Found: 32
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PS2APP Transgenic Mice, Coexpressing hPS2mut and hAPPswe, Show Age-Related Cognitive Deficits Associated with Discrete Brain Amyloid Deposition and Inflammation.
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- Journal of Neuroscience, 2003, v. 23, n. 26, p. 8989, doi. 10.1523/JNEUROSCI.23-26-08989.2003
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- Article
Hyperphosphorylation and insolubility of a-synuclein in transgenic mouse oligodendrocytes.
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- EMBO Reports, 2002, v. 3, n. 6, p. 583, doi. 10.1093/embo-reports/kvf109
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- Article
Prévenir la progression de la pathologie Tau par immunothérapie passive.
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- Médecine Sciences, 2015, v. 31, n. 2, p. 132, doi. 10.1051/medsci/20153102006
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- Article
Changes in frontocortical interstitial fluid levels of beta-amyloid and Tau protein in transgenic mice models of Alzheimer's disease.
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- Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2014, v. 10, p. P784, doi. 10.1016/j.jalz.2014.05.1515
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- Article
Reduction of phosphorylated tau aggregates in TauPS2APP transgenic mice by passive immunotherapy with an anti-tau/pS422 antibody
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- 2012
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- Abstract
In vivo diffusion tensor imaging and tract-based spatial statistics in three mouse models of Alzheimer's disease
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- 2012
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- Abstract
Cerebral structural changes in different transgenic models of Alzheimer's disease: An MRI study
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- 2012
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- Abstract
1H magnetic resonance spectroscopy longitudinal study in different transgenic mouse models of Alzheimer's disease
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- 2012
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- Abstract
Aminopyrimidines as selective γ-secretase modulators for the potential treatment of AD
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- 2011
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- Abstract
A novel recombinant human amyloid plaque-specific antibody for the treatment of Alzheimer's disease: Molecular properties and preclinical efficacy
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- 2010
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- Abstract
Reduced amyloid and P-tau deposition in TauPS2APP transgenic mice expressing human monoclonal antibodies against Abeta
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- 2010
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- Abstract
Convergence of amyloid-β and tau pathologies on mitochondria
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- 2010
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- Abstract
P2-140: Mitochondrial failure in a transgenic mice model of Alzheimer's disease with plaques and tangles
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- 2008
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- Abstract
Trafficking of Endogenous Immunoglobulins by Endothelial Cells at the Blood-Brain Barrier.
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- Scientific Reports, 2016, p. 25658, doi. 10.1038/srep25658
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- Article
Increase of TREM2 during Aging of an Alzheimer's Disease Mouse Model Is Paralleled by Microglial Activation and Amyloidosis.
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- Frontiers in Aging Neuroscience, 2017, v. 9, p. 1, doi. 10.3389/fnagi.2017.00008
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- Article
Morphologic and Functional Effects of Gamma Secretase Inhibition on Splenic Marginal Zone B Cells.
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- 2012
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- Journal Article
Morphologic and Functional Effects of Gamma Secretase Inhibition on Splenic Marginal Zone B Cells.
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- International Journal of Alzheimer's Disease, 2012, p. 1, doi. 10.1155/2012/289412
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- Article
Expression of Transgenic APP mRNA Is the Key Determinant for Beta-Amyloid Deposition in PS2APP Transgenic Mice.
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- Neurodegenerative Diseases, 2008, v. 6, n. 1/2, p. 29, doi. 10.1159/000170884
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- Article
BACE/APPV717F Double-Transgenic Mice Develop Cerebral Amyloidosis and Inflammation.
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- Neurodegenerative Diseases, 2005, v. 2, n. 6, p. 284, doi. 10.1159/000092314
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- Article
Physiology and Pathophysiology of α-Synuclein: Cell Culture and Transgenic Animal Models Based on a Parkinson's Disease-associated Protein.
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- Annals of the New York Academy of Sciences, 2000, v. 920, n. 1, p. 33, doi. 10.1111/j.1749-6632.2000.tb06902.x
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- Article
Region-specific permeability of the blood–brain barrier upon pericyte loss.
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- Journal of Cerebral Blood Flow & Metabolism, 2017, v. 37, n. 12, p. 3683, doi. 10.1177/0271678X17697340
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- Article
Neuronal uptake of tau/pS422 antibody and reduced progression of tau pathology in a mouse model of Alzheimer's disease.
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- 2014
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- journal article
Neuronal uptake of tau/pS422 antibody and reduced progression of tau pathology in a mouse model of Alzheimer‘s disease.
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- Brain: A Journal of Neurology, 2014, v. 137, n. 10, p. 2834, doi. 10.1093/brain/awu213
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- Article
Pharmacological and genetic evidence indicates that combined inhibition of NR2A and NR2B subunit containing NMDA receptors is required to disrupt prepulse inhibition.
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- Psychopharmacology, 2004, v. 175, n. 1, p. 99, doi. 10.1007/s00213-004-1785-y
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- Article
Early and Longitudinal Microglial Activation but Not Amyloid Accumulation Predicts Cognitive Outcome in PS2APP Mice.
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- Journal of Nuclear Medicine, 2019, v. 60, n. 4, p. 548, doi. 10.2967/jnumed.118.217703
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- Article
Microglial response to increasing amyloid load saturates with aging: a longitudinal dual tracer in vivo μPET-study.
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- 2018
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- Publication type:
- journal article
The dynamics of Aβ distribution after γ-secretase inhibitor treatment, as determined by experimental and modelling approaches in a wild type rat.
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- Journal of Pharmacokinetics & Pharmacodynamics, 2012, v. 39, n. 3, p. 227, doi. 10.1007/s10928-012-9246-4
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- Article
Decreasing the Expression of GABA<sub>A</sub> α5 Subunit-Containing Receptors Partially Improves Cognitive, Electrophysiological, and Morphological Hippocampal Defects in the Ts65Dn Model of Down Syndrome.
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- Molecular Neurobiology, 2018, v. 55, n. 6, p. 4745, doi. 10.1007/s12035-017-0675-3
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- Article
Interleukin-12 is required for interferon-γ production and lethality in lipopolysaccharide-induced shock in mice.
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- European Journal of Immunology, 1995, v. 25, n. 3, p. 672, doi. 10.1002/eji.1830250307
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- Article
Experimental therapy of systemic lupus erythematosus: the treatment of NZB/W mice with mouse soluble interferon-γ receptor inhibits the onset of glomerulonephritis.
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- European Journal of Immunology, 1995, v. 25, n. 1, p. 6, doi. 10.1002/eji.1830250103
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- Article
Distribution of interferon-γ receptor in human tissues.
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- European Journal of Immunology, 1992, v. 22, n. 9, p. 2403, doi. 10.1002/eji.1830220933
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- Article
Combined Treatment with a BACE Inhibitor and Anti-Aβ Antibody Gantenerumab Enhances Amyloid Reduction in APP<sub>London</sub> Mice.
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- Journal of Neuroscience, 2014, v. 34, n. 35, p. 11621, doi. 10.1523/JNEUROSCI.1405-14.2014
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- Publication type:
- Article