type:
- Article
Caffeine Suppresses Amyloid-β Levels in Plasma and Brain of Alzheimer's Disease Transgenic Mice.
- Published in:
- Journal of Alzheimer's Disease, 2009, v. 17, n. 3, p. 681, doi. 10.3233/JAD-2009-1071
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- Publication type:
- Article
Caffeine Reverses Cognitive Impairment and Decreases Brain Amyloid-β Levels in Aged Alzheimer's Disease Mice.
- Published in:
- Journal of Alzheimer's Disease, 2009, v. 17, n. 3, p. 661, doi. 10.3233/JAD-2009-1087
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- Publication type:
- Article
Apolipoprotein is required for the formation of filamentous amyloid, but not for amorphous Abeta deposition, in an AbetaPP/PS double transgenic mouse model of Alzheimer's disease.
- Published in:
- 2004
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- Publication type:
- journal article
Acute zoster plasma contains elevated amyloid, correlating with Aβ42 and amylin levels, and is amyloidogenic.
- Published in:
- Journal of NeuroVirology, 2020, v. 26, n. 3, p. 422, doi. 10.1007/s13365-020-00830-7
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- Publication type:
- Article
Neuropsychiatric symptoms as a distinguishing factor between memory diagnoses.
- Published in:
- 2020
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- Publication type:
- journal article
Innate Immune System Activation and Neuroinflammation in Down Syndrome and Neurodegeneration: Therapeutic Targets or Partners?
- Published in:
- Frontiers in Aging Neuroscience, 2021, v. 13, p. 1, doi. 10.3389/fnagi.2021.718426
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- Publication type:
- Article
Down Syndrome Biobank Consortium: A perspective.
- Published in:
- Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2024, v. 20, n. 3, p. 2262, doi. 10.1002/alz.13692
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- Publication type:
- Article
The immune cytokine granulocyte‐macrophage colony‐stimulating factor (GM‐CSF) is an effective treatment for both Alzheimer's disease and the viral diseases caused by West Nile Virus and SARS‐CoV‐2 infection, indicating that inflammation and viral infection may be partners and therapeutic co‐targets in many brain disorders
- Published in:
- Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2023, v. 19, n. 21, p. 1, doi. 10.1002/alz.080184
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- Publication type:
- Article
Generation of microglia‐containing APOE4 cerebral organoids as a model of Down syndrome associated Alzheimer's disease.
- Published in:
- Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2023, v. 19, p. 1, doi. 10.1002/alz.080541
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- Publication type:
- Article
GM‐CSF reduces amylin amyloid, inhibits pancreatic apoptosis, and sustains lowered blood glucose levels in the hIAPP mouse model of Type 2 diabetes mellitus, a known risk factor for Alzheimer's disease.
- Published in:
- Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2023, v. 19, p. 1, doi. 10.1002/alz.080349
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- Publication type:
- Article
Alzheimer's disease phenotypes in human induced pluripotent stem cell‐based models of Down syndrome.
- Published in:
- Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2023, v. 19, p. 1, doi. 10.1002/alz.080065
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- Publication type:
- Article
GM‐CSF Treatment Increases the Number of Purkinje Cells in a Mouse Model of Down Syndrome.
- Published in:
- Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2023, v. 19, p. 1, doi. 10.1002/alz.080088
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- Publication type:
- Article
Imipramine treatment reduces Alzheimer's disease neuropathologies in cerebral organoid models of Alzheimer's disease and Down syndrome.
- Published in:
- Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2023, v. 19, p. 1, doi. 10.1002/alz.068273
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- Publication type:
- Article
Increased Expression of Kif11/Kinesin‐5 mRNA Offsets Cognitive Deficits In An Alzheimer's Mouse Model, Blocks Aβ‐Mediated Decreases in Long‐Term Potentiation and Spine Density, and is Associated With Better Cognitive Performance in Alzheimer's Patients
- Published in:
- Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2023, v. 19, p. 1, doi. 10.1002/alz.068051
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- Publication type:
- Article
Elevated levels of mosaic aneuploidy in brain cells and fibroblast cell lines from human Huntington's disease donors and in brain cells from Huntington's disease mouse models.
- Published in:
- Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2023, v. 19, p. 1, doi. 10.1002/alz.067326
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- Publication type:
- Article
The Potential Alzheimer's Disease Drug, GM‐CSF, Enhances the Anti‐Viral Immune Response and Reduces Mortality in a Mouse Model of COVID‐19.
- Published in:
- Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2022, v. 18, n. 10, p. 1, doi. 10.1002/alz.068357
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- Publication type:
- Article
Modeling retinal Alzheimer's disease histopathology with human iPSC‐derived retinal organoids for mechanistic and DRUG DEVELOPMENT studies.
- Published in:
- Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2022, v. 18, n. 10, p. 1, doi. 10.1002/alz.068258
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- Publication type:
- Article
Traumatic Brain Injury Exacerbates Retinal Alzheimer's Disease Histopathology in the TgF344 Rat Model.
- Published in:
- Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2022, v. 18, n. 4, p. 1, doi. 10.1002/alz.068278
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- Publication type:
- Article
GM‐CSF reduces amylin amyloid and prevents pancreatic cell death in the hIAPP mouse model of Type 2 diabetes mellitus, a known risk factor for Alzheimer's disease.
- Published in:
- Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2022, v. 18, n. 4, p. 1, doi. 10.1002/alz.067298
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- Publication type:
- Article
Interrogating the role of APOE4 in Alzheimer's disease and Down syndrome using human induced pluripotent stem cells (hiPSC)‐derived cerebral organoids.
- Published in:
- Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2022, v. 18, n. 3, p. 1, doi. 10.1002/alz.068061
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- Publication type:
- Article
Granulocyte‐Macrophage Colony‐Stimulating Factor Reduces Two Major Pathological Hallmarks of Alzheimer's Disease and Astrogliosis in the TgF344‐AD Rat Model.
- Published in:
- Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2022, v. 18, n. 3, p. 1, doi. 10.1002/alz.067785
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- Publication type:
- Article
Inflammation and innate immune system activation in neurodegeneration, Down syndrome, aging, and infection: Therapeutic target or partner?
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- Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2021, v. 17, p. 1, doi. 10.1002/alz.056681
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- Publication type:
- Article
Identification of small molecule drugs that target apolipoprotein E4‐catalyzed amyloid‐β fibrillization: A new therapeutic approach to Alzheimer's disease.
- Published in:
- Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2021, v. 17, p. 1, doi. 10.1002/alz.054678
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- Publication type:
- Article
Granulocyte‐macrophage colony‐stimulating factor reverses Alzheimer's disease pathology in the tgf344‐AD rat model.
- Published in:
- Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2021, v. 17, n. 3, p. 1, doi. 10.1002/alz.056289
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- Publication type:
- Article
Role of mosaic aneuploidy in the development and progression of Huntington's disease: Developing topics.
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- Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2020, v. 16, n. 11, p. 1, doi. 10.1002/alz.047662
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- Publication type:
- Article
Double‐blind placebo‐controlled trial of the safety and efficacy of GM‐CSF/sargramostim in subjects with mild‐to‐moderate Alzheimer's disease: Human/Human trials: Cognitive enhancement.
- Published in:
- Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2020, v. 16, n. 11, p. 1, doi. 10.1002/alz.046497
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- Publication type:
- Article
Neuropathology and immune biomarker discovery in a rat model of Alzheimer's disease, TgF344‐AD, with controlled cortical injury model of traumatic brain injury: Development of new models and analysis methods/neuroinflammation.
- Published in:
- Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2020, v. 16, n. 11, p. 1, doi. 10.1002/alz.046103
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- Publication type:
- Article
Small molecule inhibitors of apolipoprotein E4‐catalyzed amyloid‐β fibrillization as novel therapeutics for Alzheimer's disease: Development of new models and analysis methods/screening studies/platforms.
- Published in:
- Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2020, v. 16, n. 11, p. 1, doi. 10.1002/alz.043353
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- Publication type:
- Article
Further understanding the connection between Alzheimer's disease and Down syndrome.
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- Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2020, v. 16, n. 7, p. 1065, doi. 10.1002/alz.12112
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- Publication type:
- Article
P4‐032: GM‐CSF REVERSES MEMORY DEFICITS IN NORMAL AGED MICE AND IN THE DP(16)1YEY MOUSE MODEL OF DOWN SYNDROME.
- Published in:
- Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2019, v. 15, p. P1286, doi. 10.1016/j.jalz.2019.06.3691
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- Publication type:
- Article
P1‐311: DEVELOPMENT OF AN INTERNATIONAL POSTERIOR CORTICAL ATROPHY BIOREGISTRY.
- Published in:
- Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2019, v. 15, p. P362, doi. 10.1016/j.jalz.2019.06.866
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- Publication type:
- Article
P4‐203: INTERIM BIOMARKER ANALYSES OF PHASE II STUDY DATA ON SAFETY AND EFFICACY OF GM‐CSF/LEUKINE<sup>®</sup> IN MILD‐TO‐MODERATE AD.
- Published in:
- Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2018, v. 14, p. P1517, doi. 10.1016/j.jalz.2018.07.024
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- Publication type:
- Article
P2‐162: GM‐CSF REVERSES MEMORY DEFICITS IN THE DP16 MOUSE MODEL OF DOWN SYNDROME.
- Published in:
- Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2018, v. 14, p. P730, doi. 10.1016/j.jalz.2018.06.849
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- Publication type:
- Article
P1‐213: ELEVATED LEVELS OF MOSAIC ANEUPLOIDY IN HUNTINGTON'S DISEASE.
- Published in:
- Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2018, v. 14, p. P360, doi. 10.1016/j.jalz.2018.06.218
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- Publication type:
- Article
O1‐12‐01: PHASE II STUDY DATA ON SAFETY AND EFFICACY OF GM‐CSF/LEUKINE<sup>®</sup> IN MILD‐TO‐MODERATE ALZHEIMER'S DISEASE.
- Published in:
- Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2018, v. 14, p. P249, doi. 10.1016/j.jalz.2018.06.2396
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- Publication type:
- Article
The Involvement of Proteases, Protease Inhibitors, and an Acute Phase Response in Alzheimer's Disease <sup>a</sup>.
- Published in:
- Annals of the New York Academy of Sciences, 1992, v. 674, n. 1, p. 161, doi. 10.1111/j.1749-6632.1992.tb27485.x
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- Publication type:
- Article
The utility of age-specific cut-offs for visual rating of medial temporal atrophy in classifying Alzheimer's disease, MCI and cognitively normal elderly subjects.
- Published in:
- Frontiers in Aging Neuroscience, 2013, v. 5, p. 1, doi. 10.3389/fnagi.2013.00047
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- Publication type:
- Article
The potential of BACE inhibitors for Alzheimer's therapy.
- Published in:
- Nature Biotechnology, 2000, v. 18, n. 2, p. 125, doi. 10.1038/72477
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- Publication type:
- Article
INTERIM REPORT OF A PHASE 2 PILOT SAFETY AND EFFICACY TRIAL OF GM-CSF/LEUKINE® IN MILD-TO-MODERATE ALZHEIMER'S DISEASE.
- Published in:
- Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2017, v. 13, p. P1572, doi. 10.1016/j.jalz.2017.07.735
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- Publication type:
- Article
FOLATE PREVENTS THE DETRIMENTAL EFFECTS OF OLIGOMERIC Aβ ON INSULIN RECEPTOR LOCALIZATION AND FUNCTION AND LONG-TERM POTENTIATION.
- Published in:
- Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2017, v. 13, p. P989, doi. 10.1016/j.jalz.2017.06.1352
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- Publication type:
- Article
ABNORMAL CHROMOSOME COPY NUMBER AND ASSOCIATED NEURONAL CELL DEATH IN FRONTOTEMPORAL LOBAR DEGENERATION.
- Published in:
- Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2017, v. 13, p. P661, doi. 10.1016/j.jalz.2017.06.790
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- Publication type:
- Article
SCREENING FOR INHIBITORS OF APOE4-CATALYZED Aβ OLIGOMER/FILAMENT FORMATION: A NOVEL APPROACH TO ALZHEIMER’S DISEASE DRUG DISCOVERY.
- Published in:
- Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2017, v. 13, p. P662, doi. 10.1016/j.jalz.2017.06.793
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- Publication type:
- Article
INCREASED GENOMIC INSTABILITY AND CORRELATED APOPTOSIS ARE ASSOCIATED WITH COGNITIVE IMPAIRMENT IN NEURODEGENERATIVE DISEASES.
- Published in:
- Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2016, v. 12, p. P655, doi. 10.1016/j.jalz.2016.06.1484
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- Publication type:
- Article
TYPE 3 DIABETES IN ALZHEIMER’S DISEASE: AB-MEDIATED INHIBITION OF EG5/KINESIN 5 LEADS TO INSULIN RECEPTOR AND GLUCOSE TRANSPORTER MIS-LOCALIZATION AND DYSFUNCTION.
- Published in:
- Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2016, v. 12, p. P338, doi. 10.1016/j.jalz.2016.06.621
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- Publication type:
- Article
Association of aneuploidy with multiple neurodegenerative diseases and its possible involvement in the progression of cognitive decline.
- Published in:
- Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2015, v. 11, n. 7, p. P338, doi. 10.1016/j.jalz.2015.06.202
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- Publication type:
- Article
Down syndrome and Alzheimer's disease: Common pathways, common goals.
- Published in:
- Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2015, v. 11, n. 6, p. 700, doi. 10.1016/j.jalz.2014.10.007
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- Publication type:
- Article
Comparing new templates and atlas-based segmentations in the volumetric analysis of brain magnetic resonance images for diagnosing Alzheimer’s disease
- Published in:
- Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2012, v. 8, n. a5, p. 399, doi. 10.1016/j.jalz.2011.07.002
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- Publication type:
- Article
Aß inhibition of kinesin 5 induces neurotransmitter and neurotrophin receptor mislocalization and dysfunction
- Published in:
- 2012
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- Publication type:
- Abstract
Genomic damage induced by lipoproteins/cholesterol: Implications for Alzheimer's and cardiovascular disease
- Published in:
- 2012
- By:
- Publication type:
- Abstract