Works by Ouyang, John

Results: 31

Systems level identification of a matrisome-associated macrophage polarisation state in multi-organ fibrosis.

Published in:

eLife, 2023, p. 1, doi. 10.7554/eLife.85530

By:

Ouyang, John F.;
Mishra, Kunal;
Yi Xie;
Park, Harry;
Huang, Kevin Y.;
Petretto, Enrico;
Behmoaras, Jacques

Publication type:

Article

Short-term Clinical Effects of Tolvaptan, an Oral Vasopressin Antagonist, in Patients Hospitalized for Heart Failure.

Published in:

JAMA: Journal of the American Medical Association, 2007, v. 297, n. 12, p. 1332, doi. 10.1001/jama.297.12.1332

By:

Gheorghiade, Mihai;
Konstam, Marvin A.;
Bennett Jr., John C.;
Grinfeld, Liliana;
Maggioni, Aldo P.;
Swedberg, Karl;
Udelson, James E.;
Zannad, Faiez;
Cook, Thomas;
Ouyang, John;
Zimmer, Christopher;
Orlandi, Cesare

Publication type:

Article

Effects of Oral Tolvaptan in Patients Hospitalized for Worsening Heart Failure.

Published in:

JAMA: Journal of the American Medical Association, 2007, v. 297, n. 12, p. 1319, doi. 10.1001/jama.297.12.1319

By:

Konstam, Marvin A.;
Gheorghiade, Mihai;
Burnett, Jr., John C.;
Grinfeld, Liliana;
Maggioni, Aldo P.;
Swedberg, Karl;
Udelson, James E.;
Zannad, Faiez;
Cook, Thomas;
Ouyang, John;
Zimmer, Christopher;
Orlandi, Cesare

Publication type:

Article

Effects of Tolvaptan, a Vasopressin Antagonist, in Patients Hospitalized With Worsening Heart Failure: A Randomized Controlled Trial.

Published in:

JAMA: Journal of the American Medical Association, 2004, v. 291, n. 16, p. 1963, doi. 10.1001/jama.291.16.1963

By:

Gheorghiade, Mihai;
Gattis, Wendy A.;
O'Connor, Christopher M.;
Adams, Jr, Kirkwood F.;
Elkayam, Uri;
Barbagelata, Alejandro;
Ghali, Jalal K.;
Benza, Raymond L.;
McGrew, Frank A.;
Klapholz, Marc;
Ouyang, John;
Orlandi, Cesare

Publication type:

Article

FP046 A PHASE 2 DOSE-RANGING STUDY COMPARING PHARMACOKINETICS (PK), PHARMACODYNAMICS (PD), AND TOLERABILITY OF MODIFIED RELEASE (MR) VS IMMEDIATE RELEASE (IR) TOLVAPTAN (TLV) IN AUTOSOMAL DOMINANT POLYCYSTIC KIDNEY DISEASE (ADPKD) PATIENTS (PT).

Published in:

Nephrology Dialysis Transplantation, 2019, v. 34, p. N.PAG, doi. 10.1093/ndt/gfz106.FP046

By:

Perrone, Ronald;
Chapman, Arlene;
Oberdhan, Dorothee;
Czerwiec, Frank S;
Sergeyeva, Olga;
Ouyang, John;
Shoaf, Susan

Publication type:

Article

FP045 NOCTURNE: A PHASE 2, RANDOMIZED, PLACEBO-CONTROLLED TRIAL TO COMPARE TOLVAPTAN (TLV) MODIFIED-RELEASE (MR) AND IMMEDIATE-RELEASE (IR) FORMULATIONS IN AUTOSOMAL DOMINANT POLYCYSTIC KIDNEY DISEASE (ADPKD) PATIENTS (PT).

Published in:

Nephrology Dialysis Transplantation, 2019, v. 34, p. N.PAG, doi. 10.1093/ndt/gfz106.FP045

By:

Perrone, Ronald;
Chapman, Arlene;
Oberdhan, Dorothee;
Czerwiec, Frank S;
Sergeyeva, Olga;
Ouyang, John;
Shoaf, Susan

Publication type:

Article

Can we further enrich autosomal dominant polycystic kidney disease clinical trials for rapidly progressive patients? Application of the PROPKD score in the TEMPO trial.

Published in:

Nephrology Dialysis Transplantation, 2018, v. 33, n. 4, p. 645, doi. 10.1093/ndt/gfx188

By:

Cornec-Le Gall, Emilie;
Blais, Jaime D.;
Irazabal, Maria V.;
Devuyst, Olivier;
Gansevoort, Ron T.;
Perrone, Ron D.;
Chapman, Arlene B.;
Czerwiec, Frank S.;
Ouyang, John;
Heyer, ChristinaM.;
Senum, Sarah R.;
LeMeur, Yannick;
Torres, Vicente E.;
Harris, Peter C.

Publication type:

Article

Multicenter, open-label, extension trial to evaluate the long-term efficacy and safety of early versus delayed treatment with tolvaptan in autosomal dominant polycystic kidney disease: the TEMPO 4:4 Trial.

Published in:

Nephrology Dialysis Transplantation, 2018, v. 33, n. 3, p. 477, doi. 10.1093/ndt/gfx043

By:

Torres, Vicente E.;
Chapman, Arlene B.;
Devuyst, Olivier;
Gansevoort, Ron T.;
Perrone, Ronald D.;
Dandurand, Ann;
Ouyang, John;
Czerwiec, Frank S.;
Blais, Jaime D.

Publication type:

Article

Tolvaptan suppresses monocyte chemotactic protein-1 excretion in autosomal-dominant polycystic kidney disease.

Published in:

Nephrology Dialysis Transplantation, 2017, v. 32, n. 6, p. 969, doi. 10.1093/ndt/gfw060

By:

Grantham, Jared J.;
Chapman, Arlene B.;
Blais, Jaime;
Czerwiec, Frank S.;
Devuyst, Olivier;
Gansevoort, Ron T.;
Higashihara, Eiji;
Krasa, Holly;
Wen Zhou;
Ouyang, John;
Perrone, Ronald D.;
Torres, Vicente E.

Publication type:

Article

Albuminuria and tolvaptan in autosomal-dominant polycystic kidney disease: results of the TEMPO 3:4 Trial.

Published in:

Nephrology Dialysis Transplantation, 2016, v. 31, n. 11, p. 1887, doi. 10.1093/ndt/gfv422

By:

Gansevoort, Ron T.;
Meijer, Esther;
Chapman, Arlene B.;
Czerwiec, Frank S.;
Devuyst, Olivier;
Grantham, Jared J.;
Higashihara, Eiji;
Krasa, Holly B.;
Ouyang, John;
Perrone, Ronald D.;
Torres, Vicente E.

Publication type:

Article

F111. EARLY IMPROVEMENT OF PANSS ITEMS IN PATIENTS WITH SCHIZOPHRENIA TREATED WITH BREXPIPRAZOLE: A POST HOC ANALYSIS OF THREE RANDOMIZED STUDIES.

Published in:

Schizophrenia Bulletin, 2019, v. 45, p. S296, doi. 10.1093/schbul/sbz018.523

By:

Weiss, Catherine;
Meehan, Stine Rasmussen;
Ouyang, John;
Hobart, Mary

Publication type:

Article

Pharmacokinetics and Pharmacodynamics of Tolvaptan in Autosomal Dominant Polycystic Kidney Disease: Phase 2 Trials for Dose Selection in the Pivotal Phase 3 Trial.

Published in:

Journal of Clinical Pharmacology, 2017, v. 57, n. 7, p. 906, doi. 10.1002/jcph.880

By:

Shoaf, Susan E.;
Chapman, Arlene B.;
Torres, Vicente E.;
Ouyang, John;
Czerwiec, Frank S.

Publication type:

Article

A Long-Term, Open-Label Study to Evaluate the Safety and Tolerability of Brexpiprazole as Maintenance Treatment in Adults with Schizophrenia.

Published in:

International Journal of Neuropsychopharmacology, 2018, v. 21, n. 5, p. 433, doi. 10.1093/ijnp/pyy002

By:

Forbes, Andy;
Hobart, Mary;
Ouyang, John;
Shi, Lily;
Pfister, Stephanie;
Hakala, Mika

Publication type:

Article

Efficacy and Safety of Brexpiprazole (OPC-34712) as Maintenance Treatment in Adults with Schizophrenia: a Randomized, Double-Blind, Placebo-Controlled Study.

Published in:

International Journal of Neuropsychopharmacology, 2017, v. 20, n. 1, p. 11, doi. 10.1093/ijnp/pyw076

By:

Fleischhacker, W. Wolfgang;
Hobart, Mary;
Ouyang, John;
Forbes, Andy;
Pfister, Stephanie;
McQuade, Robert D.;
Carson, William H.;
Sanchez, Raymond;
Nyilas, Margareta;
Weiller, Emmanuelle

Publication type:

Article

Effects of tolvaptan on dyspnoea relief from the EVEREST trials.

Published in:

European Heart Journal, 2009, v. 30, n. 18, p. 2233

By:

Pang, Peter S.;
Konstam, Marvin A.;
Krasa, Holly B.;
Swedberg, Karl;
Zannad, Faiez;
Blair, John E.A.;
Zimmer, Christopher;
Teerlink, John R.;
Maggioni, Aldo P.;
Burnett, John C.;
Grinfeld, Liliana;
Ouyang, John;
Udelson, James E.;
Gheorghiade, Mihai

Publication type:

Article

TIN2 Functions with TPP1/POT1 To Stimulate Telomerase Processivity.

Published in:

Molecular & Cellular Biology, 2019, v. 39, n. 21, p. 1, doi. 10.1128/MCB.00593-18

By:

Pike, Alexandra M.;
Strong, Margaret A.;
Ouyang, John Paul T.;
Greider, Carol W.

Publication type:

Article

Comparisons of global tests on intersection hypotheses and their application in matched parallel gatekeeping procedures.

Published in:

Journal of Biopharmaceutical Statistics, 2020, v. 30, n. 4, p. 593, doi. 10.1080/10543406.2019.1696355

By:

Ouyang, John;
Zhang, Peter;
Carroll, Kevin J.;
Lee, Jennifer;
Koch, Gary

Publication type:

Article

Clinical Pattern of Tolvaptan-Associated Liver Injury in Subjects with Autosomal Dominant Polycystic Kidney Disease: Analysis of Clinical Trials Database.

Published in:

2015

By:

Watkins, Paul;
Lewis, James;
Kaplowitz, Neil;
Alpers, David;
Blais, Jaime;
Smotzer, Dan;
Krasa, Holly;
Ouyang, John;
Torres, Vicente;
Czerwiec, Frank;
Zimmer, Christopher;
Watkins, Paul B;
Lewis, James H;
Alpers, David H;
Blais, Jaime D;
Smotzer, Dan M;
Torres, Vicente E;
Czerwiec, Frank S;
Zimmer, Christopher A

Publication type:

journal article

Rationale and Design of a Clinical Trial Investigating Tolvaptan Safety and Efficacy in Autosomal Dominant Polycystic Kidney Disease.

Published in:

2017

By:

Torres, Vicente E.;
Devuyst, Olivier;
Chapman, arlene B.;
Gansevoort, Ron T.;
Perrone, Ronald D.;
Ouyang, John;
Blais, Jaime D.;
Czerwiec, Frank S.;
Sergeyeva, Olga

Publication type:

journal article

Coping with missing data in phase III pivotal registration trials: Tolvaptan in subjects with kidney disease, a case study.

Published in:

Pharmaceutical Statistics, 2017, v. 16, n. 4, p. 250, doi. 10.1002/pst.1808

By:

Ouyang, John;
Carroll, Kevin J.;
Koch, Gary;
Li, Junfang

Publication type:

Article

The effect of tolvaptan on autosomal dominant polycystic kidney disease patients: a subgroup analysis of the Japanese patient subset from TEMPO 3:4 trial.

Published in:

Clinical & Experimental Nephrology, 2015, v. 19, n. 5, p. 867, doi. 10.1007/s10157-015-1086-2

By:

Muto, Satoru;
Kawano, Haruna;
Higashihara, Eiji;
Narita, Ichiei;
Ubara, Yoshifumi;
Matsuzaki, Takayuki;
Ouyang, John;
Torres, Vicente;
Horie, Shigeo

Publication type:

Article

ShinyCell: simple and sharable visualization of single-cell gene expression data.

Published in:

Bioinformatics, 2021, v. 37, n. 19, p. 3374, doi. 10.1093/bioinformatics/btab209

By:

Ouyang, John F;
Kamaraj, Uma S;
Cao, Elaine Y;
Rackham, Owen J L

Publication type:

Article

GeneSwitches: ordering gene expression and functional events in single-cell experiments.

Published in:

Bioinformatics, 2020, v. 36, n. 10, p. 3273, doi. 10.1093/bioinformatics/btaa099

By:

Cao, Elaine Y;
Ouyang, John F;
Rackham, Owen J L

Publication type:

Article

Short-term effects of tolvaptan on renal function and volume in patients with autosomal dominant polycystic kidney disease.

Published in:

Kidney International, 2011, v. 80, n. 3, p. 295, doi. 10.1038/ki.2011.119

By:

Irazabal, Maria V.;
Torres, Vicente E.;
Hogan, Marie C.;
Glockner, James;
King, Bernard F;
Ofstie, Troy G.;
Krasa, Holly B.;
Ouyang, John;
Czerwiec, Frank S.

Publication type:

Article

Recruitment of mRNAs to P granules by condensation with intrinsically-disordered proteins.

Published in:

eLife, 2020, p. 1, doi. 10.7554/eLife.52896

By:

Lee, Chih-Yung S.;
Putnam, Andrea;
Tu Lu;
ShuaiXin He;
Ouyang, John Paul T.;
Seydoux, Geraldine

Publication type:

Article

Single cell analysis in head and neck cancer reveals potential immune evasion mechanisms during early metastasis.

Published in:

Nature Communications, 2023, v. 14, n. 1, p. 1, doi. 10.1038/s41467-023-37379-y

By:

Quah, Hong Sheng;
Cao, Elaine Yiqun;
Suteja, Lisda;
Li, Constance H.;
Leong, Hui Sun;
Chong, Fui Teen;
Gupta, Shilpi;
Arcinas, Camille;
Ouyang, John F.;
Ang, Vivian;
Celhar, Teja;
Zhao, Yunqian;
Tay, Hui Chen;
Chan, Jerry;
Takahashi, Takeshi;
Tan, Daniel S. W.;
Biswas, Subhra K.;
Rackham, Owen J. L.;
Iyer, N. Gopalakrishna

Publication type:

Article

SenMayo transcriptomic senescence panel highlights glial cells in the ageing mouse and human retina.

Published in:

NPJ Aging, 2024, v. 10, n. 1, p. 1, doi. 10.1038/s41514-024-00187-9

By:

Suresh, Samyuktha;
Karthik, Gayathri;
Ouyang, John F.;
Chrysostomou, Vicki;
Tang, See Aik;
Petretto, Enrico;
Crowston, Jonathan G.;
Bell, Katharina C.

Publication type:

Article

Transcriptomic imputation of genetic risk variants uncovers novel whole-blood biomarkers of Parkinson's disease.

Published in:

NPJ Parkinson's Disease, 2024, v. 10, n. 1, p. 1, doi. 10.1038/s41531-024-00698-y

By:

Chew, Gabriel;
Mai, Aaron Shengting;
Ouyang, John F.;
Qi, Yueyue;
Chao, Yinxia;
Wang, Qing;
Petretto, Enrico;
Tan, Eng-King

Publication type:

Article

Brexpiprazole in patients with schizophrenia: overview of short- and long-term phase 3 controlled studies.

Published in:

Acta Neuropsychiatrica, 2017, v. 29, n. 5, p. 278, doi. 10.1017/neu.2016.57

By:

Marder, Stephen R.;
Hakala, Mika Juhani;
Josiassen, Mette Krog;
Zhang, Peter;
Ouyang, John;
Weiller, Emmanuelle;
Weiss, Catherine;
Hobart, Mary

Publication type:

Article

scPanel: a tool for automatic identification of sparse gene panels for generalizable patient classification using scRNA-seq datasets.

Published in:

Briefings in Bioinformatics, 2024, v. 25, n. 6, p. 1, doi. 10.1093/bib/bbae482

By:

Xie, Yi;
Yang, Jianfei;
Ouyang, John F;
Petretto, Enrico

Publication type:

Article

Transcriptional signature in microglia associated with Aβ plaque phagocytosis.

Published in:

Nature Communications, 2021, v. 12, n. 1, p. 1, doi. 10.1038/s41467-021-23111-1

By:

Grubman, Alexandra;
Choo, Xin Yi;
Chew, Gabriel;
Ouyang, John F.;
Sun, Guizhi;
Croft, Nathan P.;
Rossello, Fernando J.;
Simmons, Rebecca;
Buckberry, Sam;
Landin, Dulce Vargas;
Pflueger, Jahnvi;
Vandekolk, Teresa H.;
Abay, Zehra;
Zhou, Yichen;
Liu, Xiaodong;
Chen, Joseph;
Larcombe, Michael;
Haynes, John M.;
McLean, Catriona;
Williams, Sarah

Publication type:

Article