Works by Ouzzine, Mohamed

Results: 19

Chondroitin sulfate N-acetylgalactosaminyltransferase-1 (CSGalNAcT-1) involved in chondroitin sulfate initiation: Impact of sulfation on activity and specificity.

Published in:

Glycobiology, 2012, v. 22, n. 4, p. 561, doi. 10.1093/glycob/cwr172

By:

Gulberti, Sandrine;
Jacquinet, Jean-Claude;
Chabel, Matthieu;
Ramalanjaona, Nick;
Magdalou, Jacques;
Netter, Patrick;
Coughtrie, Michael W H;
Ouzzine, Mohamed;
Fournel-Gigleux, Sylvie

Publication type:

Article

Molecular basis for acceptor substrate specificity of the human {beta}1,3-glucuronosyltransferases GlcAT-I and GlcAT-P involved in glycosaminoglycan and HNK-1 carbohydrate epitope biosynthesis, respectively.

Published in:

Glycobiology, 2007, v. 17, n. 8, p. 857, doi. 10.1093/glycob/cwm055

By:

Magali Fondeur-Gelinotte;
Virginie Lattard;
Sandrine Gulberti;
Rafael Oriol;
Guillermo Mulliert;
Michael WH Coughtrie;
Jacques Magdalou;
Patrick Netter;
Mohamed Ouzzine;
Sylvie Fournel-Gigleux

Publication type:

Article

Glycosyltransferases and Glycosaminoglycans in Bleomycin and Transforming Growth Factor-β1-Induced Pulmonary Fibrosis.

Published in:

American Journal of Respiratory Cell & Molecular Biology, 2014, v. 50, n. 3, p. 583, doi. 10.1165/rcmb.2012-0226OC

By:

Venkatesan, Narayanan;
Tsuchiya, Kimitake;
Kolb, Martin;
Farkas, Laszlo;
Bourhim, Mustapha;
Ouzzine, Mohamed;
Ludwig, Mara S.

Publication type:

Article

FAM20B Gain-of-Function Blocks the Synthesis of Glycosaminoglycan Chains of Proteoglycans and Inhibits Proliferation and Migration of Glioblastoma Cells.

Published in:

Cells (2073-4409), 2025, v. 14, n. 10, p. 712, doi. 10.3390/cells14100712

By:

Barré, Lydia;
Shaukat, Irfan;
Ouzzine, Mohamed

Publication type:

Article

Substrate specificity of the human UDP-glucuronosyltransferase UGT2B4 and UGT2B7.

Published in:

FEBS Journal, 2007, v. 274, n. 5, p. 1256, doi. 10.1111/j.1742-4658.2007.05670.x

By:

Barre, Lydia;
Fournel-Gigleux, Sylvie;
Finel, Moshe;
Netter, Patrick;
Magdalou, Jacques;
Ouzzine, Mohamed

Publication type:

Article

The stop transfer sequence of the human UDP-glucuronosyltransferase 1A determines localization to the endoplasmic reticulum by both static retention and retrieval mechanisms.

Published in:

FEBS Journal, 2005, v. 272, n. 4, p. 1063, doi. 10.1111/j.1742-4658.2005.04548.x

By:

Barré, Lydia;
Magdalou, Jacques;
Netter, Patrick;
Fournel-Gigleux, Sylvie;
Ouzzine, Mohamed

Publication type:

Article

Targeting of Proteoglycan Synthesis Pathway: A New Strategy to Counteract Excessive Matrix Proteoglycan Deposition and Transforming Growth Factor-β1-Induced Fibrotic Phenotype in Lung Fibroblasts.

Published in:

PLoS ONE, 2016, v. 11, n. 1, p. 1, doi. 10.1371/journal.pone.0146499

By:

Shaukat, Irfan;
Barré, Lydia;
Venkatesan, Narayanan;
Li, Dong;
Jaquinet, Jean-Claude;
Fournel-Gigleux, Sylvie;
Ouzzine, Mohamed

Publication type:

Article

Phylogenetic and mutational analyses reveal key residues for UDP-glucuronic acid binding and activity of β1,3-glucuronosyltransferase I (GlcAT-I).

Published in:

Protein Science: A Publication of the Protein Society, 2006, v. 15, n. 7, p. 1667, doi. 10.1110/ps.062089106

By:

Fondeur-Gelinotte, Magali;
Lattard, Virginie;
Oriol, Rafael;
Mollicone, Rosella;
Jacquinet, Jean-Claude;
Mulliert, Guillermo;
Gulberti, Sandrine;
Netter, Patrick;
Magdalou, Jacques;
Ouzzine, Mohamed;
Fournel-Gigleux, Sylvie

Publication type:

Article

Molecular characterization of β1,4-galactosyltransferase 7 genetic mutations linked to the progeroid form of Ehlers–Danlos syndrome (EDS)

Published in:

FEBS Letters, 2010, v. 584, n. 18, p. 3962, doi. 10.1016/j.febslet.2010.08.001

By:

Bui, Catherine;
Talhaoui, Ibtissam;
Chabel, Matthieu;
Mulliert, Guillermo;
Coughtrie, Michael W.H.;
Ouzzine, Mohamed;
Fournel-Gigleux, Sylvie

Publication type:

Article

Involvement of thapsigargin- and cyclopiazonic acid-sensitive pumps in the rescue of TMEM165-associated glycosylation defects by Mn<sup>2+</sup>.

Published in:

FASEB Journal, 2019, v. 33, n. 2, p. 2669, doi. 10.1096/fj.201800387R

By:

Houdou, Marine;
Lebredonchel, Elodie;
Garat, Anne;
Duvet, Sandrine;
Legrand, Dominique;
Decool, Valérie;
Klein, André;
Ouzzine, Mohamed;
Gasnier, Bruno;
Potelle, Sven;
Foulquier, François

Publication type:

Article

Epigenetics: methylation-associated repression of heparan sulfate 3-O-sulfotransferase gene expression contributes to the invasive phenotype of H-EMC-SS chondrosarcoma cells.

Published in:

FASEB Journal, 2010, v. 24, n. 2, p. 436, doi. 10.1096/fj.09-136291

By:

Bui, Catherine;
Ouzzine, Mohamed;
Talhaoui, Ibtissam;
Sharp, Sheila;
Prydz, Kristian;
Coughtrie, Michael W. H.;
Fournel-Gigleux, Sylvie

Publication type:

Article

Modulation of xylosyltransferase I expression provides a mechanism regulating glycosaminoglycan chain synthesis during cartilage destruction and repair.

Published in:

FASEB Journal, 2009, v. 23, n. 3, p. 813, doi. 10.1096/fj.08-118166

By:

Venkatesan, Narayanan;
Barré, Lydia;
Magdalou, Jacques;
Mainard, Didier;
Netter, Patrick;
Fournei-Gigleux, Sylvie;
Ouzzine, Mohamed

Publication type:

Article

Evidence of calcium-dependent pathway in the regulation of human β1,3-glucuronosyltransferase-1 (GlcAT-I) gene expression: a key enzyme in proteoglycan synthesis.

Published in:

FASEB Journal, 2006, v. 20, n. 10, p. 1692, doi. 10.1096/fj.05-5073fje

By:

Barré, Lydia;
Venkatesan, Narayanan;
Magdalou, Jacques;
Netter, Patrick;
Fournel-Gigleux, Sylvie;
Ouzzine, Mohamed

Publication type:

Article

Xylosyltransferase-I Regulates Glycosaminoglycan Synthesis during the Pathogenic Process of Human Osteoarthritis.

Published in:

PLoS ONE, 2012, v. 7, n. 3, p. 1, doi. 10.1371/journal.pone.0034020

By:

Venkatesan, Narayanan;
Barré, Lydia;
Bourhim, Mustapha;
Magdalou, Jacques;
Mainard, Didier;
Netter, Patrick;
Fournel-Gigleux, Sylvie;
Ouzzine, Mohamed

Publication type:

Article

Insights on membrane topology and structure/function of UDP-glucuronosyltransferases.

Published in:

Drug Metabolism Reviews, 2010, v. 42, n. 1, p. 154, doi. 10.3109/03602530903209270

By:

Magdalou, Jacques;
Fournel-Gigleux, Sylvie;
Ouzzine, Mohamed

Publication type:

Article

The Human UDP-Glucuronosyltransferases: Structural Aspects and Drug Glucuronidation.

Published in:

Drug Metabolism Reviews, 2003, v. 35, n. 4, p. 287, doi. 10.1081/DMR-120026397

By:

Ouzzine, Mohamed;
Barré, Lydia;
Netter, Patrick;
Magdalou, Jacques;
Fournel-Gigleux, Sylvie

Publication type:

Article

The UDP-glucuronosyltransferases of the blood-brain barrier: their role in drug metabolism and detoxication.

Published in:

Frontiers in Cellular Neuroscience, 2014, v. 8, p. 1, doi. 10.3389/fncel.2014.00349

By:

Ouzzine, Mohamed;
Gulberti, Sandrine;
Ramalanjaona, Nick;
Magdalou, Jacques;
Fournel-Gigleux, Sylvie

Publication type:

Article

Xylosyltransferase I mediates the synthesis of proteoglycans with long glycosaminoglycan chains and controls chondrocyte hypertrophy and collagen fibers organization of in the growth plate.

Published in:

Cell Death & Disease, 2023, v. 14, n. 6, p. 1, doi. 10.1038/s41419-023-05875-0

By:

Taieb, Mahdia;
Ghannoum, Dima;
Barré, Lydia;
Ouzzine, Mohamed

Publication type:

Article

TMEM165 a new player in proteoglycan synthesis: loss of TMEM165 impairs elongation of chondroitin- and heparan-sulfate glycosaminoglycan chains of proteoglycans and triggers early chondrocyte differentiation and hypertrophy.

Published in:

Cell Death & Disease, 2022, v. 13, n. 1, p. 1, doi. 10.1038/s41419-021-04458-1

By:

Khan, Sajida;
Sbeity, Malak;
Foulquier, François;
Barré, Lydia;
Ouzzine, Mohamed

Publication type:

Article