Works by PAULE, MERLE G.

Results: 45

Disruption of blastomeric F-actin: a potential early biomarker of developmental toxicity in zebrafish.

Published in:

Molecular & Cellular Biochemistry, 2011, v. 353, n. 1/2, p. 283, doi. 10.1007/s11010-011-0797-2

By:

Kanungo, Jyotshnabala;
Paule, Merle G.

Publication type:

Article

Developmental toxicity assay using high content screening of zebrafish embryos.

Published in:

Journal of Applied Toxicology, 2015, v. 35, n. 3, p. 261, doi. 10.1002/jat.3029

By:

Lantz‐McPeak, Susan;
Guo, Xiaoqing;
Cuevas, Elvis;
Dumas, Melanie;
Newport, Glenn D.;
Ali, Syed F.;
Paule, Merle G.;
Kanungo, Jyotshna

Publication type:

Article

Ketamine attenuates cytochrome p450 aromatase gene expression and estradiol-17β levels in zebrafish early life stages.

Published in:

Journal of Applied Toxicology, 2014, v. 34, n. 5, p. 480, doi. 10.1002/jat.2888

By:

Trickler, William J.;
Guo, Xiaoqing;
Cuevas, Elvis;
Ali, Syed F.;
Paule, Merle G.;
Kanungo, Jyotshna

Publication type:

Article

Application of microPET imaging approaches in the study of pediatric anesthetic-induced neuronal toxicity.

Published in:

Journal of Applied Toxicology, 2013, v. 33, n. 9, p. 861, doi. 10.1002/jat.2857

By:

Zhang, Xuan;
Paule, Merle G.;
Wang, Cheng;
Slikker, William

Publication type:

Article

Ketamine induces motor neuron toxicity and alters neurogenic and proneural gene expression in zebrafish.

Published in:

Journal of Applied Toxicology, 2013, v. 33, n. 6, p. 410, doi. 10.1002/jat.1751

By:

Kanungo, Jyotshna;
Cuevas, Elvis;
Ali, Syed F.;
Paule, Merle G.

Publication type:

Article

Systems biology approaches for toxicology.

Published in:

Journal of Applied Toxicology, 2007, v. 27, n. 3, p. 201, doi. 10.1002/jat.1207

By:

Slikker, Jr., William;
Paule, Merle G.;
Wright, Linnzi K. M.;
Patterson, Tucker A.;
Cheng Wang

Publication type:

Article

MicroPET/CT Imaging of [18F]-FEPPA in the Nonhuman Primate: A Potential Biomarker of Pathogenic Processes Associated with Anesthetic-Induced Neurotoxicity.

Published in:

ISRN Anesthesiology, 2012, p. 1, doi. 10.5402/2012/261640

By:

Zhang, Xuan;
Paule, Merle G.;
Newport, Glenn D.;
Liu, Fang;
Callicott, Ralph;
Liu, Shuliang;
Berridge, Marc S.;
Apana, Scott M.;
Slikker Jr., William;
Wang, Cheng

Publication type:

Article

The Reinforcing Effects of Nicotine in Humans and Nonhuman Primates: A Review of Intravenous Self-Administration Evidence and Future Directions for Research.

Published in:

2015

By:

Goodwin, Amy K.;
Takato Hiranita;
Paule, Merle G.;
Hiranita, Takato

Publication type:

journal article

Prolonged exposure to ketamine increases neurodegeneration in the developing monkey brain

Published in:

International Journal of Developmental Neuroscience, 2009, v. 27, n. 7, p. 727, doi. 10.1016/j.ijdevneu.2009.06.010

By:

Zou, Xiaoju;
Patterson, Tucker A.;
Divine, Rebecca L.;
Sadovova, Natalya;
Zhang, Xuan;
Hanig, Joseph P.;
Paule, Merle G.;
Slikker, William;
Wang, Cheng

Publication type:

Article

Protein Kinases and Parkinson's Disease.

Published in:

International Journal of Molecular Sciences, 2016, v. 17, n. 9, p. 1585, doi. 10.3390/ijms17091585

By:

Mehdi, Syed Jafar;
Rosas-Hernandez, Hector;
Cuevas, Elvis;
Lantz, Susan M.;
Barger, Steven W.;
Sarkar, Sumit;
Paule, Merle G.;
Ali, Syed F.;
Imam, Syed Z.

Publication type:

Article

Brain microvessel endothelial cells responses to gold nanoparticles: In vitro pro-inflammatory mediators and permeability.

Published in:

Nanotoxicology, 2011, v. 5, n. 4, p. 479, doi. 10.3109/17435390.2010.540356

By:

Trickler, William J.;
Lantz, Susan M.;
Murdock, Richard C.;
Schrand, Amanda M.;
Robinson, Bonnie L.;
Newport, Glenn D.;
Schlager, John J.;
Oldenburg, Steven J.;
Paule, Merle G.;
Slikker Jr, William;
Hussain, Saber M.;
Ali, Syed F.

Publication type:

Article

Analysis of methylphenidate and its metabolite ritalinic acid in monkey plasma by liquid chromatography/electrospray ionization mass spectrometry.

Published in:

Rapid Communications in Mass Spectrometry: RCM, 2000, v. 14, n. 8, p. 619, doi. 10.1002/(SICI)1097-0231(20000430)14:8<619::AID-RCM916>3.0.CO;2-2

By:

Doerge, Daniel R.;
Matthew Fogle, C.;
Paule, Merle G.;
McCullagh, Michael;
Bajic, Steve

Publication type:

Article

Meal-Induced Increase in Plasma Gastrin Immunoreactivity in the Rhesus Monkey (Macaca mulatta).

Published in:

American Journal of Primatology, 1989, v. 18, n. 4, p. 315, doi. 10.1002/ajp.1350180405

By:

Scallet, Andrew C.;
McKay, Daniel;
Baley, John R.;
Ali, Syed F.;
Paule, Merle G.;
Slikker, Jr., William;
Rayford, Phillip L.

Publication type:

Article

Prenatal trace elements mixture is associated with learning deficits on a behavioral acquisition task among young children.

Published in:

New Directions for Child & Adolescent Development, 2022, v. 2022, n. 181/182, p. 53, doi. 10.1002/cad.20458

By:

Merced‐Nieves, Francheska M.;
Chelonis, John;
Pantic, Ivan;
Schnass, Lourdes;
Téllez‐Rojo, Martha M.;
Braun, Joseph M.;
Paule, Merle G.;
Wright, Rosalind J.;
Wright, Robert O.;
Curtin, Paul

Publication type:

Article

Translational Biomarkers of Neurotoxicity: A Health and Environmental Sciences Institute Perspective on the Way Forward.

Published in:

Toxicological Sciences, 2015, v. 148, n. 2, p. 332, doi. 10.1093/toxsci/kfv188

By:

Roberts, Ruth A.;
Aschner, Michael;
Calligaro, David;
Guilarte, Tomas R.;
Hanig, Joseph P.;
Herr, David W.;
Hudzik, Thomas J.;
Jeromin, Andreas;
Kallman, Mary J.;
Liachenko, Serguei;
Lynch III, James J.;
Miller, Diane B.;
Moser, Virginia C.;
O'Callaghan, James P.;
Slikker Jr, William;
Paule, Merle G.

Publication type:

Article

Potential Adverse Effects of Prolonged Sevoflurane Exposure on Developing Monkey Brain: From Abnormal Lipid Metabolism to Neuronal Damage.

Published in:

Toxicological Sciences, 2015, v. 147, n. 2, p. 562, doi. 10.1093/toxsci/kfv150

By:

Fang Liu;
Rainosek, Shuo W.;
Frisch-Daiello, Jessica L.;
Patterson, Tucker A.;
Paule, Merle G.;
Slikker Jr., William;
Cheng Wang;
Xianlin Han

Publication type:

Article

Quantitative Assessment of MRI T2 Response to Kainic Acid Neurotoxicity in Rats in vivo.

Published in:

Toxicological Sciences, 2015, v. 146, n. 1, p. 183, doi. 10.1093/toxsci/kfv083

By:

Liachenko, Serguei;
Ramu, Jaivijay;
Konak, Tetyana;
Paule, Merle G.;
Hanig, Joseph

Publication type:

Article

Ketamine-Induced Neuronal Damage and Altered N-Methyl-d-Aspartate Receptor Function in Rat Primary Forebrain Culture.

Published in:

Toxicological Sciences, 2013, v. 131, n. 2, p. 548, doi. 10.1093/toxsci/kfs296

By:

Liu, Fang;
Patterson, Tucker A.;
Sadovova, Natalya;
Zhang, Xuan;
Liu, Shuliang;
Zou, Xiaoju;
Hanig, Joseph P.;
Paule, Merle G.;
Slikker, William;
Wang, Cheng

Publication type:

Article

Silver Nanoparticle Induced Blood-Brain Barrier Inflammation and Increased Permeability in Primary Rat Brain Microvessel Endothelial Cells.

Published in:

Toxicological Sciences, 2010, v. 118, n. 1, p. 160, doi. 10.1093/toxsci/kfq244

By:

Trickler, William J.;
Lantz, Susan M.;
Murdock, Richard C.;
Schrand, Amanda M.;
Robinson, Bonnie L.;
Newport, Glenn D.;
Schlager, John J.;
Oldenburg, Steven J.;
Paule, Merle G.;
Slikker, William;
Hussain, Saber M.;
Ali, Syed F.

Publication type:

Article

A Minimally Invasive, Translational Biomarker of Ketamine-Induced Neuronal Death in Rats: microPET Imaging Using 18F-Annexin V.

Published in:

Toxicological Sciences, 2009, v. 111, n. 2, p. 355, doi. 10.1093/toxsci/kfp167

By:

Xuan Zhang;
Paule, Merle G.;
Newport, Glenn D.;
Xiaoju Zou;
Sadovova, Natalya;
Berridge, Marc S.;
Apana, Scott M.;
Hanig, Joseph P.;
Slikker Jr., William;
Cheng Wang

Publication type:

Article

Potential Neurotoxicity of Ketamine in the Developing Rat Brain.

Published in:

Toxicological Sciences, 2009, v. 108, n. 1, p. 149, doi. 10.1093/toxsci/kfn270

By:

Xiaoju Zou;
Tucker A. Patterson;
Natalya Sadovova;
Nathan C. Twaddle;
Daniel R. Doerge;
Xuan Zhang;
Xin Fu;
Joseph P. Hanig;
Merle G. Paule;
William Slikker;
Cheng Wang

Publication type:

Article

Ketamine-Induced Neuronal Cell Death in the Perinatal Rhesus Monkey.

Published in:

Toxicological Sciences, 2007, v. 98, n. 1, p. 145, doi. 10.1093/toxsci/kfm084

By:

William Slikker;
Xiaoju Zou;
Charlotte E. Hotchkiss;
Rebecca L. Divine;
Natalya Sadovova;
Nathan C. Twaddle;
Daniel R. Doerge;
Andrew C. Scallet;
Tucker A. Patterson;
Joseph P. Hanig;
Merle G. Paule;
Cheng Wang

Publication type:

Article

Blockade of N-Methyl-D-Aspartate Receptors by Ketamine Produces Loss of Postnatal Day 3 Monkey Frontal Cortical Neurons in Culture.

Published in:

Toxicological Sciences, 2006, v. 91, n. 1, p. 192, doi. 10.1093/toxsci/kfj144

By:

Cheng Wang;
Sadovova, Natalya;
Hotchkiss, Charlotte;
Xin Fu;
Scallet, Andrew C.;
Patterson, Tucker A.;
Hanig, Joseph;
Paule, Merle G.;
Slikker Jr., William

Publication type:

Article

Ontogeny of the N-Methyl-D-Aspartate (NMDA) Receptor System and Susceptibility to Neurotoxicity.

Published in:

Toxicological Sciences, 2002, v. 68, n. 1, p. 9, doi. 10.1093/toxsci/68.1.9

By:

Haberny, Kathleen A.;
Paule, Merle G.;
Scallet, Andrew C.;
Sistare, Frank D.;
Lester, David S.;
Hanig, Joseph P.;
Slikker Jr., William

Publication type:

Article

Cognitive Tests: Interpretation for Neurotoxicity? (Workshop Summary).

Published in:

Toxicological Sciences, 2000, v. 58, n. 2, p. 222, doi. 10.1093/toxsci/58.2.222

By:

Slikker Jr., William;
Beck, Barbara D.;
Cory-Slechta, Deborah A.;
Paule, Merle G.;
Anger, W. Kent;
Bellinger, David

Publication type:

Article

Effects of silver nanoparticles on human and rat embryonic neural stem cells.

Published in:

Frontiers in Neuroscience, 2015, v. 9, p. 1, doi. 10.3389/fnins.2015.00115

By:

Fang Liu;
Mahmood, Meena;
Yang Xu;
Watanabe, Fumiya;
Biris, Alexandru S.;
Hansen, Deborah K.;
Inselman, Amy;
Casciano, Daniel;
Patterson, Tucker A.;
Paule, Merle G.;
Slikker Jr., William;
Cheng Wang

Publication type:

Article

Chronic Exposure to NMDA Receptor and Sodium Channel Blockers during Development in Monkeys and Rats.

Published in:

Annals of the New York Academy of Sciences, 2003, v. 993, n. 1, p. 116, doi. 10.1111/j.1749-6632.2003.tb07519.x

By:

PAULE, MERLE G.;
FOGLE, C. MATTHEW;
ALLEN, RICHARD R.;
PEARSON, EDWIN C.;
HAMMOND, TIMOTHY G.;
POPKE, E. JON

Publication type:

Article

Effects of Chronic NMDA Receptor and Fast Sodium Channel Blockade during Development on the Acquisition of Visual Discriminations and Learning Abilities in Rhesus Monkeys.

Published in:

Annals of the New York Academy of Sciences, 2001, v. 939, n. 1, p. 237, doi. 10.1111/j.1749-6632.2001.tb03630.x

By:

PAULE, MERLE G.;
POPKE, E. JON;
ALLEN, RICHARD R.;
PEARSON, EDWIN;
HAMMOND, TIM

Publication type:

Article

Development of a Physiologically Based Model to Describe the Pharmacokinetics of Methylphenidate in Juvenile and Adult Humans and Nonhuman Primates.

Published in:

PLoS ONE, 2014, v. 9, n. 9, p. 1, doi. 10.1371/journal.pone.0106101

By:

Yang, Xiaoxia;
Morris, Suzanne M.;
Gearhart, Jeffery M.;
Ruark, Christopher D.;
Paule, Merle G.;
Slikker Jr, William;
Mattison, Donald R.;
Vitiello, Benedetto;
Twaddle, Nathan C.;
Doerge, Daniel R.;
Young, John F.;
Fisher, Jeffrey W.

Publication type:

Article

Neuroprotective Efficacy of a New Brain-Penetrating C-Abl Inhibitor in a Murine Parkinson’s Disease Model

Published in:

PLoS ONE, 2013, v. 8, n. 5, p. 1, doi. 10.1371/journal.pone.0065129

By:

Imam, Syed Z.;
Trickler, William;
Kimura, Shinya;
Binienda, Zbigniew K.;
Paule, Merle G.;
Slikker Jr, William;
Li, Senlin;
Clark, Robert A.;
Ali, Syed F.

Publication type:

Article

Role of Neural Stem Cell Activity in Postweaning Development of the Sexually Dimorphic Nucleus of the Preoptic Area in Rats.

Published in:

PLoS ONE, 2013, v. 8, n. 1, p. 1, doi. 10.1371/journal.pone.0054927

By:

Zhen He;
Ferguson, Sherry A.;
Li Cui;
Greenfield Jr., L. John;
Paule, Merle G.

Publication type:

Article

Effects of Chronic in Utero Exposure to Cocaine on Behavioral Adaptability in Rhesus Monkey Offspring When Examined in Adulthood.

Published in:

Annals of the New York Academy of Sciences, 2000, v. 914, n. 1, p. 412, doi. 10.1111/j.1749-6632.2000.tb05215.x

By:

PAULE, MERLE G.;
GILLAM, MICHAEL P.;
ALLEN, RICHARD R.;
CHELONIS, JOHN J.

Publication type:

Article

Development of a Nonhuman Primate Model for Studying the Consequences of Long-Term Neuroprotectant Administration on Complex Brain Functions in Developing Animals.

Published in:

Annals of the New York Academy of Sciences, 1999, v. 890, n. 1, p. 470, doi. 10.1111/j.1749-6632.1999.tb08027.x

By:

PAULE, MERLE G.;
POPKE, E. JON;
PEARSON, EDWIN;
HAMMOND, TIM

Publication type:

Article

The Effects of Cocaine on Nonhuman Primate Brain Function Are Age Dependenta.

Published in:

Annals of the New York Academy of Sciences, 1998, v. 844, n. 1, p. 178, doi. 10.1111/j.1749-6632.1998.tb08232.x

By:

PAULE, MERLE G.;
GILLAM, MICHAEL P.;
MORRIS, PAUL

Publication type:

Article

Acute Effects of Dexfenfluramine (d-FEN) and Methylenedioxymethamphetamine (MDMA) before and after Short-Course, High-Dose Treatment.

Published in:

Annals of the New York Academy of Sciences, 1998, v. 844, n. 1, p. 183, doi. 10.1111/j.1749-6632.1998.tb08233.x

By:

FREDERICK, DAVID L.;
ALI, SYED F.;
GILLAM, MICHAEL P.;
GOSSETT, JEFF;
SLIKKER, WILLIAM;
PAULE, MERLE G.

Publication type:

Article

Chronic Cocaine Exposure throughout Gestation in the Rhesus Monkey.

Published in:

Annals of the New York Academy of Sciences, 1996, v. 801, n. 1, p. 301, doi. 10.1111/j.1749-6632.1996.tb17450.x

By:

PAULE, MERLE G.;
GILLAM, MICHAEL P.;
BINIENDA, ZBIGNIEW;
MORRIS, PAUL

Publication type:

Article

Characterization of Biaxial Stretch as an In Vitro Model of Traumatic Brain Injury to the Blood-Brain Barrier.

Published in:

Molecular Neurobiology, 2018, v. 55, n. 1, p. 258, doi. 10.1007/s12035-017-0738-5

By:

Rosas-Hernandez, Hector;
Cuevas, Elvis;
Escudero-Lourdes, Claudia;
Lantz, Susan M.;
Gomez-Crisostomo, Nancy P.;
Sturdivant, Nasya M.;
Balachandran, Kartik;
Imam, Syed Z.;
Slikker, William;
Paule, Merle G.;
Ali, Syed F.

Publication type:

Article

A Working Module for the Neurovascular Unit in the Sexually Dimorphic Nucleus of the Preoptic Area.

Published in:

Molecular Neurobiology, 2018, v. 55, n. 1, p. 156, doi. 10.1007/s12035-017-0729-6

By:

He, Zhen;
Cui, Li;
Ferguson, Sherry A.;
Paule, Merle G.

Publication type:

Article

Downregulation of 14-3-3 Proteins in a Kainic Acid-Induced Neurotoxicity Model.

Published in:

Molecular Neurobiology, 2018, v. 55, n. 1, p. 122, doi. 10.1007/s12035-017-0724-y

By:

Smani, Danyal;
Sarkar, Sumit;
Raymick, James;
Kanungo, Jyotshna;
Paule, Merle G.;
Gu, Qiang

Publication type:

Article

Porcine brain microvessel endothelial cells show pro-inflammatory response to the size and composition of metallic nanoparticles.

Published in:

Drug Metabolism Reviews, 2014, v. 46, n. 2, p. 224, doi. 10.3109/03602532.2013.873450

By:

Trickler, William J.;
Lantz-McPeak, Susan M.;
Robinson, Bonnie L.;
Paule, Merle G.;
Slikker, William;
Biris, Alexandru S.;
Schlager, John J.;
Hussain, Saber M.;
Kanungo, Jyotshna;
Gonzalez, Carmen;
Ali, Syed F.

Publication type:

Article

Cytotoxicity profile of pristine graphene on brain microvascular endothelial cells.

Published in:

Journal of Applied Toxicology, 2019, v. 39, n. 7, p. 966, doi. 10.1002/jat.3786

By:

Rosas‐Hernandez, Hector;
Ramirez‐Lee, Manuel A.;
Cuevas, Elvis;
Lantz, Susan M.;
Imam, Syed Z.;
Paule, Merle G.;
Ali, Syed F.;
Escudero‐Lourdes, Claudia;
Majeed, Waqar;
Bourdo, Shawn E.;
Biris, Alexandru S.

Publication type:

Article

Cyclosporine exacerbates ketamine toxicity in zebrafish: Mechanistic studies on drug-drug interaction.

Published in:

Journal of Applied Toxicology, 2017, v. 37, n. 12, p. 1438, doi. 10.1002/jat.3488

By:

Robinson, Bonnie L.;
Dumas, Melanie;
Ali, Syed F.;
Paule, Merle G.;
Gu, Qiang;
Kanungo, Jyotshna

Publication type:

Article

Acetyl L-carnitine targets adenosine triphosphate synthase in protecting zebrafish embryos from toxicities induced by verapamil and ketamine: An in vivo assessment.

Published in:

Journal of Applied Toxicology, 2017, v. 37, n. 2, p. 192, doi. 10.1002/jat.3340

By:

Guo, Xiaoqing;
Dumas, Melanie;
Robinson, Bonnie L.;
Ali, Syed F.;
Paule, Merle G.;
Gu, Qiang;
Kanungo, Jyotshna

Publication type:

Article

Positron emission tomography with [18F]FLT revealed sevoflurane-induced inhibition of neural progenitor cell expansion in vivo.

Published in:

Frontiers in Neurology, 2014, v. 5, p. 1, doi. 10.3389/fneur.2014.00234

By:

Shuliang Liu;
Paule, Merle G.;
Xuan Zhang;
Newport, Glenn D.;
Patterson, Tucker A.;
Apana, Scott M.;
Berridge, Marc S.;
Maisha, Mackean P.;
Slikker Jr., William;
Cheng Wang

Publication type:

Article

Preclinical Assessment of Ketamine.

Published in:

CNS Neuroscience & Therapeutics, 2013, v. 19, n. 6, p. 448, doi. 10.1111/cns.12079

By:

Wang, Cheng;
Liu, Fang;
Patterson, Tucker A.;
Paule, Merle G.;
Slikker, William

Publication type:

Article