Works by Pękala, Elżbieta

Results: 57
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    In vitro safety evaluation of (6-methoxy-9-oxo-9H-xanthen-2-yl)methyl (E)-3-(2,4-dimethoxyphenyl)acrylate (K-116) – the novel potential UV filter designed by means of a double chromophore strategy.

    Published in:
    Xenobiotica, 2024, v. 54, n. 6, p. 266, doi. 10.1080/00498254.2024.2363332
    By:
    • Popiół, Justyna;
    • Gunia-Krzyżak, Agnieszka;
    • Słoczyńska, Karolina;
    • Piska, Kamil;
    • Kocot, Natalia;
    • Żelaszczyk, Dorota;
    • Krupa, Anna;
    • Wójcik-Pszczoła, Katarzyna;
    • Marona, Henryk;
    • Pękala, Elżbieta
    Publication type:
    Article
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    Synthesis and biological evaluation of 2-fluoro and 3-trifluoromethyl-phenyl-piperazinylalkyl derivatives of 1H-imidazo[2,1-f]purine-2,4(3H,8H)-dione as potential antidepressant agents.

    Published in:
    Journal of Enzyme Inhibition & Medicinal Chemistry, 2016, v. 31, p. 10, doi. 10.1080/14756366.2016.1198902
    By:
    • Zagórska, Agnieszka;
    • Bucki, Adam;
    • Kołaczkowski, Marcin;
    • Siwek, Agata;
    • Głuch-Lutwin, Monika;
    • Starowicz, Gabriela;
    • Kazek, Grzegorz;
    • Partyka, Anna;
    • Wesołowska, Anna;
    • Słoczyńska, Karolina;
    • Pękala, Elżbieta;
    • Pawłowski, Maciej
    Publication type:
    Article
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    Synthesis and biological evaluation of 2-fluoro and 3-trifluoromethyl-phenyl-piperazinylalkyl derivatives of 1 H -imidazo[2,1- f ]purine-2,4(3 H ,8 H )-dione as potential antidepressant agents.

    Published in:
    Journal of Enzyme Inhibition & Medicinal Chemistry, 2016, v. 31, p. 10, doi. 10.1080/14756366.2016.1198902
    By:
    • Zagórska, Agnieszka;
    • Bucki, Adam;
    • Kołaczkowski, Marcin;
    • Siwek, Agata;
    • Głuch-Lutwin, Monika;
    • Starowicz, Gabriela;
    • Kazek, Grzegorz;
    • Partyka, Anna;
    • Wesołowska, Anna;
    • Słoczyńska, Karolina;
    • Pękala, Elżbieta;
    • Pawłowski, Maciej
    Publication type:
    Article
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    1-(Arylsulfonyl-isoindol-2-yl)piperazines as 5-HT 6 R Antagonists: Mechanochemical Synthesis, In Vitro Pharmacological Properties and Glioprotective Activity.

    Published in:
    Biomolecules (2218-273X), 2023, v. 13, n. 1, p. 12, doi. 10.3390/biom13010012
    By:
    • Canale, Vittorio;
    • Trybała, Wojciech;
    • Chaumont-Dubel, Séverine;
    • Koczurkiewicz-Adamczyk, Paulina;
    • Satała, Grzegorz;
    • Bento, Ophélie;
    • Blicharz-Futera, Klaudia;
    • Bantreil, Xavier;
    • Pękala, Elżbieta;
    • Bojarski, Andrzej J.;
    • Lamaty, Frédéric;
    • Marin, Philippe;
    • Zajdel, Paweł
    Publication type:
    Article
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    Anti-Helicobacter pylori activities of selected N-substituted cinnamamide derivatives evaluated on reference and clinical bacterial strains.

    Published in:
    Journal of Antibiotics, 2018, v. 71, n. 5, p. 543, doi. 10.1038/s41429-018-0027-1
    By:
    • Klesiewicz, Karolina;
    • Karczewska, Elżbieta;
    • Nowak, Paweł;
    • Skiba-Kurek, Iwona;
    • Sito, Edward;
    • Pańczyk, Katarzyna;
    • Koczurkiewicz, Paulina;
    • Żelaszczyk, Dorota;
    • Pękala, Elżbieta;
    • Waszkielewicz, Anna M.;
    • Budak, Alicja;
    • Marona, Henryk;
    • Gunia-Krzyżak, Agnieszka
    Publication type:
    Article
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    New Arylpiperazinylalkyl Derivatives of 8-Alkoxy-purine-2,6-dione and Dihydro[1,3]oxazolo[2,3- f]purinedione Targeting the Serotonin 5-HT<sub>1A</sub>/5-HT<sub>2A</sub>/5-HT<sub>7</sub> and Dopamine D<sub>2</sub> Receptors.

    Published in:
    Archiv der Pharmazie, 2015, v. 348, n. 4, p. 242, doi. 10.1002/ardp.201500015
    By:
    • Chłoń ‐ Rzepa, Grażyna;
    • Zagórska, Agnieszka;
    • Bucki, Adam;
    • Kołaczkowski, Marcin;
    • Pawłowski, Maciej;
    • Satała, Grzegorz;
    • Bojarski, Andrzej J.;
    • Partyka, Anna;
    • Wesołowska, Anna;
    • Pękala, Elżbieta;
    • Słoczyńska, Karolina
    Publication type:
    Article
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    Biotransformation of 4‐fluoro‐N‐(1‐{2‐[(propan‐2‐yl)phenoxy]ethyl}‐8‐azabicyclo[3.2.1]octan‐3‐yl)‐benzenesulfonamide, a novel potent 5‐HT<sub>7</sub> receptor antagonist with antidepressant‐like and anxiolytic properties: In vitro and in silico approach

    Published in:
    Journal of Biochemical & Molecular Toxicology, 2018, v. 32, n. 5, p. 1, doi. 10.1002/jbt.22048
    By:
    • Słoczyńska, Karolina;
    • Wójcik‐Pszczoła, Katarzyna;
    • Canale, Vittorio;
    • Żmudzki, Paweł;
    • Zajdel, Paweł;
    • Pękala, Elżbieta
    Publication type:
    Article
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    Impact of N-Alkylamino Substituents on Serotonin Receptor (5-HTR) Affinity and Phosphodiesterase 10A (PDE10A) Inhibition of Isoindole-1,3-dione Derivatives.

    Published in:
    Molecules, 2020, v. 25, n. 17, p. 3868, doi. 10.3390/molecules25173868
    By:
    • Czopek, Anna;
    • Partyka, Anna;
    • Bucki, Adam;
    • Pawłowski, Maciej;
    • Kołaczkowski, Marcin;
    • Siwek, Agata;
    • Głuch-Lutwin, Monika;
    • Koczurkiewicz, Paulina;
    • Pękala, Elżbieta;
    • Jaromin, Anna;
    • Tyliszczak, Bożena;
    • Wesołowska, Anna;
    • Zagórska, Agnieszka;
    • Jampilek, Josef
    Publication type:
    Article
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    Discovery of Novel UV-Filters with Favorable Safety Profiles in the 5-Arylideneimidazolidine-2,4-dione Derivatives Group.

    Published in:
    Molecules, 2019, v. 24, n. 12, p. 2321, doi. 10.3390/molecules24122321
    By:
    • Popiół, Justyna;
    • Gunia-Krzyżak, Agnieszka;
    • Piska, Kamil;
    • Żelaszczyk, Dorota;
    • Koczurkiewicz, Paulina;
    • Słoczyńska, Karolina;
    • Wójcik-Pszczoła, Katarzyna;
    • Krupa, Anna;
    • Kryczyk-Poprawa, Agata;
    • Żesławska, Ewa;
    • Nitek, Wojciech;
    • Żmudzki, Paweł;
    • Marona, Henryk;
    • Pękala, Elżbieta
    Publication type:
    Article
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    Discovery of New 3-(Benzo[ b ]Thiophen-2-yl)Pyrrolidine-2,5-Dione Derivatives as Potent Antiseizure and Antinociceptive Agents—In Vitro and In Vivo Evaluation.

    Published in:
    Pharmaceuticals (14248247), 2024, v. 17, n. 11, p. 1532, doi. 10.3390/ph17111532
    By:
    • Rapacz, Anna;
    • Jakubiec, Marcin;
    • Abram, Michał;
    • Jasiński, Jakub;
    • Chrzan, Karolina;
    • Góra, Małgorzata;
    • Dziubina, Anna;
    • Wójcik-Pszczoła, Katarzyna;
    • Koczurkiewicz-Adamczyk, Paulina;
    • Ciepiela, Katarzyna;
    • Pękala, Elżbieta;
    • Obniska, Jolanta;
    • Kamiński, Krzysztof
    Publication type:
    Article
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    Przeciwciała monoklonalne w terapii celowanej.

    Published in:
    Advances in Hygiene & Experimental Medicine / Postepy Higieny i Medycyny Doswiadczalnej, 2012, v. 66, p. 663
    By:
    • Powroźnik, Beata;
    • Kubowicz, Paulina;
    • Pękala, Elżbieta
    Publication type:
    Article
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    S(+)-(2E)-N-(2-Hydroxypropyl)-3-Phenylprop-2-Enamide (KM-568): A Novel Cinnamamide Derivative with Anticonvulsant Activity in Animal Models of Seizures and Epilepsy.

    Published in:
    International Journal of Molecular Sciences, 2020, v. 21, n. 12, p. 4372, doi. 10.3390/ijms21124372
    By:
    • Gunia-Krzyżak, Agnieszka;
    • Żesławska, Ewa;
    • Słoczyńska, Karolina;
    • Żelaszczyk, Dorota;
    • Sowa, Aleksandra;
    • Koczurkiewicz-Adamczyk, Paulina;
    • Popiół, Justyna;
    • Nitek, Wojciech;
    • Pękala, Elżbieta;
    • Marona, Henryk
    Publication type:
    Article
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    A Novel, Pan-PDE Inhibitor Exerts Anti-Fibrotic Effects in Human Lung Fibroblasts via Inhibition of TGF-β Signaling and Activation of cAMP/PKA Signaling.

    Published in:
    International Journal of Molecular Sciences, 2020, v. 21, n. 11, p. 4008, doi. 10.3390/ijms21114008
    By:
    • Wójcik-Pszczoła, Katarzyna;
    • Chłoń-Rzepa, Grażyna;
    • Jankowska, Agnieszka;
    • Ślusarczyk, Marietta;
    • Ferdek, Paweł E;
    • Kusiak, Agnieszka A;
    • Świerczek, Artur;
    • Pociecha, Krzysztof;
    • Koczurkiewicz-Adamczyk, Paulina;
    • Wyska, Elżbieta;
    • Pękala, Elżbieta;
    • Gosens, Reinoud
    Publication type:
    Article
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    Synthesis and Pharmacological Evaluation of Novel Silodosin-Based Arylsulfonamide Derivatives as α<sub>1A</sub>/α<sub>1D</sub>-Adrenergic Receptor Antagonist with Potential Uroselective Profile.

    Published in:
    Molecules, 2018, v. 23, n. 9, p. 2175, doi. 10.3390/molecules23092175
    By:
    • Canale, Vittorio;
    • Rak, Aleksandra;
    • Kotańska, Magdalena;
    • Knutelska, Joanna;
    • Siwek, Agata;
    • Bednarski, Marek;
    • Nowiński, Leszek;
    • Zygmunt, Małgorzata;
    • Koczurkiewicz, Paulina;
    • Pękala, Elżbieta;
    • Sapa, Jacek;
    • Zajdel, Paweł
    Publication type:
    Article
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    Synthesis of N‐(phenoxyalkyl)‐, N‐{2‐[2‐(phenoxy)ethoxy]ethyl}‐ or N‐(phenoxyacetyl)piperazine Derivatives and Their Activity Within the Central Nervous System.

    Published in:
    ChemistrySelect, 2019, v. 4, n. 32, p. 9381, doi. 10.1002/slct.201902648
    By:
    • Pańczyk, Katarzyna;
    • Pytka, Karolina;
    • Jakubczyk, Magdalena;
    • Rapacz, Anna;
    • Siwek, Agata;
    • Głuch‐Lutwin, Monika;
    • Gryboś, Anna;
    • Słoczyńska, Karolina;
    • Koczurkiewicz, Paulina;
    • Ryszawy, Damian;
    • Pękala, Elżbieta;
    • Budziszewska, Bogusława;
    • Starek‐Świechowicz, Beata;
    • Suraj‐Prażmowska, Joanna;
    • Walczak, Maria;
    • Żesławska, Ewa;
    • Nitek, Wojciech;
    • Bucki, Adam;
    • Kołaczkowski, Marcin;
    • Żelaszczyk, Dorota
    Publication type:
    Article
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    Photodegradation of Bexarotene and Its Implication for Cytotoxicity.

    Published in:
    Pharmaceutics, 2021, v. 13, n. 8, p. 1220, doi. 10.3390/pharmaceutics13081220
    By:
    • Kryczyk-Poprawa, Agata;
    • Zupkó, István;
    • Bérdi, Péter;
    • Żmudzki, Paweł;
    • Piotrowska, Joanna;
    • Pękala, Elżbieta;
    • Berdys, Aleksandra;
    • Muszyńska, Bożena;
    • Opoka, Włodzimierz
    Publication type:
    Article
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