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A quantitative neuropathological assessment of translocator protein expression in multiple sclerosis.
Published in:
2019
By:
- Nutma, Erik;
- Stephenson, Jodie A;
- Gorter, Rianne P;
- Bruin, Joy de;
- Boucherie, Deirdre M;
- Donat, Cornelius K;
- Breur, Marjolein;
- van der Valk, Paul;
- Matthews, Paul M;
- Owen, David R;
- Amor, Sandra;
- de Bruin, Joy
Publication type:
journal article
Minocycline reduces chronic microglial activation after brain trauma but increases neurodegeneration.
Published in:
2018
By:
- Scott, Gregory;
- Zetterberg, Henrik;
- Jolly, Amy;
- Cole, James H.;
- De Simoni, Sara;
- Jenkins, Peter O.;
- Feeney, Claire;
- Owen, David R.;
- Lingford-Hughes, Anne;
- Howes, Oliver;
- Patel, Maneesh C.;
- Goldstone, Anthony P.;
- Gunn, Roger N.;
- Blennow, Kaj;
- Matthews, Paul M.;
- Sharp, David J.
Publication type:
journal article
Roles of microglia in brain development, tissue maintenance and repair.
Published in:
Brain: A Journal of Neurology, 2015, v. 138, n. 5, p. 1138, doi. 10.1093/brain/awv066
By:
- Michell-Robinson, Mackenzie A.;
- Touil, Hanane;
- Healy, Luke M.;
- Owen, David R.;
- Durafourt, Bryce A.;
- Bar-Or, Amit;
- Antel, Jack P.;
- Moore, Craig S.
Publication type:
Article
Signalling pathways associated with impaired angiogenesis in Alzheimer's Disease.
Published in:
Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2023, v. 19, p. 1, doi. 10.1002/alz.080123
By:
- Tsartsalis, Stergios;
- Sleven, Hannah;
- Fancy, Nurun N;
- Wessely, Frank;
- Willumsen, Nanet;
- Michal, Rokicki;
- Chau, Vicky;
- Ifie, Eseoghene;
- Khozoie, Combiz;
- Ansorge, Olaf;
- Owen, David R;
- Webber, Caleb;
- Jackson, Johanna;
- Cader, Zameel;
- Matthews, Paul M
Publication type:
Article
Signalling pathways associated with impaired angiogenesis in Alzheimer's Disease.
Published in:
Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2023, v. 19, p. 1, doi. 10.1002/alz.080123
By:
- Tsartsalis, Stergios;
- Sleven, Hannah;
- Fancy, Nurun N;
- Wessely, Frank;
- Willumsen, Nanet;
- Michal, Rokicki;
- Chau, Vicky;
- Ifie, Eseoghene;
- Khozoie, Combiz;
- Ansorge, Olaf;
- Owen, David R;
- Webber, Caleb;
- Jackson, Johanna;
- Cader, Zameel;
- Matthews, Paul M
Publication type:
Article
Mood and Cycling Performance in Response to Three Weeks of High-Intensity, Short-Duration Overtraining, and a Two-Week Taper.
Published in:
Sport Psychologist, 1999, v. 13, n. 4, p. 444, doi. 10.1123/tsp.13.4.444
By:
- Berger, Bonnie G.;
- Motl, Robert W.;
- Butki, Brian D.;
- Martin, David T.;
- Wilkinson, John G.;
- Owen, David R.
Publication type:
Article
TSPO mutations in rats and a human polymorphism impair the rate of steroid synthesis.
Published in:
Biochemical Journal, 2017, v. 474, n. 23, p. 3985, doi. 10.1042/BCJ20170648
By:
- Owen, David R.;
- Jinjiang Fan;
- Campioli, Enrico;
- Venugopal, Sathvika;
- Midzak, Andrew;
- Daly, Edward;
- Harlay, Aline;
- Issop, Leeyah;
- Libri, Vincenzo;
- Kalogiannopoulou, Dimitra;
- Oliver, Eduardo;
- Gallego-Colon, Enrique;
- Colasanti, Alessandro;
- Huson, Les;
- Rabiner, Eugenii A.;
- Suppiah, Puvan;
- Essagian, Charles;
- Matthews, Paul M.;
- Papadopoulos, Vassilios
Publication type:
Article
Balance laws and a dissipation inequality for general constituents undergoing disarrangements and mixing.
Published in:
ZAMM -- Journal of Applied Mathematics & Mechanics / Zeitschrift für Angewandte Mathematik und Mechanik, 2008, v. 88, n. 5, p. 365, doi. 10.1002/zamm.200800003
By:
- Owen, David R.
Publication type:
Article
"Feeling Good" After Exercise During a Weight Loss Program: Subjective Well-Being in Support of a Hedonic Paradigm.
Published in:
Perceptual & Motor Skills, 2023, v. 130, n. 1, p. 434, doi. 10.1177/00315125221130444
By:
- Berger, Bonnie G.;
- Darby, Lynn A.;
- Owen, David R.;
- Carels, Robert A.
Publication type:
Article
Polynomial Approximations to the Cumulative Fisher Distribution.
Published in:
Educational & Psychological Measurement, 1972, v. 32, n. 1, p. 97, doi. 10.1177/001316447203200109
By:
- Owen, David R.
Publication type:
Article
Review: Towards molecular imaging of multiple sclerosis.
Published in:
Multiple Sclerosis Journal, 2011, v. 17, n. 3, p. 262, doi. 10.1177/1352458510390070
By:
- Owen, David R. J.;
- Piccini, Paola;
- Matthews, Paul M.
Publication type:
Article
Athletic Identity, Career Maturity, and Subjective Well-being of NCAA Division I and III Football Players.
Published in:
Journal of Sport Behavior, 2021, v. 44, n. 3, p. 321
By:
- Mathews, Alyssa. M.;
- Berger, Bonnie G.;
- Darby, Lynn A.;
- Owen, David R.;
- Tobar, David A.
Publication type:
Article
Mood Alteration After 15 Minutes of Preferred Intensity Exercise: Examining Heart Rate, Perceived Exertion, and Enjoyment.
Published in:
Journal of Sport Behavior, 2016, v. 39, n. 1, p. 3
By:
- Berger, Bonnie G.;
- Darby, Lynn A.;
- Yu Zhang;
- Owen, David R.;
- Tobar, David A.
Publication type:
Article
National secular trends in intelligence and education: a twenty-year cross-sectional study.
Published in:
Nature, 1987, v. 325, n. 6100, p. 119, doi. 10.1038/325119a0
By:
- Teasdale, T. W.;
- Owen, David R.
Publication type:
Article
Heredity and familial environment in intelligence and educational level-a sibling study.
Published in:
Nature, 1984, v. 309, n. 5969, p. 620, doi. 10.1038/309620a0
By:
- Teasdale, T. W.;
- Owen, David R.
Publication type:
Article
Inclusive and equitable language for skin colour in the British Journal of Dermatology: acknowledging our past and laying the foundations to move forward.
Published in:
British Journal of Dermatology, 2024, v. 190, n. 5, p. 605, doi. 10.1093/bjd/ljae064
By:
- Oyesiku, Linda;
- Dlova, Ncoza;
- Ahmed, Shehnaz;
- Owen, David R;
- Ingram, John R;
- Freeman, Esther;
- Jablonski, Nina G
Publication type:
Article
Corrigendum: Phagocytosis in the Brain: Homeostasis and Disease.
Published in:
2019
By:
- Galloway, Dylan A.;
- Phillips, Alexandra E. M.;
- Owen, David R. J.;
- Moore, Craig S.
Publication type:
Correction Notice
Human pharmacokinetics of XBD173 and etifoxine distinguish their potential for pharmacodynamic effects mediated by translocator protein.
Published in:
British Journal of Clinical Pharmacology, 2022, v. 88, n. 9, p. 4230, doi. 10.1111/bcp.15392
By:
- Owen, David R.;
- Phillips, Alexandra;
- O'Connor, Desmond;
- Grey, Gabrielle;
- Aimola, Lina;
- Nicholas, Richard;
- Matthews, Paul M.
Publication type:
Article
11C-DPA-713 has much greater specific binding to translocator protein 18 kDa (TSPO) in human brain than 11C-(R)-PK11195.
Published in:
Journal of Cerebral Blood Flow & Metabolism, 2018, v. 38, n. 3, p. 393, doi. 10.1177/0271678X17699223
By:
- Kobayashi, Masato;
- Jiang, Teresa;
- Telu, Sanjay;
- Zoghbi, Sami S.;
- Gunn, Roger N.;
- Rabiner, Eugenii A.;
- Owen, David R.;
- Guo, Qi;
- Pike, Victor W.;
- Innis, Robert B.;
- Fujita, Masahiro
Publication type:
Article
Pro-inflammatory activation of primary microglia and macrophages increases 18 kDa translocator protein expression in rodents but not humans.
Published in:
Journal of Cerebral Blood Flow & Metabolism, 2017, v. 37, n. 8, p. 2679, doi. 10.1177/0271678X17710182
By:
- Owen, David R.;
- Narayan, Nehal;
- Wells, Lisa;
- Healy, Luke;
- Smyth, Erica;
- Rabiner, Eugenii A.;
- Galloway, Dylan;
- Williams, John B.;
- Lehr, Joshua;
- Mandhair, Harpreet;
- Peferoen, Laura A. N.;
- Taylor, Peter C.;
- Amor, Sandra;
- Antel, Jack P.;
- Matthews, Paul M.
Publication type:
Article
A graphical method to compare the in vivo binding potential of PET radioligands in the absence of a reference region: application to [11C]PBR28 and [18F]PBR111 for TSPO imaging.
Published in:
Journal of Cerebral Blood Flow & Metabolism, 2014, v. 34, n. 7, p. 1162, doi. 10.1038/jcbfm.2014.65
By:
- Guo, Qi;
- Owen, David R;
- Rabiner, Eugenii A;
- Turkheimer, Federico E;
- Gunn, Roger N
Publication type:
Article
Determination of [11C]PBR28 binding potential in vivo: a first human TSPO blocking study.
Published in:
Journal of Cerebral Blood Flow & Metabolism, 2014, v. 34, n. 7, p. 1256, doi. 10.1038/jcbfm.2014.84
By:
- Owen, David R;
- Guo, Qi;
- Kalk, Nicola J;
- Colasanti, Alessandro;
- Kalogiannopoulou, Dimitra;
- Dimber, Rahul;
- Lewis, Yvonne L;
- Libri, Vincenzo;
- Barletta, Julien;
- Ramada-Magalhaes, Joaquim;
- Kamalakaran, Aruloly;
- Nutt, David J;
- Passchier, Jan;
- Matthews, Paul M;
- Gunn, Roger N;
- Rabiner, Eugenii A
Publication type:
Article
Determination of [11C]PBR28 binding potential in vivo: a first human TSPO blocking study.
Published in:
Journal of Cerebral Blood Flow & Metabolism, 2014, v. 34, n. 6, p. 989, doi. 10.1038/jcbfm.2014.46
By:
- Owen, David R;
- Guo, Qi;
- Kalk, Nicola J;
- Colasanti, Alessandro;
- Kalogiannopoulou, Dimitra;
- Dimber, Rahul;
- Lewis, Yvonne L;
- Libri, Vincenzo;
- Barletta, Julien;
- Ramada-Magalhaes, Joaquim;
- Kamalakaran, Aruloly;
- Nutt, David J;
- Passchier, Jan;
- Matthews, Paul M;
- Gunn, Roger N;
- Rabiner, Eugenii A
Publication type:
Article
An 18-kDa Translocator Protein (TSPO) polymorphism explains differences in binding affinity of the PET radioligand PBR28.
Published in:
Journal of Cerebral Blood Flow & Metabolism, 2012, v. 32, n. 1, p. 1, doi. 10.1038/jcbfm.2011.147
By:
- Owen, David R;
- Yeo, Astrid J;
- Gunn, Roger N;
- Song, Kijoung;
- Wadsworth, Graham;
- Lewis, Andrew;
- Rhodes, Chris;
- Pulford, David J;
- Bennacef, Idriss;
- Parker, Christine A;
- StJean, Pamela L;
- Cardon, Lon R;
- Mooser, Vincent E;
- Matthews, Paul M;
- Rabiner, Eugenii A;
- Rubio, Justin P
Publication type:
Article
Two binding sites for [3H]PBR28 in human brain: implications for TSPO PET imaging of neuroinflammation.
Published in:
Journal of Cerebral Blood Flow & Metabolism, 2010, v. 30, n. 9, p. 1608, doi. 10.1038/jcbfm.2010.63
By:
- Owen, David R.;
- Howell, Owain W.;
- Tang, Sac-Pham;
- Wells, Lisa A.;
- Bennacef, Idriss;
- Bergstrom, Mats;
- Gunn, Roger N.;
- Rabiner, Eugenii A.;
- Wilkins, Martin R.;
- Reynolds, Richard;
- Matthews, Paul M.;
- Parker, Christine A.
Publication type:
Article
Using team-based revision to prepare medical students for the prescribing safety assessment.
Published in:
Advances in Medical Education & Practice, 2019, v. 10, p. 501, doi. 10.2147/AMEP.S204435
By:
- Field, Samantha M;
- Burstow, Nicholas J;
- Owen, David R;
- Sam, Amir H
Publication type:
Article
Advances in positron emission tomography for the imaging of rheumatoid arthritis.
Published in:
Rheumatology, 2017, v. 56, n. 11, p. 1837, doi. 10.1093/rheumatology/kew484
By:
- Narayan, Nehal;
- Owen, David R.;
- Taylor, Peter C.
Publication type:
Article
Translocator Protein as an Imaging Marker of Macrophage and Stromal Activation in Rheumatoid Arthritis Pannus.
Published in:
Journal of Nuclear Medicine, 2018, v. 59, n. 7, p. 1125, doi. 10.2967/jnumed.117.202200
By:
- Narayan, Nehal;
- Owen, David R.;
- Mandhair, Harpreet;
- Smyth, Erica;
- Carlucci, Francesco;
- Saleem, Azeem;
- Gunn, Roger N.;
- Rabiner, Eugenii A.;
- Wells, Lisa;
- Dakin, Stephanie G.;
- Sabokbar, Afsie;
- Taylor, Peter C.
Publication type:
Article
In Vivo Assessment of Brain White Matter Inflammation in Multiple Sclerosis with 18F-PBR111 PET.
Published in:
Journal of Nuclear Medicine, 2014, v. 55, n. 7, p. 1112, doi. 10.2967/jnumed.113.135129
By:
- Colasanti, Alessandro;
- Qi Guo;
- Muhlert, Nils;
- Giannetti, Paolo;
- Onega, Mayca;
- Newbould, Rexford D.;
- Ciccarelli, Olga;
- Rison, Stuart;
- Thomas, Charlotte;
- Nicholas, Richard;
- Muraro, Paolo A.;
- Malik, Omar;
- Owen, David R.;
- Piccini, Paola;
- Gunn, Roger N.;
- Rabiner, Eugenii A.;
- Matthews, Paul M.
Publication type:
Article
Quantification of the Specific Translocator Protein Signal of 18F-PBR111 in Healthy Humans: A Genetic Polymorphism Effect on In Vivo Binding.
Published in:
Journal of Nuclear Medicine, 2013, v. 54, n. 11, p. 1915, doi. 10.2967/jnumed.113.121020
By:
- Qi Guo;
- Colasanti, Alessandro;
- Owen, David R.;
- Onega, Mayca;
- Kamalakaran, Aruloly;
- Bennacef, Idriss;
- Matthews, Paul M.;
- Rabiner, Eugenii A.;
- Turkheimer, Federico E.;
- Gunn, Roger N.
Publication type:
Article
Mixed-Affinity Binding in Humans with 18-kDa Translocator Protein Ligands.
Published in:
Journal of Nuclear Medicine, 2011, v. 52, n. 1, p. 24, doi. 10.2967/jnumed.110.079459
By:
- Owen, David R. J.;
- Gunn, Roger N.;
- Rabiner, Eugenii A.;
- Bennacef, Idriss;
- Fujita, Masahiro;
- Kreisl, William C.;
- Innis, Robert B.;
- Pike, Victor W.;
- Reynolds, Richard;
- Matthews, Paul M.;
- Parker, Christine A.
Publication type:
Article
Upscaling and spatial localization of non-local energies with applications to crystal plasticity.
Published in:
Mathematics & Mechanics of Solids, 2021, v. 26, n. 7, p. 963, doi. 10.1177/1081286520973245
By:
- Matias, José;
- Morandotti, Marco;
- Owen, David R.;
- Zappale, Elvira
Publication type:
Article
Submacroscopically Stable Equilibria of Elastic Bodies Undergoing Disarrangements and Dissipation.
Published in:
Mathematics & Mechanics of Solids, 2010, v. 15, n. 6, p. 611, doi. 10.1177/1081286509106101
By:
- DESERI, LUCA;
- OWEN, DAVID R.
Publication type:
Article
Energetics of Two-level Shears and Hardening of Single Crystals.
Published in:
Mathematics & Mechanics of Solids, 2002, v. 7, n. 2, p. 113, doi. 10.1177/1081286502007002225
By:
- Deseri, Luca;
- Owen, David R.
Publication type:
Article
A PET-CT study on neuroinflammation in Huntington's disease patients participating in a randomized trial with laquinimod.
Published in:
Brain Communications, 2023, v. 5, n. 2, p. 1, doi. 10.1093/braincomms/fcad084
By:
- Roussakis, Andreas-Antonios;
- Gennaro, Marta;
- Gordon, Mark Forrest;
- Reilmann, Ralf;
- Borowsky, Beth;
- Rynkowski, Gail;
- Lao-Kaim, Nicholas P.;
- Papoutsou, Zoe;
- Savola, Juha-Matti;
- Hayden, Michael R.;
- Owen, David R.;
- Kalk, Nicola;
- Lingford-Hughes, Anne;
- Gunn, Roger N.;
- Searle, Graham;
- Tabrizi, Sarah J.;
- Piccini, Paola
Publication type:
Article
Diverse human astrocyte and microglial transcriptional responses to Alzheimer's pathology.
Published in:
Acta Neuropathologica, 2022, v. 143, n. 1, p. 75, doi. 10.1007/s00401-021-02372-6
By:
- Smith, Amy M.;
- Davey, Karen;
- Tsartsalis, Stergios;
- Khozoie, Combiz;
- Fancy, Nurun;
- Tang, See Swee;
- Liaptsi, Eirini;
- Weinert, Maria;
- McGarry, Aisling;
- Muirhead, Robert C. J.;
- Gentleman, Steve;
- Owen, David R.;
- Matthews, Paul M.
Publication type:
Article
Cross-platform transcriptional profiling identifies common and distinct molecular pathologies in Lewy body diseases.
Published in:
Acta Neuropathologica, 2021, v. 142, n. 3, p. 449, doi. 10.1007/s00401-021-02343-x
By:
- Feleke, Rahel;
- Reynolds, Regina H.;
- Smith, Amy M.;
- Tilley, Bension;
- Taliun, Sarah A. Gagliano;
- Hardy, John;
- Matthews, Paul M.;
- Gentleman, Steve;
- Owen, David R.;
- Johnson, Michael R.;
- Srivastava, Prashant K.;
- Ryten, Mina
Publication type:
Article
Activated microglia do not increase 18 kDa translocator protein (TSPO) expression in the multiple sclerosis brain.
Published in:
Glia, 2021, v. 69, n. 10, p. 2447, doi. 10.1002/glia.24052
By:
- Nutma, Erik;
- Gebro, Emeline;
- Marzin, Manuel C.;
- van der Valk, Paul;
- Matthews, Paul M.;
- Owen, David R.;
- Amor, Sandra
Publication type:
Article
New Long-Acting Basal Insulins: Does Benefit Outweigh Cost?
Published in:
2016
By:
- Standl, Eberhard;
- Owen, David R.
Publication type:
journal article
Decaffeinated Coffee and Glucose Metabolism in Young Men.
Published in:
Diabetes Care, 2010, v. 33, n. 2, p. 278, doi. 10.2337/dc09-1539
By:
- Greenberg, James A.;
- Owen, David R.;
- Geliebter, Allan
Publication type:
Article
Preclinical evaluation of (S)-[18F]GE387, a novel 18-kDa translocator protein (TSPO) PET radioligand with low binding sensitivity to human polymorphism rs6971.
Published in:
European Journal of Nuclear Medicine & Molecular Imaging, 2021, v. 49, n. 1, p. 125, doi. 10.1007/s00259-021-05495-w
By:
- Ramakrishnan, Nisha K.;
- Hird, Matthew;
- Thompson, Stephen;
- Williamson, David J.;
- Qiao, Luxi;
- Owen, David R.;
- Brooks, Allen F.;
- Scott, Peter J. H.;
- Bacallado, Sergio;
- O'Brien, John T.;
- Aigbirhio, Franklin I.
Publication type:
Article
Cellular sources of TSPO expression in healthy and diseased brain.
Published in:
European Journal of Nuclear Medicine & Molecular Imaging, 2021, v. 49, n. 1, p. 146, doi. 10.1007/s00259-020-05166-2
By:
- Nutma, Erik;
- Ceyzériat, Kelly;
- Amor, Sandra;
- Tsartsalis, Stergios;
- Millet, Philippe;
- Owen, David R.;
- Papadopoulos, Vassilios;
- Tournier, Benjamin B.
Publication type:
Article
Specific and non-specific binding of a tracer for the translocator-specific protein in schizophrenia: an [11C]-PBR28 blocking study.
Published in:
European Journal of Nuclear Medicine & Molecular Imaging, 2021, v. 48, n. 11, p. 3530, doi. 10.1007/s00259-021-05327-x
By:
- Marques, Tiago Reis;
- Veronese, Mattia;
- Owen, David R.;
- Rabiner, Eugenii A.;
- Searle, Graham E.;
- Howes, Oliver D.
Publication type:
Article
Phenibut (4-amino-3-phenyl-butyric acid): Availability, prevalence of use, desired effects and acute toxicity.
Published in:
2016
By:
- Owen, David R.;
- Wood, David M.;
- Archer, John R. H.;
- Dargan, Paul I.
Publication type:
journal article
Stratified medicine in psychiatry: a worrying example or new opportunity in the treatment of anxiety?
Published in:
Journal of Psychopharmacology, 2013, v. 27, n. 2, p. 119, doi. 10.1177/0269881112443746
By:
- Owen, David R;
- Rupprecht, Rainer;
- Nutt, David J
Publication type:
Article

Found: 45